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Perbandingan Nilai Risk Malignancy Index Kanker Ovarium Tipe Serosum dan Musinosum RSUP Dr. M. Djamil Padang pada Tahun 2017 Frita Dwi Luhuria; Defrin Defrin; Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.87-94.2020

Abstract

The Risk Malignancy Index (RMI) is one of the simplest assessments that can assist in diagnosing and determining the prognosis of benign and malignant adnexa masses. Epithelial carcinoma is the most common type of about 90% of ovarian cancers.  As many as 35-40% of the epithelial type are serous and 6-10% are musinosum.This study aims to compare the picture of RMI value on the incidence of ovarian cancer serosum and musinosum type. This study was cross sectinal comparative study from medical records of ovarian cancer patients at obstetrics and gynecology section in DR M Djamil Hospital Padang from January 1st, 2017 until December 31st, 2017. The population was found one hundred and forty of patients with ovarian cancer and only one hundred and twenty nine of patients met the inclusion criteria and there were no exclusion criteria. Next RMI value is calculated based on RMI 1 formula, result is described in tabular form and data processing with SPSS program. Conclucion of this study is there were no differences in age distribution, ascites occurrence and age of menopause in serous and musinosum ovarian cancer. There is a difference in Ca, 125 levels in serous with musinosum ovarian cancer which also contribute to the high value of RMI. The mean value of patients‘s RMI in serous type ovarian cancer is higher than the mean value of RMI in patients with type Musinosum ovarian cancer. Keywords: index of risk malignancy, menopause, ultrasonography, anatomic pathology, serous ovarian carcinoma
Gambaran Hasil HPV Test dengan PAP Test pada Pasien dengan Lesi Prakanker Serviks di RSUP Dr M Djamil Padang Angga Trifianda Prima; Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 2, No 2 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.2.83-86.2018

Abstract

Objective: To determine the description of the HPV Test results with the PAP Test in patients with cervical precancerous lesions at Dr. M. Djamil Padang.Methods: This study used a descriptive method with a sample of all patients with cervical precancerous lesions who had the HPV test and PAP test results in Dr. M. Djamil Padang from January 1, 2015 - December 31, 2017. Data were taken from the patient's medical records, including diagnosis, PAP test results using the Hybrid Capture (HC) method, and HPV test. Results: During the study period, 80 patients had PAP test results leading to precancerous lesions and cervical cancer. Of the 80 patients, only 4 cases with positive HPV test results. Conclusion: In this study, there were many cervical precancerous lesions with negative HPV test results.Keywords: Cervical precancerous lesions, PAP test, the HPV test
Colposcopy Findings In High-Grade Cervical Precancer Lesion Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 4, No 2 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.194-202.2020

Abstract

Cervical precancer lesion can generally be seen in the transformation zone. Colposcopy allows us to see an image of enlarge precancer lesion in the transformation zone. The colpocopist should consider some important things to determine the appearance of low-grade lesion or high-grade lesion. Two important things are the description of abnormal epithelium and the description of abnormal blood vessels. The description of the abnormal epithelial seen after administration of acetic acid 3-5%,  acetowhite looks faster and disappears slower. The “white” lesion is more concentrated like the color of shells, with clear border and surface contour. To find the abnormal blood vessels more clearly, we can use the green filter. High-grade lesion shows rough mosaic and rough punctation or both. In addition, finding the cervical blood vessels can help us to determine high-grade lesion. By understanding the description of the epithelial cervix and abnormal blood vessels , we will easily distinguish high-grade lesions from low grade lesion.  Keywords: cervical precancer, colposcopy findings
Peran Ultrasonografi dalam Evaluasi Pasca Operasi Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.1-6.2020

Abstract

The role of ultrasonography (USG) in postoperative gynecology is to assess and evaluate postoperative complications. Ultrasonography are the methods which is noninvasive hence minimize the risk during examination and decrease discomfort the patients. In this literature review, we will explain three main topic role of ultrasound to evaluate postoperative condition such as hematoma, injuries due to the urinary tract and residive mass especially for gynecology oncology cases. Hematoma divided into hematoma on the stump of (the vault is hematoma) and subfascial hematoma. The use of ultrasonography also to evaluate injuries at organ of the urinary tract, especially kidney and ureters. There are two methods which are transabdominally and transvaginally to evaluate the ejection of urine that can confirm that there are no obstruction in the ureter. In addition there is a ultrasound can be used to assess hydronephrosis. In cases of cancer, ultrasound can be used to evaluate residive mass in upper abdomen such as peritoneum (peritoneal carcinomatosis) and liver metastases. Keywords: ultrasonography, hematoma, hydronephrosis, residive mass
Diagnostic Test On Modified Score Of Cesarean Section History In Placenta Accreta Index In Predicting Placenta Accreta Diagnosis In Rsup Dr M Djamil Widayat Widayat; Andi Friadi; Hafni Bacthiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.215-230.2021

