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AKTIVITAS ANTIBAKTERI EKSTRAK DAUN RAMBAI (Sonneratia Caseolaris) KONSENTRASI 70%, 80% DAN 90% TERHADAP Streptococcus Mutans IN VITRO Helda Helda; Didit Aspriyanto; R. Harry Dharmawan S
Dentin Vol 4, No 3 (2020)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground:. One of the factors causing dental caries is a microorganism, namely Streptococcus mutans. Rambai leaf extract (Sonneratia caseolaris) contain triterpenoids, flavonoids, tannins, steroids and phenols which have antibacterial activity against the growth of Streptococcus mutans which has the potential to prevent dental caries. Purpose: This study aims to prove the presence of 70%, 80% and 90% antibacterial activity of rambai leaf extract (Sonneratia caseolaris) in inhibiting the growth of Streptococcus mutans in vitro. Methods: This study was a laboratory experimental study, with a post test only design, using a completely randomized design consisting of 5 treatment groups, namely: rambai leaf extract 70%, 80% and 90% (Sonneratia caseolaris), positive control. (Povidone iodine 1%) and negative control (distilled water) were repeated 5 times. Antibacterial activity was assessed from the clear inhibition zone formed on Muller Hinton media by diffusion method. Results: The Kruskal-wallis test showed that the clear inhibition zone formed had a significant difference. The average clear zone of rambai leaf extract (Sonneratia caseolaris) was 70% at 11.6 mm, 80% for 12.9 mm and 90% for 14.2 mm. Conclusion: Rambai leaf extract (Sonneratia caseolaris 70%, 80% and 90% have antibacterial activity in inhibiting the growth of Streptococcus mutans in vitro. Keywords: Antibacterial Activities, Rambai Leaf Extract, Streptococcus mutans. ABSTRAK Latar Belakang: Faktor penyebab terjadinya karies gigi salah satunya adalah mikroorganisme yaitu Streptococcus mutans. Ekstrak daun rambai (Sonneratia caseolaris) mengandung triterpenoid, flavonoid, tanin, streoid dan fenol yang  memiliki aktivitas antibakteri terhadap pertumbuhan Streptococcus mutans yang berpotensi sebagai pencegah karies gigi. Tujuan: Tujuan penelitian ini adalah untuk membuktikan adanya aktivitas antibakteri ekstrak daun rambai (Sonneratia caseolaris) 70%, 80% dan 90% dalam menghambat pertumbuhan Streptococcus mutans in vitro. Metode: Penelitian ini merupakan penelitian eksperimental laboratorik murni (true experimental), dengan post-test only design, menggunakan rancangan acak lengkap terdiri dari 5 kelompok perlakuan, antara lain: ekstrak daun rambai (Sonneratia caseolaris) 70%, 80% dan 90%, kontrol positif (Povidone iodine 1%) dan kontrol negatif (akuades) dilakukan pengulangan sebanyak 5 kali. Aktivitas antibakteri dinilai dari zona hambat bening yang terbentuk pada media Muller Hinton dengan metode difusi. Hasil: Uji Kruskal-wallis menunjukkan bahwa zona hambat bening yang terbentuk memiliki perbedaan yang bermakna. Rata-rata zona bening ekstrak daun rambai (Sonneratia caseolaris) yaitu 70% sebesar 11,6 mm, 80% sebesar 12,9 mm dan 90% sebesar 14,2 mm. Kesimpulan: Ekstrak daun rambai (Sonneratia caseolaris) 70%, 80% dan 90% memiliki aktivitas antibakteri dalam menghambat pertumbuhan Streptococcus mutans in vitro. Kata kunci: Aktivitas Antibakteri, Ekstrak Daun Rambai, Streptococcus mutans.
THE EFFECTS OF SECTION CAESAREA TO EARLY BREASTFEEDING INITIATION: A SYSTEMATIC REVIEW Nur Annisa Fauziyah; Helda Helda
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: The early breastfeeding initiation is one of the crusial process for successful in exclusive breastfeeding, unfortunately based on UNICEF, globally only 45% of newborns were put to the breast within the first hours of life. The other condition, nowdays caesarean sections have become increasingly common in both developed and developing countries, research showed that mothers who delivered their baby section caesarea have a higher percentage failure of early breastfeeding initiation than mother with vaginal delivery, from that condition his research aims to analyze effects section caesarea to early breastfeeding initiation. Methods: This study used systematic review based on the Prisma (Preferred Reporting Items For Systematic Reviews & Meta-Analyses) Protocol to identify all the published literature using relevant keywords. The initial screening was conducted by human population, the year of publication (5 years) and free full text, then reading the titles, abstracts than assessed for eligibility founded 6 articles, those studies included in this review after selected using inclusion and exclusion criteria. Inclusion are journal from rearch reported in english, has no accompanying disease or health problem as cardiac disease, cancer, herpes, HIV/AIDS, obesity ect. The baby is normal, baby can drink orally. Exclusion: the articles published less than 2013, after sectio caesarea mother and infant require special therapy. Results: The studies showed there were effects of section caesarea to early breastfeeding initiation, the mothers who birth their babies with caesarea most of them failure to initiate early breastfeeding. Conclusions: The way to Improve the rates of early breastfeeding initiation with giving antenatal breastfeeding education to all mothers especially who known to be having a cesarean section and health care professionals must support. All of the hospitals must apply baby friendly hospital initiative to support success of early breastfeeding initiation 
Kajian Yuridis terhadap Upaya Preventif Memerangi Tindak Pidana Korupsi dalam Perspektif Hukum Administrasi Negara Eki Rolando; Della Putri Ramadhani; Helda Helda; Putri Safira Apriadi; Rahma Fitri
Mandub : Jurnal Politik, Sosial, Hukum dan Humaniora Vol. 2 No. 4 (2024): Desember : Jurnal Politik, Sosial, Hukum dan Humaniora
Publisher : STAI YPIQ BAUBAU, SULAWESI TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59059/mandub.v2i4.1545

