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Prevalence of Listeria spp. with PRS Genes in Fresh Vegetables from Traditional Markets A. Kaisar Adiwijaya Putra; Rizalinda Sjahril; Arif Santoso; Dianawaty Amiruddin; Andi Alfian Zainuddin; Firdaus Hamid
Biomedika Vol 13 No 2 (2020): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/biomedika.v13i2.842

Abstract

Listeriosis is a foodborne infectious disease caused by Listeria monocytogenes and is considered a serious health problem, due to the severity of symptoms and a high mortality rate in worldwide This study aims to identify and determine the prevalence of Listeria species through prs gene screening of fresh vegetables distributed in several markets of Makassar City. A total of 57 fresh vegetable samples were collected from February to May 2019 in four traditional markets Makassar. The isolates is examines to phenotypically and genotypically Vitek and Multiplex PCR with prs and lmo1030 primer. Phenotype analysis did not show the presence of Listeria species, but the results of genotypic was found 8 positive prs gene samples (14.03%), consisting of 31.2% long beans, 18.2% cabbage, and 9.1% cucumber and. All Listeria species found in this study is Listeria monocytogenes. This study also provide information and additional data that prs genes can be used as screening genotype for identify Listeria species in fresh vegetables.
The Influence of Fluoxetine Therapy Combination of Rational Emotive Behaviour Therapy Againts the Improvement of Depression Symptoms, Cognition Function and Improvement of Brain-Derived Neurotrophic Factors Serum Levels in Patients with Depressive Veraferial Muchtar; Erlyn Limoa; Nur Aeni M.A. Fattah; Andi Alfian Zainuddin; Ika Yustisia; Saidah Syamsuddin; Sonny Teddy Lisal
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15110

Abstract

Introduction: Depression is a health problem in the world that has affected more than 300 million peoplearound the globe. This health problem is characterized by feeling sad, depressed, irritability as well asdistortion of cognition such as self-criticism, feeling of guilt, feeling of worthlessness, lower self-confidence,pessimism and hopelessness where their manifestations may vary for each individual. Method: In this study,it compares the fluoxetine group combination of Rational Emotive Behavior Therapy (REBT) with thefluoxetine group in the treatment of reducing symptoms of depression and improving cognitive function.This research is an experimental research with pre-test and post-test control group design. The samplingtechnique was done by using consecutive sampling for each group. Results: From the results of the studyit was found that the mean of Hamilton Depression Rating Scale (HDRS), the Indonesian version of theMontreal Cognitive Assessment (MoCA-Ina) and Brain-Derived Neurotrophic Factor (BDNF) serum levelsin the samples given by both groups experienced statistically improvements. Conclusion: there is an effecton the provision of fluoxetine therapy combination of REBT compared to fluoxetine therapy alone inimproving depressive symptoms, cognitive function as well as increasing BDNF serum levels.
Correlation between Serum Calcium and Phosphate with Coronary Artery Calcium Scores on Cardiac MSCT Examination Rosita Kai; Bachtiar Murtala; Andi Alfian Zainuddin; Muzakkir Amin; Muhammad Ilyas
Saintika Medika Vol. 15 No. 2 (2019): December 2019
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol15.SMUMM2.9970

Abstract

Increased serum calcium and phosphate associated with cardiovascular disease in patients with chronic kidney disease, but research on the relationship between coronary artery calcium scores with serum calcium and phosphate in individuals with normal kidney function is lacking. We explore the relationship of serum calcium and phosphate levels with coronary atherosclerosis as assessed by cardiac Multislice Computed Tomography (MSCT) in individuals with normal kidney function. This study aims to assess the correlation of calcium level scores on cardiac MSCT examination with serum calcium and phosphate levels, and assess the association with risk factors for coronary heart disease. This study was a cross-sectional study of 40 subjects who underwent cardiac MSCT examination with normal kidney function, at RSUP Dr. Wahidin Sudirohusodo Makassar during the March-July 2019 period. The results showed an correlation between coronary artery calcium scores with calcium and serum phosphate (serum calcium r = 0.67, serum phosphate r = 0.53, p <0.05).
Korelasi Sudut Lumbosakral Berdasarkan MRI Lumbosakral dengan Oswestry Disability Index (ODI Score) pada Degenerative Disk Disease Yuliawati Yuliawati; Muhammad Ilyas; Bachtiar Murtala; Andi Alfian Zainuddin; Cahyono Kaelan; Mirna Muis
Majalah Sainstekes Vol 8, No 1 (2021): Juni 2021
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.728 KB) | DOI: 10.33476/ms.v8i1.1910