Abstract

Introduction : Placenta accreta is defined as abnormal implantation of placenta villi which invades myometrium without the presence of decidua bacalis resulting in placenta that is difficult to remove. Based on the depth of invasion, placenta accreta is divided into three grades, placenta accreta, placenta increta, and placenta percreta. Placenta accreta developes if chorionic villi attaches to endometrium beyond desidua basalis. Placenta increta develops when chorionic villi invades the whole myometrium. Placenta percreta developes when chorionic villi attaches beyond myometrium reaching serous and abdominal organ. Based on clinical manifestation, placenta accreta is the common term being used. Incident of abnormal placenta invasion varies from 1 : 93.000 up to 1 : 540 pregnancy. PA incidence had increased four times from 1994 to 2002 in line with increased of caesarean section procedure. Other study showed history of caesarean section increased risk of placenta accreta up to 8,7 times. Placenta accreta index (PAI) was developed based on scoring process or various parameters assessment to help diagnose placenta accreta. The parameters including: history of caesarean section ≥ 2 times, lacunae grade, sagittal smallest myometrial thickness, anterior placenta previa and birding vessel. High PAI indicates high risk of abnormal placenta invasion based on histology.Objective : This study aims to investigate modified history of cesarean section score in placenta accreta index in predicting placenta accreta diagnosis in RSUP DR M  Djamil Padang.Material and methods : This was analytical study with cross sectional design. Study population was 84 placenta accreta patients in RSUP Dr. M. Djamil Padang from 2016 to 2019. Study sample was recruited using simple random sampling technique after meeting inclusion and exclusion criteria. Statistic analysis was done using Cohen’s Kappa test. Diagnostic test including sensiticivy, specivicity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy.Result : Strenght of agreement diagnosis placenta accreta based on PAI showed Kappa score of -0,002 (Kappa score < 0,2) which indicated  poor strength of agreement. Strenght of agreement diagnosis placenta accreta based on modified PAI showed Kappa score of 0,353 (Kappa score range from 0,21 to 0,40) which indicated fair strength of agreement. PAI diagnostic test yield sensitivity of 97,1%, specificity of 2,8%, positive predictive value of 48,5%, negative predictive value of 50%, and accuracy of 48,6%. Modified PAI diagnostic test yield sensitivity of 97,1%, specificity of 38,9%, positive predictive value of 60%, negative predictive value of 93,3%, and accuracy of 67,1%.Conclusion : PAI has high sensitivity, low specificity, moderate positive predictive value, moderate negative predictive value, and moderate accuration. Modified PAI has high sensitivity, moderate specificity, moderate positive predictive value, high negative predictive value, and high accuracy. PAI diagnosis has poor strength of agreement compared with pathology anatomy. Modified PAI diagnosis has fair strength of agreement compared with pathology anatomy. Modified PAI has identical sensitivity with standard PAI, meanwhile for specificity, positive predictive value, negative predictive value, and accuracy, modified PAI yields higher result compared to PAI.Keywords: Modified score of history caesarean section, placenta accreta index, Modified placenta accreta index, diagnostic test of placenta accreta diagnosis
Perbandingan Akurasi Skor ROMA dan IOTA dalam Prediksi Keganasan Tumor Ovarium Yussya Aulia Malik; Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.70-76.2020

