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All Journal Indonesian Journal of Applied Sciences Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter International Journal of Integrated Health Sciences Jurnal Kesehatan Andalas Global Medical and Health Communication Majalah Kedokteran The Indonesian Biomedical Journal Andalas obstetrics and gynecology journal

Johanes C. Mose

Departemen Obstetri Dan Ginekologi, Fakultas Kedokteran, Universitas Padjadjaran, Bandung.

Author-ID : 2698780

Biochemistry, Genetics & Molecular Biology Dentistry Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

Published : 10 Documents Claim Missing Document

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Articles

Title

Kadar Calprotectin pada Bayi Kurang Bulan dan Respiratory Distress Syndrome Ali Usman; Abdurachman Sukadi; Johanes Cornelius Mose
Global Medical & Health Communication (GMHC) Vol 1, No 2 (2013)
Publisher : Universitas Islam Bandung

Calprotectin merupakan peptida antimikrob yang disimpan dalam leukosit sebagai molekul efektor dari respons imun innate. Terdapat infeksi intrauterin/intraamnion berhubungan dengan peningkatan calprotectin, defensin, dan bacterial permeability increasing protein (BPI) secara bermakna di dalam cairan amnion pada persalinan kurang bulan. Penelitian ini bertujuan untuk mengetahui kadar calprotectin pada bayi kurang bulan yang menderita dan tidak menderita respiratory distress syndrome (RDS). Penelitian observasional analitik dilakukan selama periode Maret 2010–Maret 2012 di RS Dr. Hasan Sadikin, RS Advent, RS Al Islam, RS Khusus Ibu dan Anak Kota Bandung, dan RS Ibu Anak Hermina Pasteur, diperoleh sampel sebanyak 60 bayi kurang bulan yang menderita dan tidak menderita RDS masing-masing sejumlah 30 orang. Cairan amnion diambil untuk pemeriksaan kadar calprotectin. Diagnosis RDS dibuat berdasarkan pemeriksaan fisis, skor Downe, dan foto toraks. Didapatkan nilai median kadar calprotectin pada kelompok bayi kurang bulan yang menderita RDS 3.302,6 sedangkan pada kelompok bayi yang tidak menderita RDS 7.908,85. Pada uji Mann-Whitney diperoleh Zm-w=3,063 (p=0,002). Cut-off point (COP) calprotectin >3.395,6 didapatkan jumlah RDS (+) 17 dan RDS (-) 4, sedangkan pada COP calprotectin >3.395,6 jumlah RDS (+) 13 dan RDS (-) 26. Dapat disimpulkan, kadar calprotectin pada bayi yang menderita RDS berbeda dibandingkan dengan kadar calprotectin pada bayi yang tidak menderita RDS. Kadar calprotectin dapat memprediksi kejadian RDS dengan sensitivitas 56,7%; spesifisitas 86,7%; dan akurasi 71,7%. CALPROTECTIN CONCENTRATIONS IN PRETERM NEONATES AND RESPIRATORY DISTRESS SYNDROMECalprotectin is antimicrobial peptides stored in leucocytes, that acts as effector molecules of the innate immune response. Intrauterine or intraamniotic infection was associated with a significant increase in amniotic fluid concentration of calprotectin, defencin and bacterial permeability increasing protein (BPI). The study aims to explore calprotectin concentrations at preterm neonates with and without respiratory distress syndrome. An observational analytic study was performed during March 2010-March 2012 in Dr. Hasan Sadikin, Advent, Al Islam, Bandung Mother and Child and Hermina Pasteur Hospitals. Subjects were 60 preterm neonates who divided in two groups, 30 neonates with and 30 neonates without RDS. Sixty samples of amniotic fluid were collected to examine calprotectin concentration. The diagnoses of RDS were made based on physical examination, Downe score and chest X-rays. Median value of calprotectin concentrations from preterm neonates with RDS were 3,302.6 and neonates without RDS were 7,908.85, with Mann-Whitney test Zm-w=3.063 (p=0.002). Cut off point (COP) of calprotectin 3,395.6 in RDS (+) were 17 and in RDS (-) were 4. Calprotectin in RDS COP >3,395.6 (+) were 13 and RDS (-) were 26. In conclusion, the concentration of calprotectin at RDS (+) is very low and significantly different with the one at RDS (-). The concentration of calprotectin can be used to predict the incidence of RDS with sensitivity 56.7%, specificity 86.7% and accuracy 71.7%.

