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All Journal Jurnal Kesehatan ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal farmasi UIN Alauddin Makassar
Faridha Yenny Nonci
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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PENENTUAN AKTIVITAS MINYAK DAUN NILAM (Pogostemon cablin Benth) TERHADAP PENYEMBUHAN LUKA SAYAT PADA MENCIT JANTAN (Mus musculus) Faridha Yenny Nonci; Afrisusnawati Rauf; Nur Afdhaliah
Jurnal Kesehatan Vol 10 No 2 (2017): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i2.4388

Abstract

Kerusakan jaringan tubuh dapat disebabkan oleh beberapa hal. Luka sayat merupakan suatu bentuk kerusakan atau kehilangan jaringan tubuh yang disebabkan oleh benda tajam. Aktivitas penyembuhan luka dapat ditemukan pada kandungan senyawa yang terdapat pada daun nilam yaitu minyak nilam yang memiliki kandungan senyawa patchouli alcohol, tanin, saponin dan α-bulnasen. Penelitian ini bertujuan untuk mengetahui aktivitas minyak daun nilam (Pogostemon  Cablin Benth) dalam penyembuhan luka sayat, mengetahui  konsentrasi yang paling baik dan bagaimana  perspektif Islam tentang pemanfaatan daun Nilam (Pogostemon cablin Benth) sebagai obat penyembuh luka sayat. Penelitian ini menggunakan metode penelitian  eksperimental laboratorium. Subjek penelitian adalah mencit yang dibagi menjadi  menjadi 7 kelompok  perlakuan. Kelompok I, II, III, IV dan V  adalah kelompok ekstrak daun Nilam (Pogostemon Cablin Benth) dengan konsentrasi  berturut-turut 10%, 20%, 30%, 40%, dan 50%, kelompok VI Betadin (Povidon Iodin 10%) sebagai kontrol positif dan kelompok VII Tween 80 sebagai kontrol negatif.  Pemberian dilakukan secara topikal dengan volume pemberian 1 ml. Hasil penelitian ini menunjukkan bahwa ekstrak minyak daun Nilam (Pogostemon Cablin Benth) pada konsentrasi 10%, 20%, 30%, 40%, dan 50% dapat menyembuhkan luka sayat pada mencit (Mus musculus) dan pada konsentrasi  50% menunjukkan aktivitas terbaik dalam penyembuhan luka sayat.
PENETAPAN KADAR TANIN TOTAL EKSTRAK BIJI JINTAN HITAM (Nigella sativa) SECARA SPEKTROFOTOMETRI UV-VIS Mukhriani Mukhriani; Faridha Yenny Nonci; Mumang Mumang
Jurnal Farmasi UIN Alauddin Makassar Vol 2 No 4 (2014): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v2i4.2162

Abstract

Researched about The Total Tannin Assay Extract of Black Cumin Seeds (Nigella sativa) with Ultraviolet-Visible Spectrophotometry. This research aims to determine the levels of total tannin extract of black cumin seeds (Nigella sativa). The method used is multilevel macerationusing n-hexane and ethanol 70%. Extracts were identified using FeCl3reagent and gelatin solution showed positive resultscontaining tannin onthe ethanol70%extract.The extracts thatpositive containing tannins diluted, added Folin Deanis reagent and saturated sodium carbonate, then read at 740  nm wavelength. Forming reaction was the oxidation reduction where tannin as reductant and Folin Denis as an oxidant. The results of oxidation will form a blue color that can be read at maximum wavelength. Based on the regression y = 0.004 x + 0.097 and 0.996 for determination coefficient, was gained an average of tannin levels in the ethanol extract of black cumin seeds (Nigella sativa) is 4, 13 %.
FORMULASI SEDIAAN LULUR KRIM AMPAS KEDELAI PUTIH DAN AMPAS KOPI ARABIKA Surya Ningsi; Faridha Yenny Nonci; Rifqiyati Sam
Jurnal Farmasi UIN Alauddin Makassar Vol 3 No 1 (2015): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v3i1.2173

Abstract

The  formulation  of  herbal  preparations  have  been  done  scrub  cream  white soybean dregs and arabica coffee dregs using a variation of the type of emulsifier, the nonionic surfactant (tween 80 and span 80) and a anionic surfactant (sodium lauryl sulfate). This study aims to determine the type of emulsifier which has good physical stability. Test stability scrub cream dosage is determined based on observations of organoleptic (color, smell and shape), creaming, viscosity, size of the dispersed drops, pH and phase inversion on the condition before and after accelerated storage at a temperature of 5oC and 35oC. Statistical analysis showed that the RAK emulsifier no significant differences on viscosity scrub cream before and after the storage accelerated and does not give any influence on organoleptic, the size of the dispersed drops, the pH before and after accelerated storage. The results of the study showed no creaming and inverse phase with all the scrub cream, so that all can be categorized as scrub cream with good stability.
ANALISIS KADAR FLAVONOID TOTAL PADA EKSTRAK DAUN SIRSAK (ANNONA MURICATA L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS. Mukhriani Mukhriani; Faridha Yenny Nonci; Siti Munawarah
Jurnal Farmasi UIN Alauddin Makassar Vol 3 No 2 (2015): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v3i2.2201

