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All Journal Vegetalika Journal of Mathematical and Fundamental Sciences Jurnal Biologi Universitas Andalas Indonesian Journal of Chemistry JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) Jurnal Mandala Pharmacon Indonesia Jurnal Review Pendidikan dan Pengajaran (JRPP) Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks
Nova Syafni
Fakultas Farmasi, Universitas Andalas
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Ethnobotanical Study of Ferns as Traditional Medicine in Central Siberut, Mentawai Island Nova Syafni; Amri Bakhtiar
Jurnal Biologi Universitas Andalas Vol 10, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jbioua.10.1.10-14.2022

Abstract

West Sumatra Province has two ethnicities, namely Minangkabau and Mentawai. Both ethnicities have the capability to apply plants in folk medicine. This ethnobotanical study was conducted in Saibi Simokop village in three hamlets namely Sirisurak, Simoilaklak, and Saibi. The study was focused on the use of ferns in traditional medicine. Data collection was carried out using the snowball sampling method to seek the traditional healers (sikerei). The results showed that seven species of ferns were used for treatment of fever, inflammation, and poisoning. The ferns were included Cephalomanes javanicum (Blume) Bosch, Angiopteris evecta (G. Forst.) Hoffm., Dicranopteris linearis (Burm. F.) Underw., Diplazium esculentum (Retz.) Sw., Phymatosorus membranifolium (R. Br.) S.G. Lu, Lecanopteris sp., and Asplenium nidus L. The application of ferns in concoctions was administered topically and some were combined with oral administration.
Isolation and Antibacterial Properties of Phenyl Acrylic Acid Derivatives from Balanophora elongata Blume Nanda Putra; Goldha Faroliu; Nova Syafni; Nofrizal; Amri Bakhtiar; Dayar Arbain
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.5

Abstract

Balanophora elongata (Balanophoraceae) is a tropical parasitic flowering plant 9 cm in height. Four known phenyl acrylic acid derivatives, methyl caffeate (1), caffeic acid (2), 1,6-di-O-caffeoyl-β-D-glucopyranose (3), and coniferin (4), were isolated from this plant. Structural elucidation of the isolated compounds was determined by IR, LC-ESI-MS, 1D and 2D NMR.  Extracts and isolated compounds were tested toward some standard human pathogenic bacteria using the agar disk diffusion method. Their inhibition zones were compared to that of chloramphenicol as positive control. Compound 1 showed inhibition toward Streptococcus mutans, while compound 3 and 4 inhibited Staphylococcus aureus.
3,4-DIHYDROXYBENZOIC ACID AND 3,4-DIHYDROXYBENZALDEHYDE FROM THE FERN Trichomanes chinense L.; ISOLATION, ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES Nova Syafni; Deddi Prima Putra; Dayar Arbain
Indonesian Journal of Chemistry Vol 12, No 3 (2012)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.228 KB) | DOI: 10.22146/ijc.21342

Abstract

3,4-dihydroxybenzoic acid (1) and 3,4-dihydroxybenzaldehyde (2) have been isolated from ethyl acetate fraction of methanolic fractions of leaves, stems and roots of the fern Trichomanes chinense L. (Hymenophyllaceae). These two compounds also showed significant antioxidant using DPPH and antimicrobial activities using the disc diffusion assay.
PELATIHAN PEMBUATAN JAMU JAHE MERAH INSTAN DI PASIE JAMBAK KOTA PADANG Nova Syafni; Wiwik Hanifah; Ryan Fajri Kurniawan; Lili Fitriani; Suryati Suryati
Jurnal Hilirisasi IPTEKS Vol 6 No 3 (2023)
Publisher : LPPM Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jhi.v6i3.675

Abstract

The majority of the population in the Pasie Jambak area depends on fishing as their livelihood, which requires them to be in excellent physical condition to carry out their work. Red ginger is one of the most commonly found plants in the market and is known to have benefits in maintaining bodily stamina. Therefore, the Student Executive Board of the Faculty of Pharmacy, Andalas University, in collaboration with faculty members and students, conducted training in the production of instant red ginger herbal drinks with the aim of making it a convenient health beverage for the fishing community, suitable for consumption during their fishing trips. This training was attended by a large number of women residing in the vicinity of Pasie Jambak, Padang City. The training process consisted of several stages. The first stage involved an explanation of the benefits of red ginger, followed by the second stage, which was a practical session on the production of instant red ginger herbal drinks using red ginger rhizomes, sugar, and water. The subsequent stage focused on the packaging of the red ginger product and the proper method of preparing the beverage. The training activities concluded with a discussion session and the completion of questionnaires regarding the implementation of the training. The results of this training demonstrated that the participants were able to smoothly produce and package instant red ginger herbal drinks. The questionnaire results also indicated that overall, all participants were satisfied with the training activities. Therefore, it is expected that this training will provide significant benefits to the community in the Pasie Jambak area, helping to improve their health and offering a practical solution for fishermen who require good physical stamina to carry out their work.
Enhancing Gambir's Economic Value from Processing to Bath Soap Raw Materials: Community Service Program Uswatul Hasanah; Nova Syafni; Adhitya Jessica; Erizal Zaini; Rini Agustin
Warta Pengabdian Andalas Vol 31 No 2 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.2.277-284.2024

