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All Journal PENA SAINS AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Journal of Research and Technology Prosiding Seminar Nasional Sains dan Teknologi Terapan Jurnal Tecnoscienza Abdi Masyarakat Jurnal Pengabdian Masyarakat Khatulistiwa Journal of Applied Sciences, Management and Engineering Technology (JASMET) Prosiding Seminar Nasional Teknologi Industri Berkelanjutan Journal of Industrial Process and Chemical Engineering (JOICHE) Science Get Journal
Eka Cahya Muliawati
Institut Teknologi Adhi Tama Surabaya
Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Physics Public Health Social Sciences Other

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Pemanfaatan Limbah Cair Tahu Sebagai Pembuatan Pupuk Organik Dengan Penambahan Bakteri Baik Pada Yakult, Gula, Dan Air Kelapa Muthia Lailyana; Eka Cahya Muliawati
Journal of Industrial Process and Chemical Engineering (JOICHE) Vol 2, No 2 (2022)
Publisher : Institut Teknologi Adhi Tama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31284/j.joiche.2022.v2i2.3859

Abstract

Tofu liquid waste is a white liquid with a thick texture derived from unused tofu production. Tofu liquid waste contains nitrogen, phosphorus, potassium, and protein, which are easily fermentable. It will pollute the environment and cause a bad smell if it is directly thrown away without prior processing. Therefore, tofu liquid waste was processed into organic liquid fertilizer. The purpose of this study was to determine the effect of fermentation time and sugar ratio on the levels of N, P, K The manufacture of liquid fertilizer involves a fermentation process by adding Yakult and EM-4 because both contain lactobacillus bacteria which can help the fermentation process. The sugar and coconut water were also added in a ratio of 1:0.075, 1:0.125, and 1:0.25. The process of liquid waste fermentation was carried out for 5 days, 10 days, 15 days, and 20 days. Fertilizers were tested using the Kjeldahl method for nitrogen (N) levels, spectrophotometry to determine phosphorus (P2O5) levels, and AAS (atomic absorption spectroscopy) for potassium (K2O) levels. The best levels of N, P, and K were produced from tofu waste with a fermentation process for 10 days by 0.662%, 1.133%, and 1.239%, respectively.
Desain Shell and Tube Heat Exchanger (STHE) Tipe Counter Current dengan Material Stainless Steel Eka Cahya Muliawati
Journal of Industrial Process and Chemical Engineering (JOICHE) Vol 2, No 2 (2022)
Publisher : Institut Teknologi Adhi Tama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31284/j.joiche.2022.v2i2.3860

Abstract

A heat exchanger or commonly referred to as a heat exchanger is a tool that is commonly used in the industrial world. The function of this tool is to cool down a fluid. There are various types of heat exchangers, including shell and tube. The purpose of this research is to design a heat exchanger that is good and correct and has a fairly high effectiveness in accordance with the existing heat exchanger design rules. The object of this research is a heat exchanger with a size of OD in, 16 BWG with stainless steel material which has a counter current type which is used to cool the type of air at a temperature of 80°C to 60°C with the help of an air type fluid also at a temperature of 60°C. 30°C. The effectiveness of the tool is quite large, namely 88.7%.
PEMANFAATAN SERABUT KELAPA SEBAGAI BIOSORBEN DALAM REMOVAL COD PADA LIMBAH CAIR INDUSTRI PEWARNA MAKANAN Dian Yanuarita Purwaningsih; Eka Cahya Muliawati
Journal of Industrial Process and Chemical Engineering (JOICHE) Vol 2, No 1 (2022)
Publisher : Institut Teknologi Adhi Tama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31284/j.joiche.2022.v2i1.3151

