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Respon Imunitas dan Badai Sitokin Severe Acute Respiratory Syndrome Corona Virus 2 : Literatur Review Lilin Rosyanti; Indriono Hadi
Jurnal Kesehatan Madani Medika (JKMM) Vol 11 No 2 (2020): Jurnal Kesehatan Madani Medika
Publisher : Sekolah Tinggi Ilmu Kesehatan Madani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (362.677 KB) | DOI: 10.36569/jmm.v11i2.122

Abstract

Penyakit menular Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2) merupakan ancaman global di seluruh dunia, di Indonesia pada desember 2020 terdapat kasus 617.820 positif, 505.836 sembuh, 18.819 meninggal, 63.698 suspek. Infeksi SARS-CoV-2 pada kasus yang parah akan menyebabkan kerusakan jaringan dan mengaktifkan serta merangsang respon imun. Protein RNA dan SARS-CoV-2, berinteraksi dan mengaktifkan reseptor sistem kekebalan secara berlebihan termasuk makrofag, granulosit termasuk produksi sitokin pro-inflamasi, aktivasi sel CD4 + T dan sel CD8 + T dengan tujuan mengendalikan replikasi virus, membatasi penyebaran virus, peradangan dan pembersihan. Namun respon imun yang terlalu aktif / berlebihan akan menyebabkan kerusakan jaringan dan peradangan yang dikenal dengan Badai sitokin. Lebih lanjut, jika sitokin proinflamasi terus diproduksi, hal itu akan memperburuk perjalanan penyakit dan prognosis serta kematian pada pasien dengan infeksi SARS-CoV-2.
Genetic Variation of I/D Enzyme Converting Angiotensin (ACE) with Athlete Muscle Resistance Indriono Hadi; Lilin Rosyanti
Health Notions Vol 3, No 3 (2019): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn30306

Abstract

Programmed physical exercise in athletes causes the cardiovascular system to be more efficient in pumping blood and carrying oxygen to muscles. Indicators of cardiovascular changes during exercise are: oxygen consumption, heart rate, stroke volume, differences in arterial and venous oxygen, blood pressure and blood flow. Some physical components that need to be considered for development include: VO2 max, muscle endurance, strength, flexibility, speed, stamina, agility, and explosive power. Some specific genes are identified as a muscle phenotype response to strength training, namely angiotensin-converting enzyme (ACE), which converts angiotensin I to angiotensin II. The insertion / deletion (I/D) polymorphism in this gene was found to play a role in variations in the activity of the ACE enzyme, in someone carrying a deletion allele (D) who had higher ACE enzyme activity. The research was carried out at the Organization of the Indonesian National Sports Committee (KONI), especially in South Sulawesi Bangkit athletes. The results showed a significant relationship between genetic variation in ACE gene (I/D) with muscle endurance (p-value 0.05). Likewise in sprints and endurance sports, there was no relationship with variations in the ACE gene (p-value >0.05). In conclusion, further research should be on athletes who win the Olympics or World Championships, with a single sports discipline, larger sample sizes and more diverse genetic variations, so that the ACE genotype can be explored and developed in athletes. Keywords: Athlete, Physical exercise, ACE gene, Genetic variation of I / D, Muscle endurance
The Effectiveness of Spiritual Qur’anic Emotional Freedom Technique (SQEFT) Intervence Against the Change of Brief Psychiatric Rating Scale (BPRS) on Patient with Schizophrenia Lilin Rosyanti; Indriono Hadi; Jayalangkara Tanra; Asadul Islam; Mochammad Hatta; Veny Hadju; Faizal Idrus; Kusman Ibrahim
Health Notions Vol 2, No 8 (2018): August
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (304.854 KB) | DOI: 10.33846/hn.v2i8.296

