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Risk factors associated with the incidence of Arteriovenous (AV) shunt stenosis in Chronic Kidney Disease (CKD) patients on hemodialysis Gunawan, Atma; Rifai, Achmad; Kurnianingsih, Novi; Haryanto, Ahmad Farid
Journal of Indonesia Vascular Access Vol. 5 No. 2 (2025): Available online : 1 December 2025
Publisher : Indonesian Vascular Access Association (IVAA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jinava.v5i2.84

Abstract

Background: Arteriovenous (AV) shunt stenosis is a significant complication in chronic kidney disease (CKD) patients undergoing hemodialysis with AV shunt access. The risk factors associated with this event are still not fully understood. This study aims to identify factors associated with the incidence of AV shunt stenosis in CKD patients undergoing dialysis. Methods: A cross-sectional study was conducted involving 236 patients undergoing hemodialysis at Dr. Saiful Anwar General Hospital, Malang. Risk factors analyzed included age, gender, diabetes mellitus, hypertension, obesity, and AV shunt location. Results: Bivariate analysis using the Chi-square test showed significant associations between stenosis and age (p=0.020), gender (p=0.001), diabetes mellitus (p=0.001), and hypertension (p=0.031). However, obesity (p=0.608) and AV shunt location (p=0.552) were not significantly associated. Logistic regression analysis indicated that diabetes mellitus increased the risk of AV shunt stenosis by 2.46 times (95% CI: 1.42-4.26), hypertension by 2.05 times (95% CI: 1.06-3.96), and age above 60 years by 1.93 times (95% CI: 1.10-3.37) Conclusion: Diabetes mellitus, hypertension, advanced age, and smoking are key risk factors for AV shunt stenosis in CKD patients undergoing dialysis
Mortality Risk Factors in Continuous Ambulatory Peritoneal Dialysis Patients Widiaputro, Dandi; Gunawan, Atma; Rifai, Achmad
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.03

Abstract

Background: Chronic Kidney Disease (CKD) is a common kidney disorder among elderly individuals and is a leading cause of global mortality. Patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) are at high risk of complications and mortality. Therefore, analyzing risk factors for mortality in CAPD patients is crucial. Aim: To identify mortality risk factors in CAPD patients. Methods: This study was an observational retrospective study design. The sample consisted of CAPD patients at Saiful Anwar Hospital in Malang, with data collection from August 1st, 2019 to July 31st, 2023. Information collected included demographic data, medical history, and laboratory parameters. Data were analyzed using chi-square tests, t-tests, Kolmogorov-Smirnov tests, and multiple logistic regression to evaluate relationships, normality, risk factor effects, and the mortality rate of CAPD patients. Results: There were 377 subjects who met the inclusion criteria, consist of deceased (n=89) and alive (n=288) subjects. Older age significantly increased mortality risk with an odds ratio (OR) of 1.277 (95% CI: 1.260-1.294; p = 0.007). Diabetes mellitus increased mortality risk in CAPD patients, with an OR of 3.185 (95% CI: 1.427-7.105; p = 0.005). Heart failure increased mortality risk in CAPD patients, with an OR of 4.201 (95% CI: 2.170-8.133; p = 0.000). Decreased potassium levels increased mortality risk in CAPD patients, with an OR of 1.352 (95% CI: 1.020-1.792; p = 0.036). Conclusion: Older age, diabetes mellitus, heart failure, and decreased potassium levels increase mortality risk in CAPD patients.
Comparative Analysis of Cognitive Dysfunction in Chronic Kidney Disease Patients Undergoing Hemodialysis Versus Continuous Ambulatory Peritoneal Dialysis (CAPD) Sagala, Ida Meita; Rifai, Achmad; Gunawan, Atma
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.05

Abstract

Background: The increasing prevalence of impaired cognitive function in patients with chronic kidney disease (CKD) represents a significant global health concern. Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD) are two commonly employed treatment modalities for CKD; however, their effects on cognitive function in this patient population require further investigation. Aim: To compare the impairment of cognitive function between patients with CKD undergoing HD and those undergoing CAPD. Methods: This study employed a cross-sectional design utilizing observational methods conducted at Dr. Saiful Anwar Hospital from August 2024 to January 2025, involving 139 patients with CKD, comprising 50 patients undergoing CAPD and 89 patients undergoing HD. Cognitive function was assessed using the Montreal Cognitive Assessment-Indonesian version (MoCA-INA). Results: The prevalence of cognitive impairment was found to be 28.9% in patients undergoing HD and 40% in patients undergoing CAPD. The results of the comparative analysis indicated a significant difference between the cognitive scores of the CAPD group and those of the HD group, with a p-value of 0.008. Based on the comparison test of the degree of cognitive impairment, no significant differences were found between the HD and CAPD groups in the mild cognitive impairment (p = 0.471), moderate cognitive impairment (p = 0.317), and severe cognitive impairment (p = 0.480). Conclusion: There was a significant difference in the cognitive impairment scores between the CAPD group and the HD group.