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DEVELOPMENT OF TOOTHPASTE FORMULATION MODEL OF MANALAGI APPLE PEEL EXTRACT (Malus Sylvetris) WITH DIFFERENT CONCENTRATIONS AGAINST THE GROWTH OF STREPTOCOCCUS BACTERIA MUTANS IN VITRO AND IN VIVO Risman Abdi Rapiuddin; Diyah Fatmasari; Arwani
Jurnal Health Sains Vol. 4 No. 7 (2023): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i7.996

Abstract

Background: Caries is a disease caused by damage to the enamel layer that can extend to the nerve part of the tooth. One way to prevent caries is to brush your teeth regularly using antibacterial herbal toothpaste that can reduce the number of colonies of streptococcus mutans bacteria. Apple peel is a useful herbal ingredient as an antibacterial, antioxidant, antifungal and antiproliferative, and polyphenolic compound. Objective: To determine the effect of developing a toothpaste formulation model of manalagi apple peel extract (malus sylvetris) with different concentrations on the growth of mutant Streptococcus bacteria in vitro and in vivo. Method: This study is a true experimental research using pre test and post test approach with control group design. Sampling was carried out using a simple random sampling technique and 15 respondents were obtained. This study was carried out for 3 days, where on the first day measurements were carried out (pretest) by taking saliva samples on respondents before brushing their teeth in the morning, and on the third day (posttest) measurements of respondents' saliva were carried out to test the bacterial colonies contained therein. Statistical analysis of Pre-Test Post-Test difference test using Paired T-Test difference test and One-Way Annova Test and Comparison Analysis with Post Hoc Tukey test. Results: This study showed that the dose of toothpaste in vitro testing was obtained the optimal dose, namely at the concentration of apple peel extract manalagi 25%, then in vivo tests the toothpaste formulation model of Manalagi apple peel extract (Malus Sylvetris) with the optimal dose (25%) was effective in inhibiting the growth of streptococcus mutans bacteria in vivo with an average decrease of -3.30 x 106 CFU / ml, with p value (0.005 < 0.05). control group + was -0.38 x 106 CFU/ml, and non-herbal toothpaste in control group - was -0.68 x 106 CFU/ml, but results Statistical analysis showed no significant difference in results before and after treatment in control group + (p value = 0.553 > 0.05) and control - (p value = 0.403 > 0.05). Conclusion: Manalagi apple peel extract toothpaste formulation model (malus sylvetris) with a concentration of 25% effective in inhibiting the growth of mutant Streptococcus bacteria in vitro and in vivo
ANALYSIS OF FACTORS AFFECTING THE PERFORMANCE OF POSBINDU NON-COMMUNICABLE DISEASES Ika Suciatmi; Arwani; Budi Widiyanto
Jurnal Health Sains Vol. 5 No. 1 (2024): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The cause of death of approximately 71% (36 million) people per year is due to non-communicable diseases. The 2018 Riskesdas data shows an increase in key NCD indicators. The significant increase in NCDs is expected to add to the burden on both the public and the government in healthcare financing. According to Government Regulation No. 71 of 2015, the prevention and control of NCDs are to be carried out through community health efforts and individual health efforts. The prevention and control of NCDs in the community are implemented through the activities of the NCD Posbindu. This research analyzes the factors affecting the performance of NCD Posbindu. The research method used is a Cross-Sectional approach with a quantitative method. The population consists of 486 NCD Posbindu, and the research sample uses Total Sampling, consisting of 29 NCD Posbindu. Data analysis includes univariate, bivariate (Spearman Rank), and multivariate (Multiple Linear Regression). The research results show that the majority of NCD Posbindu's performance falls into the "good" category, with 17 (58.62%), while the human resources (HR) are good in 19 (65.50%) cases, infrastructure is good in 12 (41.38%) cases, and the budget is good in 16 (53.20%) cases. Human resources, infrastructure, and the budget are positively and significantly correlated with the performance of NCD Posbindu, with correlation coefficients of HR (r=0.688), infrastructure (r=0.650), and the budget (r=0.598). The results of the Multiple Linear Regression test reveal that human resources, infrastructure, and the budget, when considered together, collectively affect the performance of NCD Posbindu, with an F value of 7.240, an adjusted R-squared value of 0.401, and a regression coefficient (β) of 18.799. Human resources, infrastructure, and the budget are related and significantly influence the performance of NCD Posbindu by 40.1%.
Potential of Honey Hydrogel Modern Dressing in Wound Healing of Patients with Grade II Diabetic Foot Ulcer Winda Afikirtiani; Arwani Arwani; Dwi Ari Murti Widigdo
Indonesian Contemporary Nursing Journal (ICON Journal) Vol. 8 No. 1 (2023): Volume 8 No. 1 Agustus 2023
Publisher : Faculty of Nursing, Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/icon.v8i1.28153

