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All Journal Majalah Kedokteran Gigi Indonesia Interdental Jurnal Kedokteran Gigi (IJKG) JURNAL EDUKASI NONFORMAL
Asikin Nur
Bagian Biomedika Kedokteran Gigi, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Public Health Social Sciences

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Dealing with the high-risk potential of COVID-19 cross-infection in dental practice Yulianto, Heribertus Dedy Kusuma; Purwanti, Nunuk; Utami, Trianna Wahyu; Dewi, Anne Handrini; Listyarifah, Dyah; Ruspita, Intan; Nur, Asikin; Susilowati, Heni
Majalah Kedokteran Gigi Indonesia Vol 6, No 1 (2020): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.56588

Abstract

The World Health Organization reported that the SARS-CoV-2 virus has infected more than 5 million people around the world. Dental care providers and health care professionals need to be aware of the high-risk potential of crossinfection since the routes of virus transmission commonly happen through droplets and aerosols. This review aimed at collecting essential knowledge about the COVID-19 needed by dental practitioners. The review focused on the oral involvement in COVID-19, the role of oral transmission as the high-risk potential of cross-infection and recommended strategies to minimize the risk of cross-infection in dental practice. We searched all the published clinical features from PubMed, Google Scholar, Scopus and hand searched library online databases, from January 2015 until May 2020. Keywords used were “COVID-19”, “Dentistry”, “Dental protection”, “Cross-contamination”, “Aerosol and non aerosol”, and ”Povidone-iodine” with their combinations. We identified 52 articles to review after the initial selection with inclusion and exclusion criteria. Results showed use of topical applications of povidine-iodine and viricidal mouthwash could significantly reduce the high-risk of cross-infection from dentistry patients who are asymptomatic with COVID-19 infection. Further safeguards include suspending all non-emergency procedures temporarily and closely screening patients for symptoms which may be suspected to be COVID-19 infection.
Efek antibakteri dan penghambatan biofilm ekstrak sereh (Cymbopogon nardus L.) terhadap bakteri Streptococcus mutans Zwista Yulia Dewi; Asikin Nur; Triana Hertriani
Majalah Kedokteran Gigi Indonesia Vol 1, No 2 (2015): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.292 KB) | DOI: 10.22146/majkedgiind.9120

Abstract

Antibacterial effect and biofilm inhibition Of Lemongrass extract (Cymbopogon nardus L.) against the growth of Streptococcus mutans. Caries prevention can be carried out by several methods. One of them is by controlling the plaque accumulation on the surface of the teeth. Lemongrass (Cymbopogon nardus L) is containing certain compound that can inhibit the growth of bacteria and biofilm. The objective of this research is to observe the influence of antibacterial and biofilm inhibition of lemongrass extract against the growth of S. mutans. Subjects were S. mutans bacteria on KHM90 test as much as 6x108 CFU/ml and on biofilm inhibition test as much as 15x108 CFU/ml. Lemongrass was extracted using petroleum ether followed by using 70% ethanol. Antibacterial activity test carried out with KHM90 determination test using microdilution method on microplate flat bottom 96 wells. Bacteria were prepared by making a suspension in NB media and adjusted to McFarland II standard (6x108 CFU/ml). Biofilm inhibition activity test was performed using microdilution method of the biofilm formed on microplate flat flexible PVC U-bottom 96 wells which were stained using 1% of crystal violet. Bacteria were prepared by making a suspension in BHI media and adjusted to McFarland V standard (15 x108 CFU/ml). The result in the form of optical density (OD) was read by Bio-rad microplate reader Benchmark at a wavelength of 595 nm. The value of IC50 was determined by probit method using SPSS version 15.The results of this study of measurements on KHM90 test showed that 108,36% w/v is capable of inhibiting the growth of bacteria. Biofilm inhibitory activity showed IC50 lemongrass value was 0,137% w/v. The conclusion of this study is that lemongrass extract has antibacterial effect against bacteria S. mutans showed by KHM90 obtained at concentrations of 0,18% w/v and there is lemongrass extract biofilm inhibitory effect against the bacteria S. mutans indicated by IC50 value 0,137%
Dealing with the high-risk potential of COVID-19 cross-infection in dental practice Heribertus Dedy Kusuma Yulianto; Nunuk Purwanti; Trianna Wahyu Utami; Anne Handrini Dewi; Dyah Listyarifah; Intan Ruspita; Asikin Nur; Heni Susilowati
Majalah Kedokteran Gigi Indonesia Vol 6, No 1 (2020): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.56588

