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HYPNOTIC-SEDATIVE ACTIVITY TEST OF 70% ETHANOL EXTRACT OF LETTUCE (Lactuca sativa L.) IN MALE WHITE MICE SWISS WEBSTER STRAIN Sadino, Asman; Renggana, Hesti; Suwendar, Suwendar; Apriani, Riza; Nurhandayani, Yuni
Jurnal Ilmiah Farmako Bahari Vol 15, No 2 (2024): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v15i2.3090

Humans who use medicines for insomnia may experience a variety of adverse effects, including dependence. Traditional medicine frequently uses lettuce (Lactuca sativa L.) to treat various conditions, including sleep difficulties. Terpenoids, which are secondary metabolites found in lettuce plants, are to blame for this. This study aimed to see if an ethanolic extract of lettuce leaf had any sedative-hypnotic activity in Swiss Webster strain male white mice induced by phenobarbital at a dose of 90 mg/KgBB intraperitoneally. In this study, the post-test-only control strategy was employed. The animals were divided into six groups (n = 4): negative (aqua dest), positive (Na-CMC 0.5%), comparison (diazepam 1.3 mg/KgBB), and ethanolic extract of lettuce leaf at doses of 300 mg/KgBB, 400 mg/KgBB, and 500 mg/KgBB. The parameters observed in this study were a combination of parameters from previous studies, namely the number of falls, sleep onset, and sleep duration in mice. The data obtained were then processed statistically using the one-way ANOVA (analysis of variance) and post-hoc test follow-up analysis with the LSD (least significant difference) test. The results showed that the ethanolic extract of lettuce leaves at 300, 400, and 500 mg/KgBB had a sedative-hypnotic effect. Doses of 300 mg/KgBB only increased sleep duration. In contrast, 400 and 500 mg/KgBB increased the number of falls, rapid sleep onset, and increased sleep duration, significantly different from positive controls (p<0.05). The effective dose of ethanolic extract of lettuce leaf as a sedative-hypnotic was 400 mg/KgBB.

Counseling on the Dangers of Repeated Use of Cooking Oil and Training on the Valorization of Used Cooking Oil for Dorokdok Cracker Producer in Suci Village Fauziah, Nenden; Prasetiawati, Riska; Senania, Astri; Apriani, Riza; Annisa Rahmasari Kanto, Dhini
Jurnal Inovasi Sains dan Teknologi untuk Masyarakat Vol. 2 No. 2 (2024): November
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember. Jl. Kalimantan No.37, Krajan Timur, Jemberlor, Kec. Sumbersari, Jember Regency, East Java 68121

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v2i2.1574

Producers of cowhide crackers (dorokdok) in Suci Village have the potential to produce cooking oil waste of more than 1 ton/week. In addition, cooking oil is often used repeatedly to reduce production costs. From situation analysis and field observations, the people of Suci Village do not yet know the dangers of using used cooking oil repeatedly and how to process used cooking oil into biodiesel. This service activity aims to educate the public about the dangers of repeated use of used cooking oil and the valorization of used cooking oil into biodiesel. It is hoped that the step of valorizing used cooking oil can prevent repeated use of cooking oil without having an impact on increasing dorokdok production costs. The method of implementing service is counselling and training. Changes in community knowledge are evaluated through the implementation of pretests and posttests. The evaluation results show an increase in public knowledge about the dangers of repeated use of cooking oil and steps to valorize used cooking oil reaching 66.20%. It is hoped that the step to valorize used cooking oil will be a way to create a healthy environment and food as well as realize economic independence in Suci Village.

HYPNOTIC-SEDATIVE ACTIVITY TEST OF 70% ETHANOL EXTRACT OF LETTUCE (Lactuca sativa L.) IN MALE WHITE MICE SWISS WEBSTER STRAIN Sadino, Asman; Renggana, Hesti; Suwendar, Suwendar; Apriani, Riza; Nurhandayani, Yuni
Jurnal Ilmiah Farmako Bahari Vol 15 No 2 (2024): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v15i2.3090

Humans who use medicines for insomnia may experience a variety of adverse effects, including dependence. Traditional medicine frequently uses lettuce (Lactuca sativa L.) to treat various conditions, including sleep difficulties. Terpenoids, which are secondary metabolites found in lettuce plants, are to blame for this. This study aimed to see if an ethanolic extract of lettuce leaf had any sedative-hypnotic activity in Swiss Webster strain male white mice induced by phenobarbital at a dose of 90 mg/KgBB intraperitoneally. In this study, the post-test-only control strategy was employed. The animals were divided into six groups (n = 4): negative (aqua dest), positive (Na-CMC 0.5%), comparison (diazepam 1.3 mg/KgBB), and ethanolic extract of lettuce leaf at doses of 300 mg/KgBB, 400 mg/KgBB, and 500 mg/KgBB. The parameters observed in this study were a combination of parameters from previous studies, namely the number of falls, sleep onset, and sleep duration in mice. The data obtained were then processed statistically using the one-way ANOVA (analysis of variance) and post-hoc test follow-up analysis with the LSD (least significant difference) test. The results showed that the ethanolic extract of lettuce leaves at 300, 400, and 500 mg/KgBB had a sedative-hypnotic effect. Doses of 300 mg/KgBB only increased sleep duration. In contrast, 400 and 500 mg/KgBB increased the number of falls, rapid sleep onset, and increased sleep duration, significantly different from positive controls (p<0.05). The effective dose of ethanolic extract of lettuce leaf as a sedative-hypnotic was 400 mg/KgBB.

