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All Journal Bioscience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA JSFK (Jurnal Sains Farmasi & Klinis) Buletin Ilmiah Nagari Membangun Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Dita Permatasari
Fakultas Farmasi Universitas Andalas
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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The Sub Acute Toxicity Study of Purified Gambir (Uncaria gambir Roxb.) to Liver Histology and its Reversibility on Rats Dita Permatasari; Indri Oktavia; Armenia Nazar; Almahdy Ahmadin
Bioscience Vol 5, No 1 (2021): Biology
Publisher : UNIVERSITAS NEGERI PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/0202151111642-0-00

Abstract

Purified gambir proved to have many pharmacological activities and has the potential to be developed into standardized herbal medicines. This study was conducted to determine the safety of purified gambir to the liver histology. A total of 30 female white rats were used which divided into 4 groups: one control group and 3 test groups treated with purified gambir at doses of 5, 10 and 20 mg/kgbw orally for 14 days respectively. On the scheduled days, three animals from each group were killed for liver histological examination. The degree of liver damage and liver organ ratio in this study where were measured. The reversibility of liver damage was observed from the change in the value of the damage degree and liver organ ratio after the administration of gambir was stopped. Data were analyzed using two-way ANOVA followed by Duncan (significance were taken at p<0.05). The administration of purified gambir in rats for 14 days at tested groups caused significant damage to liver tissue (p<0.05). In this situation, the degree of tissue damage increased and the liver organ ratio decreased in all tested groups. After the administration was stopped, the degree of liver damage is decreased insignificantly, meanwhile the liver organ ratio is significantly increased.
Evaluasi Rasionalitas Penggunaan Obat Neuroprotektif pada Pasien Stroke Iskemik di Rumah Sakit Stroke Nasional Bukittinggi Dita Permatasari; Dian Ayu Juwita; Rahmi Yosmar; Julio Fajar Rahmat Illahi
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 8 No. 2 (2021): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v8i22021.162-167

Abstract

Pendahuluan: Stroke iskemik disebabkan oleh pembentukan trombus lokal atau emboli yang terjadi pada arteri serebral. Hal tersebut menyebabkan kurangnya aliran darah sehingga oksigen yang dibutuhkan oleh jaringan otak juga berkurang. Angka kejadian stroke iskemik mencapai 87% yang merupakan angka tertinggi dari seluruh kasus stroke lainnya. Obat neuroprotektif termasuk salah satu terapi yang ditujukan untuk mengurangi kerusakan saraf yang disebabkan oleh serangan stroke iskemik. Tujuan: Tujuan penelitian ini untuk mengetahui karakteristik demografi pasien stroke iskemik, pola penggunaan obat dan rasionalitas obat neuroprotektif pada pasien stroke iskemik. Metode: Metode penelitian ini adalah observasional yang diambil dari data rekam medik instalasi rawat inap (n = 280) tahun 2019 secara retrospektif. Data yang diperolah akan dibandingkan terhadap standar pengobatan yang telah ditetapkan. Hasil: Hasil penelitian menunjukan bahwa pasien stroke iskemik terbanyak yaitu laki-laki sebesar 63,2% dengan rentang usia 55 - 64 tahun sebesar 39%. Persentase tertinggi dari status pendidikan terakhir yaitu SLTA mencapai 47,1%. diikuti dengan status pekerjaan terbanyak yaitu IRT sebesar 28,2%. Penggunaan obat neuroprotektif paling banyak digunakan adalah sitikolin sebesar 53,2% dengan rute pemberian secara intravena mencapai 51,8%. Evaluasi rasionalitas penggunaan obat neuroprotektif pada rumah sakit tersebut antara lain, tepat indikasi 100%, tepat pasien 99,3%, tepat obat 100%, tepat dosis 97,9%, dan tepat frekuensi pemberian obat 99,3%. Kesimpulan: Kejadian terapi tidak rasional masih ditemukan pada 8 orang pasien tersebar pada indikator tepat pasien, tepat dosis dan tepat frekuensi pemberian obat.
Application of Home Medication Review (HMR) on Patient Adherence in Type 2 Diabetes Mellitus (T2DM) Blood Sugar Management Yelly Oktavia Sari; Dita Permatasari; Wilnando Mariza; Najmiatul Fitria; Resa Lailiani
Jurnal Sains Farmasi & Klinis Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.160-167.2022

Abstract

Non-adherence of type 2 diabetes mellitus (T2DM) patients in treatment will impact expected clinical outcomes, risk of complications, and poor quality of life. Home medication review (HMR) is designed to help achieve optimal treatment, such as patient adherence. This study aimed to determine adherence levels and T2DM blood sugar management. This study with a pretest-posttest control group design was carried out at Andalas Public Health Center, Padang City, West Sumatra-Indonesia with 62 randomly selected respondents and then divided into two groups (pillbox and non-pillbox). The adherence levels were assessed by the pill count method. Changes in blood sugar levels are associated with adherence levels. The results showed an increase in the T2DM adherence level of patients using the pillbox at 7.360% and a decrease in blood sugar levels in those who used the pillbox at 61.161 mg/dL. There was a significant difference in the adherence between patients' levels using the pillbox and non-pillbox with a value of 0.011 (p <0.05). Similarly, the patient's blood sugar levels between the two groups showed a significant difference with a value of 0.007 (p<0.05). The application of HMR to patient adherence is considered to have a role in managing T2DM blood sugar.
The Effect of Medication Adherence and Asthma Control in Asthma Patients at a Public Health Center in Padang, Indonesia Dita Permatasari; Dian Ayu Juwita; Hesti Rachmawati Putri; Nurul Qalbi Desri
Jurnal Sains Farmasi & Klinis Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.190-195.2022

