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Pengembangan dan Evaluasi Stabilitas Formulasi Gel yang Mengandung Etil p-metoksisinamat Nelly Suryani; Deani Nurul Mubarika; Ismiarni Komala
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 1, No 1 (2019)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.899 KB) | DOI: 10.15408/pbsj.v1i1.12688

Abstract

Etil p-metoksisinamat (EPMS) merupakan senyawa utama aktif anti-inflamasi yang terdapat dalam rimpang kencur (Kaempferia galanga). Tujuan penelitian ini adalah  untuk mengembangkan sediaan gel yang mengandung EPMS dengan menggunakan kombinasi HPMC dan karbopol 940 sebagai gelling agent. Sediaan gel di buat dalam tiga formula F1, F2 dan F3 dengan variasi persentase kombinasi HPMC : karbopol 940 yang digunakan masing-masingnya adalah 0,4 : 0,4%, 0,5 : 0,5%, dan 1.0 : 0,5%. Masing-masing formula selanjutnya  dievaluasi  sifat fisik dan kimianya. Hasil evaluasi fisik menunjukkan bahwa secara organoleptis ketiga formula F1, F2 dan F3 memenuhi syarat sediaan gel, serta stabil ketika dilakukan  pengujian sentrifugasi dan cycling test. Formuala F2 merupakan sediaan terbaik dalam pembuatan sediaan gel EPMS. Evaluasi stabilitas kimia menunjukkan bahwa kadar EPMS dalam sediaan gel hari ke- 0, 7, 14, dan 21 berada dalam rentang 91–100%. Sediaan gel mengalami penurunan kadar EPMS masing-masingnya sebesar 9% (F1), 5% (F2) dan 6%, (F3).
DAMPAK PANDEMI TERHADAP UMKM DI DESA UJUNG JAYA KABUPATEN SUMEDANG Adelse Prima Mulya; Siti Mutia Kosassy; Nelly Suryani; Yurismen Efendi
Jurnal Public Administration, Business and Rural Develoment Planning Vol 4 No 2 (2022): Jurnal Public Administration, Business and Rural Development Planning
Publisher : Jurnal Public Administration, Business and Rural Development Planning

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The COVID-19 pandemic has hit the world, including Indonesia, and has had various impacts, including MSMEs. This study aims to determine the impact of Covid-19 on the UMKM of Ujung Jaya Village at this time. This type of research is descriptive qualitative by using secondary data from research results and literature references regarding data and information related to research. The results of this study show the impact of the Covid-19 pandemic on MSMEs, the challenges of MSMEs during the Covid 19 Pandemic and the MSMEs Strategy in dealing with Covid 19 in Ujung Jaya Village. The impact of the pandemic in Ujung Jaya Village is quite strong, many MSME players have suffered losses due to a decrease in people's purchasing power and a reduction in the production process. It is recommended that to overcome the impact of the pandemic in Ujung Jaya Village, MSME actors can switch to the concept of going digital with the use of social media and other e-commerce to revive their MSME movement
Analysis of the Entrapment Efficiency of Thymoquinone in Microcapsules of Black Cumin Seed Oil (Nigella sativa L.) Using High Performance Liquid Chromatography Ofa Suzanti Betha; Supandi, Supandi; Addina Syahida; Boy Reynaldi Noor; Nelly Suryani; Sabrina Dahlizar; Yuni Anggraeni; Barita J. Siregar; Zilhadia
Journal of Fundamental and Applied Pharmaceutical Science Vol. 6 No. 1 (2025): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v6i1.27545

Abstract

Thymoquinone is the main active compound found in black cumin seed oil (Nigella sativa). This study intends to analyze the efficiency of its absorption in microcapsules by the ionic gelation of cross-linked alginate and the CaCl2 method, and loading with black cumin seed oil in a concentration of 20%. Thymoquinone was used as a marker to establish quality standards for this microcapsule preparation. Analysis of thymoquinone in microcapsules was performed using a pre-optimized, high-performance liquid chromatography method. Method optimization utilized an Acclaim® Polar Advantage II (C18) column with a flow speed of 1.5 mL/min, a UV detector wavelength of 252 nm, and an injection volume of 20 μL with an isocratic system on a methanol eluent composition: water (70:30). This method revealed a good linearity value (r = 0.9997) in the range of 0.5 – 500 μg/ml. The detection and quantitation limits were 8.67 μg/mL and 28.9 μg/mL, (%diff) was about -1.864 to 1.562, precision (% RSD) was 0.052 to 0.113%, and the recovery was 98.135 to 101.563%. The results of this method validation were then applied to determine thymoquinone loading in black cumin seed oil microcapsules. The results of the absorption efficiency value of black cumin seed oil microcapsules by the ionic gelation alginate and CaCl2 method, which contained 20% oil concentration in the formula, were 81.769%.
Analysis of the Impact of Digital Marketing on Sales Growth of Lampung Tapis Handicraft MSMEs in the Digital Economy Era Supri Yanto; Putri Irmala Sari; Nelly Suryani
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.4528

Abstract

The study purpose was. This study aims to analyze the impact of digital marketing on the sales growth of Lampung Tapis handicraft micro, small, and medium enterprises (MSMEs) in the digital economy era. Despite the increasing adoption of digital marketing by traditional MSMEs, empirical evidence regarding its effectiveness in enhancing sales performance remains limited, particularly for culturally significant products such as Tapis handicrafts. Materials and methods. The study adopts a quantitative methodology, relying on primary data gathered via structured questionnaires administered to 50 Tapis MSME owners who are actively involved in digital marketing. Secondary sales data from the Cooperative and MSME Office of Lampung Province (2020–2023) further support the analysis. Statistical methods, including linear regression via SPSS, are applied to examine the relationship between digital marketing strategies. Results. The findings reveal a significant positive correlation between digital marketing adoption and sales growth, with a notable 35% average increase post implementation. Social media platforms, particularly Instagram and Facebook, emerge as the most influential drivers, outperforming marketplace based strategies. Key success factors include content creativity, customer engagement, and consistent promotional frequency. Conclusions. This study contributes to the digital marketing literature by validating the Technology Acceptance Model (TAM) in the context of traditional handicraft MSMEs, emphasizing the role of perceived usefulness and ease of use in technology adoption. Its originality lies in focusing on a culturally unique sector Lampung Tapis which has been underexplored in prior studies. Practical implications suggest the need for targeted government-led digital training programs and collaborations with local influencers to optimize MSMEs’ digital presence.