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Efektivitas Rebusan Daun Tembakau Kasturi (Nicotiana Tabacum) Sebagai Pembersih Gigi Tiruan Resin Poliamida (Nilon Termoplastik) Terhadap Penurunan Jumlah Koloni Candida Albicans FX Ady Soesetijo; Lusi Hidayati; Kintan Rachmawati Puspitarini
Innovative: Journal Of Social Science Research Vol. 3 No. 2 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i2.723

Abstract

Pendahuluan: Resin poliamida memiliki kekurangan permukaannya yang kasar. Kekasaran permukaan akan menyebabkan pemakai gigi tiruan mengalami denture stomatitis. Perlu dilakukan pembersihan secara rutin agar kebersihannya terjaga. Tembakau dapat digunakan sebagai bahan pembersih gigi tiruan karena mengandung senyawa alkaloid nikotin dan flavonoid. Esktrak nikotin berpengaruh dalam penghambatan pertumbuhan pada beberapa jenis mikroba. Flavonoid memiliki sifat fungistatik dan fungisidal. Penelitiannya sebelumnya menyatakan bahwa, rebusan daun tembakau memiliki efektivitas sebagai pembersih gigi tiruan. Tujuan: Menganalisis efektivitas rebusan daun tembakau kasturi (Nicotiana tabacum) sebagai pembersih gigi tiruan resin poliamida (nilon termoplastik) terhadap penurunan jumlah koloni Candida albicans. Metode: Experimental laboratory dengan rancangan penelitian post test only control group design. Sampel resin poliamida berbentuk lempeng ukuran 8 x 8 x 2 mm sebanyak 25 dibagi menjadi 5 kelompok. Sampel dikontaminasi dengan Candida albicans setelah direndam dalam kontrol negatif (akuades) selama 6 jam, kontrol positif sodium hypochlorite (NaOCl) 0,05% selama 6 jam, dan rendaman daun tembakau konsentrasi 10%, 25%, dan 50% selama 6 jam. Sampel diletakkan dalam media sabouraud dextrose broth (SDB). Pengujian efektivitas rebusan daun tembakau dilakukan dengan menentukan nilai absorbansi kekeruhan media SDB menggunakan spektrofotometer. Data dianalisis menggunakan One Way ANOVA dan Least Significant Difference (LSD). Hasil: Rata-rata jumlah koloni C. albicans pada rebusan daun tembakau 10% sebanyak 6,098 x 108 CFU/ml. Rebusan daun tembakau 25% sebanyak 3,525 x 108 CFU/ml. Rebusan daun tembakau 50% sebanyak 1,215 x 108 CFU/ml. Sodium hypochorite 0,05% sebanyak 0,476 x 108 CFU/ml. Aquades steril sebanyak 6,431 x 108 CFU/ml. Simpulan: Rebusan daun tembakau kasturi (Nicotiana tabacum) sebagai bahan pembersih gigi tiruan efektif terhadap penurunan jumlah koloni Candida albicans.
Hubungan Tingkat Pengetahuan Tentang Vaksinasi Terhadap Kesediaan Vaksinasi Booster COVID-19 Pada Radiografer di Wilayah Jember Pangastuti, Fadilah Tyas Widarti; Prasetyarini, Swasthi; Soesetijo, FX Ady
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 21 No 1 (2024)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v21i1.47340