Abstract

Dimension of spiritual nursing demands the role of nurse in order to give holistic treatment, combine physical, psychological, social, and spiritual dimension. The psychospiritual intervention: SQEFT is intervention of psychospiritual combination that combines between spiritual Qur’anic therapy and psychological therapy of EFT, as additional spiritual intervention for patient with schizophrenia by not reducing any medical treatment program that the patient does. The objective of this research, in order to examine the influence of SQEFT Intervence Against The Change of BPRS on Patient with Schizophrenia. There were 7 mental patients skizoprenia participate of this research, who were diagnosed schizophrenia with psychiatry of DSM-IV-TR by psychiatric doctor with preliminary BPRS value scale in less than 60. The result test of Bonferroni showed that three groups had significant difference. There was a significant difference between non SQFET and SQEFT1, SQEFT2 with pvalue of 0.000. This difference showed that BPRS value moved lower significantly before being given SQEFT intervention, after being given SQEFT in stage 1 and SQEFT in stage 2. BPRS value that was lower showed psychological condition, schizophrenia patient’s cognitive condition which were better. Keywords: Psychospiritual intervention, SQEFT, BPRS, Nursing holistic, Schizophrenia
EKSPLORASI DAN EKSPRESI HASRAT SEKSUALITAS PADA PASIEN GAGAL GINJAL TERMINAL YANG MENJALANI HEMODIALISIS Lilin Rosyanti; Indriono Hadi; Kusman Ibrahim
Media Kesehatan Masyarakat Indonesia Vol. 13 No. 3: SEPTEMBER 2017
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30597/mkmi.v13i3.2673

Abstract

Penyakit Gagal Ginjal Terminal (GGT)) merupakan penyakit kronis dan terminal yang membutuhkan pengobatan Terapi Penggantian Ginjal (TPG). Salah satu jenis TPG adalah tindakan hemodialisis yang memengaruhi kehidupan seksual dan kualitas hidup pasien. Penelitian ini merupakan penelitian deskriptif kualitatif yang bertujuan mengeksplorasi ekspresi dan hasrat seksualitas pasien GGT yang menjalani hemodialisis di Rumah Sakit Hasan Sadikin Bandung. Jumlah peserta adalah 10 orang  dengan pasangan mereka, dengan usia 39-60 tahun. Analisis data yang digunakan adalah content analysis. Hasil penelitian ditemukan ada 3 kategori tema, yaitu: 1) perubahan dan keluhan fisik, tidak dapat ereksi lagi, maskulinitas tidak ada lagi. 2) Perubahan hasrat seksual, hasrat seksual tinggi tetapi kemampuan fisik menurun sehingga hasrat seksual menurun. 3) Perubahan ekspresi seksual dalam bentuk pelukan, ciuman, menyentuh, tetapi tidak dapat dapat menikmati lagi.
Tingkat Kecemasan Narapidana Wanita di Lapas Kendari dengan Kuesioner Taylor Manifest Anxiety Scale (TMAS) Indriono Hadi; Lilin Rosyanti; Nur Sri Afrianty
Health Information : Jurnal Penelitian Vol 10 No 2 (2018): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.618 KB) | DOI: 10.36990/hijp.v10i2.81

Abstract

When a woman is imprisoned, she will experience a lot of pressure. Prisons create feelings of fear and unpleasant feelings due to bad assumptions and pressures experienced such as beatings, torture, sexual harassment, poor health and very minimal facilities, besides that there is a stigma that will remain attached to someone when they are out of prison. The length of their sentence and isolation from the outside environment has a considerable psychological impact on the mental health of prisoners. The purpose of this study was to determine the anxiety level of female prisoners in prison using the Taylor Manifest Anxiety Scale (TMAS) Questionnaire. The sample in this study were all 30 female prisoners in prison. Using the descriptive approach method carried out in May-June 2016. The characteristics of respondents with the highest age were 26-35 years (50%), most of the respondents have formal education in SMA (53.33%), and have marriage (87%). The cause of imprisoned is drug usage (70%). The mean and deviation standard of the level of anxiety of female prisoners in prison are moderate anxiety (22.93 ± 3.58), severe anxiety (29.20 ± 5.52) and average mild anxiety (14 , 60 ± 1.14). This is importance for nurses and prison staff to give attention to the anxiety level of women in prison to prevent physical and psychological problems.
Eksplorasi Perubahan Fisik dan Gejolak Emosional pada Pasien Gagal Ginjal Kronis yang Menjalani Hemodialisis: Pendekatan Kualitatif Lilin Rosyanti; Indriono Hadi; Kusman Ibrahim
Health Information : Jurnal Penelitian Vol 10 No 2 (2018): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.883 KB) | DOI: 10.36990/hijp.v10i2.83

