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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kedokteran Brawijaya Indonesian Journal of Urology Research Journal of Life Science Jurnal Farmasi Klinik Indonesia Majalah Kesehatan FKUB Heart Science Journal CRJIM (Clinical and Research Journal in Internal Medicine) Journal of Indonesia Vascular Access Deka in Medicine
Atma Gunawan
Laboratorium Ilmu Penyakit Dalam Rumah Sakit Umum Dr. Saiful Anwar Malang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Mortality Risk Factors in Continuous Ambulatory Peritoneal Dialysis Patients Widiaputro, Dandi; Gunawan, Atma; Rifai, Achmad
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.03

Abstract

Background: Chronic Kidney Disease (CKD) is a common kidney disorder among elderly individuals and is a leading cause of global mortality. Patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) are at high risk of complications and mortality. Therefore, analyzing risk factors for mortality in CAPD patients is crucial. Aim: To identify mortality risk factors in CAPD patients. Methods: This study was an observational retrospective study design. The sample consisted of CAPD patients at Saiful Anwar Hospital in Malang, with data collection from August 1st, 2019 to July 31st, 2023. Information collected included demographic data, medical history, and laboratory parameters. Data were analyzed using chi-square tests, t-tests, Kolmogorov-Smirnov tests, and multiple logistic regression to evaluate relationships, normality, risk factor effects, and the mortality rate of CAPD patients. Results: There were 377 subjects who met the inclusion criteria, consist of deceased (n=89) and alive (n=288) subjects. Older age significantly increased mortality risk with an odds ratio (OR) of 1.277 (95% CI: 1.260-1.294; p = 0.007). Diabetes mellitus increased mortality risk in CAPD patients, with an OR of 3.185 (95% CI: 1.427-7.105; p = 0.005). Heart failure increased mortality risk in CAPD patients, with an OR of 4.201 (95% CI: 2.170-8.133; p = 0.000). Decreased potassium levels increased mortality risk in CAPD patients, with an OR of 1.352 (95% CI: 1.020-1.792; p = 0.036). Conclusion: Older age, diabetes mellitus, heart failure, and decreased potassium levels increase mortality risk in CAPD patients.
Comparative Analysis of Cognitive Dysfunction in Chronic Kidney Disease Patients Undergoing Hemodialysis Versus Continuous Ambulatory Peritoneal Dialysis (CAPD) Sagala, Ida Meita; Rifai, Achmad; Gunawan, Atma
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.05

Abstract

Background: The increasing prevalence of impaired cognitive function in patients with chronic kidney disease (CKD) represents a significant global health concern. Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD) are two commonly employed treatment modalities for CKD; however, their effects on cognitive function in this patient population require further investigation. Aim: To compare the impairment of cognitive function between patients with CKD undergoing HD and those undergoing CAPD. Methods: This study employed a cross-sectional design utilizing observational methods conducted at Dr. Saiful Anwar Hospital from August 2024 to January 2025, involving 139 patients with CKD, comprising 50 patients undergoing CAPD and 89 patients undergoing HD. Cognitive function was assessed using the Montreal Cognitive Assessment-Indonesian version (MoCA-INA). Results: The prevalence of cognitive impairment was found to be 28.9% in patients undergoing HD and 40% in patients undergoing CAPD. The results of the comparative analysis indicated a significant difference between the cognitive scores of the CAPD group and those of the HD group, with a p-value of 0.008. Based on the comparison test of the degree of cognitive impairment, no significant differences were found between the HD and CAPD groups in the mild cognitive impairment (p = 0.471), moderate cognitive impairment (p = 0.317), and severe cognitive impairment (p = 0.480). Conclusion: There was a significant difference in the cognitive impairment scores between the CAPD group and the HD group.
HUBUNGAN ANTARA KOLONISASI KATETER DOUBLE LUMEN DENGAN KEJADIAN BAKTEREMIA PADA PASIEN HEMODIALISIS DI RSUD Dr. SAIFUL ANWAR MALANG Restyawan, Arie; Gunawan, Atma; Santosaningsih, Dewi
Majalah Kesehatan Vol. 0 No. 00 (2026): Article in Press
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Terapi hemodialisis dengan kateter double lumen sebagai akses vaskular utama, dapat meningkatkan risiko bakteremia terkait kateter, yang berdampak pada morbiditas, mortalitas, dan beban ekonomi. Penelitian ini bertujuan untuk mengkaji hubungan kolonisasi kateter double lumen hemodialisis dan kejadian bakteremia pada pasien hemodialisis, serta karakteristik pasien di RSUD Dr. Saiful Anwar Malang. Penelitian observasional analitik dengan desain cross-sectional dilakukan sejak April hingga Oktober 2024 di Unit Hemodialisis dan Laboratorium Mikrobiologi Klinik RSUD Dr. Saiful Anwar Malang. Semua pasien dewasa yang menjalani hemodialisis yang memenuhi kriteria inklusi dan eksklusi diikutsertakan dalam penelitian ini. Pasien dilakukan pemeriksaan kultur catheter tip dan kultur darah serta pencatatan data karakteristik pasien. Hasil penelitian ini menunjukkan 52,4% pasien mengalami bakteremia terkait kolonisasi kateter double lumen, namun tidak terdapat hubungan yang bermakna antara kolonisasi kateter double lumen dan kejadian bakteremia (p = 0,900). Staphylococcus aureus merupakan bakteri yang paling banyak ditemukan dari kultur catheter tip double lumen (40,9%) dan kultur darah (63,6%). Karakteristik pasien yang mengalami bakteremia terkait penggunaan kateter double lumen didominasi oleh pasien perempuan (63,7%), usia 36-45 tahun (36,3%), tingkat pendidikan SMA (72,7%), non-lupus nefritis (90,9%), non-diabetes mellitus (63,7%), tidak ada riwayat penggunaan steroid (90,9%), lokasi vena jugularis (90,9%), lama penggunaan kateter double lumen lebih dari 3 bulan (63,6%), dan frekuensi hemodialisis dua kali seminggu (90,9%). Disimpulkan bahwa tidak terdapat hubungan bermakna antara kolonisasi kateter double lumen dengan kejadian bakteremia. Penelitian dengan skala lebih besar disarankan untuk dilakukan di masa yang akan datang.  
Co-Authors ACHMAD RIFAI Anjarwani, Setyasih Cahayani, Putu Ayu Evie Dewi Santosaningsih Eko, Mudjiwijono Handaru Eldatarina, Helsa Engli, Katherina Etik Sulistyowati Fauzi Ahmad Muda Firmansah, Wahyu Fitriana, Dinar I. Hamam Hadi Handono Kalim Hani Susianti Haryanto, Ahmad Farid Haryanto, Dheni Indra Prasetya Kurnianingsih, Novi Kusworini Handono Maharani, Revina Mazen, Mazen Nurudinulloh, Akhmad Isna Rahardja, Ketut Restyawan, Arie Retty Ratnawati Sagala, Ida Meita Susetyowati Suwito, Heru Tamaulina Br Sembiring Tinny Endang Hernowati Titisari, Nurina Wattimury, Rosmince Widiaputro, Dandi Widito, Sasmojo Wiwi Jaya Yuliana Salman Yunita, Ema P.