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Gambaran Pemeriksaan Kadar SGOT dan SGPT pada Penderita Tuberkulosis Paru Siti Chairini; Widodo Widodo
Jaringan Laboratorium Medis Vol 2 No 1 (2020): Mei 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i1.6266

Abstract

Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT > normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT > normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT > normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.
Skrining Gestational Diabetes Mellitus (GDM) pada Wanita Hamil dan Diabetes pada Lansia di Wilayah Getasan Widodo Widodo; Ahmad Riyadi; S.Y. Didik Widiyanto; Aulia Qurotul Ayuni
Jaringan Laboratorium Medis Vol 5 No 1 (2023): Mei 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.9661

Abstract

Type 1 and type 2 diabetes are influenced by genetic and environmental factors causing a decrease in β cell function resulting in hyperglycemia. Patients with hyperglycemia are at risk for chronic complications. The elderly have the potential to suffer from diabetes mellitus due to the age factor and the decreased ability of the body's metabolism. Whereas in pregnant women any hyperglycemia is considered gestational diabetes mellitus (GDM), regardless of diabetes occurring before or during the current pregnancy GDM is diabetes diagnosed in the second trimester or later. This study aims to map cases of diabetes and gestational diabetes. This research is a non-experimental study with a survey method approach without intervention that is descriptive analytic research results of 48 people with a total of 14 men and 5 pregnant women out of a total of 34 female respondents. Examination results for supporting examinations obtained the results of 8 glucose samples with levels > 200 mg/dl and those who had diabetes mellitus based on HbA1c examination were 6 people aged 45-65 years and as many as 3 people aged over 65 years. Respondents who had diabetes mellitus were 2 men and 4 women and none of the pregnant women had gestational diabetes. This research has an impact on the people who take part in this activity, one of which is getting education on how to maintain a healthy quality of life in old age and for those who enter the diabetes mellitus screening group, it is continued in the process of care and assistance by the Getasan Health Center.
Gambaran Kadar Hemoglobin pada Calon pendonor Usia lebih Dari 46 Tahun di UDD PMI Kabupaten Jepara Alya Luthfia; Ririh Jatmi Wikandari; Widodo Widodo
Jaringan Laboratorium Medis Vol 6 No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.11437

Abstract

Blood donation is the process of taking a portion of blood from a healthy person then giving it to the person who needs blood. Hemoglobin level examination is one of the donor selection checks to find out whether someone is successful or not to donate blood. A person can donate blood if the hemoglobin level shows a result of 12.5 g / dL – 17 g / dL. A person's hemoglobin level can be influenced by age, because as we get older many organ functions that do not work optimally so that they experience a decrease in Hb levels. The purpose of this study was to measure hemoglobin levels in prospective donors aged more than 46 years at UDD PMI Jepara Regency. This type of research uses a quantitative approach with a cross-sectional descriptive study research model taken from the SIMDONDAR database. The population in this study is all potential donors at UDD PMI Jepara Regency in December 2023-January 2024. The data obtained were analyzed univariately. Based on the results of the study, it was found that the majority of prospective donors showed normal hemoglobin levels as many as 480 prospective donors (94.86%), and more prospective donors who had blood type O (+) as many as 187 prospective donors (36.96%), most prospective donors were male as many as 342 prospective donors (67.59%), and the majority of prospective donors were declared to have passed the donor selection as many as 480 prospective donors (94.86%). The impact of the research results obtained by UDD PMI Jepara Regency is that officers are aware of the importance of socializing to the community how important it is to maintain hemoglobin levels before donating blood and recruiting donors from various ages of prospective donors in the Jepara Regency area.
Uji MPN Coliform pada Air Isi Ulang dengan Sterilisasi Sinar UV Widodo Widodo; Dian Yulia Purwanti; S.Y Didik Widiyanto; Devi Etevia Purlinda
Jaringan Laboratorium Medis Vol 8 No 1 (2026): May 2026
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v8i1.14460

Abstract

Wolter Refill water typically undergoes a filtration and sterilization process using 254 nm UV light to sterilize against microbial contamination. This bacterial contamination can be tested using the MPN Coliform test, which is the most important microbiological parameter for drinking water quality. Fecal coliform bacteria are the most commonly used microorganisms as indicators of water pollution, as these bacteria are always present in feces. According to Indonesian Minister of Health Regulation No. 492/MENKES/PER/IV/2010, mandatory standards for drinking water quality are regulated, including physical and microbiological requirements. The purpose of this study was to identify the presence of coliform and fecal coliform bacteria in AMIU sold along Jalan Wolter Monginsidi, Semarang, and to analyze their presence in drinking water. The research method was descriptive. The object of the study was AMIU from eight AMIU depots sold along Jalan Wolter Monginsidi, Semarang, while the subjects were coliform and fecal coliform bacteria. The data collected consists of primary data and supporting data which are then arranged descriptively. Research results There are 3 AMIU depots that are positive for containing Coliform bacteria, namely Depot A4, A5 and Depot A8 with a total Coliform bacteria content of 2 MPN / 100 ml. While the 8 AMIU depots studied did not contain fecal Coliform bacteria, namely 0 MPN / 100 ml. The causes of the presence of Coliform bacteria in positive AMIU samples include the sterilization method only using UV light, the sterilization time is less than 1 hour, the sterilization tool is not replaced periodically, the AMIU storage time at the depot is more than 3 days, the gallon is not washed properly, and the AMIU Laboratory is not checked routinely. Poor results in the test are submitted to the depot manager for follow-up by resetting the sterilization tool.