Abstract

Patients with terminal kidney failure report limitations and physical changes, psychological functions, and weaknesses that have a negative effect on health status and a decrease in survival. Progress in dialysis technology and disease management still raises many complaints both physically and psychologically by increasing the mortality rate of patients undergoing hemodialysis. In 2008, there were about 1.75 million patients worldwide who regularly received kidney replacement therapy in the form of dialysis, about 1.55 (89%) million underwent hemodialysis (HD) and around 197.000 (11%) used peritoneal dialysis (PD). This research explored the experience of hemodialysis patients with physical changes and emotional turmoil. This was a descriptive qualitative research that aimed to reveal broadly and deeply the causes and things that influenced the pattern of life behavior of patients from aspects of sexuality. The study found two categories of themes (1) physical changes and physical complaints: black facial skin, damaged teeth,body thin, body weak, and fatigue. (2) feeling and emotional turmoil: not accepting and fearing death, feeling helpless and useless, apologizing and suggesting that the couple remarry. The exploration experience of physical changes and emotional turmoil of hemodialysis patients were influenced by physical, physiological, psychological, social and spiritual aspects as well as values, cultures that exist in the lives of participants.
Mild Cognitive Impairment (MCI) pada Aspek Kognitif dan Tingkat Kemandirian Lansia dengan Mini-Mental State Examination (MMSE) Akhmad Akhmad; Sahmad Sahmad; Indriono Hadi; Lilin Rosyanti
Health Information : Jurnal Penelitian Vol 11 No 1 (2019): Januari-Juni
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.891 KB) | DOI: 10.36990/hijp.v11i1.105

Abstract

Aging reduces physical, psychological and social functioning. Cognitive impairment causes disabilities in daily functions and limits quality of life. In the elderly there is often a partial or total dependence on external assistance or care. The importance of a study to conduct a study on Mild Cognitive Impairment (MCI) on the Cognitive Aspects and the Level of Independence of the Elderly with a Mini-Mental State Examination (MMSE) measurement tool, in elderly people living in coastal areas who are part of the assisted blood of the nursing department. The type of research used is descriptive research, in August-December 2018 on the coast of Toronipa. The population in this study were all elderly who live in the Toronipa coastal area of ??Konawe Regency, an assessment instrument that functions to measure functional independence in self-care and mobility and is also used as a criterion in assessing functional ability for 10 minutes and assessing cognitive function in the areas of orientation, memory, attention and calculation, language construction and visuals. Patients score between 0 and 30 points, and cut-offs of 23/24 are usually used to indicate significant cognitive decline. Research result; Analysis on cognitive function: normal category 20 people (40.0%) while cognitive function disorders as many as 30 people (60.0%). The category of the independence level of the elderly, independent in carrying out daily activities as many as 48 people (96.0%), while those who experienced dependence amounted to 2 people (4.0%). The results of the analysis with the Chi Square test, the value of p = 0.510, meaning that the P value is greater than 0 , 05, so that there is no relationship between MCI from a cognitive aspect with the level of independence of the elderly in the coastal area of ??Toronipa.
Mekanisme yang Terlibat dalam Terapi Oksigen Hiperbarik: theoritical review hyperbaric oxygen therapy/HBOT Lilin Rosyanti; Indriono Hadi; Dian Yuniar Syanti Rayahu; Agus Bintara Birawida
Health Information : Jurnal Penelitian Vol 11 No 2 (2019): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (461.146 KB) | DOI: 10.36990/hijp.v11i2.144

