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All Journal Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Journal of Midwifery Majalah Kedokteran Andalas UMI Medical Journal Andalas obstetrics and gynecology journal Jurnal Ilmu Keperawatan dan Kebidanan Jurnal Kesehatan Saintika Meditory
Andi Friadi
Universitas Andalas
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Recurrence-Free Survival Stage IB1-IIA2 Intermediate Risk Group (Based on Kartu Delgado) Cervical Carcinoma after Radical Surgery and Adjuvant Radiotherapy: Kesintasan Bebas Kekambuhan Kelompok Risiko Menengah Berdasarkan Kartu Delgado pada Kanker Serviks Stadium IB1-IIA2 Pascaoperasi Radikal dan Radioterapi Ajuvan Andi Friadi; Sigit Purbadi; Budiningsih Siregar; Bambang Sutrisna
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.542 KB) | DOI: 10.32771/inajog.v2i3.397

Abstract

Objective: To evaluate the benefits of adjuvant radiotherapy (ART) based on Kartu Delgado (simple form of Gynecologic Oncology Group (GOG) scoring system) aimed at women with early stage cervical cancer after radical surgery. Method: Fifty patients were enrolled for this study. Twenty one patients from 2011-2012 were given ART following surgery based on their Kartu Delgado score from as follows: score <120 were designated for observation; score >120 were given ART. Their score and recurrence were compared with 29 patients who were treated in 2009-2010 (based on single prognostic factor). Result: We observed eighteen recurrences for the duration this study. Thirteen patients from the period of 2009-2010 and five patients from the period of 2011-2012. Most recurrences occurred in patients from 2009-2010 with score > 120 but were not designated ART. Two-years recurrence-free survival (RFS) for subjects with score <120 who were designated observation was 76.23% while for score >120 with ART was 64.29%. Conclusion: Adjuvant radiotherapy given based on Kartu Delgado reduced the number of recurrences in women with stage IB-IIA cervical cancer after treated by surgery. Keywords: cervical carcinoma, intermediate risk, prognostic factor, radical hysterectomy
PENGARUH PAPARAN ASAP ROKOK TERHADAP KADAR ZINK DAN KORTISOL PADA TIKUS PUTIH HAMIL (RATTUS NORVEGICUS) Rika Armalini; Andi Friadi
Jurnal Ilmu Keperawatan dan Kebidanan Vol 10, No 1 (2019): JURNAL ILMU KEPERAWATAN DAN KEBIDANAN
Publisher : Universitas Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/jikk.v10i1.582

Abstract

Penelitian ini merupakan penelitian Eksperimen dengan desain penelitian post test only control group design Penelitian dilakukan di lab farmasi unand, pada bulan Juni sampai dengan agustus 2018. Pengambilan sampel dilakukan dengan simple random sampling (acak sederhana), Jumlah sampel sebanyak 28 ekor dibagi menjadi 4 kelompok, kelompok 1 sebagai kontrol penelitian, kelompok 2 diberikan perlakuan 1 batang rokok, kelompok 3 diberikan perlakuan 2 batang rokok dan kelompok 4 diberikan perlakuan 3 batang rokok. Pemeriksaan kadar zink dan kadar kortisol dilakukan di Laboratorium Biomedik Universitas Andalas Padang dengan metode ELISA. Tidak terdapat perbedaan bermakna antara paparan rokok dengan kadar zink (p= 0.32) maka, (p > 0,05). Dan tidak terdapat perbedaan paparan asap rokok dengan rerata kadar kortisol (p = 0,146) maka, ( p > 0,05). Kata Kunci: asap rokok, zink, kortisol
HUBUNGAN KADAR KORTISOL DAN PROSTAGLANDIN MATERNAL DENGAN PERSALINAN PRETERM DAN ATERM Fanny Jesica; Andi Friadi
Jurnal Ilmu Keperawatan dan Kebidanan Vol 10, No 1 (2019): JURNAL ILMU KEPERAWATAN DAN KEBIDANAN
Publisher : Universitas Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/jikk.v10i1.540

