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Hubungan Onset Keluhan Nyeri Perut dan Jumlah Leukosit dengan Tingkat Keparahan Apendisitis Akut pada Anak Wahyu Jati Wibowo; Tubagus Odih Rhomdani Wahid; Huriatul Masdar
Health and Medical Journal Vol 2, No 2 (2020): HEME July 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.396 KB) | DOI: 10.33854/heme.v2i2.454

Abstract

Latar belakang: Apendisitis akut selalu memerlukan terapi pembedahan. Jika apendektomi tidak dilakukan segera, akan menyebabkan perforasi pada apendiks dan kontaminasi peritoneal. Angka kejadian tertinggi apendisitis adalah pada akhir usia remaja, dengan 5% kejadian pada anak usia dibawah 5 tahun.Tujuan: Mengetahui hubungan antara onset keluhan nyeri perut dengan tingkat keparahan apendisitis akut anak serta mengetahui perbedaan rerata  jumlah leukosit apendisitis akut anak antara apendisitis non komplikata dan apendisitis komplikata. Metode: Penelitian ini merupakan penelitian analitik komparatif dan analitik korelatif dengan pendekatan retrospective. Terdapat sebanyak 68 rekam medis pasien apendisitis akut anak di RSUD Arifin Achmad Provinsi Riau periode Januari 2018 – Desember 2019. Hasil: Penelitian ini didapatkan perbandingan yang sama antara laki-laki dan perempuan, dengan didominasi pada rentang usia 6-12 tahun. Lama onset keluhan nyeri perut didominasi pada lama keluhan lebih dari 48 jam. Terdapat 69,1% apendisitis komplikata. Leukositosis terjadi pada 76,5% pasien. Hasil uji komparatif t tidak berpasangan didapatkan p=0,000, terdapat perbedaan rerata jumlah leukosit yang bermakna antara apendisitis non komplikata dan apendisitis komplikata. Nilai IK95%=4.015,7-6.683,13. Hasil uji korelasi Somers’d antara onset keluhan nyeri perut dengan keparahan apendisitis akut anak didapatkan p=0,00. Kesimpulan: Terdapat perbedaan rerata leukosit yang bermakna antara apendisitis non komplikata dan apendisitis komplikata serta terdapat hubungan yang bermakna antara onset keluhan nyeri perut dengan tingkat keparahan apendisitis akut anak dengan kekuatan hubungan kuat.
Tes Toleransi Glukosa Oral (TTGO) Pasca Pemberian Suspensi Kedelai Dibanding Suspensi Tempe pada Tikus (Rattus norvegicus Galur Wistar) Diabetik Huriatul Masdar; Muhammad Radhiatul Hakiki; Muhammad Rafi Syahputra; Tommy Satriasumatri; Deskafiani Putri; Rizki Bunaya; Desby Juananda
Health and Medical Journal Vol 3, No 2 (2021): HEME July 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.225 KB) | DOI: 10.33854/heme.v3i2.634

Abstract

Introduction: Genistein, daidzein and glicytein are soybean’s isoflavones which have been known having anti diabetic effect. Fermentation process of soybean can lead to formation aglycan isoflavones which have higher bioavailability than unfermented-soybean. Aims: This research was aimed to evaluate the effect of soybean and tempeh (fermented-soybean) administration to oral glucose tolerance test (OGTT) in diabetic rats. Method: Twenty male Rattus norvegicus Wistar strains were used in this experiment, divided into 4 groups: standard, negative control, soybean and tempeh group. Type 2 diabetes in rats was induced by giving streptozotocin (50 mg/kgBW) and nicotinamide (110 mg/kgBW) intraperitoneally. Blood glucose were measured by using blood glucose test meter and classified into diabetes if its level above 200 mg/dL. Soybean (200 mg/kgBW/day) and tempeh (200 mg/kgBW/day) suspension were given by using gastric tube for 30 days. Results: The results showed the means of either fasting blood glucose (FBG) or 2 hours post prandial blood glucose (2hPP) of negative control were persistent above 200 mg/dL on day 15th and 30th  (p> 0,05). In soybean group there was a decrease the mean of FBG on day 15th  (p<0.05) but did not reach the normal level, and on day 30th the mean of FBG was <200 mg/dL (p<0.05) however 2hPP blood glucose was still >200 mg/dL (p<0.05). Furthermore, in tempeh group, the means of either FBG or 2hPP blood glucose reached the normal level in day 15th and 30th (p <0.05). Conclusion: the provision of tempeh was better in controlling blood sugar levels than soybean.
Pengetahuan, Sikap dan Praktik Analis Kesehatan di Rumah Sakit X Provinsi Riau tentang Vaksinasi Hepatitis B Huriatul Masdar; Sri Intan Agusmai; Rahmat Azhari Kemal; Fajri Marindra Siregar; Dedi Afandi
Jurnal Ilmu Kedokteran Vol 16, No 1 (2022): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v16i1.2022.30-35

