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All Journal Nexus Kedokteran Komunitas Nexus Kedokteran Klinik Sari Pediatri Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Gizi Klinik Indonesia Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Indonesian Journal of Medicine Journal of Maternal and Child Health Jurnal Kesehatan Masyarakat
Annang Giri Moelyo
Universitas Sebelas Maret Surakarta
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Hubungan Status Gizi dengan Rata-Rata Usia Menarche Fitriana, Ema Nur; Moelyo, Annang Giri; Yuliadi, Istar
Nexus Kedokteran Komunitas Vol 1, No 2 (2012): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Menarche is the first menstrual period in woman reproduction cycle. Several epidemiology studies shows that the onset of menarche was became earlier. This condition was supposed to be related with the increases of nutritional status. The aim of this study was to identify the  association between Nutritional status with the mean of age of menarche in SD N 1 Kleco Surakarta (elementary school) students. Method : An analytical observational study using a cross sectional design, was performed in SDN 1 Kleco Surakarta (elementary school) students within the onset of menarche or the 3rd-6th grade’s student on April 2012.  Nutritional status was measured anthropometically for calculating and plotting the body mass index (BMI) for age based on CDC 2000 growth chart. An interview was done to know the age of menarche. The association between nutritional status with the mean age of menarche had been analyzed by Kruskal Wallis SPSS 17 for windows, meanwhile the association between nutritional status with episode of menarche had been analyzed by Chi Square. Result : This study shows 48 (26,8%) subjects were underweight, 96 (53,6%) subject were normal, 25 (13,9%) subject were overweight, and 10 (5,7%) subject were obese.  Twenty six subjects (14.5%) have had period of menarche when we did this study. Means of age of menarche is 10.72 (SD 0.89) years old; the youngest age of menarche is 9 years old (2 subjects, 7.7%). Chi-square test showed no association between nutritional status and episode of age of menarche (odd ratio 1.64, 95%CI 0.63-4.39). Kruskall-Wallis test revealed no association between overweight-obese girls and means of age of menarche (p =0.906,p>0.05). Conclusion : There is no association between nutritional status with the mean of age of menarche in SD Negeri 1 Kleco Surakarta’s student. Keywords: Nutritional Status - Age of Menarche 
Perbedaan Prevalensi Obesitas antara Etnis Jawa, Tionghoa, dan Arab pada Anak Sekolah Menengah Pertama di Surakarta Murti, Zenia Purnama; Moelyo, Annang Giri; Widardo, .
Nexus Kedokteran Komunitas Vol 2, No 3 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background:Obesitycauses many health problems in childhoodsuch ascardiovasculardisease, diabetes, musculoskeletaldisorders, cancersthat causemorbidity and mortalityin adulthood. Ethnicity is a risk factor for obesity. Ethnicity affect eating habits, genetic, amount of energy expenditure, fat distribution and tendency of obese in a child. The aim of this study was to analyze prevalence of obesity in Junior High School Children in Surakarta based on ethnic differences (Javanese, Chinese, and Arabian). Methods:This was a cross-sectional analytic study to 395 students of 8th grade in SMP Negeri 4 Surakarta, SMP Bintang Laut Surakarta, and SMP Diponegoro Surakarta (junior high school) that consist of Javanese, Chinese, and Arabian. Samples were collected by purposive sampling technique. Inclusion criteriaswere students of 8thgrade,parentshave thesameethnicity, and signed an informed consent. Exclusion criterias werechildrenwithedema, have achronicillness, taking medicationlong-termandconditions ofhandicapped.The questionnaire was used to know the ethnic of the child. Body mass index was used to define obesity status with Z-score >+2 SD based on  World Health Organization in 2007 growth chart. Data were analyzed by Chi-Square test. Results:This research shows 246 (63%) subjects were Javanese, 79 (20%) subjects were Chinese, and 70 (17%) subjects were Arabian.  Twenty seven subjects (6.84%) were obese and threehundred andsixty-eight subjects (93.16%) were not obese. Obese prevalence was 4.5 % among Javanese, 8.9 % among Chinese, and 12.9 % among Arabian.It shows a significant differences in the prevalence of obesity among the three ethnics (p=0,036; p < 0.05). Conclusions:There are significant differences in the prevalence of obesity among Javanese, Chinese, and Arabian Ethnic in junior high school children in Surakarta. Keywords:ethnicity, obesity, children
