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TINJAUAN AKUMULASI SEFTRIAKSON DARI DATA URIN MENGGUNAKAN ELEKTROFORESIS KAPILER PADA PASIEN GANGGUAN FUNGSI GINJAL STADIUM TIGA Muslim Suardi; Raveinal Raveinal; Lisa Oktia Sari; Lailaturrahmi Lailaturrahmi
Jurnal Ipteks Terapan Vol 11, No 2 (2017): JIT
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (691.469 KB) | DOI: 10.22216/jit.2017.v11i2.509

Abstract

Ceftriaxone is a third-generation cephalosporin which are excreted mostly via the kidneys. Drugs which are eliminated primarily by the kidneys may accumulate in the patients with impaired renal function. Ceftriaxone is widely used in DR.M.Djamil Hospital Padang. The dosage adjustment for this drug has not yet performed in the hospital so far. This study was conducted in patients who suffered from stage 3 renal failure, received ceftriaxone therapy, and were 20-65 years of age. Urine samples were collected from patients at 4, 4.5, 5.75, 6.5, 7.75, and 8.25 hours after drug administration. Samples were analyzed using capillary electrophoresis. The buffer used was sodium tetraborate with pH of 9, concentration of 50 mM and pKa 9,24. The absorbance of solutions were measured at wavelength of 241.2 nm. From the standard calibration curve of ceftriaxone, the equation of Y = 4.455x - 2.297 (R2 = 0.995), (SD =1.40) was obtained. The migration time of ceftriaxone was 9 minutes. The LOD and LOQ were 0.94 and 3.14 µg/mL, respectively. The elimination rate and elimination half life were 0.046/h and 15,06 h, respectively. Du cumulative and acumulation fraction of drugs were 365.10 mg and 0.33 (33%), respectively. Dmax and Dmin were 2.985 and 985 mg, respectively. Cmax and Cmin were 224,43 and 74,06 mg/L, respectively. The accumulation index of the drug was 1.49. Cl. AUC0˜ and the CpO were 0.612 L/h, 3.268 mg h/L and 150.37 mg/L, respectively. Impaired renal function may affect pharmacokinetic parameters such as elimination rate, elimination half-time, and drug clearance.  
CONTINUITY OF CARE PADA NEONATUS DAN BAYI DI ERA PANDEMI COVID-19 DI SUMATERA BARAT Lusiana El Sinta Bustami; Yulizawati Yulizawati; Erda Mutiara Halida; Fitrayeni Fitrayeni; Rafika Oktova; Laila Rahmi; Ulfa Farrah Lisa; Aldina Ayunda Insani; Uliy Iffah; Feni Andriani; Miranie Safaringga
LOGISTA - Jurnal Ilmiah Pengabdian kepada Masyarakat Vol 5 No 1 (2021)
Publisher : Department of Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Andalas Kampus Limau Manis - Padang, Sumatera Barat Indonesia-25163