Abstract

Penelitian ini merupakan penelitian Observasional dengan desain penelitian cross-sectional. Penelitian dilakukan di RSUD dr. Rasidin Padang, RSUD. Prof. Dr. MA Hanafiah SM Batusangkar, RSUP. M. Djamil, dan BPS. Nurhaida, Amd.Keb pada bulan September 2017 sampai Januari 2018. Jumlah sampel sebanyak 50 responden yang dipilih secara consecutive sampling yang dibagi menjadi 2 kelompok. Pemeriksaan kadar kortisol dan prostaglandin dilakukan di Laboratorium Biomedik Universitas Andalas Padang dengan metode ELISA. Terdapat hubungan bermakna antara kadar kortisol dengan persalinan preterm dan aterm (p= 0,02; p < 0,05). Terdapat hubungan kadar prostaglandin dengan persalinan preterm dan aterm (p = 0,023; p < 0,05). Terdapat hubungan kadar kortisol dengan prostaglandin pada aterm (p = 0,0001; p < 0,05). Tidak terdapat hubungan kortisol dan prostaglandin pada preterm (p = 0,52; p > 0,05). Kata Kunci: Kortisol, Prostaglandin, Persalinan Preterm
Hubungan asupan vitamin D dengan kadar 25(OH)D serum pada ibu hamil trimester III etnis minangkabau Athica Oviana; Andi Friadi; Cimi Ilmiawati
Majalah Kedokteran Andalas Vol 42, No 3S (2019): Published in November 2019
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (435.148 KB) | DOI: 10.25077/mka.v42.i3S.p11-18.2019

Abstract

Tujuan: Untuk mengetahui hubungan asupan vitamin D dengan kadar 25(OH)D serum pada ibu hamil trimester III etnis Minangkabau. Metode: Penelitian dengan desain cross-sectional di wilayah kerja Puskesmas Andalas Padang terhadap 88 orang subjek ibu hamil trimester III etnis Minangkabau. Penelitian dilakukan dengan teknik wawancara terstruktur menggunakan kuesioner dan food recall 24 jam selama dua hari dan pemeriksaan kadar 25(OH)D serum dengan metode ELISA. Hasil: Hampir separuh subjek penelitian (n=40; 45,5%) termasuk dalam kategori defisiensi vitamin D (<20 ng/mL). Rerata kadar 25(OH)D serum 23,0±21,0 ng/mL (mean±SD), asupan vitamin D 5,6±4,6 µg/1000 kkal/hari. Uji korelasi Pearson menunjukkan tidak terdapat hubungan antara asupan vitamin D dengan kadar 25(OH)D serum pada ibu hamil trimester III (r=0,161; p=0,134). Simpulan: Tidak terdapat hubungan antara asupan vitamin D dengan kadar 25(OH)D serum pada ibu hamil trimester III etnis Minangkabau.
FAKTOR RESIKO TERJADINYA LESI PRAKANKER SERVIKS MELALUI DETEKSI DINI DENGAN METODE IVA (INSPEKSI VISUAL DENGAN ASAM ASETAT) Tia Reza; Andi Friadi
Jurnal Kesehatan Saintika Meditory Vol 5, No 2 (2022): November 2022
Publisher : STIKES Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jsm.v5i2.1566