Abstract

The liquid waste of the food industry has recently increased. Therefore, when it is discharged into the waters, it will cause turbidity and can damage the ecosystem inside. One of the wastewater treatment techniques is absorption using biosorbents, one of which is made from coconut fiber to reduce the color intensity of the liquid waste. The purpose of this study was to determine the effects of the coconut fiber biosorbent on the color intensity, COD, and pH of the liquid waste of the food industry. In this research, the coconut fiber was delignified with a 2 M NaOH solution and then activated with a 3 N solution. The research variables consisted of the weight percentages of biosorbent by 1%, 2%, 3%, 4%, and 5%, and the contact time of 30 and 60 minutes with shaker stirring. Meanwhile, the most optimum results in COD removal happened at the addition of 4% for 60 minutes, from the initial COD of 1179 mg/L O2 to 780 mg/L O2 within the removal of 26.5%. The highest pH removal of 6.98 occurred in the variable addition of 1% for 30 minutes, whereas the lowest pH removal of 6.5
Review: Produksi Plastik Biodegradable Berbahan Dasar Tongkol Jagung sebagai Bahan Kemasan Qusnul Khotimah, Nimas; Muliawati, Eka Cahya; Afrimansyah, Mohammad Haris; Firnanda, Muhammad Yusron; Cantika, Putri Riau; Mubayyina, Al-; Larasati, Niken; Estiwardani, Riswanda
Journal of Research and Technology Vol. 11 No. 1 (2025): JRT Volume 11 No 1 Juni 2025
Publisher : 2477 - 6165

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55732/kb7j5j46

Abstract

Plastik umumnya terbuat dari bahan polimer sintetis hasil olahan minyak bumi. Karakteristik plastik sintetis yang sulit terurai menyebabkan penumpukan limbah dan pencemaran lingkungan yang serius. Salah satu solusi yang dikembangkan adalah penggunaan plastik biodegradable yang dapat terurai secara hayati. Review ini bertujuan untuk mengkaji metode dan hasil produksi plastik biodegradable berbahan dasar tongkol jagung. Salah satu kandungan utama tongkol jagung adalah serat selulosa, yang berpotensi dimanfaatkan sebagai polimer alami untuk pembuatan plastik ramah lingkungan. Metode pembuatan plastik biodegradable yang dikaji meliputi ekstraksi, casting, blending, komposit, dan metode lainnya yang disesuaikan dengan karakteristik material dan kebutuhan aplikasi. Review ini menganalisis 44 literatur terbitan tahun 2018 hingga 2024. Hasil terbaik ditemukan pada kombinasi bahan dasar tongkol jagung, sabut kelapa, dan CMC dengan plasticizer gliserol, yang menunjukkan hasil uji elongasi hingga 17,8 MPa, waktu biodegradasi tercepat selama 6 hari, dan daya serap air sebesar 26,02%. Nilai ini melampaui standar SNI untuk plastik biodegradable jenis termoplastik pati (TPS) yang memiliki kisaran kekuatan tarik 5–15 MPa.
Peningkatan Kualitas Produksi UKM Percetakan di Karangpilang Surabaya dan Krian Sidoarjo Kristanto, Titus; Muliawati, Eka Cahya; Arief, Rachman; Hidayat, Syaiful
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 2 No 1 (2018): Februari
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v2i1.1200

Abstract

 Mitra 1 (Purnama Advertising) is a printing business engaged in printing and graphic design, owned by Mr. Purnomo. Business location Purnama Advertising is very strategic close to the highway, due to many people skipped. Mitra 2 (Smart Jaya) owned by Mr. Hidayat handles a very simple print design. Smart Jaya business location is very strategic close to the school. The problems faced by Partners 1 and Partner 2 are constrained in the field of online marketing, due to the limited cost of the Partners. The purpose of the devotion activity is to develop an independent printing business and have a broad insight on print design and graphic design. The solutions offered from the devotion activities are providing printing machines and hot press machines, mentoring media marketing, production management and marketing training. The outcomes of the IbM program are scientific publications in ISSN Journals, national seminar publications, and online promotional media.    
Membran Polieugenol Tersulfonasi (PET) Sebagai Potensi Sel Bahan Bakar Metanol Langsung Muliawati, Eka Cahya; Yustia Wulandari Mirzayanti
Journal of Research and Technology Vol. 7 No. 2 (2021): JRT Volume 7 No 2 Des 2021
Publisher : 2477 - 6165

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55732/jrt.v7i2.478

Abstract

Nafion is a type of perfluorosulfonic acid membranes, are widely used in fuel cell technology and exhibit several disadvantages such as expensive, have a limited working temperature range and high methanol crossover. This study aims to produce an electrolyte new polymer membrane from polyeugenol sulfonated (PET) and a review of the membrane properties was carried out on the basis of Water Contact Angle (°), Water Uptake (%), Methanol Uptake (%), Swelling ratio (%), IEC (ion exchange capacity). Analysis of DMFC membrane performance has an optimal proton conductivity of 0.0009 S.cm-1 and methanol permeability of 23.5.10-7 cm2.s-1 with a PET composition of 27% (w/w).  
Integration of Photocatalysis and Membrane Technology as a Hybrid System for Microplastic Degradation in Wastewater Sri Rahayu Dwi Purnaningtyas; Mila Sari; Eka Cahya Muliawati; Afridon
Science Journal Get Press Vol 3 No 1 (2026): January, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i1.411

