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The Risk of Infection Human Papilloma Virus Infection in Acceptors of Depot Medroxyprogesterone Acetate Contraceptions Aras, Baharuddin; Tahir, Mardiah; Arifuddin, Sharvianty; Hartono, Eddy; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: Cervical cancer is the second most prevalent cancer inwomen around the world and the most common cancer in womencausing death. This study aims to analyze the connection betweeninfection of human papilloma virus (HPV) 16/18 and cervicalchanges in the acceptors of Depot Medroxyprogesterone Acetate(DMPA) Contraceptions and nonacceptors of Depot MedroxyprogesteroneAcetate (DMPA) Contraceptions.Methods: The research was conducted at the Public ServiceInstitution of Dr. Wahidin Sudirohusodo hospital, and privatemidwife clinics for seven months from December 2015 to June 2016.The research design is cross-sectional with. The samples were fortyacceptors of Depot Medroxyprogesterone Acetate (DMPA) and fortynon-acceptors of Depot Medroxyprogesterone Acetate (DMPA)contraception. Prevalence of HPV 16/18 and cervical cytologychanges were examine using the polymerase chain reaction andliquid base cervical cytology.Results: The results showed there was no significant relationshipbetween long-term use of DMPA contraceptives with HPV 16 and 18.There was no significant relationship between long-term use ofDMPA contraceptives with cervical cytology changes. There was nosignificant relationship between HPV 16 and 18 infections with theoccurrence of cervical cytology changes in long-term use of DMPAcontraceptives.Conclusion: The long-term use of DMPA contraceptive does notincrease the risk of HPV 16 and 18 infections. Also does not causecervical cytology changes that lead to cervical malignancy.Keywords: cervical cytology changes, Depot MedroxyprogesteroneAcetate (DMPA) contraception, HPV 16/18 infection

Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery Nurdin, Azizah; Irianta, Trika; Tahir, Mardiah; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the obstetric risk factors of the analincontinence in mothers with previous history of vaginaldelivery.Methods: The was a case-control study conducted in the Obstetricsand Gynecology Department of Dr.Wahidin Sudirohusodo Hospital,Faculty of Medicine, Universitas Hasanuddin, Makassar, during theperiod of February 2015 through January 2016. The researchinstruments were used to evaluate obstetric risk factors and theanal incontinence was the self-administered questionnaire and FecalIncontinence Severity Index. The data were analyzed statisticallyusing the Chi-square test with the significant value of p<0.05.Results: A total of 300 subjects were recruited in this study. Theresearch results indicated that the parity of  3, the assisted vaginaldelivery history (vacuum extraction), and the prolong secondstage of labor had a significant correlation with the anal incontinencewith p value=0.026, OR (95% CI) = 1.8 (1.07-3.03), p=0.018with OR (95% CI) =3.65 (1.2-10.7) and p=0.006 with OR (95% CI)= 2.9 (1.2-6.7).The history of episiotomy and the delivery of thebaby  4000 gram had no correlation with the anal incontinence.Conclusion: Parity, vacuum delivery and prolong second stage oflabor have an association with anal incontinence among womenwho has history of vaginal delivery.Keywords: anal incontinence, obstetric risk factors, vaginal delivery

Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery Nurdin, Azizah; Irianta, Trika; Tahir, Mardiah; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the obstetric risk factors of the analincontinence in mothers with previous history of vaginaldelivery.Methods: The was a case-control study conducted in the Obstetricsand Gynecology Department of Dr.Wahidin Sudirohusodo Hospital,Faculty of Medicine, Universitas Hasanuddin, Makassar, during theperiod of February 2015 through January 2016. The researchinstruments were used to evaluate obstetric risk factors and theanal incontinence was the self-administered questionnaire and FecalIncontinence Severity Index. The data were analyzed statisticallyusing the Chi-square test with the significant value of p<0.05.Results: A total of 300 subjects were recruited in this study. Theresearch results indicated that the parity of  3, the assisted vaginaldelivery history (vacuum extraction), and the prolong secondstage of labor had a significant correlation with the anal incontinencewith p value=0.026, OR (95% CI) = 1.8 (1.07-3.03), p=0.018with OR (95% CI) =3.65 (1.2-10.7) and p=0.006 with OR (95% CI)= 2.9 (1.2-6.7).The history of episiotomy and the delivery of thebaby  4000 gram had no correlation with the anal incontinence.Conclusion: Parity, vacuum delivery and prolong second stage oflabor have an association with anal incontinence among womenwho has history of vaginal delivery.Keywords: anal incontinence, obstetric risk factors, vaginal delivery

