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DEVELOPMENT OF TOOTHPASTE FORMULATION MODEL OF MANALAGI APPLE PEEL EXTRACT (Malus Sylvetris) WITH DIFFERENT CONCENTRATIONS AGAINST THE GROWTH OF STREPTOCOCCUS BACTERIA MUTANS IN VITRO AND IN VIVO Risman Abdi Rapiuddin; Diyah Fatmasari; Arwani
Jurnal Health Sains Vol. 4 No. 7 (2023): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i7.996

Abstract

Background: Caries is a disease caused by damage to the enamel layer that can extend to the nerve part of the tooth. One way to prevent caries is to brush your teeth regularly using antibacterial herbal toothpaste that can reduce the number of colonies of streptococcus mutans bacteria. Apple peel is a useful herbal ingredient as an antibacterial, antioxidant, antifungal and antiproliferative, and polyphenolic compound. Objective: To determine the effect of developing a toothpaste formulation model of manalagi apple peel extract (malus sylvetris) with different concentrations on the growth of mutant Streptococcus bacteria in vitro and in vivo. Method: This study is a true experimental research using pre test and post test approach with control group design. Sampling was carried out using a simple random sampling technique and 15 respondents were obtained. This study was carried out for 3 days, where on the first day measurements were carried out (pretest) by taking saliva samples on respondents before brushing their teeth in the morning, and on the third day (posttest) measurements of respondents' saliva were carried out to test the bacterial colonies contained therein. Statistical analysis of Pre-Test Post-Test difference test using Paired T-Test difference test and One-Way Annova Test and Comparison Analysis with Post Hoc Tukey test. Results: This study showed that the dose of toothpaste in vitro testing was obtained the optimal dose, namely at the concentration of apple peel extract manalagi 25%, then in vivo tests the toothpaste formulation model of Manalagi apple peel extract (Malus Sylvetris) with the optimal dose (25%) was effective in inhibiting the growth of streptococcus mutans bacteria in vivo with an average decrease of -3.30 x 106 CFU / ml, with p value (0.005 < 0.05). control group + was -0.38 x 106 CFU/ml, and non-herbal toothpaste in control group - was -0.68 x 106 CFU/ml, but results Statistical analysis showed no significant difference in results before and after treatment in control group + (p value = 0.553 > 0.05) and control - (p value = 0.403 > 0.05). Conclusion: Manalagi apple peel extract toothpaste formulation model (malus sylvetris) with a concentration of 25% effective in inhibiting the growth of mutant Streptococcus bacteria in vitro and in vivo
ANALYSIS OF FACTORS AFFECTING THE PERFORMANCE OF POSBINDU NON-COMMUNICABLE DISEASES Ika Suciatmi; Arwani; Budi Widiyanto
Jurnal Health Sains Vol. 5 No. 1 (2024): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The cause of death of approximately 71% (36 million) people per year is due to non-communicable diseases. The 2018 Riskesdas data shows an increase in key NCD indicators. The significant increase in NCDs is expected to add to the burden on both the public and the government in healthcare financing. According to Government Regulation No. 71 of 2015, the prevention and control of NCDs are to be carried out through community health efforts and individual health efforts. The prevention and control of NCDs in the community are implemented through the activities of the NCD Posbindu. This research analyzes the factors affecting the performance of NCD Posbindu. The research method used is a Cross-Sectional approach with a quantitative method. The population consists of 486 NCD Posbindu, and the research sample uses Total Sampling, consisting of 29 NCD Posbindu. Data analysis includes univariate, bivariate (Spearman Rank), and multivariate (Multiple Linear Regression). The research results show that the majority of NCD Posbindu's performance falls into the "good" category, with 17 (58.62%), while the human resources (HR) are good in 19 (65.50%) cases, infrastructure is good in 12 (41.38%) cases, and the budget is good in 16 (53.20%) cases. Human resources, infrastructure, and the budget are positively and significantly correlated with the performance of NCD Posbindu, with correlation coefficients of HR (r=0.688), infrastructure (r=0.650), and the budget (r=0.598). The results of the Multiple Linear Regression test reveal that human resources, infrastructure, and the budget, when considered together, collectively affect the performance of NCD Posbindu, with an F value of 7.240, an adjusted R-squared value of 0.401, and a regression coefficient (β) of 18.799. Human resources, infrastructure, and the budget are related and significantly influence the performance of NCD Posbindu by 40.1%.
Hydrogel Potential of Piper Crocatum (Piper Crocatum) Red Extract to Accelerate Perineum Wound Healing and Staphylococcus Aureus Bacteria Growth in Postpartum Shelvi Ovi Lestari; Krisdiana Wijayanti; Bedjo Santoso; Arwani Arwani; Suryati Kumorowulan
JURNAL KEBIDANAN Vol 14, No 1 (2024): April 2024
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v14i1.9185