Abstract

Asthma is characterized by reversible swelling or narrowing of the airways. Low adherence can negatively affect the effectiveness of therapy, increasing asthma morbidity and mortality. The long-term goal of asthma treatment is to achieve and maintain controlled asthma, but this goal is still challenging for most patients. This study examines the relationship between medication adherence and asthma control in patients. This study is observational, with a cross-sectional approach conducted on 40 asthma patients who received treatment at a Public Health Center. Patient medication adherence was measured by Medication Possession Ratio (MPR) method, and the level of control was measured by the Asthma Control Test (ACT) questionnaire. The results showed that most patients based on sociodemographic characteristics were female (80.0%), elderly group ≥60 years (45.0%), high school education (55.0%), and housewives (45.0%). The category of medication adherence was divided into 47.5% adherent patients and 52.5% non-adherent patients. The level of patient control was divided into fully controlled (2.50%), partly controlled (35.0%), and uncontrolled (62.5%). There was a significant relationship between adherence and asthma control (r=0.508; p<0.05). Therefore, improving patient medication adherence can potentially improve asthma control levels.
Edukasi DAGUSIBU (dapatkan, gunakan, simpan, dan buang) Obat untuk Masyarakat Karang Taruna, Jorong Malana Ponco, Tanah Datar Rahmi Yosmar; Dita Permatasari; Najmiatul Fitria
Warta Pengabdian Andalas Vol 30 No 3 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.3.545-553.2023

Abstract

DAGUSIBU stands for get, use, save, and throw away. In this program, people can manage and use drugs properly and correctly. As the frontline in medicine, pharmacists must carry out socialization to create a drug-aware society. The Faculty of Pharmacy Universitas Andalas conducted community service through DAGUSIBU socialization to get an overview of knowledge regarding the management and use of drugs in the Karang Taruna Community in Jorong Malana Ponco, Tanah Datar Regency. Was DAGUSIBU counselling used, followed by filling out the questionnaire about drug use? Of the 34 participants who attended, 16 participants filled out drug use questionnaires. Most participants were women with an age range of 54.81 ± 14.44. From the questionnaire obtained, the initial picture of the Jorong Malano community's knowledge of DAGUSIBU is not very good. Based on these results, it can be concluded that community knowledge about DAGUSIBU can still be increased with continuous socialization and intensive education
Comparative Utility of Doxorubicin, Cyclophosphamide, and Docetaxel in Breast Cancer Treatment in West Sumatera. Najmiatul Fitria; Intan Nur Rahmadani; Dita Permatasari; Fitri Handayani
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 2 (2024)
Publisher : Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.40914

Abstract

The large number of breast cancer cases in Indonesia and the high cost of treatment cause the need for utility analysis. West Sumatra province ranks second with the highest prevalence of breast cancer in Indonesia. This study aimed to determine the quality of life of breast cancer patients at the national referral hospital Dr. M. Djamil, West Sumatra, who underwent chemotherapy. This study used a cross-sectional design from January to April 2024. Data collection was done prospectively by filling out questionnaires at the Chemotherapy Unit. Utility value was obtained from filling out a questionnaire with the EQ-5D-5L instrument. Data were analyzed using the Mann-Whitney and Kruskal-Wallis tests. The data obtained was 47 respondents who received Doxorubicin and Cyclophosphamide chemotherapy regimen (24 respondents) and a Docetaxel chemotherapy regimen (23 respondents), all of whom met the inclusion criteria in this study. The average utility value obtained for the doxorubicin and cyclophosphamide regimes is 0.637, and the average utility value for the docetaxel regimen is 0.704. Age did not affect utility (p>0.05), while recent education, occupation, and patient origin affected utility (p<0.05). Both regimens provided similar perceived quality of life and overall health status as measured by utility and VAS scores, suggesting comparable patient-reported quality of life outcomes between these chemotherapy treatments.
Assessing Patient Satisfaction and Sociodemographic Determinants in Outpatient Pharmaceutical Care Dian Ayu Juwita; Chofifah Putri Isnania Syaiful; Dita Permatasari
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 8 No. 1 (2026)
Publisher : Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v8i1.51282