Abstract

Hepatitis B is still one of public health problems in the world including in Indonesia. The most vulnerable group to hepatitis B virus exposure is healthcare workers including clinical laboratory technicians. The best way to prevent hepatitis B infection is by getting vaccination. Therefore clinical laboratory technicians are among prioritized subject in getting hepatitis B vaccination. However, hepatitis B vaccination for healthcare workers is not an obligation yet. The purpose of this study was to determine the knowledge, attitude and practice of hepatitis B vaccination among clinical laboratory technicians at X Hospital of Riau Province. This descriptive cross-sectional study was carried out between October 2021 and January 2022. Overall, 38 clinical laboratory technicians were recruited for this study. The Kolmogorov-Smirnov test is used to determine the relationship between knowledge with attitudes and practice. The results showed that 52.6% of respondents had good knowledge, 57.9% had a positive attitude and 68.4% had not been vaccinated against hepatitis B. Based on the results of bivariate analysis, there was no relationship between knowledge and attitude (p>0.05) or practice (p>0.05). Although more than 50% of respondents had good knowledge and attitude, the low number of clinical laboratory technicians in getting the hepatitis B vaccine remains a particular concern.
Efek inhibisi ekstrak buah mangrove Sonneratia alba terhadap ekspresi tumor growth factor-beta 1 pada aorta abdominal tikus yang diinduksi aterosklerosis Huriatul Masdar
Jurnal Kedokteran Syiah Kuala Vol 22, No 1 (2022): Volume 22 Nomor 1 Maret 2022
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v22i1.23397

Abstract

Various studies have proven the antioxidant content of Sonneratia alba fruit. Antioxidants are known to play an important role in inhibiting the formation of fibrotic tissue and atheromatous plaques in atherosclerosis, in which TGF- β1 expression plays an important role in the fibrosis process of atherosclerosis. This study aimed to examine the effect of Sonneratia alba mangrove fruit extract on the expression of TGF- β1 in atherosclerosis-induced rat aorta. A total of 18 male rats, aged 6-8 weeks with a body weight of 180-250 grams were used in this study, divided into the standard (S), positive control (P) and treatment group (T). Groups P and T were induced atherosclerosis in initiation phase by giving a high-fat diet 20 grams per day for three days. Group T was given Sonneratia alba mangrove fruit extract at a dose 500 mg/kg b.w/day for three days orally. TGF- β1 expression in rat abdominal aorta was assessed by immunohistochemical techniques and microscopic imaging was performed in fields of view. The percentage of area expressing TGF- β1 was assessed using ImageJ software. The results showed the average percentage of TGF- β1 expression in group P (17,3%) was higher than in group T (12,2%) and S (8,9%). Statistical analysis using One Way Anova test showed a significant difference between groups (p=0,000). Further analysis using Bonferroni test showed a significant difference in groups P and T (p=0,022), T and S (p=0,023) and Pand S (p=0,000). In conclusion, Sonneratia alba mengrove fruit extract was able to inhibit TGF- β1 expression in atherosclerosis-induced rat aorta in initiation phase.
GAMBARAN RINITIS ALERGI PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS RIAU ANGKATAN 2013-2014 Muhammad Rafi; Asmawati Adnan; Huriatul Masdar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

