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PENGARUH VARIASI KONSENTRASI NATRIUM TRIPOLIFOSFAT PADA NANOEMULSI METODE GELASI IONIK EKSTRAK ETANOL Sargassum sp.: EFFECT OF VARIATION OF SODIUM TRIPOLYPHOSPHATE CONCENTRATION ON NANOEMULSION IONIC GELATION METHOD OF ETHANOL EXTRACT Sargassum sp. Agung Giri Samudra; Nurfijrin Ramadhani; Reza Pertiwi; Apriza Hongko Putra; Bambang Hernawan Nugroho; Fathnur Sani K
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 2 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i2.361

Abstract

Penggunaan nanoemulsi sediaan farmasi diharapkan dapat meningkatkan penetrasi dan absorpsi bahan aktif tanpa perlu menambahkan eksipien penetrasi lain dan memiliki luas permukaan yang besar sehingga lebih efektif sebagai sistem pembawa. Natrium tripolifosfat dikenal sebagai zat pengikat silang yang paling baik untuk berinteraksi dengan polikation kitosan untuk membentuk nanoemulsi. Mengetahui karakteristik ekstrak etanol Sargassum sp. yang dikorporasikan ke dalam bentuk nanoemulsi dengan adanya variasi konsentrasi natrium tripolifosfat. Nanoemulsi metode gelasi ionik menggunakan magnetik stirer kecepatan 750 rpm dengan perbandingan ekstrak etanol Sargassum sp.: larutan kitosan: larutan natrium tripolifosfat: larutan tween formula 1 (0,25 gram; 0,1% 18 mL; 0,2% 9 mL; 0,5% 3mL); formula 2 (0,25 gram; 0,1% 18 mL; 0,4% 9 mL; 0,5% 3 mL) dan formula 3 (0,25 gram; 0,1% 18 mL; 0,8% 9 mL; 0,5% 3 mL). Karateristik nanoemulsi berupa ukuran partikel dan nilai zeta potensial. Koloid nanoemulsi yang terbentuk dikarakterisasi berupa ukuran partikel (nm); potensial zeta (mV) yaitu formula 1 (149,1±3,5 nm; 16.5±0,3 mV); formula 2 (107,1±0,5 nm; 12,7±0,1 mV); formula 3 (101,7±0,7 nm; 8,2±0,2 mV). Variasi konsentrasi larutan natrium tripolifosfat mempengaruhi ukuran partikel dan nilai potensial zeta. Semakin tinggi konsentrasi larutan natrium tripolifosfat maka memperkecil ukuran patikel dan potensial zeta. Ukuran partikel terkecil pada formula 3, sedangkan nilai potensial zeta terbaik yang paling mendekati 30 mV pada formula 1.
Analisis Isi Lambung Ikan Mungkus (Sicyopterus cynocephalus: GOBIIDAE) untuk Menentukan Food and Feeding Habit di Sungai Padang Guci Kaur Apriza Hongko Putra; Dian Fita Lestari; Sipriyadi Sipriyadi
Jurnal Biosilampari : Jurnal Biologi Vol 6 No 1 (2023): Jurnal Biosilampari : Jurnal Biologi
Publisher : Universitas PGRI Silampari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62112/biosilampari.v6i1.53

Abstract

The aim of this research was to reveal the natural foods of S. cynocephalus from Padang Guci River, Kaur Regency. This research was conducted by using stratified random sampling by catching 75 individuals from its habitat divided by 3 stations such as Station I (upstream), Station II (middle stream) and Station III (downstream). Sampling was conducted using fishing trap and fishing net and then stomach dissection was done in Laboratory of Biology, FMIPA UNIB to identify food variety, body ratio, digestive tract ratio and frequency of food occurrences of fish samples (each 25 samples per station). In addition, water quality parameters were also measured. Based on the result, the data showed that there is a different in body development of mungkus fish which in Station I was positive allometry. In contrast, station II and III showed negative allometry. Based on frequency of food occurrence. The highest occurrence was Cosmarium decoratum (72 %) and the lowest was Synedra. All obtained food were classified as algae. Analysis of digestive tract and body ratio revealed that S. cynocephalus was categorized as herbivore fish with the ratio 3.72-5.34. The measurement of abiotic factor indicated that all parameters were still fulfil water quality standard to support the sustainability of Mungkus life in Padang Guci River.