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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) JURNAL PHARMASCIENCE Safari : Jurnal Pengabdian Masyarakat Indonesia
Nurlely Nurlely
Jurusan Teknik Sipil, Fakultas Teknik, Universitas Syiah Kuala
Arts Humanities Chemistry Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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PREVALENSI, KARAKTERISTIK PASIEN, DAN PROFIL TERAPI HIPERTENSI PADA PASIEN PENYAKIT GINJAL KRONIK STADIUM AKHIR DI RSUD RATU ZALECHA, MARTAPURA, KALIMANTAN SELATAN Srikartika, Valentina Meta; Intannia, Difa; Nurlely, Nurlely
JURNAL PHARMASCIENCE Vol 1, No 1 (2014): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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INTISARIHipertensi merupakan komplikasi yang paling sering terjadi pada pasien dengan penyakit ginjal kronis (PGK). Hipertensi yang tidak terkontrol dapat menyebabkan keparahan kondisi ginjal dari pasien PGK itu sendiri. Penelitian ini bertujuan untuk mengetahui prevalensi, karakteristik pasien dan profil terapi hipertensi pada pasien PGK stadium akhir di RSUD Ratu Zalecha, Martapura, Kalimantan Selatan. Penelitian ini merupakan penelitian deskriptif dengan metode pengumpulan data retrospektif melalui rekam medik pasien rawat jalan yang menjalani hemodialisis. Data yang didapat dianalisis menggunakan statistika deskriptif (Frequency dan cross-tabulation) dengan program SPSS. Hasil penelitian menunjukkan bahwa 92.16% dari 51 pasien PGK mengalami hipertensi, dimana 61.70% dari pasien hipertensi adalah perempuan, dan 63,80% berumur 41-65 tahun. Berdasarkan tingkat keparahan hipertensi, 40.63% pasien mengalami hipertensi stage-1, dan masing-masing 24.22% pasien mengalami hipertensi stage-2 dan pra-hipertensi. Terapi obat tunggal merupakan terapi yang paling banyak diberikan kepada pasien (63.30%), disusul dengan terapi kombinasi 2 obat (32.1%), kombinasi 3 obat (3.9%), dan kombinasi 4 obat (0.8%). Terapi tunggal yang paling banyak diberikan adalah Amlodipin (52.3%%), Furosemid (4.7%), dan Captopril (3.1%). Sedangkan kombinasi 2 obat dan 3 obat yang paling banyak berturut-turut adalah kombinasi Amlodipin-Captopril (28.9%), dan kombinasi Bisoprolol-Furosemid-Telmisartan (3.1%). Terdapat peresepan anti hipertensi yang menggunakan kombinasi 4 obat yaitu Amlodipin-Diltiazem-Furosemid-Valsartan sebanyak 0.8%.Kata kunci: hipertensi, penyakit ginjal kronik, profil terapiABSTRACTHypertension is the most common complication in patients with chronic kidney disease (CKD). Uncontrolled hypertension can lead to kidney condition severity of CKD patients themselves. This study aimed to determine the prevalence, patient characteristics and treatment profile of hypertension in patients with CKD stage late in Ratu Zalecha Hospital, Martapura, South Kalimantan. This study is a descriptive study with retrospective data collection methods through the medical records of patients undergoing outpatient hemodialysis. The data obtained were analyzed using descriptive statistics with SPSS. The results showed that 92.16% of the 51 patients with CKD have hypertension, where 61.70% of hypertensive patients are women, and 63.80% aged 41-65 years. Based on the severity of hypertension, 40.63% of patients had hypertension stage-1, and 24.22% respectively of patients had stage-2 hypertension and pre-hypertension. Single drug therapy is the most widely therapy given to patients (63.30%), followed by 2 drug combination therapy (32.1%), a combination of 3 drugs (3.9%), and a combination of 4 drugs (0.8%). Single therapy is the most widely prescribed amlodipine (52.3 %%), furosemide (4.7%), and captopril (3.1%). While the combination of 2 drugs and the drug most widely 3 in a row is a combination of amlodipine-Captopril (28.9%), and the combination of Bisoprolol-Furosemide-Telmisartan (3.1%). There prescribing the use of antihypertensive medication is a combination of 4-Diltiazem-furosemide amlodipine-valsartan as much as 0.8%.Keywords: hypertension, chronic kidney disease, therapeutic profile
Pengujian Daya Cerna Protein Ikan Haruan (Channa striata) Asal Kota Banjarmasin Nurlely, Nurlely; Muslimah, Muslimah; Triyasmono, Liling