Abstract

Radiographers are at high risk of being infected with COVID-19 related to the most common transmission of COVID-19, so radiographers must be vaccinated. Antibody levels from primary vaccine can only last for 12 to 20 weeks, so booster vaccine is needed. Booster vaccination is one of health behaviors that divided into three domains: cognitive (knowledge), affective (attitudes), and psychomotor (actions). Based on the background above, the authors are interested in researching the relationship between knowledge level about vaccination and willingness to be vaccinated COVID-19 booster among radiographers at Jember. This type of research is a correlational analytic survey with a cross-sectional approach. Population in this research were all radiographers who are members of the Indonesian Radiographers Association (PARI) and active in Jember. The sampling method using total sampling (n=60). Data analysis in this research included editing, scoring, coding, tabulating, univariate analysis, normality test, and bivariate analysis (Rank Spearman Correlation Test) using IBM SPSS Statistics 25 software. Respondent's knowledge level about vaccination showed 46% good, 27% moderate, and 27% less. Respondent’s willingness to be vaccinated COVID-19 booster showed 47% good, 43% moderate, and 10% less. Rank Spearman Correlation Test (Spearman Rho) showed p value or Sig. (2- tailed) of 0.001 and correlation coefficient was 0.43 (+). There is a significant relationship between knowledge level and willingness to be vaccinated COVID-19 booster among radiographers at Jember with moderate correlation strength and unidirectional correlation.
The Potential Of Avocado Seed Extract (Persea Americana) In Inhibiting The Release Of Metal Ions In Cuniti And Stainless Steel Based Orthodont Wire Sandra Devi, Leliana; Prijatmoko, Dwi; Joelijanto, Rudy; Prasetyarini, Swasthi; Herniyati; Soesetijo, FX Ady; Sutjiati, Rina; Sekar Asmarani Subagyo, Aura; Bayu Mustika Aji, Erlangga
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 2 (2024): May 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.322

Abstract

The release of ions is the initial stage of the corrosion process in an orthodontic wire. Continuous release of ions can reduce the effectiveness and performance of the orthodontic wire. Continuous release of ions in CuNiTi orthodontic wire can change the properties of the wire and trigger hypersensitivity reactions, also in stainless steel orthodontic wire which experiences continuous release of ions can reduce its stiffness. The tannin in avocado seeds is useful as a corrosion inhibitor it can inhibit the release of ions because they are able to bind with metal ions and form a passive layer also able to bind with Fe ions in stainless steel orthodontic wires to form a passive surface layer which is able to inhibit the release of ions when the corrosion process occurs. The aim of this research is to determine the effect of avocado seed extract as a corrosion inhibitor on the release of metal ions from CuNiTi and stainless steel orthodontic wires. Rectangular CuNiTi and stainless steel orthodontic wires measuring 0.017 x 0.025 inches were taken in 3 groups (1 control group soaked in artificial saliva and 2 treatment groups soaked in avocado seed extract). The samples were soaked in avocado seed extract with a concentration of 1.5 g/L and 2 g/L for 7 days. To see the release of ions, an X-Ray Fluorescence test is carried out. In CuNiTi orthodontic wire from the one way ANOVA test showed that there was a significant difference between the control group and all treatment groups on Cu, Ni and Ti ions. The Post Hoc LSD test showed that there were significant differences between the control group, treatment group 1 and treatment group 2 in Cu, Ni and Ti ions with a p value. In stainless steel orthodontic wire, the one way ANOVA test showed that there was a significant difference between the control group and all treatment groups in Fe and Ni ions but not significant in Cr ions in the ion release test with a p value <0.05. The Post Hoc LSD test showed that there were significant differences between the control group, treatment group 1 and treatment group 2 in Fe and Ni ions with a p value <0.05. Providing avocado seed extract with tannin content at concentrations of 1.5 g/L and 2 g/L can inhibit the rate of ion release in CuNiTi and stainless steel orthodontic wires due to the corrosion process.
Effect of 25% Tobacco Leaf Extract (Nicotiana Tabacum L.) as a Denture Cleaning Paste on Surface Roughness and Color Change Thermoplastic Nylon Parnaadji, Rahardyan; Naini, Amiyatun; Soesetijo, FX Ady; Kristiana, Dewi
Jurnal Riset Kesehatan Vol 13 No 1 (2024): MEI 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i1.10677