Abstract

Abstract: Patient satisfaction is an important indicator of pharmaceutical service quality, reflecting the interaction between healthcare providers and patients. The shift from drug-oriented to patient-oriented care requires healthcare professionals to improve service quality to meet patient needs and expectations. This study aimed to evaluate patient satisfaction with pharmaceutical services at the Outpatient Pharmacy of Semen Padang Hospital and its relationship with sociodemographic characteristics, including gender, age, education, occupation, and payment type. This study used a descriptive quantitative method with a cross-sectional approach using the Larson questionnaire as the research instrument. Data were analyzed using the Chi-square and Spearman tests. The study involved 391 patients who met the inclusion criteria at the Outpatient Pharmacy of Semen Padang Hospital. Most respondents were female (67.3%), adults (81.1%), had a high school education (37.1%), were unemployed (65.7%), and used BPJS insurance (82.1%). Overall, patient satisfaction with pharmaceutical services was categorized as “satisfied” with a mean score of 3.87. The Friendly Explanation dimension showed a higher score (3.95) than the Managing Therapy dimension (3.77). Gender, age, and occupation did not affect patient satisfaction (p>0.05), while education and payment type affected patient satisfaction (p<0.05). Overall, patients at the Outpatient Pharmacy of Semen Padang Hospital were satisfied with the pharmaceutical services provided, indicating good service quality and positive patient perceptions toward pharmaceutical care.                                                                                                                                                       Keywords: Outpatient Pharmacy, Patient Satisfaction, Pharmacy Services, Sociodemographic Characteristics
EDUKASI PENGGUNAAN OBAT BERBASIS KUNJUNGAN RUMAH UNTUK MENINGKATKAN PENGETAHUAN MASYARAKAT DI NAGARI SIKUCUR, KABUPATEN PADANG PARIAMAN Lailaturrahmi Lailaturrahmi; Elsa Badriyya; Annisa Fauzana; Dita Permatasari
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 1 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i1.450

Abstract

The trend of independent drug use behavior (self-medication) among Indonesian people, especially in West Sumatra Province, continues to increase. Without knowledge about the correct use of drugs, people will be at risk to drug use problems. Therefore, education on drug use needs to be implemented to increase public knowledge regarding drug use. By increasing their knowledge, the public will have rational drug use behavior. The aim of this community outreach is to increase public knowledge regarding the use of over-the-counter drugs and limited over-the-counter drugs in treating health problems. The method of activity carried out is education through face-to-face home visits. This activity was carried out in Nagari Sikucur, V Koto Kampung Dalam District, Padang Pariaman Regency. There were 30 community members or family representatives who were the targets of this drug use education and home visit. The implementation of this activity involved five teams consisting of pharmacy lecturers with pharmacists’ qualification, Master of Pharmacy students who had registered as pharmacists, and Bachelor of Pharmacy students. The activity started with an introduction, continued with a pre-test, providing education, post-test, and handing over self-medication drug packages to the community. The results of this home visit-based education show that the community's knowledge score regarding drugs is higher than before the education. It can be concluded that the objectives of this activity were achieved well. To achieve better activity results, preliminary studies, collaboration with stakeholders, time allocation, and adequate technical preparation of activities are required.
Patient Satisfaction with Pharmaceutical Services at a Hospital Outpatient Pharmacy in West Sumatra, Indonesia Dian Ayu Juwita; Nurul Qalbi Desri; Dita Permatasari
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.324-330

Abstract

Background: Patient satisfaction stands as a metric for evaluating the quality of pharmaceutical services. The presence of community requests for high-quality pharmaceutical services has driven pharmacy personnel to enhance these services, aiming to establish patient satisfaction. Objective: The objective of this research is to assess the degree of patient satisfaction with pharmaceutical services in the outpatient pharmacy and to explore how this satisfaction is linked to the patients' sociodemographics. Methods: Conducted at Padang Panjang Hospital's Outpatient Pharmacy in West Sumatra, Indonesia, this descriptive research employed a questionnaire administered directly to patients. The method used involves a questionnaire consisting of 20 questions divided into two dimensions: Friendly Explanation (containing 11 questions) and Managing Therapy (containing nine questions). The questionnaire's validity (r > 0.632) and reliability (0.97). Data analysis was performed utilizing the Likert scale. Results: There were a total of respondents in this study (365 patients). Most of them (64.4%) were female, in the pre-elderly age group (45.2%), had completed high school (41.1%), and were housewives (31.8%). In general, the level of patient satisfaction is categorized as satisfied, with an average score of 3.49. Specifically, the "Friendly Explanation" got a score of 3.69, and the "Management of Therapy" got a score of 3.25. The study indicated notable statistical disparities in patient satisfaction levels based on age, education, and occupation (p<0.05), but gender did not have a significant impact (p>0.05). Conclusion: In summation, the study found that patients were satisfied with the pharmaceutical services at Padang Panjang Hospital's Outpatient Pharmacy.
Co-Authors Almahdy Ahmadin Chofifah Putri Isnania Syaiful Dian Ayu Juwita Dian Ayu Juwita Elsa Badriyya Fauzana, Annisa Fitri Handayani Hesti Rachmawati Putri Indri Oktavia Intan Nur Rahmadani Julio Fajar Rahmat Illahi Lailaturrahmi Lailaturrahmi Najmiatul Fitria Nazar, Armenia Nurul Qalbi Desri Nurul Qalbi Desri Rahmi Yosmar Rahmi Yosmar Resa Lailiani Wilnando Mariza Yelly Oktavia Sari