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All Journal e-Journal Pustaka Kesehatan Jurnal Pangan dan Agroindustri STOMATOGNATIC- Jurnal Kedokteran Gigi UNEJ e-Proceeding Dentino: Jurnal Kedokteran Gigi Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Journal of Innovation Research and Knowledge
Ari Tri Wanodyo Handayani
Faculty Of Dentistry, Universitas Jember, Jember
Agriculture, Biological Sciences & Forestry Humanities Dentistry Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Social Sciences

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Journal : e-Journal Pustaka Kesehatan

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Efektivitas Ekstrak Black Garlic dalam Menghambat Pertumbuhan Candida albicans Ratih Iswari Ningtias; Dyah Indartin Setyowati; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 8 No 3 (2020): Volume 8 No. 3, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i3.12990

Abstract

Black garlic has many properties naturally can be used as an antifungi. This study aims to determine the effectiveness of Black garlic extract in inhibiting the growth of Candida albicans and knowing the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of Black garlic extract against Candida albicans. This study used 5 groups of Black garlic extract concentration, namely 75%, 50%, 25%, 12.5%, and positive controls, with 5 replications. Extraction was carried out using maceration method with 96% ethanol solvent, while the antifungal test was carried out by liquid dilution method. MIC was determined by observing the turbidity and clarity of each test solution and compared to the control solution. MFC was determined by observing the presence or absence of fungi colonies growing on Sabouraud Dextrosa Agar (SDA) media after incubation for 24 hours. The results of the study carried out the Kruskall-Wallis test showed a significance value (p <0.05) which means that there were significant differences in all groups. In the Mann-Whitney test showed a significance value (p <0.05) which means there are differences between treatment groups. The conclusion is that Black garlic extract has the ability to antifungal with MIC at a concentration of 50% and MFC at a concentration of 75%.
Hubungan Tingkat Kebersihan Gigi dan Mulut dengan Karies pada Nelayan di Pesisir Pantai Watu Ulo Kabupaten Jember Yona Anindita; Kiswaluyo Kiswaluyo; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.8654

Abstract

Activity to cleanse and refresh the teeth and mouth is oral hygiene. Caries and periodontal disease will occure if not treating well, so they need to do the treatment to maintain the oral health. Fishermen usually sail in the afternoon and return in the next morning, sometimes they stay in the sea for a day. This situation causes the lack of attention of oral hygiene and increases the occurrence of dental caries. Researcher interests to analyze the relationship of oral hygiene levels with the caries of fishermen at Dusun Watu Ulo, Sumberejo Village, Jember District, East Java. This study performs oral hygiene examination using OHI-S index and caries examination using DMF-T index. This study aimed to determine the relationship between the level of oral hygiene with caries in fishermen at the coast of Watu Ulo Beach, Jember District.This observational analytic research was conducted by cross sectional approach. The method for sampling used Cluster Sampling. he average score of OHI-S fishermen at Watu Ulo coastal Jember District was 3.90 (bad category) and the average DMF-T index score was 3.10 (medium category). There was a weak relationship between oral hygiene with caries. Keywords: Oral hygiene, Caries, OHI-S, DMF-T, Fishermen.
Kadar Kolesterol pada Mencit (Mus-Musculus) Diabetes Setelah Konsumsi Ekstrak Rumput Laut Coklat (Phaeophyta) Irene Fransiska; Didin Erma Indahyani; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 8 No 1 (2020): Volume 8 No. 1, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i1.11349

Abstract

In the case of Diabetes Mellitus, it will trigger some changes in lipid metabolism and lipoprotein composition, one of them is cholesterol. Cholesterol is a lipid that plays an important role in the structure of cell membranes. Seaweed contains bioactive components of flavonoids which reduce cholesterol levels. Brown seaweed contains bioactive components of alkaloids, flavonoids, triterpenoids, saponins, phenol hydroquinone, tannins, chlorophyll and β-carotene pigments. The bioactive component of brown seaweed also has strong antioxidant activity that can prevent damage caused by oxidative stress on pancreatic β cell function and acts as a trap for various free radicals and can reduce diabetic rat lipid peroxidation. This study to analyze the effect of giving brown seaweed extract on cholesterol levels in diabetic mice.This study was divided into 4 sample groups, namely the normal group, negative controls (diabetic mice), positive controls (diabetic mice + 1.3 mg / 20 gr BB metformin), K1 (diabetic mice + brown seaweed extract). The seaweed dose of 10mg / 20grBB is given on a daily basis for 21 days. Checking blood cholesterol levels in serum using the POD CHOD method and measured using biolysers. Diabetic mice with brown seaweed extract were significantly (p <0.05) lower cholesterol level of 68.94 mg / dL than diabetic mice 81.75 mg / dL. It was concluded that brown seaweed extract had an effect on reducing total cholesterol levels in diabetic mice. Keywords : Cholesterol levels, Diabetic mice, Brown Seaweed
Co-Authors Amandia Dewi Permana Shita Chintya Monica Amelinda Debi Suntari Deskatilana, Neny Didin Erma Indahyani Dominica Diana Siswadi Dwi Prijatmoko Dyah Indartin Setyowati Dyah Setyorini Effendi, Fitria Yolanda Mellinia Filky Nanda Mafilda Irene Fransiska Kiswaluyo . Melok Aris Wahyukundari, Melok Aris Misrohmasari, Elyda Murwanenda, Rachel Pamase, Ulrico Adnan Prihatiningrum, Berlian Rani Maharani Ratih Iswari Ningtias Rendra Chriestedy Prasetya Roedy Budirahardjo Safitri, Rahmidian Sulistiyani Surartono Dwiatmoko Tecky Indriana Yona Anindita Zahara Meilawaty Zahreni Hamzah