Abstract

The prevalence of perineal rupture increases every year, as a result, the greater the chance of puerperal infection in postpartum mothers. Factors that cause puerperal infection is the care of the perineal wound that is not paid attention to. One of the complementary treatments uses herbal plants made from red betel leaf (Piper crocatum) in the form of hydrogel preparations. Proving the potential of red betel leaf hydrogel (Piper crocatum) against accelerated perineal wound healing and staphylococcus aureus bacterial growth. This type of quantitative research uses a quasi-experimental method with purposive sampling, post-test design only with control group. Sampling was in accordance with the inclusion criteria with a sample size of 45 respondents, 15 control respondents, 15 respondents to intervention I with a dose of 2x1 a day and 15 respondents to intervention II with a dose of 3x1 a day. Data was obtained from the REEDA score assessment scale which was obtained from the assessment of Redness, Edema (Swelling), Eccymosis (Bleeding), Discharge (Extraction) and Approximation (Wound union) and vaginal swab samples carried out on days 3 and 7 for 7 days. The analysis used to assess variables is the Wilcoxon and Mann Whitney tests. The analysis used to assess the variables is the Wilcoxon and Mann Whitney test. Red betel leaf hydrogel intervention 2x1 a day and intervention 3x1 a day has the potential to accelerate perineal wound healing and decrease the growth of S. aureus bacteria with p-value 0.05, so it can be interpreted that there is a significant difference effect. The greatest decreasing value in reducing the REEDA score and the growth of S. aureus bacteria was the 3x1 a day intervention group, namely 4.60 and 8.74, so it can be concluded that the 3x1 intervention was more effective than the 2x1 a day intervention.
Inovasi beras semar: Alternatif beras analog untuk manajemen glikemik bagi pasien diabetes melitus Arina Tina Salwa; Arina Rihadatulaisy Sabila; Afifah Salsabila; Arwani Arwani; Shobirun Shobirun; Suharto Suharto
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3A (2024): Agustus
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3A.1816

Abstract

Background: Diabetes mellitus is a non-communicable disease with increasing prevalence. Diabetes management through diet is a challenge, especially due to limited safe and nutritious food options. Semar Rice was developed as a solution to provide healthy food alternatives for people with diabetes.Objectives: The purpose of this research is to create an innovative food product in the form of analog rice from a combination of purple sweet potato, cinnamon, and milkfish bones as an alternative food for people with diabetes mellitus.Methods: This study used Research and Development method with laboratory testing for nutritional analysis. The research was conducted at the Food Nutrition and Health Laboratory of XYZ University from January to March 2024. Organoleptic tests were conducted on 10 healthy respondents aged 20-23 years. Three formulations were tested, namely A (35:35:30), B (60:20:20), and C (40:30:30). The glycemic index was tested by measuring the respondents' blood glucose response after consumption of 100 grams of Semar Rice compared to white rice.Results: Laboratory test results showed that sample A contained 56.88% carbohydrate, 6.03% fat, 12.26% protein, 2.82% glucose, and 3.35% sucrose. Semar rice with a portion of 297.4 grams had a glycemic index of 82.20 and a glycemic load of 49.78, although there were variations in results because some respondents did not follow the blood sugar check procedure. The organoleptic test showed a score of aroma 3, taste and texture 3.1, and color 3.5. Semar rice also meets SNI 6128-2015 standards for moisture and carbohydrate content.Conclusion: The conclusion of this study showed that Beras Semar has a low index glycemic compared to white rice. After doing Index Glycemic Test to 10 respondents, the result appear if the respondent’s glucose level more stable after consume Beras Semar than White Rice. KeywordsAnalog rice, diabetes mellitus, alternative food
How does coumarin work in insulin resistance for diabetes mellitus type 2? (A literature review) Arwani Arwani; Afifah Salsabila
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 4 (2025): Volume 8 Number 4
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i4.722