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/logista.5.1.161-165.2021

Abstract

Bayi Baru Lahir dan neonatus memiliki resiko ganggguan kesehatan paling tinggi, berbagai masalah kesehatan bisa muncul, sehingga tanpa penanganan yang tepat, akan memiliki dampak berbahaya pada bayi. Saat ini, Indonesia sedang menghadapi bencana nasional non alam Covid-19 sehingga pelayanan kesehatan maternal dan neonatal menjadi salah satu layanan yang terkena dampak baik secara akses maupun kualitas. Kasus Covid-19 untuk wilayah Sumatera Barat yang masih meningkat dan kasus positif tidak hanya terjadi pada wanita yang sehat, namun juga ada yang tanpa gelaja, wanita hamil, menyusui, bayi baru lahir, anak dan dewasa. Agar ibu dan bayi tetap dapat selalu mendapatkan asuhan selama masa pandemi, maka sebagai bidan dapat dilakukan asuhan kebidanan berkelanjutan (Continuity of care) pada ibu dan keluarga dengan lebih inovatif dengan tetap harus memperhatikan protokol kesehatan dalam memberikan asuhan pada ibu dan bayi. Tujuan yang akan dicapai dalam kegiatan ini adalah meningkatnya angka derajat kesehatan yang lebih baik pada bayi, sehat fisik dan tumbuh serta berkembang secara normal di era pandemi covid-19. Metode yang dipakai dengan melakukan survey dan wawancara untuk pengumpulan data, analisis data, penyajian data, merumuskan pembahasan dan selanjutnya diberikan komunikasi, informasi dan edukasi (KIE) dilakukan dengan metode daring dengan menggunakan aplikasi SMS,video conference, zoom,WA dan aplikasi lainnya. Kata kunci : Bayi Baru Lahir, Neonatus, Covid-19, Continuity of Care ABSTRACT Newborn and neonatus have the highest risk of health problems, various health problems can arise. So that without proper handling, it will have a dangerous impact on the baby. Currently, Indonesia is facing a national non-natural disaster Covid-19 so that maternal and neonatal health services are among the services that are affected both in terms of access and quality. Covid-19 cases for the West Sumatra region are still increasing and positive cases do not only occur in healthy women, but also those who are uneasy, pregnant, breastfeeding, newborns, children and adults. So that mothers and babies can always receive care during the pandemic, as a midwife continuous midwifery care can be carried out for mothers and families more innovatively while still having to pay attention to health protocols in providing care to mothers and babies. The goals in this event that will be achieved are to increase the health status in babies, physically healthy and grow and develop normally in the era of the Covid-19 pandemic. The method used by conducting surveys and interviews for data collection, data analysis, data presentation, formulating discussions and give the education, information by online using SMS, video conferencing applications, zoom, WA and other video applications. Keywords: Newborns, Neonates, Covid-19, Continuity of Care
PEMBERDAYAAN MASYARAKAT DI NAGARI LUMPO KABUPATEN PESISIR SELATAN Yusrawati Yusrawati; Yulizawati Yulizawati; Lusiana El Sinta Bustami; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila; Feni Andriani; Erda Mutiara Halida; Fitrayeni Fitrayeni; Uliy Iffah; Miranie Safaringga; Laila Rahmi; Rafika Oktova; Ulfa Farah Lisa; Muhammad Iqbal; Rahmat Syawqi; Syandrez Prima Putra; Liganda Endo Mahata; Elfira Yusri
BULETIN ILMIAH NAGARI MEMBANGUN Vol 2 No 4 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.712 KB) | DOI: 10.25077/bina.v2i4.130

Abstract

Pesisir Selatan Regency is one of the districts with 15 sub-districts with the largest population in IV Jurai District. The number of deaths per year on the South Coast fluctuates. In 2015 the number of infant deaths increased from 6 to 42 people (male 29 and 13 female) from the previous year, AKABA of 47 from 18 in the previous year. There were 16 toddlers with herniated nutrition and many pregnant women, namely around 273 pregnant women. Based on a preliminary study conducted by the activity implementation team at the Lumpo Public Health Center, IV Jurai District, Pesisir Selatan Regency, it is known that there is no ultrasound examination facility in pregnancy and prenatal yoga facilities at the Lumpo Puskesmas, besides that there are no similar activities carried out at SD Negeri 016 and MTsN. Nagari Lumpo which is included in the work area of Lumpo Puskesmas. Several tests can be done during pregnancy as an effort to detect early and prevent complications and growth disorders in the fetus. Among others, by monitoring weight gain during pregnancy, conducting general examinations (vital signs), physical examinations that focus on the breasts, abdomen, genitalia with inspection, palpation, auscultation, and percussion, ultrasonography (USG) examinations, and performing supporting examinations in the form of laboratory examination (hemoglobin examination). The result of this activity is an increase in each target group's quality of life by the stages of life after this activity.
The Relationship Of The Characteristics Of The Mother With The Type Of Delivery Laila Rahmi; Lusiana El Sinta Bustami
Journal of Midwifery Vol 6, No 2 (2021): Published on Desember 2021
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.6.2.37-44.2021