The Risk of Infection Human Papilloma Virus Infection in Acceptors of Depot Medroxyprogesterone Acetate Contraceptions Aras, Baharuddin; Tahir, Mardiah; Arifuddin, Sharvianty; Hartono, Eddy; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: Cervical cancer is the second most prevalent cancer inwomen around the world and the most common cancer in womencausing death. This study aims to analyze the connection betweeninfection of human papilloma virus (HPV) 16/18 and cervicalchanges in the acceptors of Depot Medroxyprogesterone Acetate(DMPA) Contraceptions and nonacceptors of Depot MedroxyprogesteroneAcetate (DMPA) Contraceptions.Methods: The research was conducted at the Public ServiceInstitution of Dr. Wahidin Sudirohusodo hospital, and privatemidwife clinics for seven months from December 2015 to June 2016.The research design is cross-sectional with. The samples were fortyacceptors of Depot Medroxyprogesterone Acetate (DMPA) and fortynon-acceptors of Depot Medroxyprogesterone Acetate (DMPA)contraception. Prevalence of HPV 16/18 and cervical cytologychanges were examine using the polymerase chain reaction andliquid base cervical cytology.Results: The results showed there was no significant relationshipbetween long-term use of DMPA contraceptives with HPV 16 and 18.There was no significant relationship between long-term use ofDMPA contraceptives with cervical cytology changes. There was nosignificant relationship between HPV 16 and 18 infections with theoccurrence of cervical cytology changes in long-term use of DMPAcontraceptives.Conclusion: The long-term use of DMPA contraceptive does notincrease the risk of HPV 16 and 18 infections. Also does not causecervical cytology changes that lead to cervical malignancy.Keywords: cervical cytology changes, Depot MedroxyprogesteroneAcetate (DMPA) contraception, HPV 16/18 infection

Laporan Kasus Transposition of Great Arteries (TGA): Diagnosis Prenatal Chalid, Maisuri T.; Choukrosimon, Jeanette M.
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.592

Pendahuluan: Transposisi arteri besar (TGA) adalah kelainan jantung bawaan pada anak yang terjadi akibat ketidaksesuaian pertukaran sistem arterioventrikular, yang menyebabkan sianosis pada bayi baru lahir. Tulisan ini melaporkan kasus TGA yang didiagnosis melalui ultrasonografi prenatal dan kemudian menjalani prosedur balloon atrial septastomy (BAS) setelah lahir.Kasus: Seorang ibu berusia 33 tahun hamil dengan janin yang dicurigai TGA berdasarkan hasil ekokardiografi janin melalui visualisasi outflow tract paralel dan transposisi arteri pulmonalis di tengah antara aorta dan vena cava superior pada potongan RVOT, yang awalnya didiagnosis pada usia kehamilan 34 minggu. Perencanaan persalinan dan perawatan pascakelahiran dipersiapkan melalui kolaborasi multidisiplin antara divisi fetomaternal, perinatologi, kardiologi anak, dan ahli bedah kardiotoraks. Setelah bayi lahir, segera dilakukan ekokardiografi yang menunjukkan TGA dan defek septum atrium (ASD) kecil, selanjutnya bayi baru lahir segera menjalani prosedur BAS oleh kardiologi pediatrik. Kesimpulan: Diagnosis prenatal ultrasonografi TGA memungkinkan perencanaan persalinan, perawatan perinatologi dan prosedur BSA sebelum tindakan bedah.A case report of Transposition of Great Arteries (TGA): Prenatal DiagnosisAbstract Introduction: Transposition of the Great Arteries (TGA) is a pediatric congenital heart defect that occurs in incompatibility of the arterioventricular exchange system, which results in cyanosis in a newborn baby. We reported a case of TGA that was diagnosed by prenatal ultrasonography and then underwent a balloon atrial septostomy (BAS) procedure after birth.Case Report: A 33-year-old mother pregnant with a fetus suspected of TGA based on the results of prenatal fetal echocardiography through visualization of a parallel outflow tract and transposition of the pulmonary artery in the middle between the aorta and superior vena cava at RVOT level, which initially diagnosed at 34 weeks of gestational age. Birth planning and perinatal care were prepared through multidisciplinary collaboration between the fetomaternal division, perinatology, pediatric cardiology, and cardiothoracic surgeon. After the baby was born, an echocardiography was immediately performed, showing TGA and small ASD, and then the newborn had BAS procedure by pediatric cardiology.Conclusion: A prenatal diagnosis of TGA through ultrasonography provides a better outcome that allows for labor planning, perinatology care, and BAS procedures before surgery.Key word : TGA, ccTGA, ASD, Transposition of Great Arteries.

