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Iwan Dini
Dosen Jurusan Kimia Prodi Pendidikan Kimia FMIPA Universitas Negeri Makassar
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Journal : Hayyan Journal

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Caulerpin: Biosynthetic Significance and Cytotoxic Activity Against Artemia salina Leach Dini, Iwan
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i2.3261

Abstract

Caulerpin (1) is one of the bisindole alkaloid compounds isolated from the many macroalga species of the Halimeda and Caulerpa genera. The biosynthetic significance of 1 is suggested by the biotransformation of indole-3-acetic acid to indole-3-carboxaldehyde via tryptophan from the shikimate pathway. This compound has many biological activities reported and this time, the 1 were evaluated for their cytotoxicity in the brine shrimp assay against A. salina Leach. in vitro and showed moderate activity with IC50 value 81.28 µg/mL.
Co-Authors . DARMINTO Abda Abda Alimuddin Ali Army Auliah Asmawani, Nur Darminto . Diana Eka Pratiwi Eka Kartika, Andi Hardin Ilyas, Nita Magfirah Maryono Maryono Nisa, Sahratun Ramlawati Ramlawati Rismanto, Nur Azisah Ruslan, Zuhrah Adminira Sudding, Sudding Usman, Musawwir