Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Biotropika Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Sadewa: Jurnal Pengabdian Masyarakat
Khoirun Nisyak
Array
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Aktivitas Antibakteri Nanoemulsi Minyak Lengkuas (Alpinia galanga L. Willd) dalam menghambat pertumbuhan Helicobacter pylori Yulianto Ade Prasetya; Khoirun Nisyak; Eviomitta Rizki Amanda
Biotropika: Journal of Tropical Biology Vol 7, No 3 (2019)
Publisher : University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.biotropika.2019.007.03.7

Abstract

Helicobacter pylori termasuk patogen opportunistik yang memiliki ciri berupa Gram negatif, flagela lopotrikus, tidak berkapsul, dan urease positif. Bakteri ini mampu menyebabkan gastritis, tukak lambung, dan kanker lambung. Penelitian ini bertujuan untuk mengetahui aktivitas nanoemulsi minyak lengkuas (Alpinia galanga L. Willd) dalam menghambat pertumbuhan bakteri Helicobacter pylori. Nanoemulsi minyak lengkuas dibuat dengan bantuan magnetic stirer dan ultrasonikator kemudian dianalisa ukurannya dengan Particle Size Analyzer. Uji aktivitas terhadap H. pylori dilakukan dengan metode difusi sumuran. Hasil penelitian menunjukkan bahwa nanoemulsi minyak lengkuas 1% (ukuran droplet 19.9 nm) mampu menghambat bakteri H.pylori dengan zona hambat sebesar 9,5 mm. Nanoemulsi minyak lengkuas dapat digunakan sebagai kandidat pengobatan infeksi lambung sehingga mampu mencegah karsinoma lambung.
PEMBERDAYAAN MASYARAKAT MELALUI PROGRAM STOP STUNTING DI KABUPATEN SIDOARJO Arif Rahman Nurdianto; Farida Anwari; Acivrida Mega Charisma; Martina Kurnia Rohmah; Khoirun Nisyak
Jurnal SADEWA Vol 2 No 01 (2024): Sadewa: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/js.v2i1.672

Abstract

The problem of stunting is still a health problem that is a major concern for the Sidoarjo Regency government. While the stunting rate at the national level and East Java will decrease in 2022, Sidoarjo Regency shows an increase. In efforts to prevent and overcome stunting, the Sidoarjo Regency government has focused efforts in several villages spread across a number of sub-districts. Furthermore, the aim of this community service activity is to provide education about stunting and its prevention. This community empowerment activity consists of outreach activities to high school students as stunting ambassadors, and training on nutritious food processing attended by PKK cadres in Sidoarjo which is packaged in the Stop Stunting program. The activity method is carried out through coordination with the government, entrepreneurs and educational institutions, counseling of PKK cadres and high school student representatives, as well as training in processing nutritious food ingredients. This activity was attended by 50 students and counseling guidance teachers, as well as 100 PKK cadre mothers in the Sidoarjo area. Overall, the activities in the Stop Stunting program can be implemented well thanks to the cooperation of all related parties. The community service activities that have been carried out are able to increase participants' knowledge about stunting as well as efforts to prevent it, including increasing the ability of PKK cadres to process food ingredients..
Potensi Jintan Hitam (Nigella sativa) sebagai Agen Antibakteri terhadap Bakteri Patogen Klinis Allyssia Salma; Kadeq Novita Prajawanti; Bella Fevi Aristia; Khoirun Nisyak; Widji Soeratri
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.757

Abstract

Antibacterial substances such as thymoquinone, carvacrol, thymol, and p-cymene are found in black cumin (Nigella sativa), a type of herb. This study reviewed 12 recent scientific publications to assess the antibacterial efficacy of N. sativa against clinical pathogenic microorganisms. A comprehensive literature review of in vitro, in silico studies, and applications was conducted. The study found that black cumin extract and oil were more efficient against Gram-positive bacteria such as Staphylococcus aureus than Gram-negative bacteria such as Escherichia coli and Salmonella typhi. The antibacterial activity increased with the concentration of the extract, especially in the polar form (ethanol). Active compounds such as thymoquinone also showed high binding affinity to MRSA bacterial proteins molecularly. The application of N. sativa in the form of ointments, antibacterial textiles, and dental health products also showed good effectiveness. Based on these findings, Nigella sativa has great potential as a safe and environmentally friendly natural antibacterial alternative, although further clinical studies are needed to validate its efficacy and safety.
Co-Authors Acivrida Mega Charisma Allyssia Salma Anwari, Farida Arif Rahman Nurdianto Bella Fevi Aristia Eviomitta Rizki Amanda Kadeq Novita Prajawanti Martina Kurnia Rohmah Widji Soeratri Yulianto Ade Prasetya