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All Journal Jurnal Kedokteran Brawijaya Nexus Kedokteran Klinik Sari Pediatri
Ganung Harsono
Divisi Alergi-Imunologi, Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Indonesia / RSU Cipto Mangunkusumo Jakarta
Health Professions Medicine & Pharmacology

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Hubungan Anemia pada Kehamilan dengan Berat Badan Bayi Lahir di RSUD Dr. Moewardi Damara, Novia; Harsono, Ganung; Suryawan, Arif
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Anemia is a problem in world health which attack a quarter of world population. Pregnancy anemia can caused bad effects to mother or the fetus. This research aims to reveal the relationship between pregnancy anemia and birth weight (high, normal, or low) in RSUD Dr. Moewardi Methods: This study was observational analytic with cross-sectional approach that was conducted in September-October 2012 at the Hospital Dr. Moewardi. The sampling was carried out sampling criterion. The measuring instruments that used were result of laboratory tests in RSUD Dr. Moewardi with cyanmethemoglobin method to determine whether the hemoglobin of pregnant women included in the criteria for anemia and baby scales to measure birth weight. The obtained data were 33 and the data analysis used Chi-Square test with SPSS 17.00 for Windows program. Results: This study demonstrates the value of Chi Square count equal to 33.000, while the value of Chi Square table with α = 0.005 and degrees of freedom (df) = 2 obtained a value 5.99. It means that the value of Chi Square count > value of Chi Square table. Meanwhile, with α = 0.05 shows p = 0.000, which means that p < 0.05. Thus, the two analyzes are the same conclusions that reject H0. Conclusions: There is a relationship between pregnancy anemia and birth weight in Hospital Dr. Moewardi. The samples were pregnant woman who suffer from mild anemia more likely to deliver babies with normal birth weight. Moreover, woman who suffer from severe anemia more likely to deliver babies with low birth weight. Keywords: Anemia, Pregnancy, Weight Birth
Hubungan Pemberian ASI Eksklusif dengan Kejadian Penyakit Alergi pada Anak Wardhani, Annisa; Harsono, Ganung; Widardo, .
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Allergy defined as hipersensitivity reaction started by immunological mechanism through exposure of allergen to atopic individues. Atopy is genetical tendencies to produce IgE that has been exposed to allergen. Allergic disease that commonly found  in children are atopic eczema, asthma bronchial and  allergic rhinitis.  Whereas food allergy and cow’s milk allergy are the first allergic disease that could occur for the first time in children. For the past few years, the incidence of allergic disease is increased rapidly, on domestic and global scale. As the result, the prevention of  this disease become very important. There are many methods has been done, such as exclusive breatfeeding, avoidance of risk factor and tobacco smoke exposure, and probiotic administration, but the result is remain controversial. This study aims to find out the correlation between exclusive breastfeeding and occurence of allergic disease in children. Methods: This is an analytical survey study using case control approach which was conducted on May-July 2013 in Dr. Moewardi Hospital. The sample was taken using purposive sampling and used rule of thumb to take the amount of sample. Occurence of allergic disease is classified as independent variable and exclusive breastfeeding is classified as dependent variable. The children parents that agree to be taken as a sample signed informed consent and filled the questionnaire. The data about diagnosis was required from medical record. 70 samples of research were obtained and analyzed by using Chi Square test followed by the multivariate logistic regression analysis. Results: Bivariat analysis using Chi Square test showed significant correlation between exclusive breastfeeding with the occurence of allergic disease in children with p<0.05. Exclusive breastfeeding Crude OR was 0.351. By using multivariate logistic regression analysis were obtained adjusted OR = 0.214, p = 0.016 (p<0.05), and 95% CI = 0.061-0.751 for independent variable exclusive breastfeeding. Conclusions: There is a significant correlation between exclusive breastfeeding with the occurence of allergic disease in children (p = 0.016). The OR = 0.214 showed that exclusive breastfeeding is a protective factor against allergic disease in children. Keywords: Exclusive Breastfeeding, Allergic Disease, Atopy  
FAKTOR YANG DIDUGA MENJADI RESIKO PADA ANAK DENGAN RINITIS ALERGI DI RSU DR. CIPTO MANGUNKUSUMO JAKARTA Harsono, Ganung; Munasir, Zakiudin; Siregar, Sjawitri P; Suyoko, HEM Dadi; Kumiati, Mia; Evalina, Rita; Palupi, Ratih D
Jurnal Kedokteran Brawijaya Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (114.548 KB) | DOI: 10.21776/ub.jkb.2007.023.03.2