Nutritional Counseling for Pregnant and Breastfeeding Mothers as an Effort to Prevent Stunting in Sekarwangi Village, Malangbong District, Garut Regencyt Apriani, Riza; Senania, Astri; Kanto, Dhini Annisa Rahmasari; Sadino, Asman
Indonesian Journal of Community Empowerment (IJCE) Vol 5 No 02 (2024): Indonesian Journal of Community Empowerment (May)
Publisher : Fakultas Kewirausahaan Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35899/ijce.v5i2.923

Stunting menjadi salah satu masalah kesehatan yang menjadi perhatian pemerintah karena berdampak pada kualitas sumber daya manusia Indonesia. Hingga saat ini, kasus terjadinya stunting di Indonesia masih tergolong tinggi. Salah satu cara yang dianggap efektif untuk mempercepat capaian zero stunting adalah dengan meningkatkan kesadaran masyarakat tentang pencegahan stunting, khususnya pada ibu hamil dan menyusui. Tujuan dari kegiatan pengabdian ini adalah untuk mendukung program pemerintah untuk mencapai zero stunting melalui peningkatan pengetahuan ibu hamil dan menyusui mengenai gizi yang baik pada 1000 Hari Pertama Kehidupan. Metode yang digunakan adalah dengan pemberian penyuluhan dan penyebaran brosur. Peserta kegiatan ini yaitu ibu hamil, ibu menyusui dan ibu PKK di lingkungan Desa Sekarwangi, Kecamatan Malangbong, Kabupaten Garut. Total peserta kegiatan ini yaitu 50 orang. Kegiatan ini dilaksanakan pada hari Sabtu, 20 Agustus 2022. Hasil kegiatan ini didapatkan bahwa terdapat peningkatan skor pengetahuan setelah diberikan penyuluhan. Berdasarkan hal tersebut dapat disimpulkan bahwa penyuluhan tentang pencegahan stunting dapat meningkatkan pengetahuan ibu hamil dan menyusui di wilayah Desa Sekarwangi, Kecamatan Malangbong, Kabupaten Garut. Adanya peningkatan pengetahuan ini diharapkan dapat mendukung pencapaian zero stunting di daerah tersebut.

Improving Elderly Knowledge on Hypertension through Health Education in Parakan Village, Garut Sadino, Asman; Lubis, Novriyanti; Suryana, Shendi; Prasetiawati, Riska; Hermawan, Belya Anindia; Cahyati, Effan; Apriani, Riza; Karina, Karina; Rena, Rena
Indonesian Journal of Community Empowerment (IJCE) Vol 6 No 2 (2025): Indonesian Journal of Community Empowerment (May)
Publisher : Fakultas Kewirausahaan Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35899/ijce.v6i2.1034

Hypertension is a non-communicable disease often referred to as a "silent killer" because it may develop without noticeable symptoms and can lead to serious complications if left untreated. Elderly individuals are among the high-risk groups who require special attention in efforts to prevent and control hypertension. This community service activity aimed to improve the knowledge of elderly residents regarding hypertension through health education as a preventive measure against further complications. The program was conducted in Parakan Village, Garut Regency, involving 30 elderly participants. The method used was health education combined with pre-test and post-test assessments to evaluate knowledge improvement. The results showed a significant increase in understanding after the session, particularly regarding the symptoms and prevention of hypertension. Another notable finding was that most participants had only elementary-level education, which influenced their receptiveness to health information. In conclusion, health education proved effective in enhancing the elderly's knowledge of hypertension and its potential complications. Periodic follow-up education and collaboration with local health services are recommended to sustain the impact.

The Environmental education and entrepreneurship-training based on dorokdok’s used cooking oil waste in Suci Village Fauziah, Nenden; Senania, Astri; Apriani, Riza; Handayani, Niknik; Yanti, Novi; Naima, Shafira Salsa; Muharram, Rahma Mekar; Yuningsih, Isma Aulia; Sumiarti, Imas; Ramadani, Jasmine Aura
Indonesian Journal of Community Empowerment (IJCE) Vol 6 No 3 (2025): Indonesian Journal of Community Empowerment (August)
Publisher : Fakultas Kewirausahaan Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35899/ijce.v6i3.1090

Used cooking oil from dorokdok frying pans, which potential to damage the environment, can become a new business opportunity. This community service program aims to raise environmental-awareness while also motivating people to become entrepreneurs by utilizing used cooking oil waste turn to aromatherapy candles. The community service method was carried out through an educational stage on how to handle used cooking oil waste to prevent environmental damage, followed by training on making aromatherapy candles. The educational results have successfully increased the participants' knowledge by 72.82%. The training results demonstrated the participants' skills in the process of making aromatherapy candles. The overall level of participant satisfaction with the community service process reached 82%. The results of this community service will be followed up with efforts to establish a joint business starting with the production of aromatherapy candles. This effort is expected to improve the economic and the environmental of Suci Village.

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