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All Journal Natural Science: Journal of Science and Technology Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Belitung Nursing Journal Nusantara Science and Technology Proceedings Journal of Global Pharma Technology Jurnal Pengabdian Farmasi dan Sains
Ingrid Faustine
Jurusan Farmasi,Fakultas MIPA, Universitas Tadulako, Palu, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing

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Clinical profile, treatment, and outcomes of patients with COVID-19 in a tertiary referral hospital in South Sumatera, Indonesia: A retrospective single-center study Deli Marteka; Amarila Malik; Ingrid Faustine; Nadia Farhanah Syafhan
Belitung Nursing Journal Vol. 8 No. 6 (2022): November - December
Publisher : Belitung Raya Foundation, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33546/bnj.2302

Abstract

Background: Although there are fewer COVID-19 cases in Indonesia, the pandemic is still ongoing. COVID-19 has a significant death rate in Indonesia, but lack of information on the effect of different clinical and demographic factors on COVID-19-related grimness and mortality in Indonesia. Objective: This study examined the clinical profile, treatment, and outcomes of patients with COVID-19 at Lahat Regency Hospital in South Sumatera, Indonesia, to find relevant markers that might be utilized to predict the prognosis of these patients. Methods: This was a retrospective single-center study of all medical record files of confirmed patients with COVID-19 admitted to Lahat Hospital from September 2020 to August 2021 (n = 285). Descriptive statistics, Chi-square, Mann-Whitney, Multiple Logistic Regression, and Cox's proportional hazards model were used for data analyses. Results: This study included 65 non-hospitalized and 220 hospitalized patients. Hospitalized patients were divided into dead and alive groups. The median age was lower in the non-hospitalized group without gender discrimination, and most hospitalized patients had comorbidities. Vital signs and clinical features were significantly different in hospitalized patients compared to non-hospitalized. The survival patients in the hospitalized group showed lower white blood cell (WBC), neutrophil percentages, and neutrophil-lymphocyte ratio (NLR) but higher lymphocyte and eosinophil. Non-survival patients had elevated alanine aminotransferase (ALT), blood urea nitrogen (BUN), creatinine, blood glucose, and potassium. The use of Favipiravir and Remdesivir was significant between the alive and dead groups. The mean hospital stay for all patients was 9.49 ± 4.77 days, while the median duration of hospital time was 10.73 ± 4.33 days in the survival group and 5.39 ± 3.78 days in the non-survival group. Multiple logistic regression analysis determined respiration rate, WBC, and BUN as predictors of survival. Conclusions: Age and comorbidities are significant elements impacting the seriousness of COVID-19. Abnormal signs in laboratory markers can be used as early warning and prognostic signs to prevent severity and death. Potential biomarkers at various degrees in patients with COVID-19 may also aid healthcare professionals in providing precision medicine and nursing.
The Socio-demographics and Clinical Characteristics and CD4 Profile of HIV/AIDS Patients Receiving First Line Antiretroviral Therapy at a Public Hospital in Palu Alwiyah Mukaddas; Ingrid Faustine; Pupuy Astarina Pilanto; Nurhayati Adnan
Nusantara Science and Technology Proceedings 1st International Conference on Health and Medicine
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2023.3509

Abstract

The Joint United Nations Program on HIV/AIDS (UNAIDS) set the pushful 90-90-90 target in 2015. It can be a difficult target to achieve without a comprehensive understanding of HIV epidemiology. This study aims to identify demographic and clinical characteristics and determine the difference between CD4 counts pre and post-antiretroviral (ARV) therapy in HIV patients of HIV/AIDS at a Public Hospital in Palu. A retrospective cross-sectional study of 27 HIV/AIDS patients was conducted between January 2011 and December 2015. Data were collected from medical records and electronic registries for HIV/AIDS patients. The study included 27 patients with complete data set from 230 patients, 63% productive age (25 - 44 years), 77,8% male, 85,2% were employed, 48,1% were well educated (from senior high school and equal), and 59,3% were married. The majority of patients acquired HIV through heterosexual transmission, 40,7%. At the time of the first clinic visit, 40,7% of patients had WHO stage III HIV infection. The rates of Candidiasis and TB coinfections were 22,2% and 18,5%, respectively. ZDV/3TC/NVP (74,1%) is the most commonly used antiretroviral combination. The baseline CD4+ cells count was < 350 cells/mm3 in 100% (n = 27) of patients, CD4+ median 126 cells/mm3. After Antiretroviral Therapy (ART) 6 months, two patients had a normal range CD4 500-1300 cells/mm3, CD4+ median 203 cells/mm3. There was a significant increase in CD4 count after ARV therapy (p=0,000; p<0,05). It suggests that ARV therapy can improve CD4 and immune recovery in HIV/AIDS patients.
PEMBERDAYAAN MASYARAKAT MELALUI REMAJA BEBAS NARKOBA Pitriani; Rizky, Muhammad; Aziza, Prisila; Jamaluddin; Faustine, Ingrid
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 3 No. 1 (2024): Oktober 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v3.i1.17468