Abstract

Kanker leher rahim merupakan masalah kesehatan yang penting bagi wanita. Angka kejadian kanker cerviks terus terjadi peningkatan dari waktu ke waktu. Kanker ini dialami oleh lebih dari 1,4 juta wanita di seluruh dunia. Setiap tahun, lebih dari 460.000 kasus terjadi dan sekitar 231.000 orang meninggal karena penyakit ini. Di Indonesia, berdasarkan data riset kesehatan dasar (riskesdas) tahun 2013, prevalensi tumor/kanker di Indonesia adalah 1,4 per 1000 penduduk. Kanker tertinggi di Indonesia adalah kanker payudara dan kanker leher rahim. Kanker payudara dan kanker leher rahim merupakan jenis kanker tertinggi pada pasien rawat inap maupun rawat jalan di seluruh RS di Indonesia, dengan jumlah pasien sebanyak 12.014 orang (28,7%) untuk kanker payudara, dan kanker leher rahim 5.349 orang (12,8%). Sehingga diperlukan pemeriksaan kanker leher rahim dengan metode IVA yang digunakan untuk mendeteksi kanker secara dini. Tujuan penelitian ini yaitu untuk mengetahui hasil skrining IVA pada perempuan khususnya wanita usia subur yang sudah menikah di Sumatera Barat khususnya di Bukittinggi, Agam, Payakumbuh, dan Pariaman. Desain penelitian ini adalah crosssectional deskriptif analitik. Variabel penelitian ini adalah skrining metode Inspeksi Visual Asam Asetat (IVA) pada wanita yang telah menikah dan umur di atas 25 tahun. Populasi dalam penelitian ini adalah seluruh wanita usia subur yang melakukan pemeriksaan IVA di 4 wilayah tadi. Sampel yang diambil untuk 4 daerah tadi dengan cara total sampling sebanyak 414 responden. Data yang dikumpulkan menggunakan lembar observasi data sekunder dan disajikan dalam tabel distribusi. Hasil penelitian menunjukkan bahwa sebagian besar kategori IVA (+) sebanyak 48 orang dan IVA (-) sebanyak 366 orang.  Skrining menunjukkan sebagian responden dengan kategori IVA (+) dipengaruhi oleh berbagai faktor resiko dari usia, menarch < 12 tahun, usia pertama berhubungan seksual < 17 tahun, sering keputihan, merokok, terpapar asap rokok> 1 jam sehari, sering konsumsi buah dan sayur, makanan berlemak dan berpengawet, kurang aktifitas fisisk, pernah papsmear, sering berganti pasangan, riwayat keluarga kanker, kehamilan pertama > 35 tahun, pernah menyusui, menikah > 1 kali, pemakian KB, paritas, menopause, dan obesitas. Kata Kunci: Deteksi Dini; Faktor Resiko; Inspeksi Visual Asam Astetat (IVA); Skrining
Gambaran Hasil HPV Test dengan PAP Test pada Pasien dengan Lesi Prakanker Serviks di RSUP Dr M Djamil Padang Prima, Angga Trifianda; Friadi, Andi
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 2 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.2.83-86.2018

Abstract

Objective: To determine the description of the HPV Test results with the PAP Test in patients with cervical precancerous lesions at Dr. M. Djamil Padang.Methods: This study used a descriptive method with a sample of all patients with cervical precancerous lesions who had the HPV test and PAP test results in Dr. M. Djamil Padang from January 1, 2015 - December 31, 2017. Data were taken from the patient's medical records, including diagnosis, PAP test results using the Hybrid Capture (HC) method, and HPV test. Results: During the study period, 80 patients had PAP test results leading to precancerous lesions and cervical cancer. Of the 80 patients, only 4 cases with positive HPV test results. Conclusion: In this study, there were many cervical precancerous lesions with negative HPV test results.Keywords: Cervical precancerous lesions, PAP test, the HPV test
TUMOR GANAS OVARIUM RESIDIF METASTASIS KARSINOMA MUSIN KE UMBILIKUS, PERITONEUM, DAN CAIRAN ASITES TANPA DITEMUKAN TANDA KEGANASAN PADA PEMERIKSAAN HISTOPATOLOGIS PASCA OPERATIF SEBELUMNYA Fadillah, Arif; Friadi, Andi
Andalas Obstetrics And Gynecology Journal Vol. 3 No. 2 (2019)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.130-136.2019