Hubungan 8 OHdG (8-Hydroxy-2- Deoxyguanosin) Urin Neonatus dan Preeklamsia Tannur, Sebastianus; Lukas, Efendi; Mailoa, Johnsen; Alasiry, Ema; Irianta, Trika; Chalid, Maisuri T.
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.582

Pendahuluan: Preeklamsia merupakan penyakit dengan berbagai teori (disease of theory) yang menggambarkan ketidakpastian patofisiologi dan penyebabnya. preeklamsia bukan hanya menyebabkan komplikasi terhadap maternal namun juga menimbulkan komplikasi terhadap janin, baik jangka pendek maupun jangka panjang. Peningkatan jumlah radikal bebas merupakan tanda terjadinya stres oksidatif pada kehamilan dengan preeklamsia. 8-OHdG adalah produk utama yang dibentuk dari radikal hidroksil pada residu guanine DNA.Metode: Penelitian ini merupakan penelitian analitik yang dikembangkan dengan desain penelitian cross-sectional. Sampel penelitian adalah neonatus yang lahir dari wanita hamil dengan dan tanpa didiagnosa preeklamsia. Pengambilan sampel dilakukan secara purposive sampling. dilakukan di Rumah Sakit Wahidin Sudirohusodo,dan rumah sakit jejaring pendidikan. Pengujian/running sampel dilakukan di unit Laboratorium Penelitian RSPTN Universitas Hasanuddin dengan metode Elisa. Data dianalisis dengan uji Chi squae, uji Mann whitney dan uji Kruskal wallis Hasil: Hasil penelitian yang telah dilakukan terdapat sebanyak 82 orang yang terbagi menjadi 41 orang sampel yang merupakan kelompok dengan preklamsia dan 41 orang sampel kelompok kontrol (normal). Berdasarkan hasil penelitian yang telah dilakukan mengenai kadar 8-OHdG urin neonatus (8-hydroxy-2- deoxyguanosin) pada kehamilan dengan Preeklamsia diperoleh nilai rerata kadar 8-OHdG urin neonatus pada kehamilan normal sebesar 3.79±1.99, sedangkan kehamilan dengan preeklamsia sebesar 14.25±16.81. uji statistik chi-square menunjukkan nilai p sebesar 0.00 dimana nilai p<0.05 yang artinya terdapat perbedaan kadar 8-OHdG urin neonatus terhadap kejadian preeklamsia dan ibu hamil normal pada penelitian ini. Kesimpulan: Terdapat perbedaan yang signifikan bermakna kadar 8-OHdG urin neonatus yaitu lebih tinggi kadar pada ibu hamil penderita preeklamsia daripada ibu hamil normal.Relationship Between 8 OHdG (8-Hydroxy-2- Deoxyguai›osine) in Neonate Urine and PreeclampsiaAbstractIntroduction: Preeclampsia is a disease with various theories (disease of theory) that describes the uncertainty of its pathophysiology and causes. Preeclampsia not only causes complications for the mother but also causes complications for the fetus, both short and long term. An increase in the number of free radicals is a sign of oxidative stress in preeclampsia. 8-OHdG is the main product formed from hydoxyl radicals in DNA guanine residues. Method: The research was an analytical study developed with a cross-sectional research design. The research sample was neonates born to pregnant women with and without a diagnosis of preeclampsia. The sample was determined by using purposive sampling technique carried out at Wahidin Sudirohusodo Hospital and educational network hospitals. Sample testing was carried out at Hasanuddin University RSPTN Research Laboratory unit using Elisa method. Data were analyzed using Chi square test, Mann Whitney test, and Kruskal Wallis test. Results: The research was carried out to 82 people who were divided into 41 samples in the group with preeclampsia and 41 samples in the control group (normal). Based on the results of research that has been carried out regarding the level of 8-OHdG in neonate urine (8-hydroxy-2-deoxyguanosine) in pregnancies with preeclampsia, the mean value of 8-OHdG level in neonate urine in normal pregnancies is 3.79 z 1.99, while the one in pregnancies with preeclampsia it is 14.25 z 16.81. The chi-square statistical test shows a p value 0.00 which p value <0.05, which means that there is a difference in the level of 8-OHdG in neonate urine in the occurrence of preeclampsia and normal pregnant women. Conclusion: There is a significant difference between the level of 8-OHdG in neonate urine, where the level is higher in pregnant women with preeclampsia than in normal pregnant women.Key words: 8-OHdG, neonate urine, preeclampsia

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