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Jejuno-Ileal Atresia: Faktor-Faktor yang Mempengaruhi Mortalitas Sugianto Prajitno
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 4 No. 4 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v4i4.5740

Abstract

Jejuno-ileal atresia (JIA) is one of the leading causes of neonatal bowel obstruction. Over the last decade, mortality has decreased, with recent studies reporting a mortality rate of 11%. This study aimed to evaluate factors affecting mortality among patients with JIA. A retrospective cross-sectional study was conducted on all JIA patients admitted between January 2019 and December 2024. Demographic variables including gestational age (prematurity ≤36 weeks), birth weight (low birth weight/LBW ≤2,500 grams), sepsis, and location of atresia were analyzed in relation to mortality using Chi-square and logistic regression tests. Thirty neonates (15 boys and 15 girls) were included. Primary anastomosis was performed in 18 patients (60%), while 12 patients (40%) underwent stoma formation. The mean time to achieve full enteral feeding was 10.23 days (range 6–35 days). Mortality occurred in 17 of 30 patients (56.7%), of which 9 were premature, 11 were LBW, and 13 had sepsis. Jejunal atresia was found in 8 patients with 5 deaths, while ileal atresia was present in 22 patients with 12 deaths. Sepsis showed a significant association with mortality (p= 0.030), and combined LBW and prematurity were also significantly associated (p= 0.010). Multivariate analysis revealed that LBW and prematurity were independent predictors of mortality. In conclusion, while sepsis was significantly associated with mortality in univariate analysis, LBW and prematurity emerged as significant predictors in multivariate analysis.
HUBUNGAN UKURAN DEFEK OMPHALOCELE TERHADAP KELAINAN KONGENITAL PENYERTA Sugianto, Prajitno
JURNAL KEDOKTERAN Vol. 5 No. 2 (2020)
Publisher : Fakultas Kedokteran Universitas Islam Al-Azhar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36679/kedokteran.v5i2.222

Abstract

Background: Omphalocele is often associated with the presence of other congenital anomalies. One study says that a small of defect omphalocele is often accompanied by intestinal disorders and have a better prognosis. Based on this study the researcher wants to review the relationship between the size of omphalocele defect and the presence of associated congenital anomaly in Hasan Sadikin Hospital. Methods: This is a retrospective cross-sectional study. All patient with omphalocele between January 2007 – March 2012 were included in this study. Data collected were patient demographics, size of omphalocele defect and congenital anomalies identified. In this study, patients were designated as those with small (4 cm and less) or large (greater than 4 cm) defect omphaloceles. This study analyzed correlation between size of defect with associated anomaly using Fisher exact test and p < 0.05 is considered to be significant. Results: There were 52 omphalocele cases (24 girls, 28 boys), median birth weight 2710gr (range 1300gr–4000gr). Twenty seven patients were classified as small defect, with 25 classified as large defect. Anomaly found in the small defect groups consists of facial anomaly (7%); cardiac anomaly (7%); intestinal disorder (22%,P=0,02) include patent omphalomesentericus duct, anorectal malformation and cloaca extrophi; limb anomaly (7%). Meanwhile, anomalies identified in the large defect group consist of facial anomaly (8%); cardac defect (32%) include dextrocardi and tetralogi Fallot; limb anomaly (16%).In this study, cardiac defects was significantly higher in the large defect group, meanwhile intestinal diorder is statistically significant in small defect groups. Conclusion: Small defect omphalocele correlates with an increased prevalence of associated gastrointestinal anomalies and a lower prevalence of cardiac anomalies.