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Dermatoglyphy in Breast Cancer Patients: A Systematic Review Rara Inggarsih; Akhyar Dyni Zakyah; Lusia Hayati; Joko Marwoto; Septi Purnamasari; Arwan Bin Laeto; Masayu Farah Diba
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 11 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i11.368

Background. Breast cancer is one of the four types of cancer among women and is the most frequently diagnosed in most countries. Breast cancer occurs due to DNA damage and genetic mutations affected by exposure to estrogen, inheritance of damaged DNA, or pro-cancer genes such as BRCA1 and BRCA2. Therefore, a family history of ovarian cancer or breast cancer increases the risk of developing breast cancer. The embryo of the breast develops around the age of 6 weeks of pregnancy. Similar to breast development, fingerprint patterns also develop during the 6-13 weeks of pregnancy. Thus, the genetic message contained in the genome occurred during that period and was reflected in the dermatoglyphic pattern.Methods. The literature search was systematically used using PubMed, Cochran, Google scholar, and other Gray literature between 2010-2020. Of the 69 publications identified, 21 met the criteria and were included in the review. The review is carried out following the provisions of PRISMA (Preferred Reporting Items for Systematic Review).Results. This systematic review showed fairly consistent findings in breast cancer patients who tended to have more whorl fingerprint patterns and larger ATD angles. For radial loops, ulnar loops and arches were minor compared to the control group potential as an initial screening tool in at-risk groups.Conclusion. Long-term and follow-up studies with larger sample sizes in various ethnicities are needed to validate dermatoglyphics in anthropometric measurements as a promising marker of breast cancer.

Dermatoglyphy in Breast Cancer Patients: A Systematic Review Rara Inggarsih; Akhyar Dyni Zakyah; Lusia Hayati; Joko Marwoto; Septi Purnamasari; Arwan Bin Laeto; Masayu Farah Diba
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 11 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i11.368

Background. Breast cancer is one of the four types of cancer among women and is the most frequently diagnosed in most countries. Breast cancer occurs due to DNA damage and genetic mutations affected by exposure to estrogen, inheritance of damaged DNA, or pro-cancer genes such as BRCA1 and BRCA2. Therefore, a family history of ovarian cancer or breast cancer increases the risk of developing breast cancer. The embryo of the breast develops around the age of 6 weeks of pregnancy. Similar to breast development, fingerprint patterns also develop during the 6-13 weeks of pregnancy. Thus, the genetic message contained in the genome occurred during that period and was reflected in the dermatoglyphic pattern.Methods. The literature search was systematically used using PubMed, Cochran, Google scholar, and other Gray literature between 2010-2020. Of the 69 publications identified, 21 met the criteria and were included in the review. The review is carried out following the provisions of PRISMA (Preferred Reporting Items for Systematic Review).Results. This systematic review showed fairly consistent findings in breast cancer patients who tended to have more whorl fingerprint patterns and larger ATD angles. For radial loops, ulnar loops and arches were minor compared to the control group potential as an initial screening tool in at-risk groups.Conclusion. Long-term and follow-up studies with larger sample sizes in various ethnicities are needed to validate dermatoglyphics in anthropometric measurements as a promising marker of breast cancer.

Basic Concept of Cell: A Narrative Review Rachmat Hidayat; Joko Marwoto; Lusia Hayati
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.167

All body functions depend on cell integrity. Therefore, understanding cell biology is intrinsically important for understanding disease. A vast amount of information reveals how the cell behaves like an organism with many social cells. At the heart of cell biology is cell communication—how messages originate and are transmitted, received, interpreted, and used by cells. This efficient communication between, and within the cell maintains the function of the cell and its specialization. Intercellular signals enable each cell to determine its position and specific role. Cells must demonstrate a "chemical preference" for other cells and the environment that surrounds them to maintain the integrity of the whole organism. When they no longer tolerate this preference, the conversation ends and the cell adapts (sometimes changes in function) or becomes vulnerable to isolation, injury, illness, or even death. This review explains the function of each component in the cell and its role in life.

Knowledge And Perceptions of Nutrition and Weight Among First-Year Medical Students at Sriwijaya University Mitha Ramadea; Ardesy Melizah Kurniati; Joko Marwoto; Syarif Husin; Wardiansyah Wardiansyah; Syarinta Adenina
Biomedical Journal of Indonesia Vol. 10 No. 3 (2024): Vol 10, No 3, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i3.202

Introduction. Medical students of Sriwijaya University batch 2019 are new students who don’t have much knowledge about nutrition. In addition, new students also don’t know how to calculate Body Mass Index (BMI) through body height and weight. This study aimed to know the level of nutritional knowledge and the suitability of weight perception among the medical students of Sriwijaya University batch 2019. Methods. Descriptive research with a cross-sectional research design was conducted in Health Clinic UPT of Sriwijaya University and the Faculty of Medicine of Sriwijaya University in September 2019. The sample of this study was all medical students from Sriwijaya University batch 2019 who met the inclusion and exclusion criteria. The data was obtained through direct measurement and filling M-GNKQ questionnaire and weight perception questionnaire online. Results. In this study, 222 students met the inclusion and exclusion criteria, with 74 male students and 148 female students. As many as 70.7% of students have normal nutritional status. The average value of nutrition knowledge is 18.21 (45.5%) with the lowest value 0 and the highest value 32. Of all of the students, only 52.3% can perceive body weight correctly. The rest, as much as 33.3% is exaggerating perception and 14.4% is reducing perception. Conclusion. The knowledge of nutrition among the medical students of Sriwijaya University batch 2019 is still quite low and there are still many students who mistakenly perceive their weight.

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