Abstract

The World Health Organization reported that the SARS-CoV-2 virus has infected more than 5 million people around the world. Dental care providers and health care professionals need to be aware of the high-risk potential of crossinfection since the routes of virus transmission commonly happen through droplets and aerosols. This review aimed at collecting essential knowledge about the COVID-19 needed by dental practitioners. The review focused on the oral involvement in COVID-19, the role of oral transmission as the high-risk potential of cross-infection and recommended strategies to minimize the risk of cross-infection in dental practice. We searched all the published clinical features from PubMed, Google Scholar, Scopus and hand searched library online databases, from January 2015 until May 2020. Keywords used were “COVID-19”, “Dentistry”, “Dental protection”, “Cross-contamination”, “Aerosol and non aerosol”, and ”Povidone-iodine” with their combinations. We identified 52 articles to review after the initial selection with inclusion and exclusion criteria. Results showed use of topical applications of povidine-iodine and viricidal mouthwash could significantly reduce the high-risk of cross-infection from dentistry patients who are asymptomatic with COVID-19 infection. Further safeguards include suspending all non-emergency procedures temporarily and closely screening patients for symptoms which may be suspected to be COVID-19 infection.
Analisis Perwatakan Tokoh Utama pada Novel Hujan Karya Tere Liye: Kajian Psikologi Sastra Nur Asikin; Septi Gumiandri
JURNAL EDUKASI NONFORMAL Vol 4 No 1 (2023): Jurnal Edukasi Nonformal
Publisher : Universitas Muhammadiyah Enrekang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to describe and identify the character of the main character in the novel entitled "Rain" by Tere Liye. The method used in this study is a qualitative descriptive method. The data source in this study is a novel entitled “Rain” by Tere Liye. The data in this study are fragments of the story in the novel entitled "Rain" by Tere Liye. Data collection is done by observing and documenting methods. Where in the see method uses an advanced technique in the form of a note-taking technique. Documentation is done by taking fragments of the story in the novel and then collecting it in the form of data. Furthermore, the presentation of data analysis was carried out using descriptive methods or informal methods, namely presenting in ordinary words. The results of the study found several characteristics of the main characters in accordance with Freud's theory, namely as follows; in (1.) the id has a reckless, stubborn, disappointed character. (2.) The ego has no self-character, never gives up. (3.) The Super Ego has an honest, caring, patient, jealous character.
The concentration effect of kulim leaf (scorodocarpus borneensis) extract on Streptococcus mutans ATCC 25175 bacterial hydrophobicity and adhesion Utami, Trianna Wahyu; Hapsari, Adhaninggar Ratna; Hanalda, Dhe Rifdania; Nur, Asikin; Yulianto, Heribertus Dedy Kusuma; Purwanti, Nunuk
Majalah Kedokteran Gigi Indonesia Vol 8, No 3 (2022): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.80636

Abstract

With the ability to reduce hydrophobicity and inhibit the adhesion of S. mutans ATCC 25175 bacteria, Kulim leaf extract can be used as an alternative to chlorhexidine mouthwash in caries prevention. The objectives of this study are to determine the effect of Kulim leaf extract on hydrophobicity and adherence of the cariogenic bacteria S. mutans ATCC 25175. The test groups were divided into negative control (DMSO 2%), the treatment group (Kulim leaf extractconcentrations of 1.25%, 2.5%, 5%), and positive control (0.1% chlorhexidine). All of groups were received three replicated tests for hydrophobicity and adherence inhibition of S. mutans ATCC 25175 bacteria. The hydrophobicity test was conducted by providing 3 ml of bacterial suspension of S. mutans ATCC 25175 which had been adjusted to the McFarland 0.5 standard for each group. Furthermore, each test group was vortexed for one minute and left to stand for 15 minutes. Each treatment was tested with a wavelength spectrophotometer of 550 nm before and after the provision of 200 µl of n-hexadecane. The absorbance value on the spectrophotometer was then included in the hydrophobicity formula to determine the hydrophobicity percentage of S. mutans ATCC 25175 against n-hexadecane. To test the bacterial adhesion, the 96 wells microplate was inserted with the kulim leaf extract of each concentration,BHI-B, bacteria according to the McFarland 0.5 standard, and for the positive control and negative control. Afterwards, they were incubated at 37 °C for 24 hours before they were rinsed with distilled water, and stained with 0.1% crystal violet. Then, an optical density reading was performed using a microplate reader with a wavelength of 540 nm. The absorbance value was then included in the formula for percentage of bacterial adhesion inhibition. Post-Hoc LSD testshowed a significant difference in mean difference between the negative control group and the other treatment groups (p<0.05). In addition, it was revealed that there was no significant mean difference between treatment groups, and there was no significant difference between positive control and treatment groups of 2.5% and 5% in the hydrophobicity test. However, there was a significant difference between the positive control and the treatment group of 1.25% in the hydrophobicity test and the treatment group of 1.25%, 2.5%, and 5% in the adherence test. This study concluded that Kulim leaf extract concentration affected hydrophobicity and attachment of S. mutans ATCC 25175 with an effective concentration of 2.5%.
Comparison Effect of Leaves and Bark Extract of Eucalyptus (Melaleuca leucadendra), Sappan (Caesalpinia sappan), and Cinnamon (Cinnamomum zeylanicum) to Reduce Streptococcus mutans Biofilm Formation Utami, Trianna Wahyu; Ekananda, Bernadetha Nathania; Anjani, Yasmin Regita; Listyarifah, Dyah; Nur, Asikin; Syahbudin, Atus
Majalah Kedokteran Gigi Indonesia Vol 9, No 1 (2023): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.83283

