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MIKROENKAPSULASI EKSTRAK FORMULA PEGAGAN-KUMIS KUCING-SAMBILOTO SEBAGAI INHIBITOR Angiotensin I Converting Enzyme SECARA In Vitro Rani, Ismarani; Pradono, Dyah Iswantini; Darusman, Latifah K
CEFARS : JURNAL AGRIBISNIS DAN PENGEMBANGAN WILAYAH Vol. 3 No. 1 (2011): CEFARS : JURNAL AGRIBISNIS DAN PENGEMBANGAN WILAYAH
Publisher : Fakultas Pertanian Universitas Islam 45 (UNISMA) Bekasi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chitosan microencapsulation contained extract formula pegagan-kumis kucingsambiloto was resulted from ionic gelation process. Chitosan microencapsulation wasresulted by cleaning bath type of ultrasonication and homogenization methods. Optimum condition obtained at 2% of chitosan concentration (w/v) and 50 mL (v/v) of extract formula. The yields of chitosan microparticles was 64.24%. Characterization by SEM at 5000× magnification showed that the particle size of chitosan microparticles was not uniform. Chitosan microparticles without and contained extract formula had diameters between 0.40 μm-8.5 μm and 1 μm-6 μm, respectively. Each chitosan microparticles contained extract formula and extract formula had the ACE inhibitory activity of 78.41 %, and 75.73 %, respectively, while the captopryl as an positive control had ACE inhibitory activity of 75.24 %. Wave number peaks of chitosan spectrum was different with microparticles spectrum by using of FTIR analysis. Chitosan microparticles-sodium tripolyphosphate (STP) contained extract formula had absorbance bands of 1652.32 cm-1 (C=O) and 1565.63 cm-1 (C=C, aromatic group of benzene). New absorbance bands also appeared at wave numbers of 1153.82 cm-1 and 1154.66 cm-1 which showed absorbance band of P=O group from STP compound.
Effect of Local Microorganism Utilization to Increase Productivity of Javanese Turmeric (Curcuma xanthorriza Roxb.) Faiza, Lucky Lia; Arifin, Poppy F.; Nurcholis, Waras; Ridwan, Taufik; Darusman, Latifah K; Susilowidodo, Raphael Aswin; Wisastra, Rosalina
Jurnal Jamu Indonesia Vol. 3 No. 2 (2018): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v3i2.55

Abstract

The quality of javanese turmeric as one of the most widely use herb in Indonesian traditional medicine, is often ignored and unoptimized. Therefore, research on Javanese turmeric cultivation become critical to be performed.One of crucial aspect is sufficiency of water and nutrients to increase rhizome productivity during vegetative period. Therefore, fertilization plays an important role in increasing soil macronutrients content and ultimately enhance Javanese turmeric’s quality.The aim of this research is to determine the potential of addition local microorganism (LMO) solution as an organic fertilizer on rhizome production and bioactive content of Javanese Turmeric . The research on LMO application for Javanese turmeric plantation was conducted at Soho Center of Excellence in Herbal Research (SCEHR). LMO was made by utilizing local waste of snail and fruits collected from around plantation area. Three different groups of treatment were applied, one group as a control and two groups were treated by additional LMO along vegetative period. The measured parameters were weight of rhizome, curcuminoid and xanthorrhizol levels. The results showed that LMO addition to the regular fertilization able to increase Javanese turmeric productivity and shorten both vegetative and generative period of time while maintain its quality. It can be concluded that LMO application is also good approach for both field, Javanese turmeric agriculture and natural medicine.
FABRICATION AND ANALITICAL PERFORMANCE EVALUATION OF CARBON PASTE ELECTRODE USING CYCLIC VOLTAMMETRY Wahyuni, Wulan Tri; Darusman, Latifah K; Herliani, Desi
Analit : Analytical and Environmental Chemistry Vol. 2, No. 02 October (2017) Analit : Analytical and Environmental Chemistry
Publisher : Jurusan Kimia FMIPA Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/aec.v2i2.2017.p

Abstract

Penelitian ini bertujuan mengembangkan metode pembuatan Elektrode Pasta Karbon (EPK) yang memberikan respon voltammetri yang optimum serta menguji kinerjanya menggunakan larutan K3[Fe(CN)6] secara voltammetri siklik. Parameter yang dioptimasi meliputi nisbah komposisi grafit dan parafin, pemanasan grafit, sonikasi campuran grafit dan parafin, waktu penggerusan, dan lama penyimpanan EPK sebelum digunakan. Respons terbaik diperoleh saat EPK dibuat dengan nisbah campuran grafit dan parafin sebesar 7 : 3 dan grafit yang dipanaskan terlebih dahulu pada suhu 105 C selama 2 jam. Campuran grafit dan parafin terbaik diperoleh setelah sonikasi selama 30 menit dan waktu penggerusan selama 45 menit. EPK yang disimpan 2 hari sebelum digunakan menghasilkan respons terbaik. Pengukuran K3[Fe(CN)6] pada rentang konsentrasi 0,1 – 125 mM menunjukkan respon linear dengan koefisien determinasi (R2) sebesar 0,9998 dan 0,9991, masing-masing untuk arus puncak oksidasi dan reduksi dengan simpangan baku relatif (%SBR) sebesar 2,0% pada reaksi oksidasi dan 1,07% pada reaksi reduksi. EPK yang dihasilkan menunjukkan  stabilitas yang baik pada pemakaian selama 7 hari berturut-turut dan 96 kali pengukuran