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All Journal Jurnal Penelitian Saintek Jurnal Bahan Alam Terbarukan Lantanida Journal Jurnal Kreativitas PKM ALKIMIA : Jurnal Ilmu Kimia dan Terapan Indonesian Journal of Halal Research Indonesian Journal of Community Empowerment Jurnal Teknologi Lingkungan InSTEM Catalyx : Journal of Process Chemistry and Technology
Astri Senania, Astri
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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The Opportunities of Using Malay Apple (Syzygium malaccense (L). Merr. & Perry) Wood Stem Extract as Halal and Thayyib Antidiabetic Drugs Fauziah, Nenden; Senania, Astri; Nuari, Dhoni Anshar; Setianingrum, Marginingsih
Indonesian Journal of Halal Research Vol. 1 No. 2 (2019): August
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ijhar.v1i2.5328

Abstract

The use of existing antidiabetic drugs generally causes dangerous side effects, while the use of insulin has a problem with the halal status of the ingredients. Treatment with halal and thayyib medicinal ingredients is needed by Muslims, so it is necessary to find antidiabetic drugs that are halal and thayyib. The use of natural materials such as malay apple can be a solution for halal medicine. The study on antihyperglycemic activity of extracts of malay apple stem wood have been done. Invivo studies were carried out on animal experiments in male swiss webster mice using the glucose tolerance method. The experimental results showed a decrease in blood glucose levels after feeding with extract of malay apple stem wood at doses of 100 mg/Kgbw, 200 mg/Kgbw and 400 mg/Kgbw, which were significantly different compared to the control group (p <0.05), but effective doses shown at a dose of 100 mg/Kgbw. Measurement of moisture and ash content, levels of heavy metal and microbial contamination, showed that the simplicia of malay apple stem wood is safe. The results of this study indicate that malay apple wood extract is a material that is very likely to be used as antidiabetic drugs that are halal and thayyib.
Precision Surface Engineering of Functionalized Nanoparticles for Enhanced Catalytic Activity and Stability Astri Senania; Ika Fitri Ulfindrayani
Catalyx : Journal of Process Chemistry and Technology Vol. 2 No. 1 (2025): January 2025
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/catalyx.v2i1.1269

Abstract

Nanoparticles (NPs) offer exceptional catalytic potential due to their high surface-area-to-volume ratios and tunable surface chemistries. However, limitations such as agglomeration, leaching, and poor selectivity hinder their broader application. This study investigates the role of surface functionalization in enhancing catalytic performance metrics, including activity, selectivity, and durability, across noble metal and metal oxide nanoparticles. Functionalized nanoparticles were synthesized via chemical reduction, sol–gel, and electrochemical methods, followed by ligand exchange, polymer grafting, and core–shell fabrication. Characterization tools TEM, XPS, TGA, and ICP-OES were employed to link surface features with performance. Catalytic activity was tested across model reactions, and key metrics such as turnover frequency (TOF), conversion efficiency, selectivity, and cycle stability were quantified. Results demonstrate that multidentate ligands, polymer brushes, and Janus morphologies significantly improve catalytic outcomes. AuNPs functionalized with tripodal phosphines achieved TOFs up to 2100 h⁻¹, while PdNPs with polymer brushes retained over 90% activity after 10 cycles. Correlation analyses confirmed that optimal ligand coverage (4.7–6.2 mg/m²) reduces activation energy and enhances electron transfer. Structural and electronic stability were validated through TEM and XPS, and real-time spectroscopic data supported mechanistic interpretations. The study concludes that surface functionalization is a powerful strategy for engineering high-performance catalysts. It offers a design framework for linking structural features to functional outcomes, paving the way for intelligent, adaptive catalytic systems.
Co-Authors Achmad Syamsudin Agus Prasetya Alawiyah, Aika Latifah Anggun Sucia Saputri Annisa Rahmasari Kanto, Dhini Apriani, Riza ASMAN SADINO, ASMAN ATTI SHOLIHAH Dhoni Anshar Nuari Fachry Abda El Rahman Fauziah, Nenden FITRI DARA Handayani, Niknik Hary Sulistyo Ika Fitri Ulfindrayani Intan Permatasari Kanto, Dhini Annisa Rahmasari Luthfiyah, Ai Fifih Marginingsih Setianingrum Maulidanti, Nadiyya Nur Muchlis Muchlis Muharram, Rahma Mekar Mustika Muzdalipah Naima, Shafira Salsa Nenden Fauziah Nina Karnia Novi Yanti Nuari, Dhoni Anshar Nurdin, Abdul Malik Ramadani, Jasmine Aura Randi Rahadian Riska Prasetiawati, Riska SAMBAS SAMBAS Setianingrum, Marginingsih Sumiarti, Imas WIDYARANI WIDYARANI Yuningsih, Isma Aulia