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All Journal Jurnal Kesehatan Andalas Jurnal Respirologi Indonesia Majalah Kedokteran Andalas Respiratory Science Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Sains, Teknologi dan Kesehatan
Fenty Anggrainy
Universitas Andalas
Biochemistry, Genetics & Molecular Biology Computer Science & IT Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

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The Effect of Dexamethasone on IL-6 Levels in Confirmed COVID-19 Patients Treated at RSUP Dr. M. Djamil Padang Bobby Hasibuan; Irvan Medison; Fenty Anggrainy
Jurnal Respirologi Indonesia Vol 43, No 3 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i3.426

Abstract

Background: Elevated IL-6 levels have been found in COVID-19 patients and are associated with a poor prognosis. According to COVID-19 management guidelines, several types of corticosteroids can be used as therapy modalities for COVID-19 patients, including dexamethasone, methylprednisolone, and hydrocortisone. The purpose of this study was to examine how dexamethasone administration affected changes in IL-6 levels in confirmed COVID-19 patients at RSUP Dr. M. Djamil Padang.Methods: This was a retrospective cohort study with a sample of all COVID-19 patients who met the inclusion and exclusion criteria and were treated in the COVID-19 isolation ward at RSUP Dr. M. Djamil Padang. The study began in June 2021 and concluded in July 2022. The data was analyzed both descriptively and analytically. The distribution of frequencies and proportions of each variable was included in the univariate analysis. Bivariate analysis employs data-scale-appropriate statistical tests such as the T-test to determine the relationship between independent and dependent variables.Results: The characteristic of the patients were mostly 18-49 years old (37.22%), female (55.67%), of severe clinical degree (49.44%), had no comorbidities (52.78%) and the majority (77.78%) received dexamethasone in the recommended dose (1 x 6 mg). The study's findings revealed that there was no difference in IL-6 values before and after dexamethasone administration in patients with moderate clinical degrees,  but there were differences in IL-6 values before and after dexamethasone administration in patients with severe and critical clinical degrees.Conclusion: The IL-6 level has significantly decreased following dexamethasone administration. Dexamethasone administration causes significant changes in IL-6 values in severe and critical degrees but not in moderate clinical degree.
Hubungan Komorbid dengan Outcome Pasien Terkonfirmasi COVID-19 Di RSUP M. Djamil Padang Tahun 2020 Adiiba Turfha Zahira; Ida Rahmah Burhan; Yusticia Katar; Yuniar Lestari; Fenty Anggrainy; Fathiyyatul Khaira
Majalah Kedokteran Andalas Vol 46, No 10 (2024): Supplementary April 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i10.p1592-1600.2024

Abstract

Tujuan : Penelitian bertujuan Untuk mengetahui hubungan komorbid dengan outcome pasien terkonfirmasi COVID-19 di RSUP. M. Djamil Padang tahun 2020. Metode : Penelitian bersifat analitik observasional dengan pendekatan cross sectional. Data dikumpulkan dan diolah dengan menggunakan teknik total sampling , yaitu semua pasien terkonfirmasi COVID-19 yang dirawat di RSUP M.Djamil Padang berdasarkan kriteria inklusi dan ekslusi . Jumlah sampel penelitian sebanyak 468 pasien terkonfimasi COVID-19 yang dirawat pada periode Maret – Desember 2020. Analisis yang digunakan adalah analisis bivariat berupa Chi-Square . Hasil: Hasil penelitian menunjukkan terdapat hubungan yang signifikan antara komorbid dengan outcome pada pasien terkonfirmasi COVID-19 (p=0,010) di RSUP. M.Djamil Padang. Kesimpulan : Berdasarkan hasil penelitian dapat diartikan bahwa terdapat hubungan antara komorbid dengan outcome pada pasien terkonfirmasi COVID-19.
KARAKTERISTIK PEROKOK DI KALANGAN CIVITAS AKADEMIKA FAKULTAS HUKUM UNIVERSITAS ANDALAS Muhammad Raihan; Fenty Anggrainy; Yuniar Lestari; Miftah Irramah; Yessy Susanty Sabri; Zurayya Fadila
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2026): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v3i2.1957

Abstract

The number of smokers increases every year. It becomes the focus of the Indonesian government’s attention. Through the healthy campus program, the Indonesian Ministry of Health designated Andalas University as one of the pilot campuses, but there are still smokers on campus. Itsn’t just students who smoke, but lecturers and education staff as well. To determine the characteristics of smokers among the academic civility in Faculty of Law, Andalas University. The method used is descriptive observational with quota sampling technique. The sample consisted of 323 students, 18 lecturers, and 5 staff. Data were collected by questionnaire and analyzed with computerized program. The research results showed that 28.9% of the academic civility at Faculty of Law, Andalas University were smokers. The typical average age is 22 years, dominated by men, in general they also have families who smoke. The highest age for starting smoking is 16 years or older. Smokers are dominated by light smokers. The most commonly consumed type of cigarettes is white cigarettes, but 9.5% also use e-cigarettes. The driving force behind smoking behavior usually the social environment. The level of knowledge of academic civility is sufficient category. The conclusion obtained is that there are still smokers among the academic community, so preventive efforts should be made to reduce the number of smokers on campus.
Co-Authors Adiiba Turfha Zahira Afriani Sandra Bobby Hasibuan Bobby Hasibuan Dessy Mizarti Dewi Wahyu Fitrina Dewi Wahyu Fitrina Dwi Rizki Fadhilah Ermayanti, Sabrina Fanny Permata Andriani Fathiyyatul Khaira Hendris Utama Citra Wahyudin Herman, Deddy Ida Rahmah Burhan Ilham Ilham Irvan Medison Irvan Medison Katerine Junaidi Kornelis Aribowo Masrul Basyar Merry Dhama Yanti Miftah Irramah Muhammad Bagus H.S. Muhammad Raihan Oea Khairsyaf Rizki Amrika Sabrina Ermayanti Ulfahimayati Ulfahimayati Yessy Susanty Sabri Yulia Helexandra Yuniar Lestari Yusticia Katar Zurayya Fadila