Abstract

The incidence of deliveries by cesarean section is reported to have increased worldwide and exceeded the range recommended by the World Health Organization (WHO) which is 10-15% as an effort to save the lives of mothers and babies. Latin America and the Caribbean region were the highest contributors at 40.5%. Riskesdas data in 2018 shows that the prevalence of delivery by caesarean section in Indonesia is 17.6%. This type of research is cross sectional with secondary data sources. The study was conducted from May to November 2021 at the Padang City Government and Private Hospital. The population was all mothers who gave birth during the survey period from January 1 to December 31, 2020 at hospitals in the city of Padang (dr. Reksodiwiryo Hospital, Andalas University Hospital, and Ibu Sina Islamic Hospital) with samples of all populations that met the inclusion and exclusion criteria. Data were collected in a data collection format, analyzed by univariate analysis and bivariate analysis. Most (82.7%) deliveries were performed by cesarean section, a small percentage (23.2%) were high risk mothers (< 20 years and > 35 years), a small percentage (37.9%) gave birth to their first child. and more than 4 children, a small percentage (18.6%) of maternity mothers had education at the middle school level and below, there was a relationship between maternal age and the type of delivery performed, and there was no relationship between parity and maternal education with the type of delivery performed. Health workers, especially midwives, are expected to further improve health promotion related to the impact and dangers of sectio caesarea with non-medical indications and increase the provision of midwifery care to pregnant women to optimize the position of the fetus so that mothers can give birth normally vaginally
FACTORS AFFECTING THE VISUAL INSPECTION OF ACETIC ACID EXAMINATION (IVA) IN PADANG CITY 2019 Lusiana El Sinta B; Laila Rahmi; Uliy Iffah
Journal of Midwifery Vol 5, No 1 (2020): Published on June 2020
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.5.1.20-30.2020

Abstract

Cervical cancer is the fourth most common cancer in women with a mortality rate of 6.8% (WHO, 2015; Globocan, 2012). The incidence of cervical cancer ranks second after breast cancer in Southeast Asia and Indonesia. Based on data from the Republic of Indonesia Ministry of Health 2015, cervical cancer is the cancer with the highest prevalence of 0.8 per 1000 population (Ministry of Health Republic of Indonesia, 2015). The high prevalence of cancer in Indonesia requires prevention and early detection by health service providers. The purpose of this study was to determine the factors that influence the inspection of Acetic Acid Visual Inspection (IVA) in Padang City.This type of research is quantitative with cross sectional design. The study was conducted at the Padang City Health Center in April-November 2019. The population was all women aged 30-50 years who were at the Padang City Health Center, amounting to 10,670 people, with a sample of 73 people taken by consecutive sampling technique. Data were collected by questionnaire and analyzed by univariate and bivariate analysis.More than half (64.4%) of women of childbearing age (WUS) have never had an IVA examination, more than half (58.9%) of women have a risk age, less than half (39.7%) women have low levels of education , more than half (60.3%) WUS with working status, there was no relationship between the age of WUS with IVA examination (p value = 0.182), there was a relationship between WUS education level and IVA examination (p value = 0.031), there was no relationship between the status of WUS work and IVA examination (p value = 0.404). It is expected that officials and leaders of puskesmas will develop more attractive ways to be able to convince and increase awareness and concern of the WUS themselves in conducting IVA examinations.
STUDENT ACHIEVEMENT IN A PHARMACOTHERAPY PRACTICE COURSE: A CASE STUDY AT AN INDONESIAN PHARMACY SCHOOL Lailaturrahmi Lailaturrahmi; Elsa Badriyya
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 9, No 3 (2020): November
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.54653