Abstract

In accordance with the mandate of the rule of law, Indonesia has always sought to remain guided by the law as an instrument to realise the original ideals of the nation. We know that Administrative Law is a branch of law that serves to regulate the correlation between the state (in this case, the government) and its citizens. The role of Administration Law becomes one of the pillar guidelines used to always ensure consistency between government action and law in order to be able to perform its functions optimally. However, one of the obstacles that remains the focus of the issue of government organisation is the punishment of corruption by government officials. For that, the primary purpose of this writing is to know further how the efforts to prevent criminal proceedings of corruption in the perspective of the Administrative Law. This article uses normative juridical research methods with qualitative analysis or library study. The material is obtained from reference sources of reading literature that still have relevance to the object of this research. The findings will be analysed and organised systematically in writing in the form of reading descriptions.
Determinants of Antiretroviral Therapy Success in HIV/AIDS Patients Intan Ully Athalia Sihombing; Mondastri Korib Sudaryo; Irva Zulviya Hasyim; Helda Helda; Helwiah Umniyati
Jurnal Ilmiah Kesehatan Masyarakat : Media Komunikasi Komunitas Kesehatan Masyarakat Vol 17 No 2 (2025): JIKM Vol. 17, Issue 2, May 2025
Publisher : Public Health Undergraduate Program, Faculty of Health Science, Universitas Pembangunan Nasional Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52022/jikm.v17i2.805

Abstract

Background: HIV/AIDS is still an important public health issue globally and Antiretroviral therapy (ART), considered as a foundation for the disease care. Succeeding in viral load suppression is very important for successful ART treatment although other factors get involved in this. Objectives The present study is to determine the factors of negative outcome for ART (non- success) based on patient viral suppression in HIV/AIDS, Bekasi district Indonesia. Method: Secondary data from HIV/AIDS Information System (SIHA) at Bekasi District Health Office were extracted with cross-sectional study that involved from January 2023 to September 2024. Patients on ART (n=811). We analyzed data with STATA version 17, performed univariable and bivariable analyses to identify factors associated with viral load suppression Results: Viral load suppression (≤50 copies/ml) was achieved by most patients (87.3%). High adherence (PR Adjusted: 5.27; p=0.000), clinical severity stage (PRA:2.52; p=0.000) and use of TLD regimen (PR Adjusted: ); p= 0.001) were significant predictors of unsuppressed viral load. Suppression rates were better in patients with HIV-negative or unreported status partners (PR Adjusted: 0.78; p=0.004). Conclusion: ART success in Bekasi District is dependent on appointment adherence, clinical stage, ARV regimens and partner is on HIV post- treatment, particularly relevant for national and global HIV/AIDS control strategies in terms of increasing the adherence at same time early initiation of ART as well individualized ARV regimens.