Abstract

Aims: To analyze the potential of honey hydrogel modern dressing in wound healing process in patients with grade II diabetic ulcers. Methods: The research design used a true experiment with a randomized pretest posttestcontrol group design. This study had 36 respondents who were divided into 2 groupsthrough simple random sampling. The intervention group was given honey hydrogel with 4measurements. The first measurement or pretest on day 1, the second measurement orposttest 1 on day 7, the third measurement or posttest 2 on day 14, and the fourthmeasurement or posttest 3 on day 21. The instrument used to measure patient woundhealing using the Bates-Jensen Wound Assessment Tool (BWAT). Results: The increase in the mean wound healing score of patients who were given honeyhydrogel modern dressing from a score of 42.11 on day 1 to 34.56 on day 21 with p = 0.001while the increase in the mean wound healing score of patients who were givenmanufacturer hydrogel modern dressing from a score of 41.67 on day 1 to 37.17 on day 21with p = 0.001. The effect size between the intervention group and the control group is quitestrong with a value of 0.78. Conclusion: Honey hydrogel has the potential to promote wound healing in patients withgrade II diabetic ulcers. Further research is recommended to explore the use of honeyhydrogel by innovating the manufacturing process to ensure consistent dosing in thetreatment of grade II diabetic ulcers.
Innovative warm blanket solution for inadvertent hypothermia among post-anesthesia patients Cahaya Nugraheni; Arwani Arwani; Sri Endang Windiarti
Malahayati International Journal of Nursing and Health Science Vol. 7 No. 3 (2024): Volume 7 Number 3
Publisher : Program Studi Ilmu Keperawatan-Fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v7i3.286

Abstract

Background: Shivering helps the body maintain its core temperature but can have harmful effects, such as increasing the oxygen demand in brain tissue. It frequently occurs in patients after anesthesia due to various factors. Purpose: To prove the effect of providing innovative warm blankets to treat shivering in post-anesthesia patients. Method: This quantitative quasi-experimental research with a pretest-posttest with control group design used purposive sampling to select 60 participants, who were divided into 2 groups: 30 participants in the treatment group and 30 participants in the control group. The treatment group received an intervention with an innovative warm blanket, while the control group received an intervention with a standard warm blanket according to the hospital's standard operating procedures. The measurement data were accumulated and analyzed using the Mann-Whitney test, and Cohen's effect size was used to assess the influence and differences between the innovative warm blanket and the standard hospital warm blanket. Results: The temperature in the intervention group, which received the innovative warm blanket treatment, rose by 2.050°C (p=0.001). In contrast, the temperature in the group that received the standard hospital warm blanket treatment increased by 1.80°C (p=0.001). Conclusion: Innovative warm blankets result in a greater temperature increase compared to the standard warm blankets used in accordance with hospital protocols.
The Effect of Leg Stretching Exercises with A Tennis Ball on Ankle Brachial Index as A Predictor of Diabetic Foot Ulcer Henny Yuliartini; Arwani Arwani; Budi Widiyanto
Indonesian Journal of Global Health Research Vol 6 No 4 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i4.3348

