Article Per Year (5 Year)
p-Index From 2020 - 2025
1.945
P-Index
This Author published in this journals
All Journal Majalah Obat Tradisional KOVALEN: Jurnal Riset Kimia Akta Kimia Indonesia Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Sains Natural: Journal of Biology and Chemistry Jurnal Inovasi Teknik Kimia Aptekmas : Jurnal Pengabdian Kepada Masyarakat
Aloisius Masan Kopon
Universitas Katolik Widya Mandira
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 10 Documents
Search

 1 
AKTIVITAS ANTIHIPERKOLESTEROLEMIA EKSTRAK AKAR DAN BATANG KEMANGI HUTAN (Ocimum sanctum) PADA TIKUS PUTIH Aloysius M. Kopon, Yohana K. A. Mbulang, Agustine E. Amsik
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol 4, No 1 (2021)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.833 KB) | DOI: 10.35799/pmj.4.1.2021.34518

Abstract

ABSTRACTHypercholesterolemia is a high level of cholesterol in the blood ≥ 200 mg/dl. Ocimum sanctum is medical plants which have antihypercholesterolemic effects. This study aims to determine that antihypercholesterolemic activity and the best dose of roots and stems extracts of Ocimum sanctum which can provide antihypercholesterolemic effects in white rats fed a high fat diet. A total of 25 rats divided into 5 groups that is group positive control, group negative control, group roots and stems extracts of Ocimum sanctum with dose of 50 mg/kg body weight, 75 mg/kg body weight  and 100 mg/kg body weight. Cholesterol and triglyseride levels measurement using the CHOP- PAP and GPO-PAP methods. The results of statistical analysis showed that there was an antihypercholesterolemic effect from the three doses of  root and stem extracts Ocimum sanctum. The best dose as an antihypercholesterolemia  is dose III (100 mg/kg body weight). Keywords : Antihypercholesterol, total cholesterol, triglycerides. ABSTRAKHiperkolesterolemia merupakan tingginya kadar total kolesterol dalam darah ≥ 200 mg/dl. Kemangi hutan merupakan tanaman obat yang memiliki efek sebagai antihiperkolesterolemia. Penelitian ini bertujuan untuk mengetahui aktivitas antihiperkolesterolemia dan dosis yang paling baik dari ekstrak akar dan batang kemangi hutan yang dapat memberikan efek antihiperkolesterolemia pada tikus putih yang diberi pakan diet lemak tinggi. Sebanyak 25 ekor tikus dibagi 5 kelompok yaitu kelompok kontrol positif, kelompok kontrol negatif, kelompok ekstrak akar dan batang kemangi hutan dengan dosis 50 mg/kg BB, 75 mg/kg BB, dan 100 mg/kg BB. Kadar kolesterol dan trigliserida diukur menggunakan metode CHOD-PAP dan GPO-PAP. Hasil analisis statistik menunjukkan adanya efek antihiperkolesterolemia dari ketiga dosis ekstrak akar dan batang kemangi hutan. Dosis yang paling baik sebagai antihiperkolesterolemia adalah dosis III (100 mg/kg BB). Kata kunci : Antihiperkolesterolemia, kolesterol total, trigliserida.
Skrining Senyawa Metabolit Sekunder Ekstrak Metanol Biji Alpukat (Persea Americana Mill.) Asal Pulau Timor Aloisius Masan Kopon; Anselmus Boy Baunsele; Erly Grizca Boelan
Akta Kimia Indonesia Vol 5, No 1 (2020)
Publisher : LPPM, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j25493736.v5i1.6709

Abstract

Avocados (Persea americana Mill.) have many benefits for traditional medicine especially in East Nusa Tenggara. The purpose of this study was to analyze the secondary metabolite compounds contained in avocado seeds and to identify groups compounds in avocado seeds extract. The research method used was maceration of samples for 3 days and continued with phytochemical dan FT-IR test. The result showed that methanol extract of avocado seeds contains phytochemicals based on test result of secondary metabolites, the alkaloids, flavonoids, steroids, terpenoids, saponins and tannins. While the results of FT-IR analysis showed the presences of OH, CH, C=C, and C-O groups.
PENINGKATAN PEMAHAMAN TERHADAP ILMU KIMIA MELALUI KEGIATAN PRAKTIKUM KIMIA SEDERHANA DI KOTA SOE Anselmus Boy Baunsele; Maria Benedikta Tukan; Aloisius Masan Kopon; Erly Grisza Boelan; Faderina Komisia; Maria Aloisia Uron Leba; Yustina D. Lawung
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 3 No 4 (2020): APTEKMAS Volume 3 Nomor 4 2020
Publisher : Politeknik Negeri Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.053 KB) | DOI: 10.36257/apts.v3i4.2959