JURNAL PHARMASCIENCE Vol 1, No 2 (2014): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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Abstrak            Ikan haruan banyak dimanfaatkan oleh masyarakat kota Banjarmasin untuk membantu proses penyembuhan luka karena mengandung protein yang tinggi. Tujuan penelitian ini adalah menentukan kadar protein tercerna secara in vitro daging ikan haruan asal kota Banjarmasin. Ikan haruan yang digunakan memiliki berat 250-400 g dengan panjang 25-38 cm. Serbuk daging ikan dibuat dengan pengeringan 40ºC. Hasil uji pendahuluan protein dengan metode millon dan xantoprotein dari serbuk daging ikan haruan menunjukkan hasil positif. Hasil analisis protein tercerna dari uji daya cerna protein secara in vitro adalah 98,486±0,1031% dengan %RSD 0,1047%. Oleh karena itu dapat disimpulkan bahwa ikan haruan asal kota Banjarmasin memiliki daya cerna protein yang tinggi.Kata kunci: Ikan haruan (Channa striata),  daya cerna protein  AbstractSnakehead fish is so much used by the people in Banjarmasin in order to help the healing process due to possessing high protein content. The purpose of this study was to determine the digestible protein content by in vitro analysis in snakehead fish from Banjarmasin. Snakehead fish samples weighing 250-400 g with a length of 25-38 cm. Fillet powder was dried at 40ºC. Preliminary test results of protein from fillet powder using Millon and xantoprotein methods showed positive results. The result of the in vitro protein digestibility was 98.486±0.1031% with %RSD of 0.1047%. Therefore, it can be concluded that snakehead fish from Banjarmasin possesses high protein digestibility.Keywords: Snakehead fish (Channa striata), protein digestibility.
Kajian Potensi Interaksi Obat Antihipertensi Pada Pasien Penderita Gagal Ginjal Kronik Stadium V Di Ruang Rawat Inap Penyakit Dalam RSUD Ulin Banjarmasin Periode Januari 2013 – Juni 2014 Fiqrianty, Amelia; Srikartika, Valentina Meta; Nurlely, Nurlely
JURNAL PHARMASCIENCE Vol 1, No 2 (2014): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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Abstrak            Penggunaan antihipertensi dengan obat lain pada pasien GGK dapat menimbulkan terjadinya potensi interaksi obat. Tujuan dari penelitian ini adalah untuk menghitung potensi interaksi obat  antihipertensi  pada  pasien  GGK stadium V di RSUD Ulin Banjarmasin Periode  Januari  2013  –  Juni  2014. Potensi interaksi obat yang ditemukan menurut software online, diperoleh 390 kasus berpotensi interaksi obat, yaitu: 180 (27,7 %) minor, 270 (69,2%) moderate dan 12 (3,1 %) major. Menurut Drug Interaction Facts: The authority on drug interaction, diperoleh 112 kasus berpotensi interaksi obat, yaitu : signifikansi 1 sebanyak 8 (7,1%) , signifikansi 2 sebanyak 13 (11.6%), signifikansi 3 sebanyak 70 (62,5 %), signifikansi 4 sebanyak 1 (0,9%) dan signifikansi 5 sebanyak 20 (17,9%). Oleh karena itu perlu dilakukan monitoring terhadap pasien dan komunikasi antara farmasis dan tenaga kesehatan lain dalam menentukan terapi untuk mencegah atau menghindari terjadinya interaksi obat. Kata kunci : Interaksi Obat, Antihipertensi, Gagal Ginjal Kronik. Abstract The use of antihypertensive drugs, alone and with combination, among patients with Cronic Kidney Disease can lead to potential drug interactions. The purpose of this research is to determine the potential interactions of antihypertensive drugs in five grade chronic kidney disease patients of RSUD Ulin Banjarmasin period January 2013-June 2014. According to the online software, it is found that 390 in cases of potential drug interactions, there are 180 cases (27,7%) of minor interactions, there are 270 cases (69,2%) of moderate interactions, there are 12 cases (3,1%) of major interactions. According to the Drug Interaction Facts: The authority on drug interactions (Tatro, 2008), it is obtained that in 112 cases of potential drug interactions, there are 8 cases (7,1%) of significance 1; 13 cases (11,6%) of significance 2; 70 cases (62,5%) of significance 3; 1 cases (0,9%) of significance 4 and 20 cases (17,9%) of significance 5. Hence, the patients need to be monitored and communications among pharmacists and health professionals need to be done in deciding appropriate treatment to avoid drug interactions.Keywords : drug interactions, antihypertensive drug, chronic kidney disease
