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All Journal Sari Pediatri Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Smart Medical Journal Jurnal Gizi Klinik Indonesia Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Maternal and Child Health Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Jurnal Kesehatan Masyarakat

Annang Giri Moelyo

Universitas Sebelas Maret Surakarta

Author-ID : 321150

Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Influence of Body Mass Index, Waist Circumference, and Physical Activity on Age of Menarche in Female Adolescent Rachma, Ulfa Puspita; Moelyo, Annang Giri; Aryani, Imasari
Journal of Maternal and Child Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: The age of menarche which was referred to first time of teenagers had menstruation can be affected by anthropometric index, including body mass index, and waist circumference. Differences in measurement of body mass index, waist circumference, and intensity of physical activity will make some differences in age of menarche. This research aimed to determine the influence of body mass index, waist circumference and physical activity with age of menarche in late adolescent girls in Surakarta. Subjects and Method: The data collected by observed 359 adolescent girls aged 15 until 18 years old in Surakarta during September to October 2016 using observational analytic with cross sectional methods. The independent variables were body mass index, waist circumference, and physical activity. The dependent variable is age of menarche. Body mass index is measured using BW (kg)/BH² (m²) formula, in which: BW is Body Weight (measured using digital standardized scales) and BH is Body Height (measured using standardized microtoise). Students asked to fill in the questionnaire that contain questions regarding reproductive health especially menarche and physical activity questionnaire (IPAQ). The data is processed using SPSS for Windows 23.0 and are analyzed using multiple regression analysis. Results: From the 359 respondents, the mean of age of menarche is 12.6 years (Mean= 12.6; SD= 1). Mean of body mass index is 21.42 kg/m² (Mean= 21.42; SD= 4.44). Mean of waist circumference is 70.41 cm (Mean= 70.41; SD= 7.47). There are 87 respondents (24.2%) with low physical activity, 100 respondents (29.5%) with moderate physical activity, and 166 respondents (46.2%) with high physical activity. Physical activity has significant influence positively (OR= 1.98; 95% CI= 0.39 to 4.72; p= 0.017) on the age of menarche. Conclusion: Physical activity has significant influence on the age of menarche in adolescent girls in Kota Surakarta, Indonesia.

Cortisol levels associated with mortality in children with critical illness: a systematic review Tolibin, Restu Triwulandani; Widiretnani, Septin; Moelyo, Annang Giri
Paediatrica Indonesiana Vol. 63 No. 6 (2023): November 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.6.2023.472-82

Background Critically ill patients, including those with sepsis, have increased cortisol levels due to activation of the hypothalamic-pituitary-adrenal (HPA) axis or critical illness-related corticosteroid insufficiency (CIRCI). Objective To evaluate for a possible association between cortisol levels and mortality from sepsis in pediatric patients by systematic review of the literature. Methods A systematic review was conducted on studies involving critically ill children, including those with sepsis. We included studies published between 2011-2020 analyzing data on cortisol levels (total serum cortisol, serum-free cortisol, salivary cortisol, real-time free cortisol, basal serum cortisol and post-adrenocorticotropin hormone (ACTH) stimulation test, or basal salivary cortisol and post-ACTH stimulation test), the predictive score for mortality (Pediatric Logistic Organ Dysfunction/PELOD), Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality (PIM), Vasotropic Inotropic Score (VIS), or Pediatric Critical Illness Score (PCIS)], mortality (non-survivor percentage), and CIRCI percentage as an outcome in patients with critical illness, sepsis, and septic shock. Results Twenty-one observational studies were included in our systematic review, with a total of 2,212 subjects, 916 of whom had sepsis. Nineteen studies indicated a positive association between elevated cortisol levels and mortality in critically ill children, but 2 studies stated that there was no association with the CIRCI percentage of 32.3 and 84.3% respectively. The mortality percentage of critically ill patients with elevated cortisol levels and sepsis were 25.81 (2.7-60)% and 35.31 (6-60)%, respectively. The percentages of CIRCI in critically ill and sepsis patients were 21.91 (0-84.3)% and 21.35 (0-84.3)%, respectively. Conclusion Cortisol levels may increase or decrease in critically ill children. Elevated cortisol levels are associated with mortality in septic children. The effect of CIRCI on mortality in critically ill children cannot be concluded.