Abstract

This researach was aimed to describe the risk factor profile of pediatric patients with allergic rhinitis. 1792 medical recordsof outpatients pediatric allergy immunology clinic in Cipto Mangunkusumo Hospital from 1997 to 2005. Fifty patients were diagnosed with allergic rhinitis and 22% of them  were having allergic rhinitis with bronchial asthma.Allergic rhinitis were identified higher in boys (62%) than girls (38%) and ranged from 5 months to 13 years and 8 months old. Atopic history were identified in 24 patients (48) while atopic history in patient family were identified in mother (42%), father (40%), and siblings (24%). Total IgE serum increased in 35 patients (88,57%) while total eosinophil serum increased in 28 patients (80%). The most common aeroallergen by skin prick test was house dust mite (36%) and the most common food allergen was shrimp (40%). There were several factors that contribute to the development of allergic rhinitis such as age, sex, family atopic history and increasing in total IgE serum and total eosinophil serum . House dust mite and shrimp were the most common allergen identified in allergic rhinitis. Keywords: allergic rhinitis, risk factors, pediatric
Analisis Hubungan Eosinopenia Terhadap Derajat Keparahan Infeksi COVID-19: Studi Cross-Sectional di Rumah Sakit Umum Daerah Moewardi Surakarta Kesit, Johan Wijaya; Harsono, Ganung; Moelyo, Annang Giri
Sari Pediatri Vol 26, No 2 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.2.2024.102-8

Abstract

Latar belakang. Luaran klinis infeksi COVID-19 pada anak baik tetapi angka kematian COVID-19 masih tinggi. Identifikasi derajat keparahan sedini mungkin dapat memberikan luaran klinis yang baik. Beberapa penanda inflamasi pada kasus COVID-19 salah satunya didapatkan eosinopenia. Tetapi hingga saat ini belum ada penelitian tentang hubungan antara eosinopenia terhadap derajat keparahan infeksi COVID-19 pada anak.Tujuan. Menganalisis hubungan eosinopenia terhadap derajat keparahan infeksi COVID-19 pada anak. Metode. Studi cross sectional observasional analitik, data sekunder retrospektif, diambil dari rekam medis pasien usia 0-<18 tahun terkonfirmasi COVID-19 derajat ringan, sedang, berat dan kritis, yang dirawat diruang isolasi RSUD Dr. Moewardi Jawa Tengah sejak 1 Januari 2022 – 31 Desember 2022 didapatkan 268 subyek penelitian. Analisis statistik SPSS 22 dengan Uji Chi square dan nilai p<0,05 signifikan.Hasil. Dari 268 subyek, kelompok eosinopenia 168 (62,6%) anak dan non eosinopenia 100 (37,4%) anak. Kasus severe (derajat berat dan kritis) 160 (95,2%) anak dan kasus non severe (derajat ringan dan sedang) 8 (4,7%) anak pada kelompok eosinopenia. Ada korelasi bermakna antara eosinopenia terhadap derajat keparahan infeksi COVID-19 kasus severe (p<0,001) dengan nilai duga positif (NDP) 95,2% dan nilai duga negatif (NDN) 87%.Kesimpulan. Eosinopenia dapat memprediksi derajat keparahan infeksi COVID-19 pada anak.
Korelasi antara Penyakit Alergi dengan Kesehatan Mental pada Remaja: Sebuah Studi Observasional di Surakarta Lestari, Dewi Kurnia; Harsono, Ganung; Martuti, Sri
Sari Pediatri Vol 26, No 6 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.6.2025.358-63

Abstract

Latar belakang. Penyakit alergi (atopi) merupakan kondisi hipersensitivitas IgE-mediated yang berkorelasi dengan peningkatan risiko gangguan kesehatan mental pada anak. Studi ini bertujuan menganalisis hubungan antara penyakit alergi dengan gangguan kesehatan mental pada remaja.Tujuan. Menilai korelasi penyakit alergi terhadap gangguan kesehatan mental pada remaja usia 13-18 tahun.Metode. Studi observasional potong lintang dengan consecutive sampling pada 52 siswa SMP Muhammadiyah 4 Surakarta. Diagnosis alergi dinilai menggunakan kuesioner ISAAC Score, sedangkan gangguan kesehatan mental dievaluasi dengan Strengths and Difficulties Questionnaire (SDQ). Analisis statistik menggunakan regresi logistik multivariat.Hasil. Penyakit alergi meningkatkan risiko gangguan kesehatan mental secara signifikan (OR=26,25; IK95%=4,88-141,20; p<0,001). Durasi tidur <8 jam merupakan faktor dominan (OR=54; IK95%=2,80-1041; p=0,008). Variabel lain seperti pendapatan orang tua <UMR (p=0,028) dan status pernikahan orang tua bercerai (p=0,002) juga menunjukkan asosiasi bermakna.Kesimpulan. Penyakit alergi merupakan prediktor kuat gangguan kesehatan mental pada remaja. Intervensi holistik yang mencakup manajemen alergi, optimasi durasi tidur, dan dukungan psikososial diperlukan untuk memitigasi risiko tersebut.
Co-Authors . Widardo Annang Giri Moelyo Arif Suryawan HEM Dadi Suyoko Kesit, Johan Wijaya Lestari, Dewi Kurnia MARIA BINTANG Mia Kumiati Novia Damara Ratih D Palupi Rita Evalina Sjawitri P Siregar Sri Martuti Zakiudin Munasir