Perbedaan Usia Menarche Siswa SMP Ditinjau dari Etnis Jawa, Tionghoa dan Arab di Surakarta Rakhmawati, Isna Noor; Moelyo, Annang Giri; Karini, Suci Murti
Nexus Kedokteran Komunitas Vol 2, No 3 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background :Menarche is the first menstrual period in woman reproduction cycle. In many studies, race and ethnicity has been shown to contribute to the age of menarche. The objective of thisstudy is to identify the difference of menarche’s agein junior high school girls among Javanese, Chinese and Arabian ethnic in Surakarta. Method :This wasa cross sectional study. Two hundred and thirty healthy Javanese, Chinese and Arabian students from 8th grade of  3 junior high schools in Surakarta were fulfilledthe restriction criteria. Age of menarche and ethnicity of the students were collected through a questionnaire. The difference of menarche’s ageamong those three ethnics were analyzed by Kruskal Wallis in SPSS 17.0 for Windows. Result :Of 230 subjects, 151 (65.65%) students were Javanese, 42 (18.26%) students were Chinese and 37 (16.09%) students were Arabian. Two hundred and fourteen (93.04%) students had recently experienced menarche. The mean age of menarche was 11.9 (SD 0.85) years old and the youngest age of menarche was 9.9 years old. The mean age of menarche in Javanese was 12 years old, in Chinese was 11.8 years old and in Arabian was 11.9 years old. Kruskal Wallis test revealed no significant difference found in the age of menarche among Javanese, Chinese and Arabian (p = 0.567). Conclusion :There is no difference of menarche’s age in junior high school girls among Javanese, Chinese and Arabian ethnic in Surakarta. Keyword :Ethnic,Menarche’s Age  
Hubungan Lama Sakit dengan Status Gizi Anak Penderita Talasemia di RSUD Dr. Moewardi Anisa, Ilma; Riza, Muhammad; Moelyo, Annang Giri
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Systemic complications that occur in children with thalassemia like hepatomegaly, hemosiderosis, bone deformities can affect nutrition disorder and growth retardation. The longer someone has suffered thalassemia, the more likely for the systemic disorder occurred. The aims of this study to find out the correlation between duration of illness with nutritional status of children with thalassemia in Dr. Moewardi Hospital. Methods: This is an observational analytic study using cross sectional design which was conducted from April to May 2013. Thirty children with thalassemia in the Dr. Moewardi Hospital were fulfill the restriction criteria. The duration of illness was acquired from medical record, while the nutritional status was obtained through measurements of weight, height, and the mid-upper arm circumference. The correlation between the duration of illness, gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status was analyzed by using Spearman test followed by the multivariate logistic regression analysis. Results: Spearman test analysis showed no significant correlation between duration of illness with nutritional status in children with thalassemia according to the weight/age and height/age indicator (p = 0,403 and p = 0,408). From the result of analysis on correlation between gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status according to the weight/age and height/age indicator (p > 0,05). Conclusions: There is no significant correlation between the duration of illness with the nutritional status of children with thalassemia according to the weight/age and height/age indicator in Dr. Moewardi Hospital. There is no correlation between gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status. Keywords: Duration of Illness, Nutritional Status, Thalassemia 
Hubungan antara Status Gizi dan Infeksi Blastocystis hominis pada Pasien Bangsal Anak RSUD Dr. Moewardi Surakarta Sungkar, Nabila Adib; Dirgahayu, Paramasari; Moelyo, Annang Giri
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background :Blastocystis hominis is one of the most common protozoans found in worldwide human intestinal tract. In Indonesia, its prevalence reached 60%, the highest prevalence found in children less than 6 years old (25%). Epidemiological and clinical researches show that a defect of nutritional status can inhibit immunity response and increase risk of infectional disease. This study aimed to analyze the correlation between nutritional status and Blastocystis hominis infection among children in RSUD Dr. Moewardi Surakarta. Methods :This study was an observational analytical research using cross-sectional approach. The subjects were every pediatric ward patient in RSUD Dr. Moewardi Surakarta period July-August 2013. A total of 50 subjects were selected using total sampling method. Fresh stool samples were examined using