Vitamin D Deficiency is Associated with Hypocalcemia in Preterm Infants Nabiel, Nabiel; Nugroho, Hari Wahyu; Moelyo, Annang Giri
Molecular and Cellular Biomedical Sciences Vol 8, No 2 (2024)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v8i2.473

Background: Vitamin D deficiency results in various problems, like rickets, osteomalacia, heart problems, cancer, diabetes, and autoimmune diseases. Hypocalcemia is a common disorder among preterm infants, indicating vitamin D deficiency. This study was conducted to analyze the association of vitamin D deficiency with hypocalcemia in preterm infants.Materials and methods: A cross-sectional study was performed in preterm infants born in our hospital from December 2022 to May 2023. Venous blood was collected within the first 24 hours to assess vitamin D and calcium levels. Chi-square test and logistic regression analysis were used to assess the association of gestational age, sex, birth weight, and vitamin D with the incidence of hypocalcemia. The significance was determined with p<0.05.Results: There were 40 preterm newborns, comprising 37.5% moderately preterm, 20% very preterm, and 42.5% extremely preterm. Most subjects were female (52.5%). Low birth weight, very low birth weight, and extremely low birth weight occurred in 55%, 27.5%, and 17.5%, respectively. Vitamin D insufficiency and deficiency were observed in 20% and 80% subjects, respectively. Most subjects had hypocalcemia (62.5%). Chi-square test obtained a significant association of vitamin D deficiency with hypocalcemia (p=0.029).Conclusion: Vitamin D deficiency is significantly associated with the incidence of hypocalcemia in preterm infants.Keywords: Vitamin D, hypocalcemia, preterm neonates

Hubungan Durasi Tidur dengan Memori Jangka Pendek pada Siswa Sekolah Dasar Putra, Farras Handyra; Umma, Husnia Auliyatul; Moelyo, Annang Giri
Sari Pediatri Vol 26, No 3 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.3.2024.152-7

Latar belakang. Fungsi tidur secara tepat hingga kini masih belum jelas, tetapi dipercaya bahwa kekurangan durasi tidur dapat menurunkan kinerja kognitif memori jangka pendek. Namun, hasil beberapa penelitian yang sudah dilaksanakan tidak sejalan dengan teori tersebut. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara durasi tidur dan memori jangka pendek, dengan harapan mendapatkan hasil yang baru dan signifikan yang sejalan dengan teori yang sudah ada.Tujuan. Mengetahui hubungan antara durasi tidur dengan memori jangka pendek pada siswa SD Al-Islam 2 Jamsaren Surakarta.Metode. Penelitian ini menggunakan studi analitik cross-sectional dengan sampel siswa tingkat sekolah dasar kelas 4-6 SD Al-Islam 2 Jamsaren Surakarta. Instrumen yang digunakan adalah kuesioner SDSC untuk mengetahui durasi tidur dan tes FDST untuk menentukan kualitas memori jangka pendek anak. Teknik analisis yang digunakan adalah uji analisis chi-square dan uji multivariat regresi logistik. Jika pada analisis bivariat terdapat lebih dari 1 variabel bebas/perancu yang signifikan (p<0.25), maka dilanjutkan dengan analisis multivariat. Tes yang digunakan dalam penelitian ini adalah regresi logistik dengan signifikansi statistik p<0,05. Hasil. Hasil uji bivariat yang signifikan (p<0,05) didapatkan pada uji chi-square durasi tidur dengan memori jangka pendek.Kesimpulan. Terdapat hubungan antara durasi tidur dengan memori jangka pendek pada siswa tingkat sekolah dasar.

Tri-ponderal mass index vs. body mass index to determine obesity and central obesity in adolescents Moelyo, Annang Giri; Ferdian, Hanum
Paediatrica Indonesiana Vol. 64 No. 6 (2024): November 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.6.2024.501-8