Abstract

A research on the determination of the total flavonoid content of 70% ethanol extract and n-hexane extract of leaves of soursop(Annona muricata L.). The purpose of this study was to determine levels of total flavonoids, contained in soursop leaf extract (Annona muricata L). Extraction of chemical constituents from leaves of soursop(Annonamuricata L.) done by maceration method using 70% ethanol. To determine the flavonoid compounds in the sample extracts, compound analysis is carried out using UV-Vis spectrophotometer. The results were obtained levels of total flavonoids of the soursop leaf (Annona muricata L). Of 70% ethanol extract was 2,82%. And n-hexane extract was 4,48 %. So the total flavonoid content of the extract of soursop leaf (Annona muricata L.) by 7.3% .
Efek Tabir Surya Ekstrak Daun Binahong (Anredera cordifolia) Nurshalati Tahar; Nurfajri Indriani; Faridha Yenny Nonci
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 2 No 1 (2019)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.68 KB) | DOI: 10.24252/djps.v2i1.6569

Abstract

Telah dilakukan penelitian tentang penentuan efek tabir surya ekstrak daun binahong [Anredera cordifolia (Ten.) Steenis]. Pengujian efek tabir surya dilakukan dengan menghitung nilai transmisi eritema (%Te), transmisi pigmentasi (%Tp), dan nilai SPF. Daun binahong diekstraksi dengan metode maserasi menggunakan pelarut etanol 96%. Pengujian efek berdasarkan serapan dan transmisi pada panjang gelombang UV yang diukur dengan spektrofotometer. Hasil pengujian nilai rata – rata persen transmisi eritema (%Te) pada konsentrasi (300 ppm, 350 ppm, 400 ppm, dan 450 ppm) berturut - turut adalah 31,52%; 23,90%; 20,27%; 14,71%. Sedangkan perhitungan nilai rata– rata persen transmisi pigmentasi (%Tp) yang diperoleh berturut-turut adalah 20,95%; 15,9%; 11,98%; 8,26%. Nilai rata-rata SPF berturut-turut adalah 4,36; 5,82; 7,44; 10,45. Hasil yang didapatkan menunjukkan bahwa Ekstrak Daun Binahong berefek sebagai tabir surya pada konsentrasi 450 ppm. Efek termasuk kategori fast tanning untuk proteksi eritema dan proteksi totalblock untuk proteksi pigmentasi.
Kemuning Leaves Extract Gel (Murraya panicula L.): A Study of Quality and Efficacy in Healing Burns Khairunnisa Hasbullah; Faridha Yenny Nonci; Muh. Ikhlas Arsul
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 1 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i1.13984

Abstract

This study aims to determine the activity of kemuning leaves extract in healing burns, and efficacy and quality of the extract in gel dosage form. The research was started with kemuning leaves extraction used maceration method with ethanol 96%, ethyl acetate and n-hexane as solvent. Each extract was activity tested for healing burn in rabbits. The extract that is most effective in wound healing then formulated into gel. The gel preparations were made in 3 variations of concentration, namely 5% (FI), 10% (FII), and 15% (FIII), with basis by carbopol 940 gel, triethanolamine, and methyl paraben. Then, gels were tested for efficacy and quality. The efficacy test follows the activity test procedure. Gel quality test includes organoleptic, pH, viscosity, dispersibility, and homogenity. The activity test showed that ethanol 96% extract, ethyl acetate and n-hexane healed burns in 13,3; 14,3; and 15,3 days, respectively. While the results of the gel efficacy test for FI, FII and FIII were 13,6; 11,6; and 9,6 days, respectively. In general, all gels have good qualities in every parameter, except the viscosity of FII and FIII which is slightly higher. Based on the results of the research, ethanol 96% extract was the most effective in healing burn. In addition, FIII gel has the best efficacy with good qualities except viscosity.
Studi Literatur Perbandingan Metode Uji Antioksidan pada Tanaman Kopi Robusta (Coffea robusta) Wahyuddin, Munifah; Faridha Yenny Nonci; Nur Azizah Syahrana; Nursasmita
Jurnal Farmasi UIN Alauddin Makassar Vol 12 No 1 (2024): Jurnal Farmasi Edisi Mei
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jfuinam.v12i1.37966

Abstract

Abstrak Antioksidan merupakan suatu senyawa yang dapat mencegah dan memperlambat kerusakan yang disebabkan oleh radikal bebas melalui penghambatan mekanisme oksidatif. Banyaknya metode uji aktivitas antioksidan dapat memberikan hasil uji yang beragam. Hal tersebut diakibatkan oleh adanya pengaruh dari struktur kimiawi antioksidan, sumber radikal bebas, dan sifat fisiko-kimia dari sampel. Penelitian ini bertujuan untuk mengetahui perbandingan metode antioksidan pada tanaman kopi robusta (Coffea robusta) berdasarkan kajian literatur. Dalam penelitian ini menggunakna metode kajian literatur, database dari Google Scholar, Science Direct dan Tylor & Francis. Hasil yang diperoleh adalah metode ABTS menunjukkan hasil aktivitas total antioksidan paling tinggi di mana nilai aktivitas antioksidannnya adalah 32.42±1.66 g trolox/100 g; 83,63%; 10.90±0.63 mg TE/g DW; 22.59±1.11 μ/ml; diikuti dengan metode Folin-Ciocalteu di mana nilai total aktivitas antioksidannya adalah 385±1 g GAE/ kg dan 1043 mg GAE/L dengan kandungan senyawa dalam tanaman kopi robusta (Coffea robusta) meliputi kafein, flavonoid, fenolik, dan asam klorogenat yang merupakan sumber antioksidan yang baik. Kata kunci: Coffea robusta, Antioksidan, Metode uji antioksidan
Co-Authors Afrisusnawati Rauf Khairunnisa Hasbullah Muh. Ikhlas Arsul Mukhriani, Mukhriani Mumang Mumang Nur Afdhaliah Nur Azizah Syahrana Nurfajri Indriani Nursasmita Nurshalati Tahar Nurul Muhlisah Maddeppungeng Rifqiyati Sam Siti Munawarah Surya Ningsi Wahyuddin, Munifah