Abstract

Gambir, an extract derived from the leaves and branches of the gambir plant, holds significant potential for enhancing the local economy and its benefits as a cosmetics product. Jorong Balai Tampuak Pinang, Nagari Simpang Kapuak, Kecamatan Mungka, was one of the areas producing traditional gambir in Lima Puluh Kota district, West Sumatra, Indonesia. This community service initiative aimed to augment the economic value of gambir from its processing to raw materials of bath soap. The initiative began with an educational session for training participants, outlining the advantages of gambir in skincare and how to incorporate it into bath soap formulations. Following the learning session, participants actively produced gambir-contained bath soap utilizing the provided formula. The activity received favorable feedback from participants who appreciated enhancing knowledge and skills. The outcomes of this endeavor underscore the substantial potential of developing body care products utilizing gambir as a primary ingredient. Participant testimonials underscore the need to conduct similar community engagement activities to harness Gambir's further utilization of other personal care products. The collaboration between the pharmacy study program and the local community has opened new avenues for local economic development and sustainable growth, significantly impacting the local population's well-being in the region.
Body Mist-Making Training and Socialization of Cosmetic Product Registration and Marketing Authorization to Youth Organisations in Kerinci Nova Syafni; Try Andy Sahputra; Saafrida Saafrida; Uswatul Hasanah; Rini Agustin; Rahmi Yosmar; Friardi Ismed; Erizal Zaini
Warta Pengabdian Andalas Vol 31 No 2 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.2.336-342.2024

Abstract

Indonesia is an important country that produces essential oils that are widely used in fragrance cosmetic products. The use of local essential oils for cosmetics needs to be introduced to the youth generation with the aim that they do not just become consumers. Youth organisations in Kerinci have many activities to improve their skills and abilities for a better future. Collaboration between the university and the youth organisation was achieved by providing training on doing cosmetic product training on making cosmetic products. The product uses essential oils called body mist. Nowadays, the youth still know very little about the manufacturing process of cosmetics products. To provide further benefits, this community service activity collaborated with BBPOM in Padang, West Sumatra, to explain cosmetic safety and the registration process of cosmetic products. With this series topic in this training and outreach-related cosmetics, it is hoped that it can increase business ideas for young people who are members of the Sakti Alam Kerinci Organisation.
Formulation of Anti-Blackhead Rubber Mask from Purified Gambier (Uncaria gambir [Hunter] Roxb.) Rini Agustin; Hafizatul Akrami; Nova Syafni
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.340-347.2023

Abstract

The purified was isolated from  Uncaria gambir [Hunter] Roxb. that contains more than 90% of catechins. Its antioksidant  and antibacterial properties have  potential to  formulate  as cosmetics. Dry form formulation of cosmetic was one approach to minimize cathecins degradation in a product.  In this study, three formulation of rubber mask containing 5% of purified gambier was done. . Each formulation was formulated with calcium sulfate, propylene glycol, magnesium carbonate, citrus essential oil and variation of HPMC and chitosan as film former. The three formulas had  a brown color, smooth textures, the gambier odor, visually homogeneous, particle sizes at 112.24 – 116.39 µm, moisture values at 3.9 – 7.04%, pH of 6, drying times of 8 to 15 minutes, adhesive power of > 10 seconds and remained stable for 21 days at 4±2°C and 27±2°C. The actual catechin content in formula I, II, and III were 0.89%, 1.09%, and 1.39%, respectively. The best formula was formula III, which contained 40% HPMC and 10% chitosan due to the fastest drying time of 8.36 minutes ± 19 seconds and the highest catechins content at 1.39%.The purified was isolated from  Uncaria gambir [Hunter] Roxb. that contains more than 90% of catechins. Its antioksidant  and antibacterial properties have  potential to  formulate  as cosmetics. Dry form formulation of cosmetic was one approach to minimize cathecins degradation in a product.  In this study, three formulation of rubber mask containing 5% of purified gambier was done. . Each formulation was formulated with calcium sulfate, propylene glycol, magnesium carbonate, citrus essential oil and variation of HPMC and chitosan as film former. The three formulas had  a brown color, smooth textures, the gambier odor, visually homogeneous, particle sizes at 112.24 – 116.39 µm, moisture values at 3.9 – 7.04%, pH of 6, drying times of 8 to 15 minutes, adhesive power of > 10 seconds and remained stable for 21 days at 4±2°C and 27±2°C. The actual catechin content in formula I, II, and III were 0.89%, 1.09%, and 1.39%, respectively. The best formula was formula III, which contained 40% HPMC and 10% chitosan due to the fastest drying time of 8.36 minutes ± 19 seconds and the highest catechins content at 1.39%.
Inhibition of Edible Plant Torch Ginger (Etlingera elatior (Jack) R. M. Sm.) against α-Glucosidase and α-Amylase Nova Syafni; Athallah Fakhriadi; Nofrizal Nofrizal; Friardi Ismed; Deddi Prima Putra
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.348-352.2023