Abstract

Background: Indonesian pharmacy schools are expected to meet required clinical pharmacy components and the proportion of practical courses according to nationally established standards. This is essential to produce competent Indonesian pharmacists. The implementation of Pharmacotherapy of Gastrointestinal, Respiratory Tract Diseases, and Special Conditions Practice was one of the measures taken to meet this requirement. This case study aims to explore obstacles in Pharmacotherapy of Gastrointestinal, Respiratory Tract Diseases, and Special Conditions Practice.Case discussion: Pharmacotherapy of Gastrointestinal, Respiratory Tract Diseases, and Special Conditions (FAF 314) Practice was conducted using group case study with SOAP (subjective, objective, assessment, plan) worksheet. During the sixth week of practice, a modified OSCE was conducted to assess the learning process. The skills that were assessed included problem identification, problem-solving, drug information service, effective communication, as well as attitude and professionalism. However, the students’ average score in this assessment was about 1-2 of maximum score 3, and the required passing score was 2. Conclusion: The sub-optimal students’ achievement in the mid-term assessment of Pharmacotherapy of Gastrointestinal, Respiratory Tract Diseases, and Special Conditions Practice may be due to the students’ obstacles in understanding the information from literature and showing effective communication skills and professional attitude in drug information provision. To address these issues, further measures such as constructive alignment analysis of this practice, revising practice activities design and allocating adequate time to practice effective communication skills and professional attitude in drug information provision. Keywords: constructive alignment, communication, pharmacotherapy practice, OSCE, SOAP
DIVERSIFIKASI OLAHAN PRODUK JAHE MERAH MELALUI PELATIHAN PEMBUATAN PERMEN JAHE PADA USAHA BERKEMBANG NAGI SIPADEH Felga Zulfia Rasdiana; Ares Albirru Amsal; Lailaturrahmi Lailaturrahmi
LOGISTA - Jurnal Ilmiah Pengabdian kepada Masyarakat Vol 6 No 1 (2022)
Publisher : Department of Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Andalas Kampus Limau Manis - Padang, Sumatera Barat Indonesia-25163

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/logista.6.1.162-166.2022

Abstract

Nagi Sipadeh merupakan salah satu usaha berkembang yang menjadi mitra pengabdian masyarakat LPPM Universitas Andalas yang memiliki keinginan besar untuk terus berinovasi mengembangkan berbagai jenis produk olahan jahe merah. Salah satu produk yang ingin dikembangkan adalah permen jahe merah. Dalam upaya pengembangan produk permen jahe merah, masih banyak kendala dan permasalahan yang dialami oleh Nagi Sipadeh terutama kurangnya pengetahuan tentang teknologi produksi permen. Melalui kegiatan pengabdian kepada masyarakat yang dilakukan ini diharapkan dapat membantu usaha Nagi Sipadeh untuk meningkatkan keterampilan dan kemampuan dalam memproduksi permen berbahan baku jahe merah. Kegiatan pengabdian kepada masyarakat ini dilaksanakan dalam tiga bentuk kegiatan, yaitu penyuluhan, pelatihan, dan bimbingan berkelanjutan. Pelatihan yang dilakukan mencakup pada teknologi produksi permen yang meliputi komposisi bahan-bahan yang diperlukan dalam pembuatan permen disertai edukasi mengenai fungsi dan peranan masing-masing bahan tersebut dalam komposisi permen, kemudian dilanjutkan dengan penyampaian cara pengolahan yang tepat serta prosedur pengemasan permen yang baik. Hasil dari kegiatan ini Usaha Nagi Sipadeh mendapatkan pengetahuan dan keterampilan mengenai proses pengolahan permen baik dalam bentuk permen keras maupun permen lunak serta mengetahui teknik pengemasan permen yang tepat. Kata kunci: Jahe merah, Nagi Sipadeh, permen ABSTRACT Nagi Sipadeh is one of the developing businesses that is a community service partner of LPPM Andalas University who has a great desire to continue to innovate in developing various types of processed red ginger products. One of the products to be developed is red ginger candy. In an effort to develop red ginger candy products, there are still many obstacles and problems experienced by Nagi Sipadeh, especially the lack of knowledge about candy production technology. Through this community service activity, it is hoped that it can help Nagi Sipadeh's efforts to improve skills and abilities in producing of red ginger candy. This community service activity is carried out in three forms of activity, namely counseling, training, and ongoing guidance. The training carried out covers candy production technology which includes the composition of the ingredients needed in making candy along with education about the function and role of each of these ingredients in candy composition, then continued with the delivery of proper processing methods and good candy packaging procedures. As a result of this activity, Nagi Sipadeh's business gained knowledge and skills regarding the candy processing process, both in the form of hard candy and soft candy, as well as knowing the right candy packaging technique. Keywords: Red ginger, Nagi Sipadeh, candy
Relationship between occupation and education with the choice of IUD contraception in Pauh District, Padang City, West Sumatra. Fitri Khoiriyah; Ariadi; Yusrawati; Laila Rahmi
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.897

