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All Journal AcTion: Aceh Nutrition Journal Indonesian Journal for Health Sciences (IJHS) Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Journal SAGO Gizi dan Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal PADE: Pengabdian & Edukasi Jurnal Ilmiah Farmasi Simplisia
Munira Munira
Jurusan Farmasi Poltekkes Kemenkes Aceh
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Veterinary

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Analisis senyawa kimia dan uji antihiperglikemia daun petai cina (Leucaena leucocephala) dari kawasan geotermal Ie Seum Aceh Besar Noni Zakiah; Munira Munira; Berwi Fazri Pamudi; Muhammad Nasir; Frengki Frengki; Halimatussakdiah Halimatussakdiah
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3A (2024): Agustus
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3A.1848

Abstract

Background: Hyperglycemia can cause serious complications due to the side effects of synthetic drugs used. Traditional medicines, such as petai cina, which contain secondary metabolite compounds like flavonoids, saponins, and steroids, have antidiabetic potential.Objectives: Hyperglycemia can cause serious complications due to the side effects of synthetic drugs used. Traditional medicines, such as petai cina, which contain secondary metabolite compounds like flavonoids, saponins, and steroids, have antidiabetic potential.Methods: This experimental research used a Completely Randomized Design (CRD) with 11 treatments: Na CMC, glibenclamide, and ethanol, ethyl acetate, and N hexane extracts of petai cina leaves at doses of 200 mg/kg BW, 400 mg/kg BW, and 600 mg/kg BW each. Each treatment was repeated five times.Results: Phytochemical screening showed that petai cina leaf extract contains phenolics, flavonoids, steroids, and saponins. GC-MS tests identified antidiabetic compounds such as phytol, squalene, and octacosanol. The antihyperglycemic test showed a significant decrease in blood sugar levels in rats after administration of petai cina leaf extract (P = 0,00). The decrease in blood sugar levels increased over time after the extract was given.Conclusion: Chinese petai leaf extract sourced from the Ie Seum Aceh Besar geothermal area exhibits an antihyperglycemic effect on male rats. KeywordsAntihyperglycemic, Leucaena leucocephala, geothermal, Diabetes, Traditional medicine
Co-Authors Aida Fithri Andriani Andriani Berwi Fazri Pamudi Cut Aja Nuraskin Cut Fardilla Dewi Sarfica Dhea Amalia ferissa safira Frengki Frengki Galuh Trioktafiani Halimatussakdiah Hayati, Rima Intan Liana Irma Dewiyanti Mardiana Putri Muhammad Nasir Muhammad Nasir Muhammad Nasir Muhammad Nasir Muhammad Nasir Muhammad Nasir Nazarul Mastura Noni Zakiah Noni Zakiah Noni Zakiah Novi Yanti Nunung Sri Mulyani Rasidah Rasidah Rasidah Rasidah Reca Reca Riska Maisarah Rita Novita Sarah Desia Teuku Salfiyadi Vonna Aulianshah Wiqayatun Khazanah Wirza Wirza