Abstract

This community service was carried out on two topiks, there are a simple chemical practicum and the socialization of the risk of Plastik waste in Soe City, East Nusa Tenggara Province. This activity aims to increase the people's understanding of the chemical science which is considered dangerous for the organism. The mistake in understanding of chemical concept causes the chemistry science is to difficult to study, even though chemistry has comprehensive  benefits in life, such as in agriculture for fertilizer production, in pharmacy to synthesis the medicine, for culinary to nutrient content estimated, in the livestock sector to make vaccines, in the marine sector to manage the marine product and for environment to overcome the environmental pollution due to the waste. This activity was initiated by the students and lecturers in the Chemical Education Study Program, of Widya Mandira Catholic University with the target being Junior High School students in the Soe city. Simple practicum is done using natural materials around in order to create an easy chemistry lesson. In addition to practicum activities, there are also has a socialization activities about the risk  of Plastik waste, because Plastik waste is an environment problem in the future.
EDUKASI PEMBUATAN HAND SANITIZER BAGI MASYARAKAT KELURAHAN LILIBA KOTA KUPANG Marianus Jefri Agang; Timotius Nesanto; Aloysius M. Kopon; Maria Benedikta Tukan; Anselmus Boy Baunsele; Maria Aloisia Uron Leba; Faderina Komisia; Erly Grizca Boelan; Yustina D. Lawung
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 4 No 4 (2021): APTEKMAS Volume 4 Nomor 4 2021
Publisher : Politeknik Negeri Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.379 KB) | DOI: 10.36257/apts.v4i4.3548

Abstract

The increasing of Covid-19 spread is certainly a challenge for the community in incounter of COVID-19 pandemic. The implementation of health protocols and public understanding about COVID-19 must to be improved. One form of health protocol is the hand sanitizers utillization. Hand sanitizer can be bought at by various prices. The availability of natural abundance is the basis reason for innovations to be produce the hand sanitizers. Educational activities for the hand sanitizers produce made from betel leaf and aloe vera in the Liliba sub-district, of Kupang city using the video and YouTube as well as socialization to the community aims to provide information for the community to utiliize the natural ingredients to create the hand sanitizers. This is carried out to support the implementation of health protocols. The selection of video tutorial media is because the community can be widely access. In addition the other activities socializing about the hand sanitizers produce and distributing the home made hand sanitizer products. The socialization involved the Liliba sub-district Covid-19 team. The hand sanitizers that have been produced by practical students of chemistry educational study program of Widya Mandira University are then distributed to the audience of the socialization. The hand sanitizer production brochure distributed to the public as a simple way of academics contributing ideas to help the community on COVID-19 pandemic.
EDUKASI PEMANFAATAN TANAMAN HERBAL UNTUK MENINGKATKAN IMUNITAS TUBUH PADA MASYARAKAT KELURAHAN LILIBA Ferdinandus Pantur; Aloisius Masan Kopon; Maria Benedikta Tukan; Anselmus Boy Baunsele; Faderina Komisia; Maria Aloisia Uron Leba; Yustina Lawung; Erly Grizca Boelan
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 5 No 2 (2022): APTEKMAS Volume 5 Nomor 2 2022
Publisher : Politeknik Negeri Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36257/apts.v5i2.3581

Abstract

COVID-19 merupakan penyakit yang sedanf mewabah di dunia termasuk di Indonesia. Adanya pandemic ini menyebabkan kegiatan di semua sector terganggu, sehingga upaya pencegahan penyebaran virus ini mutlah dilakukan. Tujuan kegiatan ini adalah meningkatkan pemahaman pengetahuan tentang COVID-19 dan pemanfaatan tanaman herbal sebagai ramuan untuk meningkatkan imunitas tubuh. Sasaran utama dari kegiatan ini adalah masyarakat Kelurahan Liliba Kecamatan Oebobo-Nusa Tenggara Timur, dengan metode sosialisasi dan edukasi. Tahapan pelaksanaan kegiatan berupa tahapan persiapan dan pelaksanaan. Pada tahap persiapan TIM KKN melakukan audiensi dengan pemerintah setempat dan studi literatur. Pada tahap pelaksanaan dilakukan sosialisasi mengenai COVID-19 dan potensi tanaman herbal untuk meningkatkan imunitas tubuh serta cara pembuatannya. Hasil dari kegiatan ini dapat adalah masyarakat mendapatkan pengetahuan tambahan tentang COVID-19 serta potensi tanaman herbal yang ada disekitar dalam meningkatkan imunitas tubuh.
Aplication of Turmeric Rhizome Pigmen as Acid-Base Titration Indicator Maria Aloisia Uron Leba; Aloisius Masan Kopon; Yustina Dwisofiani Lawung; Anjelina Derci Jenimat; Faderina Komisia; Maria Benedikta Tukan; Erly Grizca Boelan; Anselmus Boy Baunsele
JURNAL SAINS NATURAL Vol. 12 No. 4 (2022): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31938/jsn.v12i4.431