Ziehl-Neelsen staining method. Data were analyzed by multiple logistic regression analysis and processed with the Statistical Product and Service Solutions (SPSS) 17.0 for Windows. Results :Blastocystis hominis was found in 36/50 (72%) stool samples. Poor nutritional status patients in pediatric ward of RSUD Dr. Moewardi Surakarta have the same risk to be infected by Blastocystis hominis compared to good nutritional status patients (OR = 1.04 ; p < 0.97). But children aged under 2 years old have lower risk to get infected by Blastocystis hominis compared to children over 2 years old (OR = 29,333 ; p < 0,001) Conclusion :There is not any significant correlation between nutritional status and Blastocystis hominis infection among children in RSUD Dr. Moewardi Surakarta. Keywords :Blastocystis hominis, nutritional status 
The Relationship between Ferritin and Calcium Levels in Patients with Thalassemia β Major Iskandar, Nurdin Aji; Salimo, Harsono; Moelyo, Annang Giri
Indonesian Journal of Medicine Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Thalassemia is a hereditary disea­se in which the sufferer is unable to produce suf­fi­cient amounts of hemoglobin, causing impaired function of red blood cells and shortened red blood cell age. Thalassemia sufferers are spread all over the world, and thalassemia is one of the health problems in the world. Therapy in patients with thalassemia is with routine blood trans­fusions. One side effect of repeated transfusions is iron overload which causes deposits of iron in the endocrine glands. This study aimed to deter­mine the relationship between ferritin levels with blood calcium levels in patients with β major thalas­semia.Subjects and Method: This was a cross-sec­tional study conducted at Dr. Moewardi, Sura­karta, from June to November 2017. Samples of 49 patients with thalassemia β major aged 5-10 years were selected using consecutive sampling. The dependent variable is blood calcium levels. The independent variable is ferritin level. Data were analyzed with Chi Square test.Results: High ferritin levels reduce calcium level in pediatric thalassemia β major patients, but not statistically significant (OR = 0.27; 95% CI = 0.04 to 1.64; p = 0.134).Conclusion: High ferritin levels decrease with calcium levels in pediatric thalassemia β major patients, but not statistically significant.Keywords: ferritin, calcium, thalassemia β majorCorrespondence: Andhika Trisna Putra. Department of Pediatrics, Faculty of Medicine, Universitas Sebelas Maret/ Dr. Moewardi Hospital, Surakarta. Telpon­/Fax.­0271-633348, Email: andhika.pedia­tric@gmail.­comIndonesian Journal of Medicine (2020), 05(02): 137-141https://doi.org/10.26911/theijmed.2020.05.02.07
Hubungan Status Gizi dengan Rata-Rata Usia Menarche Ema Nur Fitriana; Annang Giri Moelyo; Istar Yuliadi
Nexus Kedokteran Komunitas Vol 1, No 2 (2012): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.224 KB)

Abstract

Background : Menarche is the first menstrual period in woman reproduction cycle. Several epidemiology studies shows that the onset of menarche was became earlier. This condition was supposed to be related with the increases of nutritional status. The aim of this study was to identify the association between Nutritional status with the mean of age of menarche in SD N 1 Kleco Surakarta (elementary school) students. Method : An analytical observational study using a cross sectional design, was performed in SDN 1 Kleco Surakarta (elementary school) students within the onset of menarche or the 3rd-6th grades student on April 2012. Nutritional status was measured anthropometically for calculating and plotting the body mass index (BMI) for age based on CDC 2000 growth chart. An interview was done to know the age of menarche. The association between nutritional status with the mean age of menarche had been analyzed by Kruskal Wallis SPSS 17 for windows, meanwhile the association between nutritional status with episode of menarche had been analyzed by Chi Square. Result : This study shows 48 (26,8%) subjects were underweight, 96 (53,6%) subject were normal, 25 (13,9%) subject were overweight, and 10 (5,7%) subject were obese. Twenty six subjects (14.5%) have had period of menarche when we did this study. Means of age of menarche is 10.72 (SD 0.89) years old; the youngest age of menarche is 9 years old (2 subjects, 7.7%). Chi-square test showed no association between nutritional status and episode of age of menarche (odd ratio 1.64, 95%CI 0.63-4.39). Kruskall-Wallis test revealed no association between overweight-obese girls and means of age of menarche (p =0.906,p>0.05). Conclusion : There is no association between nutritional status with the mean of age of menarche in SD Negeri 1 Kleco Surakartas student. Keywords: Nutritional Status - Age of Menarche