Abstract

Terapi Oksigen Hiperbarik (HBOT) semakin sering digunakan di berbagai bidang medis, perawatan, dan praktik kesehatan. Menjadi intervensi penting dengan mekanisme tindakan yang tidak dipahami dengan baik. Terapi Oksigen Hiperbarik adalah salah satu metode pengobatan yang dilakukan dengan menyediakan 100% oksigen murni yang dihirup oleh pasien di ruangan khusus dengan udara bertekanan tinggi. Tekanan udara yang meningkat pada ruang Hiperbarik menyebabkan paru pasien menyerap lebih banyak oksigen daripada biasanya, yang dapat membantu menyembuhkan berbagai penyakit. Diharapkan adanya kajian ilmiah, ulasan dan diskusi tentang terapi heperbaric dan pencarian literatur tentang penggunaannya dapat bermanfaat bagi tim medis baik perawat, dokter, pekerja kesehatan lainnya dan masyarakat, sehingga mereka dapat meningkatkan pengetahuan, berdasarkan fisiologi, patologi, fisika, farmakologi, manfaat, indikasi dan perawatan tentang terapi hiperbarik sehingga dapat diterapkan dalam berbagai bidang yang diperlukan.
Efektivitas Terapi Spritual Shalat dan Dzikir terhadap Kontrol Diri Klien Penyalahgunaan Napza Akhmad Akhmad; Indriono Hadi; Askrening Askrening; Ismail Ismail
Health Information : Jurnal Penelitian Vol 11 No 2 (2019): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (450.234 KB) | DOI: 10.36990/hijp.v11i2.148

Abstract

Religion is one of the protective factors that provides positive results by preventing individuals from engaging in drug abuse. Religion and spirituality can inhibit addiction, and maintain self-control in drug abuse clients. Narcotics that are used continuously will result in a fairly high tolerance, and if the use is stopped it will cause with drawl or withdrawal syndrome. Healing is by means of medical and non-medical rehabilitation, non-medical rehabilitation, one of which is by means of spiritual healing techniques including prayer and dhikr, appearing as a valid Islamic spiritual healing method which is carried out by getting closer to the client to his spirituality and religion. The results of this study, on the pretest measurement results 16 respondents had negative self-control and 12 respondents had positive self-control, then after being given prayer and dzikir therapy treatment for two months, 26 respondents had positive self-control and 2 respondents had negative self-control. Mc Nemar statistical test p value <0.001 less than the value? 0.05, which means that there is an effect of the provision of prayer therapy accompanied by dhikr on client self-control of drug abuse.
Dampak Psikologis dalam Memberikan Perawatan dan Layanan Kesehatan Pasien COVID-19 pada Tenaga Profesional Kesehatan Lilin Rosyanti; Indriono Hadi
Health Information : Jurnal Penelitian Vol 12 No 1 (2020): Januari-Juni
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.vi.191

Abstract

Stress and anxiety are reactions to threatening and unpredictable situations such as in a coronavirus pandemic outbreak. Health workers are the most vulnerable to this. Stress-related reactions include changes in concentration, irritability, anxiety, insomnia, reduced productivity, and interpersonal conflict, in subsequent cases, they will experience more severe psychiatric conditions, separation from family, abnormal situation, increased exposure, increased exposure exposure, fear of transmission of COVID-19, feeling of failure in handling a poor prognosis, inadequate technical facilities, PPE, tools and equipment, to help treat patients. Health workers have difficulty maintaining physical and mental health conditions that are at risk of experiencing psychological disorders such as depression, anxiety, severe stress, and fatigue. Other risk factors identified are feelings of being unsupported, concerns about personal health, fear of bringing infections and transmitting them to family members or others, isolated, feeling uncertain, social stigmatization, excessive workload, and feeling insecure when providing care and health in COVID -19 patients.