Claim Missing Document
Check
Articles

Found 13 Documents
Search

Candidates for antimalarial compounds in secondary metabolites of Streptomyces sp. InaCC 1497 and AB8 Endah Setyaningrum; Jihan Fikra Angelia; Kusuma Handayani; Achmad Arifiyanto; Dzul Fithria Mumtazah
Biogenesis: Jurnal Ilmiah Biologi Vol 11 No 1 (2023)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v11i1.33727

Abstract

One effort to reduce the transmission of malaria is the provision of antimalarial drugs. However, the use of drugs that are not according to standards causes resistance to Plasmodium. This condition triggers the exploration of various natural compounds to prevent malaria. Secondary metabolites derived from Streptomyces sp. are known to have antimalarial activity. However, information related to secondary metabolites from Streptomyces sp. strains InaCC A497 and AB8 as antimalarials are not yet known. The purpose of this study was to determine the metabolite compounds secondary contained in Streptomyces sp. strains InaCC A497 and AB8 as antimalarial candidates. This research method is descriptive by testing secondary metabolites which are carried out through chemical compound tests, thin layer chromatography (TLC), fourier transform infra-red (FT-IR), and gas chromatography-mass spectroscopy (GC-MS). Test results of chemical compounds and FT-IR analysis of Streptomyces sp. InaCC A497 contains alkaloids, flavonoids, and triterpenoids, while Streptomyces sp. AB8 contains alkaloids and tannins. In the TLC test, Streptomyces sp. InaCC A497 produced an Rf value of 0.257 and Streptomyces sp. AB8 of 0.314. Based on the GC-MS test, Streptomyces sp. InaCC A497 produces acetic acid compounds, ethyl ester including the ester group, and 1,2-benzene dicarboxylic acid, dioctyl ester including the alkaloid group. Streptomyces sp. AB8 produces the compound 2-pentadecyn-1-ol which belongs to the aromatic alcohol group and cochlioquinone A belongs to the quinone group. Both compounds have antimalarial activity.
Optimalisasi Produk Berbahan Dasar Pepaya Di Desa Karang Sari Dusun IV B Kecamatan Jati Agung Lampung Selatan Yulianty; Emantis Rosa; Sri Wahyuningsih; Achmad Arifiyanto
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 9 : Oktober (2023): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Papaya is one of the most widely cultivated plants in Indonesia. People generally use all parts of papaya in their daily lives, but not optimally yet, mainly only used as food and less varied While other parts such as fruit skin, seeds, and stems generally be thrown away as garbage. The skin and leaves could be used as liquid organic fertilizer and bio fungicide. Therefore, it is necessary to make an effort to optimize products from papaya plants in the community of Karang Sari Village IVB. This Community Service was carried out with the aim of knowing the utilization and increasing knowledge and practice of papaya plants. The results of the service obtained were the average pre-test score of 49.47 and the average post-test score of 95.79. There was an increase in points of 46.32. Further expectations in this service that the people in Karang Sari Village IV B can utilize papaya plants more varied and diverse.
Pelatihan Pembuatan Spesimen Awetan Tumbuhan Dan Hewan Sebagai Media Pembelajaran Dalam Mengungkap Keanekaragaman Hayati Yulianty; M Kanedi; Kusuma Handayani; Achmad Arifiyanto
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 7 : Agustus (2023): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Learning media is one of the methods used in the learning process and is highly needed in facilitating material delivery. In presenting biology materials, such as biodiversity, attractive media is crucial in helping students understand without excessive memorization. Preserved specimen is an example of learning media in this situation. Wet and dry herbariums are one of the preserved specimens commonly used by teachers. Meanwhile, bioplastic creation using resin has not been a common practice. Some advantages of bioplastic creation include more beautiful and durable results while also can be created as keychains. The aim of this community service is to train teachers in SMA 15 Bandar Lampung in making animal and plant preserved specimens through various procedures. After the training, there was an increase in knowledge and skill in making preserved specimens. The average pre-test score was 56.25, while the average post-test was 90,63. The average score escalated by 34,38 points.