Abstract

Background: Coumarin is a natural compound found in various plants, including Cinnamomum cassia and Cinnamomum zeylanicum, and has been widely studied for its potential role in metabolic regulation, particularly in diabetes mellitus type 2. While coumarin has shown potential benefits in improving glycemic control, concerns regarding its hepatotoxic and carcinogenic effects remain. Purpose: To review the literature on how coumarin works in insulin resistance in people with type 2 diabetes. Method: A literature review was conducted using the ClinicalKey, Science Direct, and Google Scholar databases. Boolean operators (AND, OR, NOT) were used to refine the search. Inclusion criteria included research articles published between 2015 and 2024 in accredited national or internationally reputable journals, with a JBI critical appraisal tools score above 65%. The PRISMA diagram was used for article selection, resulting in five eligible articles for analysis. Results: The findings indicate that coumarin, predominantly found in cinnamon, has glucose-lowering effects in diabetes mellitus type 2 patients by reducing blood glucose levels, controlling glucose spikes, and lowering HbA1c. Additionally, coumarin derivatives in Opuntia ficus-indica and Smallanthus sonchifolius (yacon) may contribute to metabolic homeostasis through antioxidant activity. However, coumarin also poses hepatotoxic and carcinogenic risks at high doses. Conclusion: While coumarin-containing compounds show promise in improving glycemic control. Further research is needed to determine safe and effective therapeutic doses for clinical application.
APLIKASI HASIL PENELITIAN PELATIHAN DAN PENERAPAN AKUPRESUR UNTUK MENINGKATKAN DAYA TAHAN TUBUH DAN MENGURANGI KECEMASAN PADA IBU HAMIL DAN MENOPOUSE PADA ERA ADAPTASI COVID 19 Dina Indrati Dyah Sulistyowati; Arwani Arwani; Nina Indriyawati; Wien Soelistyo Adi; Mardiyono Mardiyono
Jurnal Pengabdian Ilmu Kesehatan Vol. 2 No. 3 (2022): November: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v2i3.841

Abstract

Kasus positif Covid 19 pada perempuan ibu hamil. Melahirkan dan nifas di Indonesia terdapat puluhan sampai ratusan kasus. Meningkatnya kasus covid 19 menjadikan kebutuhan informasi dan pengetahuan yang baik bagi petugas dan keluarganya akan penatalaksanaan kasus maternal dan menapouse dengan covid 19. Dengan meningkatnya kembali kasus covid dengan klister baru membawa dampak tersendiri bagi masyarakat terutama ibu hamil dan lansia. Terutama rasa cemas menghadapi kondisi tersebut. Rasa cemas yang timbul akan berdampak pada turunnya imun seseorang sehingga akan rentan tertular virus. Salah satu cara untuk meningkatkan imun dan mengurangi kecemasan yaitu dengan penerapan acupressure. Akupresur adalah salah satu terapi komplementar merupakan perpaduan antara self healing dan akupresur, dimana proses pemijatan mempunyai 2 reaksi, yaitu reaksi menguatkan (yang) dan reaksi menurunkan (yin). Pijatan-pijatan pada titik tertentu dalam terapi akupresur dapat merangsang gelombang syaraf sehingga mampu melancarkan aliran darah, merelaksasikan spasme, dan meningkatkan imun. Tujuan pengabdian masyarakat ini adalah untuk menerapkan hasil penelitian sebelumnya tentang Akupresur Untuk Meningkatkan Daya Tahan Tubuh Dan Mengurangi Kecemasan Pada Ibu Hamil Dan Menopouse Pada Era Adaptasi Covid 19 ”. Metode pengabdian masyarakat ini dengan menyelenggarakan pelatihan cara acupressure mandiri secara langsung maupun media online dan demostrasi. Hasil pengabdian masyarakat ini diharapkan dapat sebagai standar operasional dalam membantu meningkatkan pengetahuan masyarakat tetang cara acupressure untuk meningkatkan daya tahan tubuh dan menurunkan kecemasan di masa pandemic saat ini.
Efektivitas Ekstra Moringa Oleifera Dengan Konsentrasi Dosis Yang Berbeda Terhadap Produksi ASI Ibu Menyusui Sri Lestari; Arwani Arwani; Irmawati Irmawati
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.43062

