Article Per Year (5 Year)
p-Index From 2020 - 2025
2.255
P-Index
This Author published in this journals
All Journal Buletin Penelitian Tanaman Rempah dan Obat FITOFARMAKA: Jurnal Ilmiah Farmasi JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Ilmiah Farmako Bahari Buletin Penelitian Tanaman Rempah dan Obat Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan
Hindun, Siti
Fakultas MIPA Universitas Garut
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 13 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 13 Documents
Search

 1   2 
ACTIVITY TEST OF RED BETEL LEAF ETHANOL EXTRACT (Piper crocatum Ruiz & Pav) AS AN ACTIVE INGREDIENT IN SUNSCREEN PREPARATIONS Siti Hindun; Nopi Rantika; Aji Najihudin; Nurul Auliasari; Winna Khoerunisa
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1007

Abstract

Skin that is continuously exposed to sunlight can cause a reduction in the structure and elasticity of the skin and other bad effects, so it is necessary to have a skin protective agent, one of which is using sunscreen preparations. In the cosmetics sector, making products from natural ingredients is more profitable. They have a good tolerance for the skin because they do not cause severe irritation to sensitive skin. This research aims to determine the activity of red betel leaf ethanol extract as a sunscreen by looking at the SPF (Sun Protection Factor) value. The determination of the SPF value of red betel leaf ethanol extract was carried out in vitro using UV-Vis spectrophotometers at a wavelength range of 290 – 320 nm. Phytochemical testing is carried out to determine the content of chemical compounds that play a role in sunscreen activity. The research results show that the SPF values obtained from concentrations of 100, 200, 300, 400, 500, and 600 ppm, respectively, are 8.486 (extra-protection), 10,849 (maximum protection), 13,709 (maximum protection), 17.1 (ultra protection), 22 (ultra protection) and 25 (ultra protection). Based on the results of phytochemical tests, the ethanol extract of red betel leaves positively contains phenolics, flavonoids, alkaloids, tannins, saponins, steroids, and/or terpenoids. Keywords: Red betel leaves (Piper crocatum Ruiz &Pav), Sunscreen, SPF, In-Vitro, Ultra-protection
Potensi Tanaman Sebagai Pencerah Wajah Alami Rina Mustika; Siti Hindun; Nurul Auliasari
Jurnal Sains dan Kesehatan Vol. 2 No. 4 (2020): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i4.233

Abstract

Melanin is a pigment that gives human skin, hair and eye color. Excessive distribution of pigment malanin can cause skin problems such as hyperpigmentation. One of the principles of handling hyperpigmentation is to inhibit melanin synthesis which can be done by using a depigmentation agent (tyrosinase inhibitor) which has a mechanism of action to inhibit the tyrosinase enzyme. Inhibition of the tyrosinase enzyme can be done by measuring IC50 in a plant. IC50 is the concentration of an inhibitor needed to inhibit half of the enzyme activity. This review aims to compare the IC50 values ??of monophenolase activity and IC50 diphenolase activity in some plants that have tyrosinase inhibitory activity with invitro testing methods on L-tyrosine or L-DOPA substrates. The results of the study of several articles found that the plants that have the best potential to reward tyrosinase enzyme activity are sweet root extract (Glycyrrhiza glabra L.) with IC50 value 126.7548 µg / mL on the activity of diphenolase and extract of bark (Nauclea subdita) with IC50 value of 568.58 µg / mL on monofenolase activity.
Review: Perbandingan Beberapa Ekstrak Kulit Buah sebagai Anti-hiperpigmentasi: Review: Comparison of Fruit Skin Extract as Anti-hyperpigmentation Kianmaswati Nurdzul Allgisna; Siti Hindun; Nopi Rantika
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.403

Abstract

Hiperpigmentasi adalah istilah yang sering digunakan untuk menggambarkan kondisi di mana pigmentasi tidak rata di area kulit. Salah satu perawatan yang paling direkomendasikan untuk hiperpigmentasi adalah menggunakan hidrokuinon. Tetapi alternatif lain seperti bahan-bahan alami juga mendapatkan popularitas sebagai alternatif produk pencerah kulit yang baru meninjau studi klinis dengan menentukan perbandingan ekstrak kulit buah yang memiliki kemampuan terbaik untuk menghambat proses melanogenesis. Metode yang digunakan yaitu dengan pencarian data secara sistematis dengan database PubMed, NCBI dan SCOPUS yang dilakukan pada bulan Oktober 2020 yang menggunakan berbagai nama bahan, "IC50" dan "Anti - hiperpigmentasi". Diharapkan terbentuknya tinjauan literatur untuk mengungkapkan ekstrak mana yang memiliki kemampuan terbaik dalam menghambat proses melanogenesis. Ekstrak kulit jeruk, kulit apel, kulit pepaya, kulit pisang, dan terutama kulit delima yang memiliki aktivitas anti-tirosinase yang kuat dan dapat digunakan sebagai agen pemutih kulit.
Co-Authors Ajeng Siti Fauziyah Aji Najihudin Aji Najihudin Akmal Akmal Dani Sujana Dindin Fahrudin Fajar Fauzi Abdullah Framesti Frisma Sriarumtias Ghina Magfiroh Hanina Liddini Hanifa Hildan Nugraha Kianmaswati Nurdzul Allgisna NFN Noviyanti Nopi Rantika Nurmaya Sari Nurul Auliasari Rina Mustika Risha Amilia Pratiwi Sativa, Novriza Siva Hamdani Winna Khoerunisa