Abstract

Pengukuran sudut lumbosacral merupakan salah satu parameter dalam mengevaluasi kemungkinan etiologi dari nyeri punggung bawah yang disebabkan oleh degenerative disc disease. Oswestry Disability Index (ODI) Score digunakan untuk mengukur disabilitas pada nyeri punggung bawah. Penelitian ini bertujuan untuk mengetahui apakah ada korelasi antara sudut lumbosakral  berdasarkan MRI Lumbosakral dengan Oswestry Disability Index (ODI) Score pada degenerative disk disease. Penelitian ini menggunakan desain cross sectional yang dilaksanakan di Departemen Radiologi RS dr. Wahidin Sudirohusodo Makassar mulai bulan Mei sampai September 2020, didapatkan sampel sebanyak 67 pasien dengan keluhan nyeri punggung bawah dan telah mengisi kuisioner Oswestry Disability Index (ODI) Score serta menjalani pemeriksaan MRI lumbosacral. Pengukuran sudut lumbosacral dilakukan pada irisan mid sagital di work station MRI, derajat degenerative disc disease dinilai berdasarkan klasifikasi Pfirrmann. Metode  yang digunakan adalah uji korelasi Spearman dan Chi Square. Hasil penelitian menunjukkan adanya korelasi antara sudut lumbal lordosis (nilai p adalah 0,014), sudut sacral inclination (nilai p adalah 0,002), sudut sacral horizontal (nilai p adalah 0,034), umur  (nilai p kurang dari 0,0001) dengan degenerative disk disease. Tidak terdapat korelasi antara sudut lumbosacral disc (nilai p adalah 0,250), jenis kelamin (nilai p adalah 0,796), index massa tubuh (nilai p adalah 0,707) dengan degenerative disk disease. Adanya korelasi antara sudut lumbal lordosis (nilai p adalah 0,046), umur (nilai p kurang dari 0,0001), index massa tubuh (p kurang dari 0,0001) dengan ODI score. Tidak terdapat korelasi antara sudut lumbosacral disc (nilai p adalah 0,072), sudut sacral inclination (nilai p adalah 0,090), sudut sacral horizontal  (nilai p adalah 0,143),  jenis  kelamin  (nilai p adalah 0,337)  dengan  ODI   score. Adanya korelasi antara derajat degenerative disk disease dengan derajat ODI score (p kurang dari 0,0001)
KORELASI NILAI INTRAVESICAL PROSTATIC PROTRUSION DAN POST VOID RESIDUAL URINE MENGGUNAKAN PEMERIKSAAN ULTRASONOGRAFI TRANSABDOMINAL DENGAN SKOR INTERNATIONAL PROSTATE SYMPTOM PADA PASIEN PEMBESARAN PROSTAT JINAK Kiki Amelia Marlina; Nurlaily Idris; Nikmatia Latief; Andi Alfian Zainuddin; Syakri Syahrir; Mirna Muis
E-Jurnal Medika Udayana Vol 10 No 9 (2021): Vol 10 No 09(2021): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2021.V10.i9.P16