Abstract

Microplastic contamination in wastewater poses a serious threat to aquatic ecosystems and human health due to its persistence and limited removal by conventional treatment processes. This study evaluates a hybrid photocatalytic membrane reactor (PMR) integrating TiO₂-based photocatalysis with membrane filtration for the removal and degradation of polyethylene (PE), polypropylene (PP), and polyester (PET) microplastics. Photocatalytic membranes were fabricated via phase inversion using polyethersulfone (PES) and characterized by SEM, XRD, contact angle, porosity, and water flux measurements.TiO₂ incorporation significantly increased membrane hydrophilicity and permeability while maintaining the asymmetric structure and anatase crystallinity. The hybrid PMR achieved microplastic removal efficiencies above 99% for all polymers, outperforming membrane-only filtration and standalone photocatalysis. FTIR and SEM analyses confirmed oxidative polymer chain scission, while mineralization efficiencies reached 8.7%, 11.3%, and 18.9% for PE, PP, and PET, respectively. The degradation followed apparent first-order kinetics, with PET showing the highest rate constant. Hydroxyl radicals were identified as the dominant reactive species. The PMR also exhibited mitigated membrane fouling, stable performance over five cycles, and negligible TiO₂ leaching. The specific energy consumption ranged from 0.38 to 0.46 kWh m⁻³ with an estimated operational cost of USD 0.42–0.53 per m³. These findings demonstrate the technical and economic feasibility of the hybrid PMR for advanced microplastic treatment.
Exploration of CRISPR-Cas9 Gene Editing System Utilization for Targeted Induction of Apoptosis in Cancer Cells Resti Ariani; Eka Cahya Muliawati; Zola Efa Harnis
Science Journal Get Press Vol 3 No 1 (2026): January, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i1.436

Abstract

The CRISPR-Cas9 gene editing system represents a powerful approach for precision targeting of genetic determinants involved in cancer cell survival. This study evaluated the ability of CRISPR-Cas9 to induce apoptosis in cancer cells through targeted disruption of anti-apoptotic genes. Acute myeloid leukemia (HL-60 and KG-1) and anaplastic thyroid cancer (8505C and C643) cell lines were used to knockout BIRC5 (survivin) and MADD using specific single-guide RNAs. Efficient genome editing was achieved, with indel formation exceeding 50% across all models. Targeting BIRC5 and MADD significantly reduced cell viability to 39.8–54.6% of control levels and induced substantial apoptosis. Total apoptotic populations reached 52.8–60.1% following BIRC5 knockout and 45.3–50.6% following MADD knockout. Apoptosis induction was confirmed by caspase-3/7 activation, increased Sub-G1 accumulation, and cleavage of apoptosis-related proteins, indicating activation of the intrinsic apoptotic pathway.Notably, BIRC5 disruption consistently produced stronger pro-apoptotic effects than MADD across all cancer models. Overall, these findings highlight the therapeutic potential of CRISPR-Cas9–mediated targeting of anti-apoptotic genes as a promising strategy for precision oncology and for overcoming resistance to conventional cancer therapies.
The Application of CRISPR-Based Genetic Engineering for the Elimination of Harmful Inherited Diseases in Human Embryos Eka Cahya Muliawati
Science Journal Get Press Vol 3 No 1 (2026): January, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i1.446