Influence of Body Mass Index, Waist Circumference, and Physical Activity on Age of Menarche in Female Adolescent Rachma, Ulfa Puspita; Moelyo, Annang Giri; Aryani, Imasari
Journal of Maternal and Child Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.509 KB) | DOI: 10.26911/thejmch.2021.06.04.02

Abstract

Background: The age of menarche which was referred to first time of teenagers had men­strua­tion can be affected by anthropometric index, including body mass index, and waist circumference. Differences in measurement of body mass index, waist circumference, and intensity of physical activity will make some differences in age of menarche. This research aimed to determine the influence of body mass index, waist circumference and physical activity with age of menarche in late adolescent girls in Surakarta. Subjects and Method: The data collected by observed 359 adolescent girls aged 15 until 18 years old in Surakarta during September to October 2016 using observational analytic with cross sectional methods. The independent variables were body mass index, waist circum­fe­rence, and physical activity. The dependent variable is age of menarche. Body mass index is measured using BW (kg)/BH² (m²) formula, in which: BW is Body Weight (measured using digital standardized scales) and BH is Body Height (measured using standardized micro­toise). Students asked to fill in the questio­n­naire that contain questions regarding repro­duc­tive health especially menarche and phy­sical activity questionnaire (IPAQ). The data is processed using SPSS for Windows 23.0 and are analyzed using multiple regression analysis. Results: From the 359 respondents, the mean of age of menarche is 12.6 years (Mean= 12.6; SD= 1). Mean of body mass index is 21.42 kg/m² (Mean= 21.42; SD= 4.44). Mean of waist circum­ference is 70.41 cm (Mean= 70.41; SD= 7.47). There are 87 respondents (24.2%) with low physical activity, 100 respondents (29.5%) with mode­rate physical activity, and 166 res­pondents (46.2%) with high physical activity. Physical activity has significant influence posi­tively (OR= 1.98; 95% CI= 0.39 to 4.72; p= 0.017) on the age of menarche. Conclusion: Physical activity has significant influence on the age of menarche in adolescent girls in Kota Surakarta, Indonesia.
Cortisol levels associated with mortality in children with critical illness: a systematic review Tolibin, Restu Triwulandani; Widiretnani, Septin; Moelyo, Annang Giri
Paediatrica Indonesiana Vol. 63 No. 6 (2023): November 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.6.2023.472-82

Abstract

Background Critically ill patients, including those with sepsis, have increased cortisol levels due to activation of the hypothalamic-pituitary-adrenal (HPA) axis or critical illness-related corticosteroid insufficiency (CIRCI). Objective To evaluate for a possible association between cortisol levels and mortality from sepsis in pediatric patients by systematic review of the literature. Methods A systematic review was conducted on studies involving critically ill children, including those with sepsis. We included studies published between 2011-2020 analyzing data on cortisol levels (total serum cortisol, serum-free cortisol, salivary cortisol, real-time free cortisol, basal serum cortisol and post-adrenocorticotropin hormone (ACTH) stimulation test, or basal salivary cortisol and post-ACTH stimulation test), the predictive score for mortality (Pediatric Logistic Organ Dysfunction/PELOD), Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality (PIM), Vasotropic Inotropic Score (VIS), or Pediatric Critical Illness Score (PCIS)], mortality (non-survivor percentage), and CIRCI percentage as an outcome in patients with critical illness, sepsis, and septic shock. Results Twenty-one observational studies were included in our systematic review, with a total of 2,212 subjects, 916 of whom had sepsis. Nineteen studies indicated a positive association between elevated cortisol levels and mortality in critically ill children, but 2 studies stated that there was no association with the CIRCI percentage of 32.3 and 84.3% respectively. The mortality percentage of critically ill patients with elevated cortisol levels and sepsis were 25.81 (2.7-60)% and 35.31 (6-60)%, respectively. The percentages of CIRCI in critically ill and sepsis patients were 21.91 (0-84.3)% and 21.35 (0-84.3)%, respectively. Conclusion Cortisol levels may increase or decrease in critically ill children. Elevated cortisol levels are associated with mortality in septic children. The effect of CIRCI on mortality in critically ill children cannot be concluded.
