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Effectiveness, Safety, and Side Effect of Depo Progestin and Depo Vigestron Contraception Budi Santoso; Jimmy Yanuar Annas; Heriyadi Manan; Nizam Albadawi; Marina Marina; Maria Anggraeni; Leli Asih
Jurnal Ners Vol. 8 No. 1 (2013): April 2013
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.142 KB) | DOI: 10.20473/jn.v8i1.3865

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Introduction: Trends in contraceptive injections increased in the last two decades. Hormonal contraceptive injection is available in single or combination dose. However, the products are available more than 1 ml (more than recommendation of WHO). This study aims to determine the effectiveness, safety and side effects of the contraceptive injection Depo Progestin® 3 ml, Depo Vigestron® 3 ml and Depo Vigestron® 1 ml.Methods: This study used randomized controlled clinical trial and open label. The research subject were 900 people in two center, Surabaya and Palembang. The samples were divided into 3 (three) groups, group Depo Progestin® vial 3 ml, group Depo Vigestron® vial 3 ml, and group Depo Vigestron® vial 1 ml. Each of consist 300 women using the "random permutation block". Analysis was performed 5 times, when an initial injection and a schedule of repeated injections in the 3rd, 6th, 9th and 12th month. The data analyzed include weight, blood pressure, menstrual pattern, and the complaints of the patients.Results: From the 900 only 862 valid samples. The results showed no signi fi cant difference between groups Depo Progestin® 3ml, Depo Vigestron® 3 ml and Depo Vigestron® 1 ml. The majority of respondents experienced an increase in weight, but still within normal limits, did not have increased blood pressure, increased menstrual blood volume, Pregnancy didn’t occured to all respondents and found no abnormalities in cervical cytology.Conclusion: Contraceptive injection of Depo Progestin® 3 ml, Depo Vigestron® 3 ml dan Depo Vigestron® 1 ml, have used during 12 months can be concluded that those tree kind of contraception were efective, safe and had no side effect.
The Effect of Early Mobilization on Intestinal Peristaltics in Patients after a Cesarean Section in Kendari City Hospital Andi Herman; Budi Santoso; Esty Yunitasari
Jurnal Ners Vol. 14 No. 3 (2019): Special Issue
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (300.758 KB) | DOI: 10.20473/jn.v14i3.17148

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Background: Cesarean section (CS) is the most significant surgical intervention that affects the central nervous system and that slows down the bowel movement after CS. Intervention in the early period after CS is needed to improve bowel function. This study aims to determine the effect of early mobilization on intestinal peristalsis after cesarean section.Method: This quasi-experimental study was conducted on 72 patients divided into two groups of 36 for the intervention group at Dewi Sartika Public Hospital and for the control group at Kendari Public Hospital. A paired T-test was used for the data analysis.Result: After the intervention, there was a significant improvement in intestinal peristalsis in the intervention group (P<0,05).Conclusion: Early mobilization is an effective intervention to improve intestinal peristalsis in patients after cesarean section.
Perceptions of Working Mothers Toward Breastfeeding Self-Efficacy Sylvia Dwi Wahyuni; Budi Santoso; Mira Triharini; Novri Susan
Jurnal Ners Vol. 15 No. 1Sp (2020): Special Issue
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v15i1Sp.18910

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Introduction: The benefits of exclusive breast feeding are well-documented; however, in Indonesia, breast feeding rates fall well below global recommendations. One of the factors contributing to the low breast-feeding rates is the economic need for many mothers to work and workplaces not providing an adequate environment in which to do so. The aim of the research was to explore the meaning of breastfeeding self-efficacy from the working mothers’ perspective.Methods: The methodology is phenomenology; hence, it is qualitative in nature. The study was conducted in an outpatient’s department in a hospital in Surabaya, Indonesia. Participants: 8 working mothers working outside the home 40 hours a week, attend lactation class, Indonesian, children ages 7 months to 2 years, and baby born healthy.Results: There were six main themes identified in the women’s stories that related to self-efficacy and breastfeeding: 1) the source of breastfeeding self-efficacy, 2) the benefits of breastfeeding, 3) another woman's experience, 4) perception of workplace control,   5) estimated ability of self-confidence, and 6) decision of breastfeeding. The participants who decided to breastfeed for at least two years tended to think positively about breastfeeding.Conclusion: The women had realistic expectations of the commitment that breastfeeding entailed even though they were faced with many workplace obstacles.
Nicotine supplementation blocks oocyte maturation in Rattus norvegicus Meitria Syahadatina Noor; H.M Bahkriansyah; Widjiati Widjiati; Budi Santoso
Universa Medicina Vol. 32 No. 2 (2013)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2013.v32.92-98