The Effect of the BC-MK15 Birth Chair on the Labor Pain Intensity in Multipara Yetti Purnama; Johanes Cornelius Mose; Herry Herman
Global Medical & Health Communication (GMHC) Vol 6, No 3 (2018)
Publisher : Universitas Islam Bandung

Labor pain causes worry, anxiety, increases the secretion of the adrenaline, adrenocorticotropic hormone (ACTH), cortisol serum levels, catecholamines and the perception of pain. One method to decrease labor pain is through the mobilization and upright position during labor which is facilitated by the BC-MK15 birth chair to relax, decrease catecholamines, increase the release of β-endorphins and block the transmission of pain stimulus. This study aims was analyze the difference of the effect of using the BC-MK15 birth chair and the conventional bed on the intensity of labor pain in multipara. The design of this study was the posttest-only control group design in 60 samples of the first active phase of multipara at Public Health Centers Garuda, Ibrahim Adjie and Puter of Bandung city in April–May 2017. Each group consisted of 30 for treatment (using BC-MK15 birth chair) and control (using the conventional bed). Assessment of pain scores using the visual analogue scale (VAS) in cervical dilations of 4 cm (post 1), 7–9 cm (post 2) and 10 cm (post 3). The statistical test analysis uses the Mann-Whitney test and the chi-square test. There were significant differences among groups which are obtained by the treatment and control of post 2 and post 3 (p<0.05, RR=0.69 [0.531–0.896]). In conclusion, there is an effect of using the BC-MK15 birth chair and the conventional bed on the intensity of labor pain in multiparous mothers. PENGARUH KURSI PERSALINAN BC-MK15 TERHADAP INTENSITAS NYERI PERSALINAN PADA MULTIPARANyeri persalinan menimbulkan rasa khawatir, kecemasan, meningkatkan sekresi adrenalin, adrenocorticotropic hormone (ACTH), kadar kortisol serum, katekolamin, dan persepsi nyeri. Salah satu metode menurunkan nyeri persalinan adalah mobilisasi dan posisi tegak saat persalinan difasilitasi dengan kursi persalinan BC-MK15 sehingga menimbulkan relaksasi, menurunkan katekolamin, meningkatkan pelepasan β-endorfin, dan mengeblok transmisi stimulus nyeri. Penelitian ini bertujuan menganalisis perbedaan pengaruh penggunaan kursi persalinan BC-MK15 dan tempat tidur konvensional terhadap intensitas nyeri persalinan pada multipara. Desain penelitian eksperimen posttest-only control group design dengan jumlah sampel 60 multipara kala I fase aktif di Puskesmas Garuda, Ibrahim Adjie, dan Puter Kota Bandung pada bulan April–Mei 2017. Tiap-tiap kelompok berjumlah 30 untuk perlakuan (menggunakan kursi persalinan BC-MK15) dan kontrol (menggunakan tempat tidur konvensional). Penilaian skor nyeri menggunakan visual analogue scale (VAS) pada dilatasi serviks 4 cm (post 1), 7–9 cm (post 2), dan 10 cm (post 3). Pengujian statistik menggunakan analisis Uji Mann-Whitney dan uji chi-square. Didapatkan perbedaan bermakna antara kelompok perlakuan dan kontrol pada post 2 dan post 3 (p<0,05; RR=0,69 [0,531–0,896]). Simpulan, terdapat pengaruh penggunaan kursi persalinan BC-MK15 dan tempat tidur konvensional terhadap intensitas nyeri persalinan pada ibu multipara.

Co-Authors Abdurachman Sukadi Achmad Biben Adhi Pribadi Afriwardi Afriwardi Akhmad Yogi Pramatirta, Akhmad Yogi Ali Usman Aloysius Suryawan Assangga Guyansyah Bethy Suryawathy Hernowo Budi Handono Budi Handono BUDI SETIABUDIAWAN Fadil Oenzil Herry Herman Hirowati Ali Hudila Rifa Karmia Ida Parwati Jeffry Iman Gurnadi Masrul Netti Suharti Prima Nanda Fauziah RINI SUNDARI Vaulinne Basyir Yanti, Roza Sri Yanwirasti Yanwirasti Yetti Purnama Yusrawati Yusrawati

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