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All Journal BALI MEDICAL JOURNAL (BMJ) E-Jurnal Medika Udayana E-Jurnal Udayana Medica Indonesian Journal of Urology Syntax Literate: Jurnal Ilmiah Indonesia JBN (Jurnal Bedah Nasional) ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico Journal of Anesthesiology and Clinical Research Journal of Global Pharma Technology Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute E-Amal: Jurnal Pengabdian Kepada Masyarakat Folia Medica Indonesiana
Gede Wirya Kusuma Duarsa
Bagian Bedah Urologi Fakultas Kedokteran Universitas Udayana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Journal of Global Pharma Technology

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Perioperative outcome between open renal stone-removal surgery and PCNL in patients with staghorn stones Gede Wirya Kusuma Duarsa
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

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Background: Percutaneous nephrolithotomy (PCNL) has become the treatment of choice for staghorn stones, replacing open stone surgery. However, in a developing country, open stone surgery is still the treatment of choice due to its nature for not requiring endourology devices, it can be performed by a general surgeon, and it is financially acceptable.Objective: This study aims to compare the cost-related outcome between PCNL and open renal stone surgery in patients with staghorn stones.Method: Data were collected retrospectively, taken from patients’ medical records who underwent PCNL and open stone surgery in three hospitals from 2016-2017. Seventy-eight patients were divided equally into PCNL group and open surgery group. Data of the hospital length of stay, the volume of blood loss during surgery, stone-free rate, and post-operative additional procedures were recorded.Outcome Measurements and Statistical Analysis: The data were analyzed using SPSS version 23.0 for Windows.Results: The hospital length of stay was shorter in PCNL compared to open stone surgery (3 vs. 4 days, p<0.001). The post-operative stone-free rate was lower in PCNL compared to open stone surgery (48.7 vs. 92.3%, p<0.001). More post-operative additional procedures were found in PCNL compared to open stone surgery (p<0.001). There was no significant difference in the amount of blood loss during surgery in both groups (p=0.102).Conclusions: PCNL is a minimally invasive procedure that is effective and safe for treating staghorn stones. Nevertheless, in places where PCNL is unavailable, open stone surgery can still be a choice for treatment. 
Correlation among Transforming Growth Factor , Tumour Necrosis Factor- , Prostate Specific Antigen, and Testosterone with Prostate Stromal to Epithelial Ratio in Benign Prostate Hyperplasia Gede Wirya Kusuma Duarsa
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
Publisher : Journal of Global Pharma Technology

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Introduction: Benign Prostatic Hyperplasia (BPH) occurs due to an imbalance between cell proliferation and the apoptotic process. Many factors influence the growth of the prostate. This study aims to determine which factors among TGF-b, TNF-a,, PSA, testosterone, correlate the most the stromal-to-epithelial ratio of the prostate. Methods: The study was conducted in 83 BPH subjects in several hospitals in Denpasar. From all subjects, blood was taken for PSA and testosterone examination. TGF-b and TNF-a were examined from the histopathological examination of prostate tissue specimens. Data were collected, then statistical analysis was done with SPSS 22.0. Results: From all parameters, only PSA was significantly negatively related to stromal-to-epithelial ratio, although the strength was negatively weak (r -0.28). Multivariate analysis showed that the combination of PSA and TGF- levels had an effect of 10.8% on the epithelial-stromal ratio. Conclusion: PSA showed a significant association with the ratio of prostate epithelial stroma and had an effect value of 10.8% when combined with TGF-bKeywords: Prostate enlargement, Epithelial-stromal ratio, TNF-α, TGF-β, PSA, Testosterone.
Co-Authors Anak Agung Gde Oka Aria Kekalih Bramastha A Rosadi, Bramastha A Cita Rosita Sigit Prakoeswa Citra Gading Dea Emmanuel Djodi Sidartha Donny Oktavius Gde Oka, A A Gede Andi Aditya Gede Wirata Gede Wirya Diptanala Putra Duarsa Gede Wirya Diptanala Putra Duarsa Gede Wirya Diptanala Putra Duarsa Gede Wirya Diptanala Putra Duarsa Gusti Ayu Putu Nilawati Heri Wibowo I Gde Raka Widiana I Gusti Ayu Irma Vitriani I Gusti Ayu Putri Purwanthi I Gusti Bagus Dharma Prakasa Musti I Ketut Widiana I Made Nugraha Gunamanta Sabudi I Nengah Wiadi I Nyoman Semadi I Wayan Niryana I Wayan Yudiana I.G. Darma-Kusuma Ida Bagus Putra Manuaba Ida Bagus Putra Pramana Irfan Wahyudi Kadek Budi Santosa Ketut Putu Yasa Krishna, I Komang O. Lisnawati Rachmadi Marleen Nurhaen - Nyoman Golden Nyoman Khrisna Dharmawan Oka Udrayana Oka, AA Gde Oka, Anak A.G. Paksi Satyagraha Pande Made Wisnu Tirtayasa Pande Putu Yuli Anandasari Paulina Magdalena Ponco Birowo Pontisomaya Parami Pradiptha, I Nyoman Tri Pramana, Putu Bagus Gin Gin Prayudi, I Nyoman Gede Putra, Bismantara Aditya Putu Astri Novianti Putu Kurnia Darma Pratama Putu Primeriana Nugiaswari Raharja, Putu Angga Risky Rika Lesmana, Rika S. F. Laura, S. F. Sri Maliawan Sugianto, Ronald Suryawisesa, Ida Bagus Made Teguh Dwi Nugroho, Teguh Dwi Tjokorda Gde Agung Senapathi Tjokorda Gde Bagus Mahadewa Udiyana, Nyoman Dwi Maha Wayan Sudana Yenny Kandarini