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BACKGROUNDIndonesia has the third largest tobacco consumption in the world after China and India. Nicotine as the main component of cigarette smoke has negative effects on the reproductive system, such as oocyte maturation, ovulation, and fertilization, and increasing the diploidy of oocytes. The goal of this researchwas to evaluate the effect of nicotine on oocyte maturation in Rattus norvegicus.METHODSThis was an experimental study with post test only control group design. The subjects were 40 rats selected homogenously and randomly. They were divided into a control group (receiving carboxy-methyl-cellulose sodium and 3 treatment groups (I-III) receiving nicotine subcutaneously for 7 days at dosages of 21 mg/ kgBW, 41 kg/kgBW and 84/kgBW, respectively. The observations comprised oocyte maturation stage, viz. germinal vesicle (GV), germinal vesicle breakdown (GVBD), metaphase I and metaphase II. Data were analyzed by one-way Anova with á=0.05, followed by Tukey’s HSD test.RESULTSOne-way Anova showed significant differences in oocyte  maturation in all groups. Tukey’s HSD test showed that for GV, the differing groups were control and I, control and II, I and III. For GVBD, the differing groups were control and I, I andII, I and III. For metaphase I, the differing groups were control with I, II, and III, I and II, I and III. For metaphase II, the differing groups were control versus I, II, and III, I and II, I and III.CONCLUSIONLow dose of nicotine is capable of affecting oocyte maturation in Rattus norvegicus.
Correlation between Anemia and Preeclampsia in Universitas Airlangga Hospital in 2017 Haris Rasyid Ridho; Muhammad Ilham Aldika Akbar; Widati Fatmaningrum; Budi Santoso
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 12 No. 2 (2021): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V12I22021.66-71

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Introduction: One of the causes of acute kidney injury that is increasingly soaring is preeclampsia syndrome. Globally, the maternal mortality rate reaches 287,000 per year, and preeclampsia is a major contributor. From East Java Provincial Health Office data, per 100,000 pregnancies, 114 had preeclampsia syndrome. Anemia is one of the highest causes of maternal death, the global prevalence of anemia in pregnant women reaches 55.9%. There have not been many significant studies on the effect of anemia with the incidence of preeclampsia.Methods: This was observational analytic study with a case and control design which used a chi-square and fisher exact measurement tool. The data samples were patients of pregnant women who had preeclampsia syndrome categorized as cases, and those who did not have preeclampsia were categorized as controls. The data has been obtained from medical records; these include ages, the number of parities, the number of pregnancies, body mass index (BMI), the number of childbirths, types of preeclampsia, and hemoglobin levels. The data has been obtained from the result of the medical record observations that were processed and analyzed in descriptive of statistics which used percentage and cross tab.Results: The case study group or preeclampsia pregnant women who experienced anemia were 34 patients or 50% of 68 pregnant women and in the control group were 53 patients or 39% of anemia patients out of 136 patients. The chi-square statistical test obtained values (p = 0.133). The samples needed were 68 case groups and 136  cases as controls.Conclusion: There was no relationship between anemia and preeclampsia.
Hubungan Usia Ibu, Jumlah AFC, dan Total Pemberian Gonadotropin terhadap Kualitas Embrio pada Program Fertilisasi In Vitro di Klinik Fertilitas Graha Amerta RSUD Dr. Soetomo Surabaya Periode 2018 – 2019 Chitra Devi Paramita Prasetyawati; Budi Santoso; Hamdani Lunardhi; Hendy Herdarto; Ashon Sa’ad
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.598 KB) | DOI: 10.36418/syntax-literate.v7i1.5742

