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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. E-Jurnal Medika Udayana Majalah Kedokteran Sriwijaya Nusantara Medical Science Journal Majalah Sainstekes The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Mandala of Health : A Scientific Journal
Bachtiar Murtala
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Nusantara Medical Science Journal

 1 
Gambaran Ultrasonografi Kelainan Endometrium pada Penderita Kanker Payudara yang Mendapat Terapi Hormonal di Rumah Sakit Wahidin Sudirohusodo Hijriah Thayyib; Mirna Muis; Bachtiar Murtala
Nusantara Medical Science Journal Volume 5 No. 2 Juli - Desember 2020
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v5i2.13408

Abstract

Pendahuluan: Penelitian ini bertujuan untuk menilai gambaran ultrasonografi kelainan endometrium pada penderita kanker payudara yang mendapat terapi hormonal di Rumah Sakit Wahidin Sudirohusodo. Metode:  Penelitian ini dilaksanakan di Rumah Sakit Umum Pemerintah Wahidin Sudirohusodo Makassar mulai bulan Januari sampai bulan Mei 2020. Sampel sebanyak 66 pasien yang telah mendapat terapi hormonal minimal 6 bulan berturut-turut dan dilakukan pemeriksaan ultrasonografi transvaginal. Metode analisis yang dilakukan adalah Uji Chi Square/Uji Fisher dan Uji T Independen. Hasil:   Pada penelitian ini, rentang usia terbanyak pasien kanker payudara adalah antara 41 – 50 tahun. Dari 66 pasien yang diteliti, terdapat 34 pasien yang premenopause dan 32 pasien yang menopause. Terdapat 46 pasien yang mendapat terapi Tamoxifen, 20 pasien yang mendapat terapi Aromatase inhibitor. Kesimpulan: Hasil penelitian menunjukkan tidak terdapat hubungan yang bermakna antara penebalan endometrium pada pemeriksaan ultrasonografi transvaginal dengan pemberian terapi hormonal pada penderita kanker payudara dengan nilai p=0,232. Terdapat hubungan bermakna antara status menstruasi dengan penebalan endometrium pada penderita kanker payudara yang mendapat terapi hormonal dengan nilai p=0,002. Terdapat hubungan bermakna antara Indeks Massa Tubuh (IMT) dengan penebalan endometrium pada penderita kanker payudara yang mendapat terapi hormonal dengan nilai p=0,037. Tidak terdapat hubungan bermakna antara penggunaan kontrasepsi hormonal terhadap penebalan endometrium dengan nilai p=0,946. Tidak terdapat hubungan yang bermakna antara nullipara dengan kejadian penebalan endometrium dengan nilai p=0,256
Pulmonary Tuberculosis CT-Scan Features and Sputum Smear in Tertiary Referral Hospital Nur Amelia Bachtiar; Sri Asriyani; Bachtiar Murtala; Irawaty Djaharuddin; Andi Alfian Zainuddin; Nikmatia Latief
Nusantara Medical Science Journal Volume 5 No. 2 Juli - Desember 2020
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v5i2.13489

Abstract

Introduction: Management of pulmonary tuberculosis (PTB) from primary and secondary health centers might affect the result of sputum acid-fast bacilli (AFB) smear and features of lung computed tomography scan (CT-scan) presented in tertiary hospitals. The study aims to investigate comparison between CT-scan features of PTB with sputum AFB smear in Wahidin Sudirohusodo Hospital as the top referral hospital in the Eastern part of Indonesia. Methods: This is a retrospective study of patients diagnosed as PTB by pulmonologist of nine months period. Patients with available CT-scan and sputum AFB smear results are included in the study. CT-scan features re-evaluated with RadiAnt DICOM viewer for standardized reading. The relationship between data obtained was analyzed with a chi-square test. Results: Sixty-one PTB patients were entered into the study. The three most common features found in CT were consolidation (93.4%) followed by Tree-in-bud (91.8%), and fibrosis calcification (85.2%). Relationship of CT features and sputum AFB smear was significant on cavity (p-value: 0.002) and pleural effusion (p-value: 0.020). However, unlike cavity (OR = 1.667), pleural effusion has opposite relationship (OR = 0.205) with sputum AFB smear. Conclusions: Pulmonary tuberculosis CT features seen in top referral hospitals can be very severe with consolidation and tree-in-buds as the most common features found in more than 90% of the cases. Feature of cavity may help radiologist to distinct highly active PTB with positive sputum AFB smear while presence of pleural effusion should raise the suspicion from pulmonologists to add further laboratory investigation.
Co-Authors Agustining Rahayu Andi Alfian Zainuddin Ariany Asnur Arifin Seweng Bachtiar, Nur Amelia Burhanuddin Bahar Cahyono Kaelan Fardah Akil HAM Akil Hijriah Thayyib Irawaty Djaharuddin Jimmy Tungka Junus Alkatiri Latief, Nikmatia M Adnan Mirna Muis Muhammad Ilyas Muhammad Yunus Amran,*,** Seung Pil Ban,** Ashari Bahar,* O-Ki Kwon** Muzakkir Amin Muzakkir Muzakkir N K Sungowati Nur Alam Nurlaily Idris Nu’man As Daud Rosita Kai Santa Jota Sri Asriyani Tajuddin Tjambolang Tatok Rudiharto Ulfiawaty Ulfiawaty Yohanes Irsandy Yuliawati Yuliawati