Abstract

To evaluate the effect of eucalyptus, sappan, and cinnamon leaf and bark extract on the percentage of S. mutans biofilm formation. The test group was divided into a negative control (1% Dimethyl sulfoxide), a treatment group (eucalyptus, sappan, and cinnamon leaves and bark at concentrations of 50%, 25%, and 12.5%, respectively), and a positive control (0.2% chlorhexidine). Each concentration of eucalyptus, sappan, and cinnamon leaves and barks extract, Brain Heart Infusion Broth (BHI-B), bacteria according to the McFarland 0.5 standard, a positive control, and a negative control were added to a 96-well microplate. They were incubated at 37 °C for twenty-four hours before being rinsed with phosphate buffer saline (PBS) and stained with 0.1% crystal violet. The optical density was then measured using a microplate reader with a 540 nm wavelength. The absorbance value is then factored into the percentage of bacterial adhesion inhibition formula. A statistical test revealed a significant difference (p < 0.05) in the percentage of inhibition between the three extracts of leaves and bark and the negative control group (1% DMSO). There is a significant difference between all leaves and barks concentration and the positive control group except the 50% concentration of sappan leaf group and 50% concentration of cinnamon leaf group. The sappan leaf and cinnamon leaf at 50% concentration exhibit no significant difference (p > 0.05) with the positive control. Eucalyptus, sappan, cinnamon leaves and barks at a concentration of 50% demonstrated effectiveness of the extractant in inhibiting the formation of biofilm masses by S. mutans in comparison with the other group.
Effect Of 8% Ethyl Acetate Fractionated Coriander Seed (Coriandrum sativum) Extract Gel on The Number of Neutrophils and Fibroblasts in The Healing Process of Gingivitis (in vivo Study on Wistar Rats) Sanjaya, Devita; Nur, Asikin; Kuswandari, Sri
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.9724

Abstract

Introduction: Gingivitis is inflammation of the gingiva and the initial stage of periodontal disease, which, if not treated, will become periodontitis. Coriander seeds (Coriandrum sativum) have anti-bacterial and anti-inflammatory properties. This study aimed to determine the effect of 8% ethyl acetate fractionated coriander seed extract gel on the number of neutrophils and fibroblasts in the healing process of gingivitis (in vivo) in Wistar rats. Material and Method: Thirty-six rats were divided into 3 groups: the 8% ethyl acetate fractionated coriander seed extract gel group, the chlorhexidine gel group, and the placebo gel group. Gingivitis was induced by tying a silk ligation to the subgingival area of ​​the lower incisor for 7 days. 0.05 ml of gel was applied twice a day in the gingivitis area. On days 1, 3, 5, and 7, three rats from each group were decapitated, histological preparations were made with HE staining, and the number of neutrophils and fibroblasts was counted using an Optilab microscope with 400x magnification. Healing assessment was measured based on the decrease in the number of neutrophils or the increase in the number of fibroblasts compared to the number of neutrophils or fibroblasts on the initial observation day. Results and Discussions: A significant difference in neutrophil counts was found in the 8% ethyl acetate fractionated coriander seed extract gel group (45.43%) and the placebo gel group (51.67%) on days 3. A significant difference was also found in the number of fibroblast in the 8% ethyl acetate fractionated coriander seed extract gel group (5410%) and the placebo gel group (4470%) on days 5, and between the 8% ethyl acetate fractionated coriander seed extract gel group (8463.33%) and the placebo gel group (7953.33%) on days 7. Conclusion: This research concludes that 8% ethyl acetate fractionated coriander seed extract gel can reduce the number of neutrophils and increase the number of fibroblasts in the gingivitis healing process.
Co-Authors Anjani, Yasmin Regita Anne Handrini Dewi Atus Syahbudin Dyah Listyarifah Ekananda, Bernadetha Nathania Hanalda, Dhe Rifdania Hapsari, Adhaninggar Ratna Heni Susilowati Heni Susilowati Heribertus Dedy Kusuma Yulianto Intan Ruspita Intan Ruspita, Intan Nunuk Purwanti Sanjaya, Devita Septi Gumiandri Sri Kuswandari, Sri Triana Hertriani Trianna Wahyu Utami Zwista Yulia Dewi