ABSTRACTAllergic Rhinitis is an inflammation reaction at nasal mucous that is caused by allergic reaction mediated by IgE, its identified by symptoms like rinore, sneeze, nasal itch, nasal congestion, itchy and watery red eyes. This research was done to visualizing and evaluating allergic rhinitis among stundents of Riau University’s Medical Faculty Generation 2013/2014. The design of the research was desciptive research wih cross sectional approach using total sampling sample recovery technique. From 293 respondents, 74 was suspected to having allergic rhinitis based from their questioner, physical examination, and skin prick test. From the result of the research, prevalention of allergic rhinitis is 74 students (25.25%). Further description of the research revealed that gender with the most allergic rhinitis suspect is female (19,79%), the most complained symptom is sneeze (03,24%), followed by nasal congestion (85,13%), the most common classification of allergic rhinitis to be the intermitten type (64,86%), the most common degree of allergic rhinitis is moderate-severe (50%). On physical inspection, allergic shiner (86,48%) is the most common physical findings, findings from anterior rhinoscope examination is livid mucous (100%). Tyoe of aeroallergen most commonly found is Dermatophagoides farinae (63,51%) followed by Dermatophagoides pteronyssinus (60,81%) and Blomia Tropicalis (58,10%)Key words : Allergic Rhinits, Nasal mucous inflammation, Skin Prick Test, aeroallergen.
PERILAKU MAHASISWA PRODI PROFESI NERS TERHADAP VAKSINASI HEPATITIS B Huriatul Masdar; Sitti Zuhairah; Rahmat Azhari Kemal; Fajri Marindra Siregar; Dedi Afandi
Jurnal Ners Indonesia Vol 13 No 1 (2022): SEPTEMBER 2022
Publisher : Fakultas Keperawatan, Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/jni.13.1.51-60

Abstract

Hepatitis B is a global health problem. Health workers are at high risk for hepatitis B infection. Among health workers, nursing students are at high risk for hepatitis B infection. One of the prevention efforts against hepatitis B infection is vaccination. Nursing students are the group that must be prioritized for vaccines. However, in Indonesia there is no mandatory policy for health workers to be vaccinated against hepatitis B, especially nursing students. The implementation of self-vaccination is determined by the behavior of nursing students. This study aimed to describe the knowledge, attitudes and actions of students of the Professional Nursing Study Program at the University of Riau towards hepatitis B vaccination. The study was conducted with a cross-sectional design. About 83 respondents were involved in this study, using a simple random sampling technique taken based on inclusion and exclusion criteria. The instrument used is a questionnaire that has been tested for validation and reliability. The results showed 53% respondents had a good knowledge, 63,9% had a positive attitude and 51,8% respondents had carried out hepatitis B vaccination. Statistical analysis using Kolmogorov-Smirnov test showed there were significant difference between knowledge and attitude (p=1,000) or knowledge and action (p=1,000). In can be concluded that there were no significant association between knowledge and attitude or knowledge and action toward hepatitis B vaccination among students of Nurse Study Program University of Riau.
Pengaruh Ekstrak Buah Bakau (Rhizophora sp) terhadap Ekspresi Monocyte Chemoattractant Protein-1 pada Aorta Tikus Aterosklerosis Muhammad Yulis Hamidy; Huriatul Masdar; Ayu Trisya Arti
Jurnal Ilmu Kedokteran Vol 17, No 1 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i1.2023.41-45