Abstract

Background : Malignant ovarian tumor are still the number one cause of death and the second most  of incidents for gynecological malignant tumors. The principles of management of ovarian cancer are the same as the principles of handling other malignant diseases, for the treatment of primary lesions operatively and the handling of potential sites of tumor metastases with chemotherapy. Histopathological examination is still considered a gold standard for diagnosis and definitive treatment of malignant ovarian tumors. If histopathologic results are obtained, then the patient will be planned to undergo postoperative chemotherapy. The mismatch between the preoperative and intraoperative clinical features, and the results of postoperative histopathological examination is a problem in managing cases of ovarian malignant tumors.Objective : Report a case of residive ovarian carcinoma with no appearance of malignancy marker in the previous postoperative histopathological examination.Method : Case reportCase : We report the case of a 45-year-old woman with a history of two previous laparotomy. The first operation was carried out in February 2014 on the indication of an extra ovarian cyst, resulting in the impression of a "Follicular Cysts" based on histopathological examination. The second operation was performed in March 2015, performed surgical staging tumors with an indication of malignant ovarian tumors with clinical metastases, but from histopathological examination it was found that "Cystadenoma Ovarii Muscinosum Multiloculare" and "no visible signs of malignancy", so the patient was not managed with postoperative chemotherapy. In April 2019 patients came with complaints of new mass growth, from CT-Scan and USG investigations there was a suspicious impression of a residive ovarian tumor with metastases into the omentum and massive ascites. On May 16, 2019 an optimal debulking was performed with the findings of residive mass, ascites, and mass metastases in the intra operative peritoneum. From the results of histopathological examination, it was found that "Muscinous Carcinoma with metastases to the umbilicus, peritoneum, and ascitic fluidKeywords: Malignant residive ovarian tumor, mucinous ovarian carcinoma
Peran Ultrasonografi dalam Evaluasi Pasca Operasi Friadi, Andi
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.1-6.2020

Abstract

The role of ultrasonography (USG) in postoperative gynecology is to assess and evaluate postoperative complications. Ultrasonography are the methods which is noninvasive hence minimize the risk during examination and decrease discomfort the patients. In this literature review, we will explain three main topic role of ultrasound to evaluate postoperative condition such as hematoma, injuries due to the urinary tract and residive mass especially for gynecology oncology cases. Hematoma divided into hematoma on the stump of (the vault is hematoma) and subfascial hematoma. The use of ultrasonography also to evaluate injuries at organ of the urinary tract, especially kidney and ureters. There are two methods which are transabdominally and transvaginally to evaluate the ejection of urine that can confirm that there are no obstruction in the ureter. In addition there is a ultrasound can be used to assess hydronephrosis. In cases of cancer, ultrasound can be used to evaluate residive mass in upper abdomen such as peritoneum (peritoneal carcinomatosis) and liver metastases. Keywords: ultrasonography, hematoma, hydronephrosis, residive mass
Perbandingan Akurasi Skor ROMA dan IOTA dalam Prediksi Keganasan Tumor Ovarium Malik, Yussya Aulia; Friadi, Andi
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.70-76.2020

