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All Journal Jurnal Kebijakan Kesehatan Indonesia Global Medical and Health Communication Jurnal Integrasi Kesehatan dan Sains Jurnal Riset Kedokteran Bandung Conference Series : Medical Science Global Medical and Health Communication
Fajar Awalia Yulianto
Universitas Islam Bandung
Humanities Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Association of Hematocrit and HbA1c as Indicators of Glycemic Control in Diabetes Mellitus Yuke Andriane; Sara Puspita; Ratna Damailia; Fajar Awalia Yulianto
Global Medical & Health Communication (GMHC) Vol. 14 No. 2 (2026): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v14i2.8985

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood sugar levels that can damage various organs, including the heart, blood vessels, kidneys, and nerves. Diagnosing DM typically involves assessing blood glucose levels and hemoglobin A1c (HbA1c), which reflects average glucose levels over the past 2 to 3 months. HbA1c testing has limitations, including interference from red blood cell lifespan, relatively high costs, and limited availability in some laboratories in Indonesia. Hematology parameters are crucial for diagnosis, including hematocrit, which is associated with blood viscosity, inflammation, and hyperinsulinemia. These conditions are closely associated with the clinical state of Diabetes mellitus. This research aims to analyze the association between hematocrit and HbA1c to identify alternative tests for predicting glycemic status. A cross-sectional study was conducted among 603 patients with diagnosed type 2 diabetes who visited the outpatient department at Al Islam Hospital from January 2018 to December 2019, selected through total sampling. Data were analyzed using multiple linear regression to assess the association between hematocrit and HbA1c, adjusting for confounders. A p-value <0.05 was considered statistically significant. The mean hematocrit level is 41.23±6.21, and HbA1c is 7.87±2.49. The results demonstrated a positive association between increased hematocrit and increased HbA1c, although the effect size is small and statistically insignificant after adjusting for age and sex (β=0.03; 95% CI=−0.004, 0.06; p=0.08; adjusted R-squared=0.004), where an increase of 1 unit of hematocrit is associated with a rise of 0.03 units of HbA1c in this study. In conclusion, hematocrit levels cannot yet serve as a substitute for HbA1c for assessing a patient’s glycemic status.
Co-Authors Aida Nur Rahmah Widodo Andriane, Yuke Anggia Skynta Anggia Skynta Febrianty Ariko Rahmat Putra Aulia Nur Amalia Aulia Rahma Bestari Yuniah Bestari Yuniah Budiman Budiman , Budiman Dede Setiapriagung Devy Claudia Dewi Nurfitriani Rohmah Soleh Eka Nurhayati Eva Rianti Indrasari Farras Oktavidya Duwandani Febyana Rosarianto Gaida Salsabila Gaida Salsabila Habib Birham Ali Haris Nugroho Herri S. Sastramihardja Hikmah Azzahro Hikmah Azzahro Hilmi Sulaiman Rathomi Ieva B Akbar Indriani Sekar Arum Intan Purnamasari Munajat Lisa Adhia Garina Lisa Himawati Lisa Nuril Himawati Livia Assyifa Rachman M. Ahmad Djojosugito M. Insan Kamil Mahmudah Mahmudah Meike Rachmawati Meta Maulida Damayanti Mohamad Daffa Putra Utama Noeradiana Muhamad Faishal Ramadhan Muhamad Faishal Ramadhan Muhammad Agie Najibullah Wijaya Muhammad Alief Abdul ‘Aziiz Muhammad Ilham Halim Muhammad Jordan Nazmi Abiyah Novy Latifah Nurul F Nurul Romadhona Paulina Maresta R. Kince Sakinah Raden Anita Indriyanti Raden Ganang Ibnusantosa Ratna Damailia Rifa Nataputri Rizki Perdana Romy Reynaldi Gunawan Rosady, Dony Septriana Sadeli Masria Salman Barlian Sandy Faizal Sandy Faizal Santun Bhekti Rahimah Sara Puspita Silma Nur Awali Wardah Siska Nia Irasanti Sumayya Nuri Fuadana Aulia Ul Haque Susan Fitriyana Titik Respati Tony S. Djajakusumah Tresnasari, Cice Tresya Anggi Tania Tri Yunis Miko Wahyono Utama Noeradiana, Mohamad Daffa Putra Vihannis Rahmanda Wendy Darmawan Widhy Yudistira Nalapraya Winni Maharani Wiwiek Setiowulan Yoyoh Yusroh Yudi Feriandi Yuktiana Kharisma Yuniarti