Abstract

Ovarian cancer is the sixth most common cancer found among women. Incidence of ovarian cancer in Dr. M. Djamil Central Hospital had increased from 103 cases to 156 cases in 2011-2012. The Risk Of Ovarian Malignancy Algorithm (ROMA) consists of qualitative serum test where several variables including HE4 serum, CA125 serum, and menopausal status are turned into numerical score (Hye Yon Cho et al 2015). The latest diagnostic modalities developed by International Ovarian Tumour Analysis (IOTA) classifies tumour into four sub groups, based on ultrasound characteristics: unilocular, multilocular, adnexal mass with solid component without papilloma projection, adnexal mass with one or more papilloma projection. Based on this knowledge, author would like to investigate accuracy of ROMA and IOTA score in predicting malignancy status of early ovarian tumour.Objective: Determining ROMA and IOTA so thus can be utilised to predict wether the ovarian tumour is benign or malignant.Method: This was analytical study, with cross sectional design and took place in Obstetrical and Gynaecological Outpatient Clinic of Dr. M. Djamil Central Hospital from August 2016 to January 2019. Sample was recruited using consecutive sampling method. Sixty one participants were recruited with CI 99%. Patients who met inclusion criteria would undergo Ca125 serum test and IOTA score. HE4 level was determined after surgery  and the sample of a tumour was sent to pathology anatomy laboratory of Medical Faculty of Andalas University to investigate the malignancy status. Statistical analysis involved univariate and bivariate test. The variables included frequency distribution, ROMA, and IOTA score. Bivariate analysis included specificity, sensitivity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio.Result: Thirty one patients (50,8%) from peri menopausal group had HE4 level ≤70 pmol/L and 30 patients (49,2%) from post menopause group had HE4 level ≤140 pmol/L. Eleven patients (18%) had CA125 level <35 and 50 patients (82%) had CA125 level ≥35. ROMA index showed low risk in 17 patients (27,9%) and high risk 44 patients (72,1%). IOTA with M Rules was 51 patients (83,6%) and B rules was 10 patients (16,4%). Diagnostic value for ROMA score had sensitivity of 71,9%; RMI of 84,2%; and IOTA 82,5%. ROMA and IOTA accuracy was 68,9% and 92,2%, respectively.Conclusion: IOTA has better sensitivity in predicting ovarian tumour compared with ROMA. ROMA has higher positive predictive value compared with IOTA positive predictive value. ROMA negative predictive value is 5,9%, meanwhile for IOTA it is hard to determineKeywords: ovarian cancer, ROMA, IOTA, Ca-125, HE4
Belief Model (Hbm) of Via on Childbearing Women in Lubuk Buaya Primary Health Centre in 2017 Harridhil Silmi; Andi Friadi; Lisma Evareny
Journal of Midwifery Vol 2, No 1 (2017): Published on June 2017
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.104 KB) | DOI: 10.25077/jom.2.1.35-44.2017

Abstract

Cervical Cancer is the cancer with the second highest rate in Indonesian women and Awareness of childbearing women to Visual Inspection with Acetic Acid (VIA) is still low so often cause death in women. This study aims to determine the Health Beliefs Model (HBM) of VIA on childbearing women in Lubuk Buaya primary health centre 2017.This study was an analytic observational study with cross sectional design, conducted from August - Sept 2017 took 98 respondents as the sample. Data were collected by using questionnaire. Data analysis was performed by using univariate and bivariate.The results showed that there was a significant relationship between education (p=0,001), perceived susceptibility (p=0,000), perceived seriousness (p=0,000), health motivation (p=0,000),  perceived benefits (p=0,000), and perceived barriers (p=0,000), with action cervical cancer early detection with VIA methods. There is a relationship between education, perceived susceptibility, perceived seriousness, health motivation perceived benefits, and perceived barriers to early detection of cervical cancer action with VIA methods on childbearing women in Padang Pasir primary health centre 2017. Suggested to Lubuk Buaya primary health centre to increase further dissemination and health promotion of cervical cancer early detection with VIA method through counseling about the importance of early detection with VIA method.
The Difference of Zinc And Matrix Levels of Metalloproteinase-9 Serum Between Premature Rupture Of Membrane Aterm And Normal Pregnancy Lisa Ernita; Ellyza Nasrul; Andi Friadi
Journal of Midwifery Vol 4, No 1 (2019): Published on June 2019
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (600.944 KB) | DOI: 10.25077/jom.4.1.40-50.2019

