Article Per Year (5 Year)
p-Index From 2021 - 2026
1.405
P-Index
This Author published in this journals
All Journal Jurnal Kebidanan Jurnal Kesehatan Lingkungan indonesia JURNAL PROMOSI KESEHATAN INDONESIA Jurnal Kesehatan Masyarakat Jurnal Manajemen Kesehatan Indonesia Jurnal Ilmiah Mahasiswa Jurnal Kesehatan Ibu dan Anak Jurnal Kesehatan Medica Hospitalia Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Jurnal Aisyah : Jurnal Ilmu Kesehatan JHE (Journal of Health Education) Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Dharminto Dharminto
Bagian Biostatistik Dan Kependudukan Fakultas Kesehatan Masyarakat Universitas Diponegoro, Jl. Prof. H. Soedarto, S.H.,Tembalang, Semarang, Indonesia | Universitas Diponegoro
Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Published : 71 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Medica Hospitalia

 1 
Curcumin for Quality of Life of Multiple Myeloma Patients: a Randomized, Placebo-Controlled Trial: Curcumin for Quality of Life of Multiple Myeloma Patients: a Randomized, Placebo-Controlled Trial Hendrawati, Anindita Rosenda Eka; Santosa, Damai; Dharminto, Dharminto; Suharti, Catharina
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 2 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.578 KB) | DOI: 10.36408/mhjcm.v9i2.757

Abstract

Background : The main goal of multiple myeloma (MM) therapy is to control the disease, prolong the survival, and improve the life quality. Curcumin affects pro-inflammatory cytokines. There is no research yet that has been conducted to evaluate the effects of curcumin on increasing MM patient's life quality. Objective of this study is to evaluate the effect of curcumin on increasing MM patients' life quality. Methods : Of 24 MM patients were enrolled and were divided randomly into treatment groups (n=12) and controls (n=12). Patients in treatment group received melphalan 4 mg/m2, prednisone 40 mg/m2 (MP) for 7 days and curcumin 8 grams/day for 28 days. The control group received MP and placebo. Quality of life (QoL) scores were measured in early diagnosis and after 4 cycles of treatment. The difference between two groups was analyzed using Mann-Whitney U-Test or Independent T Test. Results : The role function score of the treatment group was better than control. There is a significant difference function score of patients between the treatment and control group, at baseline and 4 cycles treatment (41.66 ± 3.85 vs. 23.61 ± 3.36; 95.83 ± 1.03 vs 76.39 ± 2.51; p=0.022). There was significantly different of insomnia score between treatment and control goup at baseline and the end 4 cycles (41.67 ± 3.79 vs 58.33 ± 3.51; 9.72 ± 1.5 vs 25 ± 1.32; p=0.02). Conclusion : The addition of curcumin in myeloma patients enhances the QoL score, role function score and lowered symptom insomnia.
Co-Authors Aditya Imam Efendi Afritia, Mia Ali Djamhuri Angga Dwi Sulistya Anis Nur Halimah Anna Himmatin Nisa Annisa' Arifatul Hikmah Ardiana Nur Aini Atik Mawarni Audina, Alfin Billy Suyatman Cahya Tri Purnami Cahya Tri Purnami Catharina Suharti Celline Oktiani Corry Wahyuni Hidayat Damai Santosa Daru Lestantyo Dianita Desti Kartikasari Djoko Nugroho Djoko Nugroho Duhita Wikalaili Enzimatia Erni Yuliastuti Farid Agushybana Farid Agusyahbana Farid Agusyahbana, Farid Farid Agusybana Farid Farid Agushybana Fitria Agustina Frida Cahyaningrum, Frida Hanik Machfudloh Hendrawati, Anindita Rosenda Eka Hernayanti, Munica Rita Imani Lia Purnandias Imaroh, Istiana Islahul Imelsa Ika Wulandari Indartik Mamnuah Isnaini Avia Nita ita rahmaningtyas Ivana Anggun Puspita Jessie Novriani Lentho Kadina Alifianur Khairir Rizani Kurnianingsih Kurnianingsih Kurniawati, Yacinta Puji M Adam, T.Ria Marriagewati Martha Irene Kartasurya Menik Samiyati Meuthika Noor Fitriyana, Meuthika Mia Afritia Minanda Oktariza Mohammad Zen Rahfiludin Mufidatul Khasanah Muhaamad Luqman Anshori Munica Rita Hernayanti Naomi Batmomolin Nery Ermaya Nisa Novaeni Nivia Cemerlang Rinjani Novita Haloho Novita Triani Nur Afifah Azhari Nur Endah Wahyuningsih Nuridzin, Dion Zein Okta Nidya Boro Samosir Okvita Sari Paska Aprina Br Purba Pratama, Thoriq Rizqy Putri Setyo Wulandari Putri Tiara Rosha, Putri R. Djoko Nugroho Rade Roro Yuke Rahma Febriani Raden Djoko Nugroho Rahayu Norma Cahyani Rahfiludin, M Zen Rahmadani, Ike Rianasari Rianasari Rida Pertiwi Ritmasari Ritmasari Riza Nurul Husna Rosyida, Lintang Mela Ryan Adiputra S.Pd. M Kes I Ketut Sudiana . Safira Fatichaturrachma Sarah Ayu Tifana Shofia Fadhila Ulfa, Shofia SINTI NURKHOLIFAH Sinti Nurkholifah Siti Fatimah Pradigdo Sri Achadi Nugraheni Sri Winarni Suhartono Suhartono Suhartono Suhartono, Suhartono Suyatno Suyatno Theresia Evelyn Triana Widiastuti Widya Gian Argintha Wiwi Wulan Ndari Yudhy Dharmawan Yudhy Nugroho Yulia Nur Azizah