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Fertilisasi In Vitro merupakan metode untuk mendapatkan kehamilan pada pasangan infertil. Meskipun dengan FIV, angka keberhasilan kehamilan masih cukup rendah yang tentu tidak terlepas dari pengaruh kualitas embrio yang didapatkan. Banyak faktor yang dapat mempengaruhinya, beberapa contohnya adalah usia ibu, jumlah AFC, dan total pemberian gonadotropin. Namun, penelitian mengenai ini masih terbatas terkait literatur dan informasinya. Mengetahui hubungan usia ibu, jumlah AFC, dan total gonadotropin terhadap kualitas embrio pada program FIV di Klinik Fertilitas Graha Amerta Periode 2018- 2019. Penelitian ini menggunakan rancangan cross sectional dengan metode total sampling. Bahan penelitian dari rekam medis pasien yang menjalami program FIV di Klinik Fertilitas Graha Amerta periode 2018-2019. Dari 52 pasangan yang menjalani FIV didapatkan hasil p-value antara usia dengan kualitas embrio baik hari ke-3 0,020, degenerasi 0,003, kualitas embrio baik hari ke-5 0,007, buruk 0,048. AFC dengan kualitas embrio baik hari ke-3 0,000, degenerasi 0,001, kualitas embrio baik hari ke-5 0,001. Total gonadotropin dengan kualitas embrio hari ke-3 dan ke-5 <0,05. Biochemical pregnancy dengan kualitas embrio baik hari ke-3 0,013. Penelitian ini membuktikan bahwa usia ibu dan jumlah AFC berhubungan dengan kualitas embrio. Total pemberian gonadotropin tidak berhubungan dengan kualitas embrio. Namun, apabila diteliti secara bersamaan terdapat hasil pengaruh signifikan secara simultan antara usia ibu, jumlah AFC dan total pemberian gonadotropin terhadap persentase kualitas embrio baik pada hari ke-3 dan hari ke-5.
Sedentary Lifestyle and Overweight in Relation to the Risk of Polycystic Ovary Syndrome in Senior High School Students in Surabaya Shafira Noorania Putri; Budi Santoso; Budiono Budiono
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 2 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I22022.57-61

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Highlights:1. Most senior high school students live a sedentary lifestyle.2. Hyperinsulinemia and hyperandrogenism were related to an increased risk of PCOS in adolescents.3. Sedentary lifestyle and overweight were found to have a significant correlation with increased risk of PCOS in adolescents. AbstractIntroduction: Adolescent polycystic ovary syndrome (PCOS) is one of the endocrine and metabolic disorders characterized by oligomenorrhea and hyperandrogenism. A sedentary lifestyle in adolescence increases the risk of overweight and obesity. Being overweight may increase the risk of PCOS in adolescents by the mechanism of insulin resistance and hyperinsulinemia, which affects the function of adrenal and ovarium androgen production. The increase of androgen has an important effect on PCOS. This study aimed to examine the relationship between a sedentary lifestyle and being overweight as the risk of PCOS in adolescents.Methods: This was an observational analytic study with a cross-sectional design. This study was held at State Senior High School (SMAN) 5 Surabaya from February to April 2020. The sample of this research was chosen by random sampling of all female students in SMAN 5 Surabaya. The data were collected by direct measurement of student’s weight and height and a questionnaire consisting of Global Physical Activities Questionnaire, menstrual cycle, and Ferriman–Gallwey score. The students were stated at risk of PCOS if they had an abnormal uterine bleeding pattern and had Ferriman–Gallwey score ≥5. The data were analyzed using logistic regression analysis.Results: Of 82 students (100%), 32 students were overweight (39%), 5 students had obesity (6.1%), 44 students were performing a sedentary lifestyle (53.7%), 42 students had Ferriman–Gallwey score ≥5 (51.2%), 38 students had an abnormal uterine bleeding pattern (43.3%), and 35 students were at risk of PCOS (42.6%). Logistic regression analysis showed there was a significant relationship between a sedentary lifestyle and the risk of PCOS (p = 0.004) and a significant relationship between being overweight and the risk of PCOS (p < 0.001). People with a sedentary lifestyle have 6.3 folds higher risk of PCOS than normal people, and people with overweight have 16.2 folds higher risk of PCOS than normal people.Conclusion: Sedentary lifestyle and overweight have the role of increasing the risk of PCOS in adolescents.
Pengetahuan Dokter Umum tentang Sindroma Ovarium Polikistik di Puskesmas Surabaya, Indonesia. Julia Elviethasari; Budi Santoso; Budiono; Sulistiawati
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-228