Abstract

High population growth is a significant problem faced by the Indonesian people in the field of population. Efforts to create quality families are primarily targeted at controlled population growth and increasing the quality of small families, as indicated by the increased use of rational, effective, and efficient contraceptive methods, namely the use of Long-Term Contraceptive Methods (MKJP). Referring to the 2020-2024 BKKBN Strategic Plan, the BKKBN vision has been set: "Creating quality families and balanced population growth to support the achievement of an advanced Indonesia that is sovereign, independent, and has a personality based on mutual cooperation" (BKKBN, 2021). The purpose of this research was to determine the relationship of education and occupation with the selection of IUD contraceptives in the work area of ​​Pauh Health Center. This research was a cross-sectional comparative. The populations in this research were all women of childbearing age (WUS), current family planning acceptors aged 15-49 years who used IUD and non-IUD contraception. The samples of this research were 49 IUD users and 149 non-IUD users. The instruments were a questionnaire. The bivariate analysis used Chi-Squere. The results the bivariate study found that there was a not significant relationship between occupation with the selection of IUD contraceptives (p = 0.251) and there was a significant relationship between education and the selection of IUD contraceptives (p = 0.001) This study concludes that there is no relationship between occupation with the choice of IUD contraceptives and there is a relationship between education and the choice of IUD contraceptives
Analisis Pelayanan Antenatal Care saat Masa Pandemi COVID-19 di Puskesmas Air Tawar Annisa Karima Harda; Laila Rahmi; Miranie Safaringga
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 4 (2022): Oktober 2022
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf13414