Pemanfaatan Abu Sawit Dalam Produksi Telur Asin Samsul Hadi; Setiawan, Deni; Nurlely, Nurlely; Kamelia, Suci; Putri, Lusiana Ernadi; Salma, Salma; Irawati, Irawati; Jannah, Raudatul
SAFARI :Jurnal Pengabdian Masyarakat Indonesia Vol. 3 No. 4 (2023): Oktober: Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/safari.v3i4.829

Abstract

Salted eggs are one of the most popular egg processing products in South Kalimantan. The purpose of making salted eggs is to remove the fishy taste and increase the shelf life of eggs. UKM Salted Egg 'Gold' Martapura is one of the salted egg producers in the region. Even though UKM 'Gold' Martapura Salted Egg already has a P-IRT permit, the permit has expired. Some of the problems faced by these SMEs include high ash prices, volatility in the base price of eggs, the lack of quality assurance for salted egg production, and product marketing management that is not yet optimal. The proposed solution is to increase sales profits by reducing production costs and improving the quality of the final product. In addition, it is necessary to increase insight into product innovation and the use of promotional media such as attractive label designs and unique marketing strategies. The results of implementing this solution show an increase in salted egg production, a decrease in production costs by utilizing palm ash which is available free of charge throughout the season, an increase in the overall quality and nutritional content of the product, and an increase in selling value through the renewal of salted egg packaging. Thus, it can be concluded that this program is very helpful for the development of the 'Golden' Salted Egg UKM business in the business they have run
UJI EFEKTIVITAS EKSTRAK AIR IKAN HARUAN (Channa striata) ASAL KALIMANTAN SELATAN TERHADAP BLEEDING TIME DAN CLOTTING TIME SECARA IN VIVO Norhalifah, Norhalifah; Rahmawanty, Dina; Nurlely, Nurlely
Media Farmasi: Jurnal Ilmu Farmasi Vol. 13 No. 2: September 2016
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v13i2.7775

Abstract

Ikan haruan memiliki kandungan albumin yang tinggi, mengandung asam amino yang dapat meningkatkan daya tahan tubuh dan membantu proses penyembuhan luka. Penelitian ini bertujuan untuk menguji efektivitas ekstrak air ikan haruan (Channa striata) terhadap bleeding time dan clotting time tikus putih jantan yang mengalami luka dan menentukan dosis ekstrak air ikan haruan yang paling efektif menurunkan bleeding time dan clotting time. Jenis penelitian yang digunakan penelitian eksperimental murni (true experimental design). Tiga puluh tikus jantan dibagi menjadi 5 kelompok. Kelompok I (kontrol negatif), kelompok II (kontrol positif), kelompok III, IV dan V  kelompok ekstrak air ikan haruan konsentrasi 10%, 20% dan 40%. Ekstrak air ikan haruan berupa ekstrak kental yang diencerkan dengan akuades, sehingga dosis ekstrak air ikan haruan dibuat dalam konsentrasi persen (%). Hewan uji diberi injeksi heparin secara sub kutan selama 5 hari, kemudian diberi sediaan uji selama 5 hari dicatat bleeding time dan clotting time tiap 2 hari sekali selama pemberian sediaan uji. Analisis data menggunakan Two Way Anova. Hasil penelitian menunjukkan persentase daya penurunan bleeding time dari semua kelompok meliputi kontrol negatif, kontrol positif, ekstrak air ikan haruan 10%, 20% dan 40% berturut-turut yaitu 48,36%; 67,36%; 72,37%; 75,21%; 82,10% dan persen daya penurunan clotting time berturut-turut yaitu 52,70%; 70,29%; 76,61%; 76,89%; dan 78,93%. Kesimpulan penelitian ini ekstrak air ikan haruan mampu menurunkan bleeding time dan clotting time pada tikus putih jantan yang mengalami luka dengan dosis efektif 40%.
Co-Authors Amelia Fiqrianty, Amelia DENI SETIAWAN Difa Intannia Dina Rahmawanty Irawati Irawati Kamelia, Suci Liling Triyasmono Muslimah Muslimah Norhalifah, Norhalifah Putri, Lusiana Ernadi raudatul jannah Salma Salma Samsul Hadi Valentina Meta Srikartika, Valentina Meta