Abstract

Ovarian cancer is the sixth most common cancer found among women. Incidence of ovarian cancer in Dr. M. Djamil Central Hospital had increased from 103 cases to 156 cases in 2011-2012. The Risk Of Ovarian Malignancy Algorithm (ROMA) consists of qualitative serum test where several variables including HE4 serum, CA125 serum, and menopausal status are turned into numerical score (Hye Yon Cho et al 2015). The latest diagnostic modalities developed by International Ovarian Tumour Analysis (IOTA) classifies tumour into four sub groups, based on ultrasound characteristics: unilocular, multilocular, adnexal mass with solid component without papilloma projection, adnexal mass with one or more papilloma projection. Based on this knowledge, author would like to investigate accuracy of ROMA and IOTA score in predicting malignancy status of early ovarian tumour.Objective: Determining ROMA and IOTA so thus can be utilised to predict wether the ovarian tumour is benign or malignant.Method: This was analytical study, with cross sectional design and took place in Obstetrical and Gynaecological Outpatient Clinic of Dr. M. Djamil Central Hospital from August 2016 to January 2019. Sample was recruited using consecutive sampling method. Sixty one participants were recruited with CI 99%. Patients who met inclusion criteria would undergo Ca125 serum test and IOTA score. HE4 level was determined after surgery  and the sample of a tumour was sent to pathology anatomy laboratory of Medical Faculty of Andalas University to investigate the malignancy status. Statistical analysis involved univariate and bivariate test. The variables included frequency distribution, ROMA, and IOTA score. Bivariate analysis included specificity, sensitivity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio.Result: Thirty one patients (50,8%) from peri menopausal group had HE4 level ≤70 pmol/L and 30 patients (49,2%) from post menopause group had HE4 level ≤140 pmol/L. Eleven patients (18%) had CA125 level <35 and 50 patients (82%) had CA125 level ≥35. ROMA index showed low risk in 17 patients (27,9%) and high risk 44 patients (72,1%). IOTA with M Rules was 51 patients (83,6%) and B rules was 10 patients (16,4%). Diagnostic value for ROMA score had sensitivity of 71,9%; RMI of 84,2%; and IOTA 82,5%. ROMA and IOTA accuracy was 68,9% and 92,2%, respectively.Conclusion: IOTA has better sensitivity in predicting ovarian tumour compared with ROMA. ROMA has higher positive predictive value compared with IOTA positive predictive value. ROMA negative predictive value is 5,9%, meanwhile for IOTA it is hard to determineKeywords: ovarian cancer, ROMA, IOTA, Ca-125, HE4
Perbandingan Nilai Risk Malignancy Index Kanker Ovarium Tipe Serosum dan Musinosum RSUP Dr. M. Djamil Padang pada Tahun 2017 Luhuria, Frita Dwi; Defrin, Defrin; Friadi, Andi
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.87-94.2020

Abstract

The Risk Malignancy Index (RMI) is one of the simplest assessments that can assist in diagnosing and determining the prognosis of benign and malignant adnexa masses. Epithelial carcinoma is the most common type of about 90% of ovarian cancers.  As many as 35-40% of the epithelial type are serous and 6-10% are musinosum.This study aims to compare the picture of RMI value on the incidence of ovarian cancer serosum and musinosum type. This study was cross sectinal comparative study from medical records of ovarian cancer patients at obstetrics and gynecology section in DR M Djamil Hospital Padang from January 1st, 2017 until December 31st, 2017. The population was found one hundred and forty of patients with ovarian cancer and only one hundred and twenty nine of patients met the inclusion criteria and there were no exclusion criteria. Next RMI value is calculated based on RMI 1 formula, result is described in tabular form and data processing with SPSS program. Conclucion of this study is there were no differences in age distribution, ascites occurrence and age of menopause in serous and musinosum ovarian cancer. There is a difference in Ca, 125 levels in serous with musinosum ovarian cancer which also contribute to the high value of RMI. The mean value of patients‘s RMI in serous type ovarian cancer is higher than the mean value of RMI in patients with type Musinosum ovarian cancer. Keywords: index of risk malignancy, menopause, ultrasonography, anatomic pathology, serous ovarian carcinoma
Co-Authors . Widayat Aisah Djumadisstsaniah Angga Trifianda Prima Arif Fadillah Arif Fadillah Arni Amir Aswiyanti Asri Athica Oviana Bacthiar, Hafni Bambang Sutrisna Budiningsih Siregar Defrin Defrin Defrin, Defrin Dini Andri Utami Ellyza Nasrul Fanny Jesica Frita Dwi Luhuria Hafni Bacthiar Harridhil Silmi Hera Novianti Ilmiawati, Ilmiawati Jesica, Fanny liana, nana Lisa Ernita Lisma Evareny Luhuria, Frita Dwi Malik, Yussya Aulia Mardiah, Ainal Nana Liana Nizar, RZ Novianti, Hera Prima, Angga Trifianda RZ Nizar Sigit Purbadi Tia Reza Utami, Dini Andri Widayat Widayat Yusrawati Yusrawati Yussya Aulia Malik