Abstract

ABSTRAK Kiki Amelia M. Korelasi Nilai Intravesical Prostatic Protrusion dan Post Void Residual Urine Menggunakan Pemeriksaan Ultrasonografi Transabdominal dengan Skor International Prostate Symptom pada Pasien Pembesaran Prostat Jinak (Dibimbing oleh Nurlaily Idris dan Nikmatia Latief). Penelitian ini bertujuan untuk menganalisis korelasi nilai intravesical prostatic protrusion (IPP) dan volume post void residual (PVR) urine menggunakan pemeriksaan ultrasonografi transabdominal dengan skor international prostate symptom (IPSS) pada pasien pembesaran prostat jinak. Penelitian ini dilaksanakan di Departemen Radiologi RSUP dr. Wahidin Sudirohusodo Makassar, mulai Maret hingga Oktober 2020. Jumlah sampel sebanyak 48 pasien. Metode yang digunakan adalah uji korelasi Spearman’s rho dan Chi-square. Hasil penelitian menunjukkan adanya korelasi antara volume prostat (p=0,0001, r=0,736) dengan skor international prostate symptom (IPSS), semakin besar volume prostat maka semakin tinggi skor IPSS. Terdapat korelasi antara derajat intravesical prostatic protrusion (IPP) (p=0,0001, r=0,675) dengan skor international prostate symptom (IPSS), semakin tinggi derajat IPP maka semakin tinggi pula skor IPSS. Tidak terdapat korelasi antara post void residu (PVR) urine (p=0,076, r=0,258) dengan skor international prostate symptom (IPSS), besarnya volume PVR tidak berkorelasi dengan skor IPSS. Tidak terdapat korelasi antara kalsifikasi prostat (p=0,493) dengan skor international prostate symptom (IPSS), dimana keberadaan kalsifikasi prostat tidak berkorelasi dengan skor IPSS. Kata kunci: Pembesaran prostat jinak, ultrasonografi transabdominal, intravesical prostatic protrusion, post void residual urine, kalsifikasi prostat, skor international prostate symptom
Comparison of Cardiac Size in Posteroanterior Chest X-Ray and Echocardiography Agustining Rahayu; Bachtiar Murtala; Sri Asriyani; Andi Alfian Zainuddin; Muzakkir Muzakkir; Nikmatia Latief
Majalah Kedokteran Sriwijaya Vol 51, No 4 (2019): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v51i4.10238

Abstract

Cardiac size is important to determine the presence of cardiac enlargement caused by left ventricular enlargement or right ventricular enlargement. Although echocardiography is considered to be the gold standard for cardiac enlargement, its availability is limited, expensive and requires trained experts. The posteroanterior (PA) chest X-ray (CXR) is the most common imaging used as a reliable alternative. The aim of this study was to compare cardiac size using cardiothoracic ratio (CTR) and transverse left cardiothoracic ratio (TL-CTR) in PA chest X-ray and echocardiography. This cross- sectional study involved 88 inclusion sample, aged 20-60 years. On the basis of provisional clinical diagnosis, the patients were divided three groups, consist of: (i) Group with normal cardiac size, (ii) Group with left ventricular enlargement (LVE) dan (iii) Group with right ventricular enlargement (RVE). All patients underwent PA CXR and M-Mode echocardiography examinations. The results of the two modalities were compared. CTR and TL-CTR, transverse diameter (TD) and transverse left (TL) in PA chest X-ray showed a strong positive correlation with total ventricular dimension (TVD) and left ventricular internal dimension (LVID) in echocardiography. CTR, TL-CTR, TD and TL in the PA chest X-ray are very good indicators for TVD and LVID in echocardiography. Chest X-ray is a reliable alternative for the diagnosis of cardiomegaly/cardiac enlargement in the absence of echocardiography. 
Pulmonary Tuberculosis CT-Scan Features and Sputum Smear in Tertiary Referral Hospital Nur Amelia Bachtiar; Sri Asriyani; Bachtiar Murtala; Irawaty Djaharuddin; Andi Alfian Zainuddin; Nikmatia Latief
Nusantara Medical Science Journal Volume 5 No. 2 Juli - Desember 2020
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v5i2.13489