Abstract

The consumption of herbal foods is known to enhance breast milk production in breastfeeding mothers. Therefore, researchers have innovated to improve breast milk production by comparing the administration of Moringa Oleifera extract at various dosages. Objective: The study was to evaluate the effectiveness of Moringa Oleifera extract with different dose concentrations on breast milk production in breastfeeding mothers. Method: This study employed a Kuasi experimental design with a pretest-posttest approach, consisting of three groups. The population included all breastfeeding mothers in the Pagerbarang Health Center Work Area, Tegal Regency, with a sample size of 20 respondents in each group. Interventions involved administering Moringa Oleifera extract at doses of 250 mg, 650 mg, and 800 mg for 14 days. Bivariate analysis was conducted using the Paired Sample T-Test and Wilcoxon test. Results: There was no difference in the increase in breast milk production of breastfeeding mothers based on the category of baby's weight, bowel movements and urination (p> 0.05) after administration of moringa oleifera extract capsules at doses of 250 mg, 650 mg and 800 mg. The dose of 650 was more effective in increasing baby's weight and the dose of 250 was more effective in increasing breast milk production based on the category of baby's bowel movements and urination. Conclusion: The administration of Moringa Oleifera extract capsules at various doses effectively enhances breast milk production in breastfeeding mothers.
Increasing the Role of Fostered Kader in the Stunting Prevention Program in the Boja 2 Community Health Center, Boja District, Kendal Regency Ahmad Riadi; Riskiyana Sukandhi Putra; Arwani; Tri Wiji Lestari
Wealth Community Empowerment Vol. 3 No. 1 (2026): January 2026
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/welcomejournal.v3i1.14520

Abstract

Stunting is a condition of growth failure in children, characterized by impaired physical growth and cognitive development due to long-term chronic malnutrition. This condition occurs from the fetal period through early childhood, commonly referred to as the first 1,000 days of life. Preventing stunting requires the involvement of multiple stakeholders, including the active role of adolescents as agents of change within the community. This community service program aimed to enhance adolescents’ capacity for early detection of stunting and to strengthen collaboration with primary health centers in addressing stunting. The methods included health education, capacity building for adolescent cadres, and cross-sector collaboration with community health centers. The results showed that adolescent cadres, in collaboration with partners, were able to implement iron supplementation (iron tablets) programs for elementary, junior high, and senior high school students. In addition, adolescent cadres actively provided education to parents and adolescents on adequate nutrition and early stunting prevention. This program is expected to serve as a sustainable strategy to support the acceleration of stunting reduction in the community.
Meningkatkan Keselamatan Pasien dalam Deteksi Dini Perburukan Kondisi Fisiologis Pasien Menggunakan National Early Warning Score (NEWS) Irmalita Wigati; Arwani Arwani; Martha Cintia Dewi
Jurnal Kepemimpinan dan Manajemen Keperawatan Vol. 3 No. 2 (2020)
Publisher : Persatuan Perawat Nasional Indonesia Jawa Tengah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32584/jkmk.v3i2.639