Abstract

Diabetic foot ulcers are caused by impaired peripheral circulation of the lower extremities due to peripheral arterial disease (PAD) that can be assessed by measuring the ankle brachial index. Leg stretching exercises with a tennis ball have an effect on increasing ABI values and predict the incidence of diabetic foot ulcers. Objective : This stydy aims to improve the effect of leg stretching exercises with a tennis ball on the ABI value as a predictor of the incidence of diabetic foot ulcers. Method: Quasi experimental quantitative research with a pretest-posttest with control group design. The total sample was 46 respondents using a purposive sampling technique to determine the Intervention group and Control group in 2 Puskesmas work areas that have plenary accreditation. After selecting each group, identification was carried out according to the inclusion criteria and exclusion criteria, resulting in 23 respondents in the Intervention group and 23 respondents in the Control group. The intervention group was given leg stretching exercises with a tennis ball for 15 minutes 14 times in 2 weeks and the control group received treatment from the Community Health Center, namely PROLANIS exercises. Data analysis uses univariate analysis and bivariate analysis, Paired Sample t-Test and Independent t-Test. Results: The ankle brachial index average increased to 0,300 mmHg and the prediction of the incidence of foot ulcers were decreased on the Intervention group (p=0,000) wheras the Control group ankle brachial index average decreased to 0,082 mmHg and the prediction of the incidence of foot ulcers were increased (p=0,008). Conclusion: Leg stretching exercises with a tennis ball have an effect on increasing ankle brachial index and can be used as a predictor of diabetic foot ulcers in type 2 diabetes mellitus.
Hydrogel Potential of Piper Crocatum (Piper Crocatum) Red Extract to Accelerate Perineum Wound Healing and Staphylococcus Aureus Bacteria Growth in Postpartum Shelvi Ovi Lestari; Krisdiana Wijayanti; Bedjo Santoso; Arwani Arwani; Suryati Kumorowulan
JURNAL KEBIDANAN Vol 14, No 1 (2024): April 2024
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v14i1.9185

Abstract

The prevalence of perineal rupture increases every year, as a result, the greater the chance of puerperal infection in postpartum mothers. Factors that cause puerperal infection is the care of the perineal wound that is not paid attention to. One of the complementary treatments uses herbal plants made from red betel leaf (Piper crocatum) in the form of hydrogel preparations. Proving the potential of red betel leaf hydrogel (Piper crocatum) against accelerated perineal wound healing and staphylococcus aureus bacterial growth. This type of quantitative research uses a quasi-experimental method with purposive sampling, post-test design only with control group. Sampling was in accordance with the inclusion criteria with a sample size of 45 respondents, 15 control respondents, 15 respondents to intervention I with a dose of 2x1 a day and 15 respondents to intervention II with a dose of 3x1 a day. Data was obtained from the REEDA score assessment scale which was obtained from the assessment of Redness, Edema (Swelling), Eccymosis (Bleeding), Discharge (Extraction) and Approximation (Wound union) and vaginal swab samples carried out on days 3 and 7 for 7 days. The analysis used to assess variables is the Wilcoxon and Mann Whitney tests. The analysis used to assess the variables is the Wilcoxon and Mann Whitney test. Red betel leaf hydrogel intervention 2x1 a day and intervention 3x1 a day has the potential to accelerate perineal wound healing and decrease the growth of S. aureus bacteria with p-value 0.05, so it can be interpreted that there is a significant difference effect. The greatest decreasing value in reducing the REEDA score and the growth of S. aureus bacteria was the 3x1 a day intervention group, namely 4.60 and 8.74, so it can be concluded that the 3x1 intervention was more effective than the 2x1 a day intervention.
The Effect of Family Empowerement in Preventing Stunting: Systematic Literature Review Suprihatin Suprihatin; Runjati Runjati; Arwani Arwani
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.4353