Abstract

CRISPR-Cas9 genome editing offers a theoretical approach for preventing inherited diseases by correcting pathogenic mutations at the embryonic stage. This study presents a simulation-based assessment of CRISPR-Cas9–mediated correction of the pathogenic CAG repeat expansion in the Huntingtin (HTT) gene using a human embryo model. The analysis evaluated predicted editing efficiency, early developmental outcomes, unintended genomic modifications, and Huntingtin protein expression. Simulation results indicated that precise genetic correction was achieved in 42.7% of embryos, while a substantial proportion exhibited mosaic or partial editing. CRISPR-edited embryos showed a modest improvement in predicted blastocyst formation compared to untreated mutant controls but remained inferior to wild-type embryos. Unintended genomic alterations, including off-target edits and large deletions near the target site, were observed in a notable subset of embryos. Protein expression analysis suggested partial restoration of normal Huntingtin localization in successfully corrected embryos.These findings indicate that although CRISPR Cas9 mediated germline correction is theoretically feasible, persistent mosaicism and safety concerns currently limit its clinical applicability. Germline genome editing should therefore remain restricted to carefully regulated research settings.
EVALUATION OF BIOPLASTIC FROM BANANA PEELS: A SYSTEMATIC LITERATURE REVIEW Eka Cahya Muliawati; Dwiky Ari Rahmadi; David Yuliana Sari; Wahyu Wibisono Nur Aminnullah; Haris Fajar Kurniawan; Adinda Jamilatul Lestari; Ivan Maulana Alfandi
JURNAL PENA SAINS Vol 12, No 2 (2025): Jurnal Pena Sains
Publisher : Program Studi Pendidikan IPA, Fakultas Ilmu Pendidikan, Universitas Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/jps.v12i2.28881

Abstract

Bioplastics based on natural materials offer an innovative solution to reduce the negative impact of conventional plastics on the environment. This study evaluated bioplastics made from banana peels processed with various plasticizers, such as glycerol, chitosan, sorbitol, polylactic acid polymer, sodium metabisulfite, and tapioca starch. The focus was on mechanical properties, such as biodegradability, tensile strength, and elongation. Banana peels, with a starch content of 59%, proved ideal for bioplastics, with a degradation time of 4–84 days in soil. Bioplastics with 2% glycerol degraded in 4 days, while those with sodium metabisulfite degraded in 84 days. Glycerol increased flexibility but decreased tensile strength. The combination of 1.5% glycerol and tapioca starch produced the highest tensile strength of 66.39 MPa, while the highest elongation was 115.43% with 2% glycerol. This study highlights the potential of banana peel bioplastic as an environmentally friendly alternative, and further research is recommended to optimize the combination of plasticizers to make the bioplastic stronger, more elastic, and antibacterial by combining glycerol, sodium metabisulfite, and tapioca starch. These findings are important for the future development of sustainable and applicable bioplastics.
Co-Authors Adinda Jamilatul Lestari Adinda Jamilatul Lestari Adjie Sulaiman Adrian Felix Fauzi Rianto Afridon Afrimansyah, Mohammad Haris Aldrick, Samuel Evan Alfonsius Firman Amsalino Alimin Amirullah Andhika Darmana Salado Andy Rachman Ardhani, Yuniar Dwi Arinto Eka Prasetyo Raharjo Ayu Pupu Cantika, Putri Riau Chatarina Rista Widya Diana Danied Rifan Firmansach David Yuliana Sari David Yuliana Sari Denis Ryan Afrianto Devan Andriansyah Diajeng Pramesti Widodo Dian Yanuarita Purwaningsih Dwi Lulu Laurantini Dwiky Ari Rahmadi Dwiky Ari Rahmadi Estiwardani, Riswanda Fahrul Rosikin Firnanda, Muhammad Yusron Gasta Rahmadhan Halimatus Sadiyah Haris Fajar Kurniawan Haris Fajar Kurniawan Hasibur Rasyid Juniawan Hilmi Zainul Rizka Irsyad Al Fatah Ivan Maulana Alfandi Ivan Maulana Alfandi Joko Novianto Mila Sari Moch. Agil Soeharja Mubayyina, Al- Muchlis Dermawan Muhammad Alfaridzi Rusdiansyah Muhammad Muchlis Wijaya Muthia Lailyana Nanang Fakhrur Rozi Nely Handayani Niken Larasati Pratiwi Ratih Halimatus Sya'diah Qusnul Khotimah, Nimas Rachman Arief Rachman Arief Rachman Arief, Rachman Rani, Sefrilita Risqi Adikaning Resti Ariani Ria Sri Hapeni Setiya Eko Nurkaswoto Silvia Devi Eka Putri Sri Rahayu Dwi Purnaningtyas Syah Muhammad Syam Syaiful Hidayat Syaiful Hidayat, Syaiful Syaputra, Muhammad Rashid Titis Istiqomah Titus Kristanto Wachda Yuniar Rochmah Wahyu Santoso Wahyu Wibisono Nur Aminnullah Wahyu Wibisono Nur Aminnullah Yudistira Kusferianto Yustia Wulandari Mirzayanti Zola Efa Harnis