Abstract

Drugs are an abbreviation of narcotics, psychotropics, and other active ingredients. Another term is NAPZA (Narcotics, psychotropics, and addictive substances). This activity aims to provide counseling or education in the form of socialization and education to adolescents, especially students of MTS Tosale so that they can know the dangers and effects of drug abuse and are expected to help create a younger generation with a more drug-free character. The Drug Socialization activity was implemented on October 26, 2023, at 08.00 and finished at the Tosale Village Office, Banawa Selatan District, Donggala Regency. The method used in this socialization activity is the lecture and documentation method. The results showed that 9 participants participated in the drug socialization activity. It can be concluded that the factors that cause adolescents to abuse drugs are family factors that pay less attention to their children and also environmental factors that can have a big influence. With education and religious education as the outermost wall to prevent drug abuse.
Profil Penggunaan Obat Antidotum Di Rumah Sakit Umum Daerah Undata Provinsi Sulawesi Tengah Periode 2016-2018: Profile of Using Antidotum at Undata General Hospital Central Sulawesi Province Periode of 2016-2018 Mukaddas, Alwiyah; Faustine, Ingrid; Ulti, Putri Hijjah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.867 KB) | DOI: 10.22487/j24428744.2019.v5.i2.13002

Abstract

Antidotes drug is indicated in intoxication or poisoning patients, in addition to the antidote drugs, it can also be used as an appropriate therapeutic indication of his own medicine. The high increasing number of the antidote drug used every year in inpatient instalation Undata hospital, for exmple atropine, N-acetylcysteine and pyridoxine (vitamin B6). Therefore, this study aims to determine the percentage of drug use of antidote category indicated as an antidote therapy in Undata hospitals Central Sulawesi Province period 2016-2018. This is a descriptive study with retrospective approach and using purposive sampling techniques.The results showed that the sample size was 75 patients, with the percentage of drug use as antidotes category in Undata Hospital Central Sulawesi province period 2016-2018, namely pyridoxine (vitamin B6) of 49.33%, N-acetylcysteine drug of 42.66% and the atropine drug of 8%. The use of antidotes drug category are indicated as an antidote to the poisoning therapy drugs obtained 0%. It can be concluded that there is no antidote drug category that used as an antidote therapy on patients with drug poisoning in inpatient instalation Undata hospital Central Sulawesi Province Period 2016-2018.
Correlation of Blood Glucose, Creatinine, and Uric Acid with Blood Pressure in Hypertension Patients : Korelasi Glukosa Darah, Kreatinin, dan Asam Urat dengan Tekanan Darah Pada Pasien Hipertensi Faustine, Ingrid; Yuliet, Yuliet; Hardani, Ririen; Hamdani, Silviana; Alfia, Dhara; Susilawati, Ni Made; Adisaputra, Arya Dibyo
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 1 (2025): (March 2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i1.17638

Abstract

Poorly controlled hypertension in hypertensive patients can increase the risk of cardiovascular disease in the future. Some of the triggering factors are impaired kidney function which is characterized by an increase in creatinine levels and other factors as well, namely an increase in uric acid levels and an increase in blood sugar levels. This study aims to analyze the correlation between blood glucose, creatinine, and uric acid levels in hypertensive patients in Central Sulawesi. With a cross-sectional design, this observational study involved 50 adult hypertensive patients in health facilities. Data were taken from laboratory examination results during visits and analyzed descriptively and analytically. The results showed that 60% of hypertensive patients were female, 62% had a family history of hypertension, and 80% still had blood pressure that was included in the criteria for hypertension. As many as 34% of hypertensive patients had abnormal blood glucose levels, 32% had abnormal creatinine levels, and 26% had abnormal uric acid levels. Still, no relationship was found between the three with blood pressure (p> 0.05). The correlation between blood glucose and blood pressure was -0.221, creatinine and blood pressure was -0.112, and uric acid and blood pressure was 0.132. It can be concluded that there is a positive correlation with a very weak correlation strength between uric acid levels and blood pressure in hypertensive patients.
Co-Authors Adisaputra, Arya Dibyo Alfia, Dhara Alwiyah Mukaddas Alwiyah Mukaddas Alwiyah Mukaddas Alwiyah Mukaddas Amarila Malik Arlinda Arlinda Aziza, Prisila Deli Marteka Fahrul Fahrul Fani Oktaviani Hamdani, Silviana Ida Nurlaelah Jamaluddin muhammad rizky, muhammad Nadia Farhanah Syafhan Ni Made Susilawati Nofriyanti Nofriyanti Nofriyanti Nofriyanti Nurhayati Adnan Pebrianti Pebrianti Pitriani Pupuy Astarina Pilanto Ririen Hardani Senfri Tandililing Ulti, Putri Hijjah Yuliet Yuliet Yusriadi Yusriadi