Abstract

Stunting is chronic malnutrition which is based on an index of body length compared to age (PB/U) or height compared to age (TB/U) with a limit (z-score) of less than -2 SD (Standard Deviation). Stunting problems need to be detected early, so that the interventions given can reduce long-term effects. Detection and management of stunting is carried out through empowerment efforts. Family empowerment as an effective step to reduce stunting cases through prevention and management efforts. The role of parents is very important in preventing stunting through detection and management. Anthropometric-based instruments that are easy to use are needed for the detection and management of stunting. Objective to analyze the variety of health promotion strategies to prevent stunting. The research design is a Systematic Literature Review of articles or journals published in 2018-2023, accessed on Google Scholar, PubMed and Scopus with the Prisma Flow technique. Research with different designs ranging from descriptive studies to quasi-experimental and participatory studies shows that an integrated and family-based approach can significantly improve knowledge, skills and awareness about stunting prevention. Programs involving education on exclusive breastfeeding, healthy food processing for toddlers, and maternal reproductive health have proven effective in reducing the prevalence of stunting. Health promotion strategies found in the literature review were mostly conceptual rather than operational and did not show when these strategies successfully reduced stunting.
Inovasi beras semar: Alternatif beras analog untuk manajemen glikemik bagi pasien diabetes melitus Arina Tina Salwa; Arina Rihadatulaisy Sabila; Afifah Salsabila; Arwani Arwani; Shobirun Shobirun; Suharto Suharto
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3A (2024): Agustus
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3A.1816

Abstract

Background: Diabetes mellitus is a non-communicable disease with increasing prevalence. Diabetes management through diet is a challenge, especially due to limited safe and nutritious food options. Semar Rice was developed as a solution to provide healthy food alternatives for people with diabetes.Objectives: The purpose of this research is to create an innovative food product in the form of analog rice from a combination of purple sweet potato, cinnamon, and milkfish bones as an alternative food for people with diabetes mellitus.Methods: This study used Research and Development method with laboratory testing for nutritional analysis. The research was conducted at the Food Nutrition and Health Laboratory of XYZ University from January to March 2024. Organoleptic tests were conducted on 10 healthy respondents aged 20-23 years. Three formulations were tested, namely A (35:35:30), B (60:20:20), and C (40:30:30). The glycemic index was tested by measuring the respondents' blood glucose response after consumption of 100 grams of Semar Rice compared to white rice.Results: Laboratory test results showed that sample A contained 56.88% carbohydrate, 6.03% fat, 12.26% protein, 2.82% glucose, and 3.35% sucrose. Semar rice with a portion of 297.4 grams had a glycemic index of 82.20 and a glycemic load of 49.78, although there were variations in results because some respondents did not follow the blood sugar check procedure. The organoleptic test showed a score of aroma 3, taste and texture 3.1, and color 3.5. Semar rice also meets SNI 6128-2015 standards for moisture and carbohydrate content.Conclusion: The conclusion of this study showed that Beras Semar has a low index glycemic compared to white rice. After doing Index Glycemic Test to 10 respondents, the result appear if the respondent’s glucose level more stable after consume Beras Semar than White Rice. KeywordsAnalog rice, diabetes mellitus, alternative food
How does coumarin work in insulin resistance for diabetes mellitus type 2? (A literature review) Arwani Arwani; Afifah Salsabila
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 4 (2025): Volume 8 Number 4
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i4.722

Abstract

Background: Coumarin is a natural compound found in various plants, including Cinnamomum cassia and Cinnamomum zeylanicum, and has been widely studied for its potential role in metabolic regulation, particularly in diabetes mellitus type 2. While coumarin has shown potential benefits in improving glycemic control, concerns regarding its hepatotoxic and carcinogenic effects remain. Purpose: To review the literature on how coumarin works in insulin resistance in people with type 2 diabetes. Method: A literature review was conducted using the ClinicalKey, Science Direct, and Google Scholar databases. Boolean operators (AND, OR, NOT) were used to refine the search. Inclusion criteria included research articles published between 2015 and 2024 in accredited national or internationally reputable journals, with a JBI critical appraisal tools score above 65%. The PRISMA diagram was used for article selection, resulting in five eligible articles for analysis. Results: The findings indicate that coumarin, predominantly found in cinnamon, has glucose-lowering effects in diabetes mellitus type 2 patients by reducing blood glucose levels, controlling glucose spikes, and lowering HbA1c. Additionally, coumarin derivatives in Opuntia ficus-indica and Smallanthus sonchifolius (yacon) may contribute to metabolic homeostasis through antioxidant activity. However, coumarin also poses hepatotoxic and carcinogenic risks at high doses. Conclusion: While coumarin-containing compounds show promise in improving glycemic control. Further research is needed to determine safe and effective therapeutic doses for clinical application.