Lelyana, Shelly
Departemen Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Kristen Maranatha, Bandung

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Efek Ekstrak Daun Oregano (Origanum vulgare) terhadap Plat Resin Akrilik Heat-Cured yang Dikontaminasi Candida albicans dan Streptococcus mutans Silvia Naliani; Shelly Lelyana; Henry Y. Mandalas; Jason F. Laurence; Vinna K. Sugiaman; Jane A. V. Wibisono; Dian Lesmana
e-GiGi Vol. 11 No. 1 (2023): e-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.v11i1.44461

Abstract

Abstract: Long-term use of dentures with poor cleaning can cause denture stomatitis mainly due to Candida albicans and Streptococcus mutans. Oregano leaf (Origanum vulgare) which contains a variety of active components is believed to be an alternative of denture cleansers. This study aimed to determine the effect of oregano leaf extract on heat-cured acrylic resin plates contaminated with C. albicans and S. mutans. There were 27 heat-cured acrylic plates contaminated and soaked for 10 minutes in nine treatment groups, as follows: oregano leaf extract of 50 mg/ml, 25 mg/ml, 12.5 mg/ml, 6.25 mg/ml, 3,125 mg /ml, 1,562 mg/ml, and 0,781 mg/ml, distilled water as the negative control, Polident denture cleanser fresh (positive control for C. albicans) and chlorhexidine gluconate 0,2% (positive control for S. mutans). The colony number of C. albicans and the inhibition zones of S. mutans were counted. The results showed that the lowest number of C. albicans colony and the largest inhibition zone for S. mutans were at the concentration of 50 mg/ml oregano leaf extract. In conclusion, there was an effect of oregano leaf extract on acrylic resin plates contaminated with Candida albicans and Streptococcus mutans. Keywords: acrylic resin; denture stomatitis; Origanum vulgare; Candida albicans; Streptococcus mutans   Abstrak: Penggunaan gigi tiruan secara terus menerus dalam jangka panjang dengan pembersihan yang buruk dapat menyebabkan denture stomatitis terutama oleh Candida albicans dan Strepto-coccus mutans. Daun oregano (Origanum vulgare) yang mengandung beragam komponen aktif diyakini dapat menjadi alternatif pembersih gigi tiruan. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak daun oregano terhadap plat resin akrilik heat-cured yang dikontaminasi jamur C. albicans dan S. mutans. Terdapat 27 plat akrilik heat-cured yang dikontaminasi dan dilakukan perendaman selama 10 menit dalam sembilan kelompok perlakuan yaitu, konsentrasi ekstrak daun oregano 50 mg/ml, 25 mg/ml, 12,5 mg/ml, 6,25 mg/ml, 3,125 mg/ml, 1,562 mg/ml, 0,781 mg/ml, akuades (kontrol negatif), Polident Denture Cleanser Fresh (kontrol positif C. albicans), dan chlorhexidine gluconate 0,2% (kon-trol positif S. mutans). Jumlah koloni C. albicans dan zona hambat S. mutans dihitung. Hasil penelitian menunjukkan jumlah koloni C. albicans terkecil dan zona hambat S. mutans terbesar pada konsentrasi ekstrak daun oregano 50 mg/ml. Simpulan penelitian ini ialah terdapat pengaruh ekstrak daun oregano terhadap plat resin akrilik yang dikontaminasi Candida albicans dan Streptococcus mutans. Kata kunci: resin akrilik; denture stomatitis; Origanum vulgare; Candida albicans; Streptococcus mutans
Polypharmacy and oral health-related quality of life in older adults: a systematic review Lelyana, Shelly; Agustina, Dewi; Hendrartini, Julita; Pramono, Dibyo
Padjadjaran Journal of Dentistry Vol 37, No 1 (2025): March 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no1.58618

Abstract

Introduction:: Patient-centered care requires medical personnel to address not only physical illnesses but also the psychosocial well-being of patients. older adultsOlder adults often have medically complex conditions, including one or more chronic diseases, requiring the use of multiple medications (polypharmacy). Polypharmacy is a common problem among older adults, with a reported prevalence of 30% to 80%. Many prescribed medications can lead to xerostomia and hyposalivation, which negatively impact the quality of life , including Oral Health-Related Quality of Life (OHRQoL). This systematic review aims to determine the impact of polypharmacy on OHRQoL in older adults and explore strategies to optimize OHRQoL in this population. Method: The dataset of articles concerning polypharmacy and OHRQoL in older adults was compiled from Google Scholar, PubMed, Semantic, and OpenAlex. The search encompassed publication from 2019 to 2024. Five articles were selected for in-depth analyses, and variations in methodologies used by the researchers in these selected studies were identified and considered. Results: Patients with polypharmacy hyposalivation exhibited significantly higher scores of the Summated Xerostomia Inventory questionnaire (SXI-PL) (8.60 ± 2.56) and the Oral Health Impact Profile-14 (OHIP-14sp) (16.0 ± 15.8). A statistically significant association was found between hyposalivation and both SXI-PL and OHIP-14sp scores (p < 0.05). Elderly individuals on continuous medication demonstrated increased odds of self-reported xerostomia (OR: 2.3; 95% CI: 1.19-4.67; P = 0.009). Conclusion: This study demonstrates an association between polypharmacy and decreased oral health-related quality of life (OHRQoL) in older adults.
Oral health management in hypertensive patients addressing coated tongue caused by antihypertensive medication use: a case report Tanumiharja, Marvin Jaya Setiadi; Tanumiharja, Leonardo Jaya Setiadi; Lelyana, Shelly; Kamil, Seno Muhammad
Padjadjaran Journal of Dentistry Vol 37, No 1 (2025): April 2025 (Supplements 1)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no1.59318

Abstract

Introduction: Hypertension is a chronic condition characterized by elevated blood pressure, often accompanied by symptoms such as headaches, epistaxis, and palpitations. Coated tongue is a clinical condition in which the tongue's surface develops a pseudomembrane due to accumulated debris, non-desquamated keratin cells, and microorganisms, such as bacteria and fungi.  This study aims to explore the potential relationship between hypertension and coated tongue, emphasizing the importance of oral hygiene in hypertensive patients. By examining a clinical case, the research highlights the role of tongue cleaning in managing coated tongue and improving oral health. Additionally, it underscores the need for patient education and adherence to proper oral hygiene practices to achieve better treatment outcomes.Case Report: A 49-year-old female patient presented to Sartika Asih Bhayangkara Hospital with complaints of persistent bad breath for one month. She reported white spots on her tongue causing discomfort but no pain. The patient reported brushing her teeth one to two times daily but had never cleaned her tongue. She had a history of hypertension and was one amlodipine therapy.Conclusion: Coated tongue in hypertensive patients can be managed through regular tongue cleaning after brushing. Effective communication, education, and patient cooperation are crucial for optimal treatment outcomes.