Abstract

Premature rupture of membranes (PROM) is one of the common problems in the obstetric field, ranging from 8-10% of term pregnancies will experience PROM. The increase in MMP-9 also has an impact on the degradation of the extracellular matrix and the apoptotic process of amniotic epithelial cells which ultimately leads to membrane rupture. The purpose of this study was to determine the differences in serum zinc and MMP-9 levels between premature rupture of membranes and normal pregnancies.This research is quantitative observational with the cross-sectional design carried out in Independent Practice Midwives for research samples of term premature rupture of normal and amniotic pregnancies, and Biomedical Laboratory of the Medical Faculty of Andalas University in March 2018 to March 2019. The research sample amounted to 35 respondents using consecutive sampling. Zinc and MMP-9 levels were examined by the Human ELISA Kit. Data analysis using the unpaired t-test.The results showed a mean serum zinc level of 13608 ± 1128.976µg / ml in Aterm KPD and 13799,111 ± 1254,335 µg / ml in normal pregnancies with p> 0.05. The mean serum MMP-9 levels were 1682.412 ± 320,398 ng / ml in Aterm PROM and 1807,667 ± 484,735 ng / ml in normal pregnancies with p <0.05.This study concludes that there is no difference in serum zinc levels in premature rupture of membranes and normal pregnancies; there is a difference in MMP-9 levels in premature rupture of membranes and normal pregnancy. 
Perbandingan Uji Hemostasis pada Preeklamsia antara Awitan Dini pada Awitan Lambat Aisah Djumadisstsaniah; Yusrawati Yusrawati; Andi Friadi
Indonesian Journal of Obstetrics & Gynecology Science Volume 3 Nomor 1 Maret 2020
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (717.868 KB) | DOI: 10.24198/obgynia/v3n1.183

Abstract

Tujuan: Penelitian ini bertujuan untuk mengetahui perbandingan uji hemostasis pada preeklamsia antara awitan dini (PEAD) dengan awitan lambat (PEAL)Metode: Penelitian ini adalah penelitian analitik observasional dengan pendekatan potong lintang dengan menggunakan data rekam medis pasien preeklamsia yang dirawat dan atau melahirkan di RSUP DR M Djamil Padang. Analisis univariate disajikan dalam bentuk tabel distribusi frekuensi dan analisis univariate menggunakan uji T tidak berpasangan dan uji Mann-WhitneyHasil: PT (Prothrombine Time) dan APTT (Activated Partial Thromboplastin Time) lebih rendah pada PEAD daripada PEAL (p>0,05), D-dimer lebih tinggi PEAD daripada PEAL(p>0,05), dan jumlah trombosit lebih rendah PEAD daripada PEAL(p<0,05)Kesimpulan: Pada penelitian ini tidak terdapat perbedaan yang bermakna dari parameter faal pembekuan darah berupa PT, APTT, dan D-dimer, tetapi terdapat perbedaan yang bermakna pada jumlah trombosit antara PEAD dan PEAL dengan jumlah trombosit PEAD lebih rendah daripada PEALComparison of Hemostatic Test Result Between Cases of Early and Late Onset PreeclampsiaAbstractObjective: This study aimed to compare haemostatic test of early onset preeclampsia and late onset preeclampsiaMethod: This study was observational analytic study using cross-sectional design that collected data from medical  records patients of preeclampsia who were hospitalized and/or giving birth in RSUP DR M Djamil Padang. Data were analized using Univariate analysis were presented in the form of frequency distribution table and Bivariate data were tested with Independent T-Test and Mann-Whitney TestResult: In this study, there was no differences in prothrombin time, activated partial thromboplastine time and D-dimer but thrombocyte count were different between early and late onset PreeclampsiaConclusion: On this research thrombocyte count is lower in early than late onset Preeclampsia and there is significantly different between early and late onset PreeclampsiaKey words: prothrombin time, activated partial thromboplastin time, D-dimer, thrombocyte count, early and late onset  preeclampsia
Diagnosis Prenatal Hidronefrose dengan Ultrasonografi (laporan kasus) YUSRAWATI YUSRAWATI; ANDI FRIADI
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 1, January 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.294 KB)

Abstract

Tujuan: Melaporkan 2 kasus hidronefrose yang didiagnosis dengan pemeriksaan USG pada masa prenatal. Hasil: Dua kasus hidronefrose yang didiagnosis dengan ultrasonografi. Kasus 1, hidronefrose didiagnosis pada usia kehamilan 32 - 33 minggu, didapatkan jenis kelamin perempuan dengan hidronefrose bilateral. Pada evaluasi postnatal dengan USG didapatkan kesan hidronefrose kanan moderat. Kasus 2, hidronefrose didiagnosis pada usia kehamilan 25 minggu, didapatkan jenis kelamin laki-laki dengan hidronefrose bilateral, megavesika dan oligohidramnion. Persalinan kedua kasus dengan bedah sesar pada kehamilan aterm. Bayi pertama normal. Bayi kedua menderita sindrom Potter dan meninggal setelah 7 jam karena pneumothorax. Kesimpulan: Kelainan yang mengenai ke dua ginjal (bilateral) lebih berbahaya dari pada kelainan yang mengenai satu ginjal (unilateral). [Maj Obstet Ginekol Indones 2007; 31-1: 42-8] Kata kunci: prenatal, hidronefrose, ultrasonografi