Abstract

Introduction: Management of pulmonary tuberculosis (PTB) from primary and secondary health centers might affect the result of sputum acid-fast bacilli (AFB) smear and features of lung computed tomography scan (CT-scan) presented in tertiary hospitals. The study aims to investigate comparison between CT-scan features of PTB with sputum AFB smear in Wahidin Sudirohusodo Hospital as the top referral hospital in the Eastern part of Indonesia. Methods: This is a retrospective study of patients diagnosed as PTB by pulmonologist of nine months period. Patients with available CT-scan and sputum AFB smear results are included in the study. CT-scan features re-evaluated with RadiAnt DICOM viewer for standardized reading. The relationship between data obtained was analyzed with a chi-square test. Results: Sixty-one PTB patients were entered into the study. The three most common features found in CT were consolidation (93.4%) followed by Tree-in-bud (91.8%), and fibrosis calcification (85.2%). Relationship of CT features and sputum AFB smear was significant on cavity (p-value: 0.002) and pleural effusion (p-value: 0.020). However, unlike cavity (OR = 1.667), pleural effusion has opposite relationship (OR = 0.205) with sputum AFB smear. Conclusions: Pulmonary tuberculosis CT features seen in top referral hospitals can be very severe with consolidation and tree-in-buds as the most common features found in more than 90% of the cases. Feature of cavity may help radiologist to distinct highly active PTB with positive sputum AFB smear while presence of pleural effusion should raise the suspicion from pulmonologists to add further laboratory investigation.
Deteksi gen pneumolysin (ply) Streptococcus pneumoniae pada Sampel Klinis Usia Lanjut secara Kultur dan PCR Muthmainnah Muthmainnah; Mochammad Hatta; Muh. Nasrum Massi; Firdaus Hamid; Irawati Djaharuddin; Eddyman W Ferial; Andi Alfian Zainuddin; Mustika Hutabarat Sari
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 12 No 1 (2020): Jurnal Riset Kesehatan Poltekkes DepKes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.872 KB) | DOI: 10.34011/juriskesbdg.v12i1.850

Abstract

ABSTRACT Streptococcus pneumoniae, a gram-positive bacterium of normal flora but can be a pathogenic bacterium that causes pneumonia if the immune system declines. Community pneumonia ranks fourth and top ten diseases treated per year. Populations that are susceptible to pneumonia are children aged less than 2 years, old age. The Purpose aim to detect ply genes in sputum with suspected pneumonia in elderly as a virulence factor of S. pneumoniae by culture and PCR. This research method is a descriptive study to detect the virulence factor of the S. pneumoniae ply gene in the sputum of patients with suspected pneumonia in the elderly with the culture and PCR methods. Conventionally (culture method) obtained 1 sample from 56 positive samples of S. pneumoniae gram positive bacteria on the molecular method (PCR) there were 7 positive samples of S. pneumoniae bacteria from 56 samples. In detecting ply genes in sputum with suspected pneumonia in elderly as a virulence factor from S. pneumoniae bacteria were culturally detected 1 positive sample from 56 samples and by PCR method detected 7 positive samples from 56 samples. In detecting ply genes using culture and PCR it can be said that the PCR method is more accurate, fast and precise in detecting the S. pneumonia gene in sputum samples with suspected pneumonia in elderly.
ISOLASI METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) DARI NARES ANTERIOR PASIEN PRE-OPERASI ORTOPEDI Ilhamjaya, Andi Meutiah; Sjahril, Rizalinda; Johan, Muhammad Phetrus; Rasita, Yoeke Dewi; Mochammad Hatta; Andi Alfian Zainuddin; Patellongi, Ilhamjaya; Arden, Ferdinand
Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Vol 5 No 3 (2023): December
Publisher : Fakultas Kedokteran Universitas Alkhairaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31970/ma.v5i3.140