Abstract

Thermoplastic nylon as a denture base requires mechanical cleaning with denture paste. Previous research showed that tobacco leaf extract paste (TLEP) 25% was fungistatic on thermoplastic nylon denture bases. The aim is to evaluate the roughness and colour changes of thermoplastic nylon against tobacco leaf extract paste 25% during one year of simulated use. This research hypothesizes that thermoplastic nylon's roughness and colour value will decrease further after brushing using 25% TLEP. Sample groups include brushing without paste, paste without TLEP 25% and TLEP 25%. The sample size for each group was 15 samples; measurements use a surface roughness tester and a colour reader. Brushing was carried out for 23.5 minutes on a plate measuring 60x10x2.5 mm as a surface roughness test and 3.90 minutes on a plate measuring 10x10x2.5 mm as a colour change test. The sample size for each group was 15 samples; measurements use a surface roughness tester and a colour reader. The research results were tested using Kolmogorov-Smirnov and Levene and One-way ANOVA with a significance level of 0.05. There were no differences in surface roughness and colour changes on thermoplastic nylon plates after brushing with 25% TLEP (p>0.05). This study concluded that 25% TLEP did not affect increasing surface roughness and changing the colour of thermoplastic nylon plates with values below the threshold.
Pengaruh Pasta Ekstrak Daun Tembakau terhadap Kekuatan Transversa Gigi Tiruan Resin Akrilik Heat Cured Lestari, Diah Ayu; Soesetijo, FX Ady; Parnaadji, Rahardyan
Denta Journal Kedokteran Gigi Vol 20 No 1 (2026): February
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v20i1.8

Abstract

Background: Removable dentures are prosthetic devices used to replace missing teeth. Acrylic resin is the most commonly used material for denture base fabrication. Plaque accumulation on improperly cleaned denture bases can lead to denture-associated stomatitis. Tobacco leaves have potential as a denture cleaning paste due to their antibacterial and antifungal properties. However, their phenol content may degrade polymer bonds and reduce the transverse strength of heat-cured acrylic resins. Objective: This study aims to investigate the effect of using 25% and 50% tobacco leaf (Nicotiana tabacum L.) extract paste as a denture cleaning agent on the transverse strength of heat-cured acrylic resin. Method: This study used an experimental laboratory design with a post-test-only control group. Thirty rectangular block-shaped samples (60x12x3 mm) were divided into one control group (K) and two treatment groups (n=10), which were brushed with 25% (T1) and 50% tobacco leaf extract paste (T2), respectively, for 28.2 minutes. Transverse strength was tested using a universal testing machine with the three-point bending test method. Results: The transverse strengths of groups K (126.926 MPa), T1 (103.136 MPa), and T2 (83.001 MPa) were determined. The parametric test results indicated significant differences between groups K and T2 (p=0.001) and between T1 and T2 (p<0.001). However, no significant difference was observed between groups K and T1 (p=0.052). Conclusion: This study found a decrease in the transverse strength of heat-cured acrylic resin after brushing with tobacco leaf extract paste. 
Role of cassava starch (Manihot esculenta Crantz) in reducing candida albicans adhesion on soft denture liners: an experimental study Adena, Afif Surya; Naini, Amiyatun; Soesetijo, FX Ady; Kristiana, Dewi; Parnaadji, Rahardyan; Hardita, Ardhianing
Padjadjaran Journal of Dentistry Vol 38, No 1 (2026): March 2026
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol38no1.68181

Abstract

Introduction: Soft denture liners can be an alternative solution for various removable denture problems, but they still have several limitations, such as promoting Candida albicans adhesion to dentures. Modifications incorporate cassava starch. The aim of this result is toanalyze the role of cassava starch in reducing Candida albicans adhesion on soft denture liners. Methods: This laboratory experimental study used twenty-seven disc-shaped heat-cured acrylic plates with a diameter of 10 mm and a thickness of 2 mm divided into three groups: acrylic plate without a coating (negative control group), acrylic plate coated with soft denture liners (positive control group), and acrylic plate coated with a soft denture liner containing cassava starch 15% (treatment group). The samples were soaked in artificial saliva for 1 hour, then contaminated with Candida albicans by placing them in a test tube containing a Candida albicans suspension, and incubated for 24 hours at 37°C. Samples were rinsed twice with PBS, then placed in a test tube containing 10 mL of Sabouraud's broth and vortexed for 30 seconds. The turbidity of the released Candida albicans was measured using a spectrophotometer. Absorbance data were analyzed using one-way ANOVA and post hoc LSD. Results: Turbidity testing using a spectrophotometer at 600 nm showed the average absorbance values were 0.013 for negative control group, 0.028 for the positive control group, and 0.019 treatment group. The results of the one-way ANOVA test showed a p-value of 0.004 (<0.05), indicating a significant difference between the groups. Further post hoc LSD tests showed that the positive control group had the highest absorbance value. At the same time, there was no significant difference between the negative control group and treatment group. Conclusion: Cassava starch inhibits Candida albicans adhesion to the soft denture liners.