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All Journal Jurnal Kesehatan Andalas The Indonesian Biomedical Journal BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan)

Mardhatillah Sariyanti

Departemen Mikrobiologi Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Bengkulu

Author-ID : 5579910

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Nursing Public Health Social Sciences Other

Published : 6 Documents Claim Missing Document

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Articles

Perbandingan Tingkat Keparahan Infeksi Sekunder Virus Dengue pada Keempat Serotipe di Indonesia: Systematic Review Annelin Kurniati; Ahmad Fandi; Mardhatillah Sariyanti; Ety Febrianti; Debie Rizqoh
Jurnal Kesehatan Andalas Vol 10, No 1 (2021): Online March 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i1.1615

Secondary infection with the dengue virus causes mild to severe manifestations. The distribution of dengue virus serotypes varies in various areas and can change over time. There are four dengue serotypes, namely DENV-1, DENV-2, DENV-3 and DENV-4. Objectives: To knew the distribution of virus serotypes in an area and determined the pathogenesis of the disease, which can cause severe manifestations in patients with secondary infections. Methods: The data taken is the severity of secondary infections and dengue serotypes. The literature search was performed on PMC and Cochrane. Search criteria were performed using keywords (secondary infection * OR secondary dengue infection *) AND (Dengue Virus * OR Dengue Infection * OR Dengue * OR DENV) AND (Serotype * OR Serogroup) AND (severe dengue * OR severity * OR severity of illness indexs * OR dengue fever * OR dengue haemorrhage fever * OR dengue shock syndrome * OR DF * OR DHF * OR DSS *) AND (Indonesia *). Results: Literature study search found 387 literature with five studies conducted the analysis. From the results of the analysis, it was found that secondary infections were more common in patients with recurrent dengue infection with serotype 2 (DENV-2), serotype 3 (DENV-3) and serotype 4 (DENV-4). Conclusion: Secondary infection of dengue virus serotype 2 (DENV-2) and serotype 3 (DENV-3) can cause severe dengue infection.Keywords: Dengue Virus, Indonesia, Secondary Infection, Serotype, Severity

Analisis Faktor Abiotik Sumber Air Sumur di Lingkungan Kawasan Pesisir Pantai : Studi Kasus Kawasan Kampus Universitas Bengkulu Samsul Bahri; Budi Harlianto; Helfi Eka Saputra; Apriza Hongko Putra; Mardhatillah Sariyanti
BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Vol 3 No 2 (2020): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

University of Bengkulu is a communal area located on the west coast of Sumatra. The main water sources to support activities at UNIB come from shallow wells (dug) and deep wells (drilled). This study aims to analyze the physical and chemical parameters of dug and bore water wells in the environment of UNIB’s campus. Water quality testing for dug and bore wells includes several treatments. Water quality analysis using the Indonesian National Standard method. The results of water quality testing for dug and bore wells founded several physical and chemical parameters exceeding Class II water quality standards. The results of the testing of the quality of water in the TSS 1 dug well had exceeded the quality standard. The results of testing the quality of dug wells 1, 2, 3 and 4 pH and phosphate parameters had exceeded the quality standard. The results of testing the quality of dug 2 meter wells dug DHL had exceeded the quality standard. The results of the testing of the quality of water in a borehole 1 phosphate parameter had exceeded the quality standard. The results of water quality testing for boreholes 2 and 3 Fe parameters had exceeded the quality standard. Dug and bore well water sources in the UNIB environment can be used for drinking water, drinking freshwater fish, livestock, irrigating crops, and / or other purposes that require the same water quality as these uses. Keywords: Physical and Chemical Parameters, Deep Water, Shallow Water, Quality Standard

Telekonsultasi Dalam Rangka Pemutusan Rantai Penularan Covid-19 di Kota Bengkulu Dessy Triana, M. Biomed; Hardiansyah Hardiansyah; Sri Yunita; Miftahul Haniyah; Enny Nugraheni Sulistiyorini; Riry Ambarsarie; Rizkianti Anggraini; Elvira Yunita; Mardhatillah Sariyanti
DHARMA RAFLESIA Vol 19, No 2 (2021): DESEMBER (ACCREDITED SINTA 5)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/dr.v19i2.18373

Coronavirus Disease-19 (Covid-19) is a disease that has become a global epidemic. The World Health Organization (WHO) has declared Covid-19 a pandemic. Indonesia declared the status of the Covid-19 disease to be an Emergency Response. Supporting the social distancing, the right strategy is needed to continue implementing health services amid the Covid-19 pandemic. This activity aimed to provide knowledge related to Covid-19 to the community and health consultations and medical advice through applications (teleconsultation) to minimize patients queuing at Health Service Facilities directly. The activity partners were the Indonesian Medical Association (IDI) Bengkulu City Branch, Bengkulu City Health Office, and the Indonesian Red Crescent (BSMI) Bengkulu City Region. The method of this activity was to provide socialization, health consultation and medical advice through applications (teleconsultation) regarding the spread, transmission and prevention of Covid-19 from May 1 to August 31 2020. The number of participants was 41 people from Bengkulu City. The highest number of diseases consulted were acute respiratory infections (38.7%.) and Covid-19 independent protocol consultation (31.58%.) Teleconsultation can be continued and developed into a patentable application. Application development is indispensable in responding to the challenges of the health world in the digital era.