Abstract

The COVID-19 pandemic has had an impact on family health services, especially efforts to prevent death, including maternal mortality which is an indicator that determines the degree of public health. One of the efforts to reduce maternal mortality is the antenatal care program. The purpose of this study was to find out about antenatal care services during the COVID-19 pandemic at the Air Tawar Health Center. This study used a qualitative method with a systems approach. Data collection was carried out through in-depth interviews, observation, and document review. The results showed that for the input component, human resources were sufficient and according to standards. Funds are available and sourced from BOK and BPJS. SOPs are available which refer to the RI Ministry of Health Guidelines, but the officers did not carry out the SOPs perfectly. The facilities and infrastructure are complete. For the process component, the health center has carried out the flow of antenatal care services and health protocols in accordance with the guidelines, but officers still do not use complete PPE according to service standards. For the output component, the coverage of ANC services has decreased significantly during the pandemic and is still far from the national target. For the outcome component, pregnant women are satisfied with antenatal care services, but some pregnant women do not have routine checks. It was concluded that the antenatal care program at the Air Tawar Health Center was generally running well, but staff still needed to pay more attention to service procedures and the use of PPE.Keywords: antenatal care; COVID-19; public health center ABSTRAK Pandemi COVID-19 berdampak pada pelayanan kesehatan keluarga terutama upaya pencegahan kematian, termasuk kematian ibu yang menjadi indikator yang menentukan derajat kesehatan masyarakat. Salah satu upaya untuk menurunkan angka kematian ibu adalah program antenatal care. Tujuan penelitian ini adalah untuk mengetahui pelayanan antenatal care saat masa pandemi COVID-19 di Puskesmas Air Tawar. Penelitian ini menggunakan metode kualitatif dengan pendekatan sistem. Pengumpulan data dilakukan melalui wawancara mendalam, observasi, dan telaah dokumen. Hasil penelitian menunjukkan bahwa untuk komponen input, sumber daya manusia sudah mencukupi dan sesuai standar. Dana tersedia dan bersumber dari BOK dan BPJS. SOP sudah tersedia yang mengacu kepada Pedoman Kemenkes RI, namun petugas tidak melakukan SOP dengan sempurna. Sarana dan prasarana sudah lengkap. Untuk komponen proses, puskesmas sudah melakukan alur pelayanan antenatal care dan protokol kesehatan sesuai dengan pedoman, namun petugas masih belum menggunakan APD lengkap sesuai standar pelayanan. Untuk komponen output, cakupan pelayanan ANC mengalami penurunan yang signifikan selama masa pandemi dan masih jauh dari target nasional. Untuk komponen outcome, ibu hamil sudah puas dengan pelayanan antenatal care, namun beberapa ibu hamil tidak melakukan pemeriksaan rutin. Disimpulkan bahwa program antenatal care di Puskesmas Air Tawar secara umum berjalan dengan baik, namun petugas masih perlu lebih memperhatikan prosedur pelayanan dan penggunaan APD.Kata kunci: antenatal care; COVID-19; puskesmas
Pengaruh Jenis Vaksin Covid-19 pada Kualitas Hidup Terkait Kesehatan (HRQoL) Masyarakat di Kota Padang dan Pariaman Boy Andre; Lailaturrahmi Lailaturrahmi; Almahdy A; Armenia Armenia
Jurnal Sains Farmasi & Klinis Vol 9, No 3 (2022): J Sains Farm Klin 9(3), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.3.277-284.2022

Abstract

Covid-19 (Corona Virus Disease-2019) merupakan penyakit infeksi yang disebabkan oleh virus coronavirus 2 yang sangat mudah menular dan menyebabkan infeksi pada sistem pernafasan. Vaksinasi Covid-19 adalah salah satu upaya pencehagan penularan, dimana jenis vaksin yang diberikan kepada masyarakat ditetapkan oleh pemerintah. Tujuan penelitian ini adalah menganalisis pengaruh jenis vaksin Covid-19 terhadap kualitas hidup terkait kesehatan (HRQoL) di Kota Padang dan Pariaman. Penelitian dilakukan dengan menyebarkan dalam jaringan kuisioner generik WHOQOL-BREF yang berisi 26 pertanyaan pada bulan Juli – September 2022. Jenis vaksin merupakan variabel independen sedangkan data sosiodemografi responden yang meliputi jenis kelamin, usia, status perkawinan, pekerjaan, kota domisili, pendidikan terakhir, dan penyakit penyerta sebagai covariat. Kuisioner diolah secara statistik menggunakan SPSS versi 26 dengan analisis univariat. Vaksin Covid-19 yang diterima oleh responden yaitu Sinovac dan Sinopharm (inactivated virus), Moderna dan Pfizer (mRNA), serta Astra Zeneca (Non-Replicating Viral Vector). Kuisoner yang diisi secara  lengkap oleh 418 responden didapatkan hasil dimana sebanyak 242 dan 81 responden menyatakan kualitas hidup terkait kesehatan mereka berstatus baik dan sangat baik, sedangakan  93 dan 2 repsonden menyatakan biasa dan buruk. Hasil uji statistik menunjukkan tidak terdapat pengaruh yang signifikan (p>0,05) antara jenis vaksin terhadap ke empat domain pada HRQoL. Namun, terdapat pengaruh yang signifikan (p<0,05) pada covariat yaitu status perkawinan, pekerjaan dan pendidikan terakhir terhadap semua domain pada HRQoL.