Abstract

Early Warning System (EWS) adalah suatu sistem yang umumnya digunakan di unit medikal bedah untuk mengatasi masalah kesehatan pasien secara dini, didasarkan atas penilaian terhadap perubahan keadaan pasien melalui pengamatan yang sistematis terhadap semua perubahan fisiologi pasien dan merupakan konsep pendekatan proaktif untuk meningkatkan keselamatan pasien dan hasil klinis pasien yang lebih baik dengan standarisasi pendekatan asesmen dan menetapkan skoring parameter fisiologis yang sederhana. Tujuan studi ini adalah mengidentifikasi penerapan National Early Warning Score (NEWS) untuk deteksi dini perburukan kondisi pasien melalui kajian literatur. Kajian pustaka telah dilakukan melalui database jurnal PubMed, Proquest dan EBSCO. Kata kunci yang digunakan yaitu National Early Warning System AND Deterioration. Kriteria inklusi yang ditetapkan adalah artikel yang dipublikasikan dalam rentang 5 tahun terakhir, tipe artikel clinical trial, journal article, randomized controlled trial, human, best match, full text. Kriteria eksklusi dari sumber referensi yang diambil yaitu artikel yang isinya tidak lengkap, referensinya tidak jelas serta artikel yang tidak sesuai topik. Data dianalisis berisi judul, penulis, tahun, metodologi, dan hasil. Peneliti mengidentifikasi 44 judul dan disaring menjadi 5 artikel yang membahas NEWS untuk deteksi dini perburukan kondisi pasien. Hasil penelitian menunjukkan penerapan NEWS dapat meningkatkan monitoring vital sign 95 %, membantu perawat untuk mendeteksi perubahan kondisi pasien dan sebagai alat bantu dalam berkomunikasi dengan petugas kesehatan lainnya. NEWS merupakan sistem skoring yang sederhana, praktis dan terbukti dapat meningkatkan kewaspadaan dan respon terhadap tanda-tanda perubahan fisiologis yang buruk sehingga keselamatan pasien dapat dipantau secara optimal dan angka mortalitas dapat menurun
Efektivitas Nanopartikel Bayam Merah (Amaranthus Tricolor L.) Terhadap Kadar Hormon Prolaktin dan Produksi Asi Pada Ibu Menyusui Nawang Setyoningrum; Krisdiana Wijayanti; Arwani Arwani
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.55830

Abstract

Exclusive breastfeeding period is a vulnerable period for breast milk (ASI) sufficiency to meet infant nutritional needs. Red spinach (Amaranthus tricolor L.) contains galactagogue compounds that have the potential to increase breast milk production by increasing prolactin levels. Objective: To determine the effectiveness of red spinach (Amaranthus tricolor L.) nanoparticles on prolactin levels and breast milk production in breastfeeding mothers. Method: This study employed a quasi-experimental design with a pretest–posttest control group design. The sample consisted of 32 breastfeeding mothers divided into two groups, with 16 participants in the intervention group and 16 in the control group, recruited from Mangunsari Primary Health Center and a private midwifery clinic (BPM Ibu Alam), as well as Sidorejo Kidul Primary Health Center, Salatiga. The intervention group received red spinach nanoparticles at a dose of 250 mg for 14 days, while the control group received breastfeeding education. Breast milk production was assessed indirectly using infant weight gain, whereas prolactin hormone levels were measured using the ELISA method. Data were analyzed using the Wilcoxon test, Paired Sample T Test, Mann–Whitney test, Repeated Measures ANOVA, and Independent t-test. Results: Administration of red spinach nanoparticles significantly increased prolactin levels in the intervention group (p = 0.013), whereas no significant change was observed in the control group (p = 0.955). Infant weight gain occurred in both the intervention and control groups (p<0.000); however, no statistically significant difference was found between the two groups. Conclusion: Red spinach nanoparticles at a dose of 250 mg administered for 14 days were effective in increasing prolactin levels in breastfeeding mothers. This intervention has the potential to support breast milk production, as indicated by infant weight gain, although no significant difference was observed compared to the control group