Abstract

Methicillin-Resistant Staphylococcus aureus (MRSA) dapat menyebabkan infeksi yang didapat di rumah sakit (HA-MRSA) atau yang didapat di masyarakat (CA-MRSA). Dengan dampak morbiditas dan mortalitas yang lebih tinggi. Dalam kondisi sumber daya yang terbatas, ketersediaan deteksi cepat masih belum memadai di beberapa fasilitas laboratorium di Indonesia. Seringkali, membutuhkan waktu lebih dari 48 hingga 72 jam untuk mengidentifikasi MRSA di laboratorium. Oleh karena itu, deteksi cepat menggunakan metode alternatif sangatdiperlukan untuk mempersingkat waktu yang diperlukan untuk mengidentifikasinya. Semakin cepat teridentifikasi saat skrining nares anterior pada pasien pre operasi ortopedi, maka semakin cepat pula tindakan pencegahan maupun pengendalian infeksi yang dapat dilakukan di Rumah Sakit. Penelitian ini merupakan penelitian observasional dengan desain cross sectional study. Pada penelitian ini dilakukan pengambilan sampel swab nares anterior pasien rencana bedah ortopedi di RSUP Dr. WahidinSudirohusodo dan RS Universitas Hasanuddin Makassar menggunakan medium transport Amies gel agar. Setelah itu dilakukan inokulasi langsung ke media CHROMOGENIC AGAR MRSA, hasil identifikasi dapat diketahui segera setelah 18-24 jam inkubasi pada media tersebut. Hasil penelitian menunjukkan dari 184 sampel yang diperoleh, proporsi temuan karier MRSA dari swab nares anterior pasien pre-operasi ortopedi di RSUP Wahidin Sudirohusodo Makassar adalah 66 pasien (38.4%), dan 8 pasien (4.6%) MSSA, sedangkan 98 pasien (57%)terdeteksi non aureus. Adapun karakteristik pasien yang mempunyai hubungan bermakna dengan temuan MRSA pada swab nares anterior pasien pre-operasi ortopedi yaitu karakteristik administrasi, riwayat rawat inap RS 3 bulan sebelumnya, dan riwayat pengunaan antibiotik 6 bulan terakhir (p value :0.001; 0.015; 0.002). Hasil penelitian disimpulkan bahwa pemanfaatan media CHROMOGENIC AGAR MRSA sebagai salah satu metodekultur untuk skrining MRSA pada nares anterior pasien pre-operasi ortopedi dapat menjadi pilihan yang efektifdan efisien dalam aplikasi klinis di lingkungan Rumah Sakit. Hal ini mengurangi penggunaan banyak bahan dilaboratorium, memudahkan dalam identifikasi langsung koloni oleh karena kekhasan koloni MRSA padamedia CHROMOGENIC AGAR, serta mempersingkat waktu yang diperlukan untuk mengidentifikasi MRSApada pasien, sehingga dapat memudahkan tindakan pencegahan dan pengendalian penyebaran MRSA dilingkungan Rumah Sakit, membantu mengurangi lama rawat inap pasien maupun mengurangi kemungkinanpenggunaan antibiotik jangka panjang pada pasien.
Geospatial analysis of type B and C hepatitis in South Sulawesi Rachmawarni Bachtiar, Rini; Andi Alfian Zainuddin; Rahmawati Minhajat1; Sri Jayanti
Nusantara Medical Science Journal Volume 9 Issue 1, January - June 2024
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Hepatitis C and B are two infectious diseases that increase distribution and high mortality and morbidity. Conditions that exacerbate the economic burden of these two viral hepatitis infections are complications of cirrhosis and gastrointestinal bleeding. This study sought to assess the risk levels of hepatitis C and B across various districts and cities in South Sulawesi. It involved identifying spatial clusters of affected individuals through an analytical model, employing Generalized Poisson Regression to evaluate the potential impacts of these viral infections. Methods:  The natural break method is a quantifiable technique for identifying value clusters indicative of data distribution and for detecting geographical illness clusters, using Global Moran’s I statistics. This research utilizes data from health insurance members diagnosed with hepatitis C and B between January 2020 and December 2022, including 24 districts and cities in South Sulawesi Province. Results:  According to the results of the Local Morans I analysis, there is no significant clustered hepatitis C and B in all districts and cities in South Sulawesi from 2020 until 2022. Conclusions: In South Sulawesi, the incidence of hepatitis C and B cases reported to National Social Health Insurance Administration Body (BPJS Kesehatan) appeared to manifest randomly or sporadically.