Background Tri-ponderal mass index (TMI) is as accurate as body mass index (BMI) in predicting body fat in children and adolescents. Despite TMI simplicity, there have been few studies comparing the sensitivity and specificity of TMI and BMI in determining obesity and central obesity in adolescents. Objective To compare the sensitivity and specificity of TMI and BMI in determining general obesity and central obesity in adolescents. Methods This cross-sectional study was conducted in Surakarta. Healthy school children aged 12 to 17 years underwent TMI, BMI, and waist circumference measurements in 2016, 2017, 2019. Tri-ponderal mass index was calculated as the weight divided by the height in metres cubed (kg/m3). General obesity was defined by the International Obesity Task Force (IOTF) classification of overweight-obese. The BMI-WHO overweight/obesity was defined as over the 85th percentile of the BMI SDS (WHO growth reference). Central obesity was defined as waist-to-height ratio (WtHR) ? 0.5. The sensitivity and specificity of TMI and BMI were calculated. Results A total of 1,173 children and adolescents (837 girls, 336 boys) aged 12-17 years were recruited into this study. The overall prevalences of obesity by BMI-WHO, TMI, BMI-IOTF, and WtHR were 22.68%, 14.92%, 20.55%, and 32.74%, respectively. The sensitivity of BMI-WHO vs. TMI for general obesity was 100.00% vs. 77.71%, respectively (girls) and 100.00% vs. 59.52%, respectively (boys). The specificity was 98.24% vs. 99.56%, respectively (girls) and 98.84% vs. 100%, respectively (boys). The sensitivity of BMI-WHO vs. TMI for central obesity was 58.77% vs 48.82%, respectively (girls), and 47.40% vs 27.75%, respectively (boys). The specificity was 92.81% vs. 96.49%, respectively (girls), and 90.80% vs 98.77%, respectively (boys). Conclusion Tri-ponderal mass index consistently showed higher specificity and lower sensitivity than BMI in assessing general and central obesity.

Identifying competency gaps in intra- and post-learning of a pediatric residency program: a qualitative study Putra, David Anggara; Sekarhandini, Pitra; Moelyo, Annang Giri
Paediatrica Indonesiana Vol. 64 No. 6 (2024): November 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.6.2024.527-35

Background The purpose of the pediatric residency program is for aspiring pediatricians to develop the core competencies needed to care for the children’s health. Upon graduation, pediatricians encounter competency challenges related to diverse populations, cultures, and medical facilities across the nation. Enhancing the efficacy and efficiency of medical education in pediatric residency programs requires identifying and addressing gaps in the post-learning outcomes and intra-learning processes. Objective To investigate competency gaps between the core competencies taught in the pediatric residency training program and the actual necessitates in the professional experience of pediatricians. Methods This qualitative study was conducted by a focus group discussion using semi-constructed questions. Twelve pediatricians who graduated from the Pediatric Residency Program of Universitas Sebelas Maret and had professional work experience of 3 to 18 months were included. Focus group discussions were held online and moderated by the research team using guided questions. Two FGD sessions of 5 and 7 subjects each were conducted. The discussions were recorded and transcribed for analysis in a stepwise manner involving data grouping, information labeling, and data coding to identify the main themes. Results All subjects were working in type B, C, and D hospitals in six different provinces at the time of the study. The competency gaps in intra-residency learning domain covered two topics: curriculum content (core competencies, medicolegal education, effective communication, vaccination, and longitudinal case management) and training (case variations, patient complexity, and affiliated hospital rotations). The smallest competency gaps was core competency; and there was a need for improvement in other topics, particularly in effective communication and vaccination. The competency gaps in the post-learning domain included 4 topics: daily practices (demographic differences, popular topics, and effective communication), health facilities (the gap between individual competency and availability of health facilities), professional relationships with senior/other center colleagues, and strategic plans (continuing medical education). The cultural social background of the population and limited health resources were the main issues in the post-learning are-sxa that need be acknowledged. Effective communication was the theme that emerged and should be to be taught in both ares of learning and post-learning. Conclusion Pediatric residency graduates should address some gaps in learning after completing the pediatric residency program. Effective communication was identified as a learning gap during and after training. Based on our findings, we recommend for the program to provide additional steps to prepare pediatric residents before their graduation.