Vitamin D Deficiency is Associated with Hypocalcemia in Preterm Infants Nabiel, Nabiel; Nugroho, Hari Wahyu; Moelyo, Annang Giri
Molecular and Cellular Biomedical Sciences Vol 8, No 2 (2024)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v8i2.473

Abstract

Background: Vitamin D deficiency results in various problems, like rickets, osteomalacia, heart problems, cancer, diabetes, and autoimmune diseases. Hypocalcemia is a common disorder among preterm infants, indicating vitamin D deficiency. This study was conducted to analyze the association of vitamin D deficiency with hypocalcemia in preterm infants.Materials and methods: A cross-sectional study was performed in preterm infants born in our hospital from December 2022 to May 2023. Venous blood was collected within the first 24 hours to assess vitamin D and calcium levels. Chi-square test and logistic regression analysis were used to assess the association of gestational age, sex, birth weight, and vitamin D with the incidence of hypocalcemia. The significance was determined with p<0.05.Results: There were 40 preterm newborns, comprising 37.5% moderately preterm, 20% very preterm, and 42.5% extremely preterm. Most subjects were female (52.5%). Low birth weight, very low birth weight, and extremely low birth weight occurred in 55%, 27.5%, and 17.5%, respectively. Vitamin D insufficiency and deficiency were observed in 20% and 80% subjects, respectively. Most subjects had hypocalcemia (62.5%). Chi-square test obtained a significant association of vitamin D deficiency with hypocalcemia (p=0.029).Conclusion: Vitamin D deficiency is significantly associated with the incidence of hypocalcemia in preterm infants.Keywords: Vitamin D, hypocalcemia, preterm neonates
Co-Authors . Widardo Aryani, Imasari Astuti, Anita Sefti Azzainabi, Nur Fatimah Nikmatullah Ema Nur Fitriana Eriana Melinawati Ferdian, Hanum Ganung Harsono Hari Wahyu Nugroho Harsono Salimo Husnia Auliyatul Umma, Husnia Auliyatul Ilma Anisa Iskandar, Nurdin Aji Isna Noor Rakhmawati Istar Yuliadi Istar Yuliadi Kesit, Johan Wijaya Kumala, Soebhita Hema Laqif, Abdurahman Marcellia, Stefany Mardiyah, Putri Ma’rifatul Maulina, Rufidah Muhammad Riza Nabiel, Nabiel Nabila Adib Sungkar Nanang Wiyono Nisa, Azzahra Fadhlila Aulia Pamungkas, Rafli Yuda Paramasari Dirgahayu Pratiwi, Tan Mike Prisola, Steiner Lukas Purnata, Lyviana Patrishia Putra, David Anggara Putra, Farras Handyra Rachma, Ulfa Puspita Rahayu, Cynthia Octaviani Sekarhandini, Pitra Septin Widiretnani, Septin Suci Murti Karini Sukamto, Ika Sumiyarsi Tolibin, Restu Triwulandani Uki Retno Budihastuti Wijayanti, Agung Sari Zenia Purnama Murti