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All Journal Jurnal Kedokteran Brawijaya Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Bulletin of Electrical Engineering and Informatics Medical Journal of Indonesia Berkala Ilmu Kesehatan Kulit dan Kelamin Indonesian Journal of Biotechnology Indian Journal of Forensic Medicine & Toxicology Berita Kedokteran Masyarakat Journal of Clinical Microbiology and Infectious Diseases
Hardyanto Soebono
Department Of Dermatology And Venereology, Faculty Of Medicine, Public Health, And Nursing Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta
Biochemistry, Genetics & Molecular Biology Electrical & Electronics Engineering Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Medical Journal of Indonesia

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Lepromatous leprosy mimicking systemic lupus erithematosus: a case report Kusumaningrum, Niken; Purnamawati, Schandra; Winarni, Dwi Retno Adi; Soebono, Hardyanto
Medical Journal of Indonesia Vol 28, No 1 (2019): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (7167.123 KB) | DOI: 10.13181/mji.v28i1.1793

Abstract

The clinical manifestations of leprosy are highly variable, and the disease is notorious for being “a great imitator” of several other conditions. Leprosy may manifest with a variety of phenomena resembling those of autoimmune diseases. Herein, we report a 33-year-old male presenting with wounds on his left leg and hyperpigmented skin lesions all over his body. Six years earlier, the patient was diagnosed with systemic lupus erythematosus (SLE). However, therapy for SLE did not control his symptoms; instead, the patient developed features of leprosy, such as anesthetic skin lesions, nerve enlargement, and tenderness. Tests for antinuclear antibodies and anti-double stranded DNA antibodies were negative. Slit-skin smear showed a bacterial index of 6+ and morphological index of 10 %. Lupus band test results were negative. Histological findings were compatible with lepromatous leprosy. The clinical and serological similarities between leprosy and SLE may lead to erroneous diagnosis. Thus, clinicians should be aware of this characteristic for correct diagnosis.
Co-Authors . Fitria Amaia, Devika N. Aminy, Sayyidah A. Anang Endaryanto Aprizal Aprizal Arief Kelik Nugroho, Arief Kelik Budi Prasetyo Cita Rosita Sigit Prakoeswa Dewi Kartikawati Paramita Dewi, Shinta Trilaksmi Dominicus Husada Efrizal Efrizal Erinda Maharani Rambu Moha Fajar Waskito Flora Ramona Sigit Prakoeswa Gilang Baswara H. Bing Thio Hari Basuki Notobroto Herwinda Brahmanti Ida Tjahajati Iryani Andamari Ishandono Dachlan Iwan Dwiprahasto Lutfan Lazuardi M. Yulianto Listiawan Mae Sri Hartati Wahyuningsih Maria Sophiati Marsetyawan HNE Soesatyo Moh Hakimi Niken Indrastuti Niken Kusumaningrum Niken Trisnowati Ning Rintiswati Ning Rintiswati Oktarina, Dyah Ayu Mira Purnamawati, Schandra Retantyo Wardoyo Saihas Sauda Santi Martini Satiti Retno Pudjiati Satiti Retno Pudjiati Teguh Aryandono Titik Nuryastuti Tri Wibawa Wibowo, Moh Edi Widya Asmara Winarni, Dwi Retno Adi Yohanes Widodo Wirohadidjojo Zubairi Djoerban