Perbandingan Tingkat Keparahan Infeksi Primer Virus Dengue Serotipe 1, 2, 3 dan 4 di Indonesia: Systematic Review Mardhatillah Sariyanti; Nur Fitri; Ety Febrianti; Annelin Kurniati; Debie Rizqoh
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 6, No 1 (2021)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Dengue virus infection (DENV) circulates in various hyperendemic and endemic areas that has increase mortality year by year. Indonesia is the second-largest country which is endemic to dengue infection between 30 other countries in the world. There are four circulating dengue virus (DENV) serotypes, namely DENV-1, DENV-2, DENV-3, and DENV-4. Each serotype shows a different clinical manifestation and severity. This systematic review aims to compare the severity of dengue virus primary infection and serotype 1,2,3,and 4. Data were collected based on studies of the severity of primary infections caused by various DENV serotypes in Indonesia. Data was searched using a database in the form of Pubmed and Chocrane. The keywords used are (Primary dengue infection OR dengue primary infection) AND (serotype OR serogroup OR serotype dengue)) AND (severity OR severe dengue* OR severity of illness index* OR clinical manifestations OR clinical features OR clinical characteristics) AND Indonesia. Based on search results, we obtained 7 studies out of 699 studies. 7 studies found that there are differences in serotype circulation in Indonesia. DENV-3 is dominant in 7 cities in Indonesia, while DENV-1 is dominant in Surabaya, Bali, and Jambi. Dengue fever shows a greater percentage than DHF / DSS. The proportion of severity is lower in primary infections.

Association between Body Mass Index and Type of Infection on the Severity of Dengue Infection in Bengkulu City, Indonesia Annelin Kurniati; Dessy Triana; Enny Nugraheni Sulistiyorini; Mardhatillah Sariyanti; Gayatri Ghea Wirastari
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 6, No 3 (2021)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Background: Dengue virus infection is a serious global health problem. The incidence has increased rapidly within the last 50 years. The clinical manifestations vary from Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF), to Dengue Shock Syndrome (SSD). Some of the influencing factors are the Body Mass Index (BMI) and the type of dengue infection. The study aimed to determine the association between BMI and type of infection on the severity of dengue infection in adulthood.Methods: The study used a cross-sectional design with a total sample of 39 patients diagnosed with dengue infection and fulfilling the inclusion criteria. The sampling technique was consecutive sampling. The data analysis used was the Spearman correlation test. Data collection was conducted by distributing research form which cover sample characteristics, BMI values, clinical manifestations, types of infection and the severity of dengue infection.Results: The total of subject obtained was 37 respondents (23 male and 14 female). The average BMI value was 24.65 ± 5.08. The most common clinical manifestations were fever (100%), nausea/vomiting (91.8%), headache (89.1%), myalgia (89.1%), and arthralgia (72.9%). Most cases of dengue infection were in the normal BMI group and the highest degree of severity was DD. There was a significant relationship with a fairly strong correlation value between BMI and dengue severity (p=0.003; r=0.478). However, there was no significant relationship between the type of infection (p=0.987; r=0.03) with the level of dengue severity.Conclusion: Knowing the risk factors as predictors of dengue severity is very necessary in order to handle dengue infection quickly and accurately.

Probiotic Lactobacillus acidophilus FNCC 0051 Improves Pancreatic Histopathology in Streptozotocin-induced Type-1 Diabetes Mellitus Rats Mardhatillah Sariyanti; Tiara Ayoe Andita; Noor Diah Erlinawati; Elvira Yunita; Ahmad Azmi Nasution; Kartika Sari; Nikki Aldi Massardi; Sylvia Rianissa Putri
The Indonesian Biomedical Journal Vol 14, No 4 (2022)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v14i4.2047

BACKGROUND: Intestinal microbial dysbiosis and its metabolites can affect the immune activity of intestinal mucosal cells, causing insulitis and pancreatic β-cell death. Probiotic Lactobacillus acidophilus plays an important role in reducing inflammatory cytokines, hence improves oxidative stress that affects pancreatic β-cell apoptosis. Current study examined the feature of pancreatic histopathology affected by the administration of probiotic L. acidophilus in rats with type-1 diabetes mellitus (DM) induced by streptozotocin (STZ).METHODS: Twelve rats were induced by STZ at double dose of 50 mg/kgBB before administered with probiotic L. acidophilus at a dose of 1.5x10 8 or 1.5x10 9 CFU/mL/day, while other 4 rats were used as control. After 21 days of the L. acidophilus treatment, the average of fasting blood glucose (FBG) levels of rats were measured, then the pancreatic histopathology was assessed to evaluate the degree of insulitis in islet of Langerhans.RESULTS: The induction of STZ had been succeeded to increase blood glucose levels, which indicate DM condition. The highest FBG level after 21 days of treatment was found in DM group with glucose level of 512±81.51 mg/dL. The administration of probiotic L. acidophilus during 21 days treatment at both dose 1.5x10 8 and 1.5x10 9 CFU/mL/day significantly improved pancreatic histopathology (p=0.04 and p=0.034, respectively), with significant decrease on insulitis scores compared to DM group.CONCLUSION: The administration of L. acidophilus at both dose of 1.5x10 8 and 1.5x10 9 CFU/mL/day for 21 days can improve pancreatic histopathology of type-1 DM rats induced by STZ, therefore probiotic L. acidophilus may be potential as supplementation treatment for type-1 DM.KEYWORDS: Lactobacillus acidophilus, pancreatic histopathology, streptozotocin, type-1 diabetes mellitus

Co-Authors Ahmad Azmi Nasution Ahmad Fandi Annelin Kurniati Annelin Kurniati Annelin Kurniati Apriza Hongko Putra Debie Rizqoh Dessy Triana Elvira Yunita Enny Nugraheni Ety Febrianti Ety Febrianti Gayatri Ghea Wirastari Hardiansyah Hardiansyah Harlianto, Budi Helfi Eka Saputra Kartika Sari Miftahul Haniyah Nikki Aldi Massardi Noor Diah Erlinawati Nur Fitri Riry Ambarsarie Rizkianti Anggraini Samsul Bahri Sri Yunita Sylvia Rianissa Putri Tiara Ayoe Andita

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