Abstract

Atherosclerosis is an atheromatous plaque that protrudes into and clogs blood vessels. This study aimed to analyze the effect of Rhizophora sp extract on the expression of Monocyte Chemoattractant Protein-1 (MCP-1) in the early stages of atherosclerosis in rats fed an atherogenic diet. Eighteen abdominal aortic paraffin blocks of white rats were used, consisting of 3 groups: normal diet (K1), atherogenic diet (K2), and atherogenic diet and Rhizophora sp extract (K3). The effect of Rhizophora sp extract was assessed by immunohistochemical examination. MCP-1 expression was calculated in 5 fields of view, then analyzed using Photoshop Image Analysis. The results of this study indicated that administration of Rhizophora sp extract reduced MCP-1 expression in K3 compared to K2 (0.155±0.075 vs 0.246±0.097) although this result was not statistically significant. In conclusion, Rhizophora sp extract has the ability to inhibit MCP-1 expression in the aorta of rats fed an atherogenic diet.
Peningkatkan Peran Masyarakat Dalam Deteksi Dini Dan Pencegahan Penyakit Kardiovaskuler Di Wilayah Kerja Puskesmas Purnama Kota Dumai Muhammad Yulis Hamidy; Huriatul Masdar; Fifia Chandra
Jurnal Pengabdian UntukMu NegeRI Vol 7 No 2 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

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Abstract

Tingginya angka kejadian dan kematian akibat penyakit kardiovaskuler masih menjadi masalah kesehatan utama, termasuk di Kota Dumai. Kader posyandu sebagai perpanjangan tangan pemerintah sangat berperan dalam membantu mendeteksi dini adanya risiko penyakit kardiovaskuler ini. Tujuan dari kegiatan pengabdian kepada masyrakat ini adalah untuk meningkatkan pengetahuan dan keterampilan kader posyandu dalam melakukan deteksi dini serta memberikan edukasi kepada masyarakat tentang pencegahan risiko terjadinya penyakit kardiovaskuler. Kegiatan ini dilaksanakan dalam bentuk ceramah dan pelatihan keterampilan pengukuran antropometri dan tekanan darah dengan melibatkan 20 orang kader posyandu lansia yang ada di wilayah kerja Puskesmas Purnama Kota Dumai. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan kader mengenai penyakit kardiovaskuler, risiko serta pencegahannya. Selain itu, keterampilan kader dalam melakukan pengukuran antropometri dan interpretasinya serta melakukan pengukuran tekanan darah juga sudah baik. Dengan demikian diharapkan setelah pelatihan ini kader sudah mampu melakukan deteksi dini adanya risiko penyakit kardiovaskuler pada masyarakat setempat.
Ketebalan Tunika Media Aorta Tikus Aterosklerosis Pasca Pemberian Ekstrak Buah Bakau (Rhizophora sp) Muhammad Yulis Hamidy; Huriatul Masdar; Adham Alfian
Jurnal Ilmu Kedokteran Vol 17, No 2 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i2.2023.117-120

Abstract

Atherosclerosis is a multifocal immunoinflammatory disease of medium and large arteries stimulated by lipids, endothelial cells, leukocytes and intima smooth muscle cells. One of the markers of atherosclerosis is thickening of the tunica media. The administration of antioxidants is expected to inhibit the occurrence of atherosclerosis. Mangrove (Rhizophora sp) is one of plants with a high source of antioxidants. The objective of this study was to analyze the effect of mangrove (Rhizophora sp) fruit extract on the thickness of aortic tunica media of atherosclerotic rats. A total of eighteen rats were used in this study, divided into 3 groups. Group A (standard control) is a group of rats that received a standard diet. Group B (positive control) is a group of rats that received a high cholesterol diet for 3 days. Group C (treatment group), apart from receiving a high cholesterol diet, was also given Rhizophora sp fruit extract at a dose 500 mg/kg b.w/day orally for 3 days. The effect of mangrove (Rhizophora sp) fruit extract on the thickness of the aortic tunica media was evaluated by a histological procedure using the Leica application. This study shows that the thickness of aortic tunica media is higher in the group receiving a high cholesterol diet than the standard control group (0.096 vs. 0.079; P=0.036). The group that received mangrove (Rhizophora sp) fruit extract had relatively the same thickness as the standard group (0.080 vs. 0.079; P=0.999). As the conclusion, Mangrove (Rhizophora sp) fruit extract may inhibit thickening of the aortic tunica media in atherosclerotic rats.