Central Obesity in Children and Adolescent: Current Themes and Future Potential Researches Moelyo, Annang Giri; Ferdian, Hanum; Wiyono, Nanang
Jurnal Kesehatan Masyarakat Vol. 20 No. 4 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v20i4.2898

The increasing prevalence of central obesity among children and adolescents is a significant concern for public health, as it can lead to various health risks and complications. This study aimed to provide comprehensive updates using the keywords “central obesity,” and “children” or “adolescent”. The Scopus electronic database was searched for relevant articles to compile the basic publishing and citation data found in the article’s title, abstract, and keyword. The author, country, journal, and keyword networks were visualized using the bibliometric software program VOSviewer and biblioshiny. Of 1,190 articles, this study suggests the growth advancement with a 7.84% annual growth rate. The Plos One is the most international publication. The United States is the country leading in this topic. We find four theme clusters: obesity, central obesity, metabolic syndrome, and adolescents. The analysis shows that the diagnosis through anthropometric measurements, body fat assessment, metabolic syndrome, and complications were the major well-known research. The growing interest and future interest topics were waist-to-hip ratio, waist-to-height ratio, lifestyle, adiposity, and dyslipidemia. This bibliographic study showed the expanding publications of central obesity in children and adolescents and suggested several critical themes for future research.

Mosaic Form of Turner Syndrome Laqif, Abdurahman; Wijayanti, Agung Sari; Moelyo, Annang Giri; Budihastuti, Uki Retno; Melinawati, Eriana
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 1 January 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i1.1826

Objective: To report a case of breast growth disorder in a mosaic form of Turner Syndrome. Turner syndrome is a chromosomal condition characterized by small height and primary ovarian insufficiency that affects one in every 2500 female births. Mosaicism is likely to occur when monosomy X develops in only a few cells during development. The clinical presentation of Turner syndrome mosaicism is atypical, with symptom severity varying based on the number of affected cells. This case discusses issues with secondary sex development, including mild hyperandrogenism, and explores how combination hormonal treatment can aid in enhancing secondary sex development. Method: Case Report. Case: A 21-year-old woman presented with chief complaint of the lack of breast enlargement. She exhibited normal genitalia internally and externally and had a regular menstrual cycle. Karyotyping revealed a mosaic pattern of 45, X/46, XX (1 percent/99%) with normal estradiol levels and elevated testosterone levels (indicating mild hyperandrogenism). The patient underwent two cycles of hormone therapy using Ethinyl Estradiol and Drospirenone, resulting in breast growth progression from Tanner stage 1 to Tanner stage 2. Conclusion: Mosaicism in Turner syndrome is plausible, and the severity of clinical symptoms correlates with the number of defective chromosomes. The presentation of Turner syndrome mosaicism varies, and therapy should be tailored to address specific symptoms. While breast development is observed in some girls with Turner Syndrome, instances of breast growth disorder may occur, involving estrogen activity and estrogen receptor sensitivity. Although the exact cause of impaired breast growth remains unknown, administering estrogen in such cases can improve secondary sexual characteristics. Keywords: mild hyperandrogenism, mosaicism, turner syndrome

Tri-ponderal mass index and body mass index for estimating body fat in children in Surakarta, Indonesia Moelyo, Annang Giri; Nisa, Azzahra Fadhlila Aulia; Astuti, Anita Sefti; Mardiyah, Putri Ma’rifatul; Azzainabi, Nur Fatimah Nikmatullah; Kumala, Soebhita Hema; Rahayu, Cynthia Octaviani; Purnata, Lyviana Patrishia; Marcellia, Stefany; Prisola, Steiner Lukas
Jurnal Gizi Klinik Indonesia Vol 18, No 4 (2022): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.91159

Background: The body mass index parameter is currently used to determine obesity (excess body fat) in children. Using this measure has limitations in predicting body fat, particularly in adolescents. An alternative parameter to predict body fat is the tri-ponderal mass index (TMI).Objective: The study aims to investigate the different patterns between body mass index and triponderal mass index in children and to determine the correlation of body mass index (BMI) or TMI as a predictor of body fat.Methods: This cross-sectional study of 351 subjects aged 6-18 in Surakarta (241 females; 110 males). All subjects underwent anthropometric measurements (height and weight) and body fat percentage measurements. We used equations for predicting the percent body fat in boys and girls based on their TMI and BMI.Results: TMI and BMI overall means were 13.3±2.9 vs 20.2±4.7. Among subjects less and more than 12 years, the TMI and BMI means were 13.3±2.1 vs 17.9±3.6. and 13.3±3.1 vs 20.7±4.8. The adjusted R2 of equations for predicting percent body fat based TMI and BMI were 0.76 vs 0.33 in boys and 0.89 vs 0.87 in girls).Conclusions: TMI showed greater stability with age than BMI. TMI was a better predictor for body fat percentage than BMI for both sexes, especially in boys. It is worth considering replacing body mass index with triponderal mass index to estimate body fat percentage in boys.