Abstract

Indonesia's diabetes cases were in the top ten list globally, with 90% of the patients being type-2 diabetes mellitus (T2DM).  An approach for screening the local edible plants is made for managing or treating T2DM by inhibiting α-glucosidase and α-amylase enzymes. Results showed that inflorescence of Etlingera elatior inhibition toward both enzymes. TLC-autography and IC50 value of fractions from E. elatior were used to identify the potential fractions and possible compounds for the activity. The non-polar fraction was spotted in the active substances based on TLC-autography. Then, the targeted compounds were separated by column chromatography to obtain stigmasterol as one of the active compounds. The IC50 values of total extract, n-hexane, EtOAc, BuOH, and isolated compound against α-glucosidase were 16.0, 7.5, 13.5, 9.7, and 2.0 ppm, respectively. The IC50 values for α-amylase inhibition were respectively 88.6, 48.6, 23.2, 29.1, and 27.5 ppm. The positive control (acarbose) against α-glucosidase and amylase exhibited IC50 values of 153.2 and 12.3 ppm. The inhibition of E. elatior against the two enzymes could be an alternative to delay carbohydrate absorption.
Integrating Computational Methods into Antibacterial Drug Discovery and Development from Natural Products Yuliandra, Yori; Syafni, Nova
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 1 (2024): J Sains Farm Klin 11(1), April 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.1.80-85.2024

Abstract

Natural products have long been pivotal in sustaining civilizations due to their medicinal properties and have served as a rich source of bioactive compounds for drug discovery. With the rise of antibiotic-resistant bacteria, there is an urgent need for new antibacterial agents. Natural products, with their diverse chemical structures, provide a promising reservoir for identifying new lead compounds. Historically, the discovery of bioactive natural products often relied on serendipity, but modern advancements in computational approaches, particularly computer-aided drug design (CADD), have revolutionized this process. In the modern era, vast data from advanced technologies can provide valuable insights through computational methods. These approaches enable the structural analysis of molecules and the prediction of their biological activities, accelerating drug discovery. Advances in molecular sciences have identified more antibacterial targets, further facilitating this process. Integrating computational drug design with the study of natural products allows for the efficient identification and optimization of potential antibacterial agents. Moreover, many medicinal plants harbor mechanisms of action that remain unexplored by conventional methods. By employing computational techniques, researchers can uncover these mechanisms and develop novel antibacterial drugs. This combined approach not only enhances our understanding of natural products but also addresses the critical need for new treatments in the fight against bacterial infections.
Enhancing Gambir's Economic Value from Processing to Bath Soap Raw Materials: Community Service Program Uswatul Hasanah; Nova Syafni; Adhitya Jessica; Erizal Zaini; Rini Agustin
Warta Pengabdian Andalas Vol 31 No 2 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.2.277-284.2024

Abstract

Gambir, an extract derived from the leaves and branches of the gambir plant, holds significant potential for enhancing the local economy and its benefits as a cosmetics product. Jorong Balai Tampuak Pinang, Nagari Simpang Kapuak, Kecamatan Mungka, was one of the areas producing traditional gambir in Lima Puluh Kota district, West Sumatra, Indonesia. This community service initiative aimed to augment the economic value of gambir from its processing to raw materials of bath soap. The initiative began with an educational session for training participants, outlining the advantages of gambir in skincare and how to incorporate it into bath soap formulations. Following the learning session, participants actively produced gambir-contained bath soap utilizing the provided formula. The activity received favorable feedback from participants who appreciated enhancing knowledge and skills. The outcomes of this endeavor underscore the substantial potential of developing body care products utilizing gambir as a primary ingredient. Participant testimonials underscore the need to conduct similar community engagement activities to harness Gambir's further utilization of other personal care products. The collaboration between the pharmacy study program and the local community has opened new avenues for local economic development and sustainable growth, significantly impacting the local population's well-being in the region.
Co-Authors . Mansyurdin Adhitya Jessica Adhitya Jessica Amar, Puti Khairunnajwa Amri Bakhtiar Amri Bakhtiar Athallah Fakhriadi DAYAR ARBAIN Deddi Prima Putra Erizal Zaini Faroliu, Goldha Friardi Ismed Hafizatul Akrami Lili Fitriani Lusia Eka Putri Mifta Huljanah Muhammad Idris Nanda Putra Nofrizal Nofrizal Nofrizal Nofrizal Nofrizal Rahmi Yosmar Rahmi Yosmar Rini Agustin Rini Agustin Ryan Fajri Kurniawan Saafrida Saafrida Saafrida Saafrida Suryati Suryati Syafia, Ersa Nur Try Andy Sahputra Try Andy Sahputra Uswatul Hasanah Wiwik Hanifah Yori Yuliandra, Yori