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Introduction: Early detection to diagnose PCOS as a promotive and preventive effort is needed in PHC.Method: By using a descriptive research design that was conducted on one of the general practitioners in the Maternal and Child Health Polyclinic (MCH) in 30 PHC was targeted by PCOS from August - October 2019. Result: Thirty general practitioners participated in filling out the questionnaire. Obtained results based on risk factors divided into three categories 33.33% good, 50% sufficient and 16.67% deficient, for causes 6.67% good, 40% sufficient and 53.33% deficient and clinical symptoms 6.67 good%, 40% sufficient and 53.33% deficient. Conclusion: General practitioners at the PHC had a sufficient level of knowledge for risk factors categorized, causes were lacking and symptoms of clinics were lacking. This was an important finding so that it was necessary to increase the specific knowledge of PCOS for the main steps of early detection in PHC.
An IGF-1 Levels Decrease in SOPK-RI Model Mice After A Low-Carb Diet Ermawati Ermawati; Budi Santoso; Widjiati Widjiati; Hany Puspita Aryani
STRADA : Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v9i2.298

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The aim of this study is to analyze the IGF-1 levels decrease in mice modeled by Polycystic Ovary Syndrome Insulin Resistance post carbohydrate high in protein. True Experimental Design with a Posttest Control Group Design research using 36 tails, female Wistar Rattus Norvegicus Strains, 3 months, 100-200 grams and randomly divided into 3 groups, namely K-(n =12, negative control group), K+(n=12, positive control group) and KP(n=12, treatment group). SOPK-IR modeling is done by mice in the injection of the hormone testosterone provionate at a dose of 100 mg/kg BW for 28 days, on the last day after injection a vaginal swab is performed to identify the condition of diestrus. The measurement of IGF-1 levels used the Enzyme-Linked Immunosorbent Assay method. Data analysis techniques used ANOVA test and LSD post hoc test. The results obtained mean levels of IGF-1 at K- (234.126±32.568) ng/mL, K+ (169.662±30.150) ng/mL, KP (146.528±29.562) ng/mL (p=0.000)
Roy's Adaptation Model Application in Nursing Care for Pregnant Women With Preeclampsia: Literature Review Yenny Puspitasari; Budi Santoso; Nursalam Nursalam; Agus Sulistyono
STRADA : Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v9i2.390

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Incidence of preeclampsia cases is about 5-8% of all pregnancies. This research aims to analyze articles related the application of nursing model in pregnant with preeclampsia. The design of the research used is the literature review, articles collected using search engines such as EBSCO, Sciencedirect, Proquest and Elsevier. The article used was published in 2010-2019. Based on the article collected obtained the results that diagnose preeclampsia while pregnant can cause anxiety and fear increases during pregnancy. Because of this condition, individuals have increased blood pressure so as to develop a pathological nature. The role of nurses in providing therapy according to this model is to focus on human beings as a biopsicosocial creature as a unified and interconnected whole. Further studies are advised consider the effects on various variables by taking into account the random effects and changes in the model with the addition of contextual effects in the analysis.