Analisis Pengaruh Keaktifan Posyandu dan Keanekaragaman Makanan terhadap Status Gizi Balita di Kecamatan Jenawi Pratiwi, Tan Mike; Maulina, Rufidah; Sukamto, Ika Sumiyarsi; Moelyo, Annang Giri
Sari Pediatri Vol 26, No 6 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.6.2025.383-8

Latar belakang. Studi Status Gizi Indonesia tahun 2022 menunjukkan angka stunting di Indonesia mencapai 21,6%. Penimbangan rutin Posyandu dapat mencegah terjadinya gizi buruk. Kebutuhan asupan nutrisi dipenuhi dengan makanan yang beragam.Tujuan. Penelitian ini bertujuan untuk mengetahui hubungan keaktifan Posyandu dan keanekaragaman makanan dengan status gizi balita.Metode. Penelitian ini menggunakan pendekatan cross-sectional. Keanekaragaman makanan diukur dengan Dietary Diversity Score (DDS), kunjungan ke Posyandu didapatkan dari kartu menuju sehat (KMS), sedangkan status gizi didapatkan dari hasil penimbangan. Populasi penelitian meliputi 66 ibu dan balita usia 12-59 bulan di Kecamatan Jenawi. Data dianalisis melalui uji korelasi Rank Spearman dan uji resgresi logistik ordinal dengan nilai alpha 0,05.Hasil. Hasil penelitian menunjukkan mayoritas balita memiliki status gizi normal. Uji bivariat Rank Spearman menunjukkan terdapat hubungan keaktifan Posyandu dengan status gizi balita (p-value 0,003) dan terdapat hubungan keanekaragaman makanan dengan status gizi balita (p-value 0,002). Uji multivariat menunjukkan keaktifan Posyandu dan keanekaragaman makanan mempengaruhi status gizi balita sebesar 27,8%. Uji rasio odds didapatkan peluang tertinggi status gizi buruk yaitu sebesar 41,6 kali pada balita yang memiliki tingkat keanekaragaman makanan dengan kategori kurang.Kesimpulan. Terdapat hubungan antara keaktifan Posyandu dan keanekaragaman makanan dengan status gizi balita. Tenaga kesehatan disarankan untuk mengevaluasi kegiatan Posyandu serta memberikan penyuluhan pentingnya keanekaragaman makanan bagi balita sesuai dengan ketersediaan bahan pangan lokal.

Co-Authors . Widardo Aryani, Imasari Astuti, Anita Sefti Azzainabi, Nur Fatimah Nikmatullah Cahyanto, Erindra Budi Ema Nur Fitriana Eriana Melinawati Ferdian, Hanum Ganung Harsono Hari Wahyu Nugroho Harsono Salimo Husnia Auliyatul Umma, Husnia Auliyatul Ilma Anisa Iskandar, Nurdin Aji Isna Noor Rakhmawati Istar Yuliadi Istar Yuliadi Kesit, Johan Wijaya Kumala, Soebhita Hema Laqif, Abdurahman Marcellia, Stefany Mardiyah, Putri Ma’rifatul Maulina, Rufidah Muhammad Riza Nabiel, Nabiel Nabila Adib Sungkar Nanang Wiyono Nisa, Azzahra Fadhlila Aulia Nurinasari, Hafi Pamungkas, Rafli Yuda Paramasari Dirgahayu Pratiwi, Tan Mike Prisola, Steiner Lukas Purnata, Lyviana Patrishia Putra, David Anggara Putra, Farras Handyra Rachma, Ulfa Puspita Rahayu, Cynthia Octaviani Sekarhandini, Pitra Senyum Indrakila Septin Widiretnani, Septin Soetrisno Soetrisno Suci Murti Karini Sukamto, Ika Sumiyarsi Tolibin, Restu Triwulandani Uki Retno Budihastuti Wijayanti, Agung Sari Zenia Purnama Murti

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