Abstract

Turmeric rhizome is a source of natural yellow pigment which can be applied as a pH indicator. This pigment was extracted from turmeric rhizomes using ethanol as a solvent. The purpose of this study was to examine the application of turmeric rhizome pigment extract (TRPE) as an indicator to determine the concentration of H+, the precision and accuracy of the use of TRPE as an indicator of acid base titration. As a comparison, in this study used also a standard indicator, such as phenolphthalein (PP) and methyl red (MR). Titration was carried out on samples without spike and spike samples. The result showed that the rendement of TRPE was 35.72%. The concentration of H+ on the sample without spikes in the titration of strong acid-strong base (SASB) and strong acid-weak base (SAWB) using TRPE, PP and MR indicators gave the same result, namely 0.041 M. The concentration of H+ on spike samples in SASB and SAWB titrations using TRPE, PP and MM indicators gave the same result, namely 0.165 M. The use of TRPE in the titration of SASB, SAWB, weak acid-strong base (WASB) and weak acid-weak base (WAWB) provided good precision with the coefficient of variation (CV) obtained in the titration of samples without spikes and titrations of spike samples, respectively are 1.2% and 0.35%, but only give good accuracy in SASB and SAWB titration with the recovery in the range of 102.3%-102.7%.Keywords: accuracy; acid base; precision; titration; turmeric ABSTRAKAplikasi Pigmen Rimpang Kunyit Sebagai Indikator Titrasi Asam-BasaRimpang kunyit merupakan salah satu sumber pigmen kuning alami yang dapat diaplikasikan sebagai indikator pH. Pigmen ini diperoleh dengan cara mengekstraksinya dari rimpang kunyit menggunakan pelarut etanol. Penelitian ini bertujuan untuk  mengkaji aplikasi ekstrak pigmen rimpang kunyit (EPRK) sebagai indikator untuk menentukan konsentrasi H+ dalam sampel, presisi dan akurasi dari penggunaan EPRK sebagai indikator titrasi asam basa. Sebagai pembanding maka dalam penelitian ini digunakan pula indikator standar yakni fenolftalin (PP) dan metil merah (MM). Titrasi dilakukan terhadap sampel tanpa spike dan sampel spike. Berdasarkan hasil penelitian diperoleh rendemen EPRK sebanyak 35,72%. Konsentrasi H+ dalam sampel  tanpa spike pada titrasi asam kuat-basa kuat (AKBK) dan asam kuat-basa lemah (AKBL)  menggunakan indikator EPRK, PP dan MM memberikan hasil yang sama yaitu 0,041 M.  Konsentrasi H+ dalam sampel  spike pada titrasi AKBK dan AKBL menggunakan indikator EPRK, PP dan MM memberikan hasil yang sama yaitu 0,165 M.  Penggunaan EPRK dalam titrasi AKBK, AKBL, asam lemah-basa kuat (ALBK) dan asam lemah-basa lemah (ALBL) memberikan presisi yang baik dengan coefficient of variation (CV) yang diperoleh  pada titrasi sampel tanpa spike dan titrasi sampel spike berturut-turut adalah ˂ 1,2%  dan  ˂ 0,35%, tetapi hanya memberikan akurasi yang baik pada titrasi AKBK dan AKBL dengan recovery yang diperoleh adalah pada kisaran 102,3%-102,7%.Kata Kunci: akurasi; asam basa; presisi; titrasi; kunyit
The Effect of Ethanolic Extract of Pandanus tectorius Leaves on Spatial Memory Ability and GCMS Analysis of Potentially Therapeutic Compounds Yohana Krisostoma Anduk Mbulang; Magi Melia Tanggu Rame; Cahyani Purnasari; Aloisius Masan Kopong
Majalah Obat Tradisional Vol 28, No 1 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.79828

Abstract

Free radicals are known to damage the hippocampus and will decrease spatial memory. This condition will decrease cognitive function. This study focused on discovering the ability of the ethanolic extract of Pandanus tectorius leaves (EEPTL) to increase spatial memory and its active compounds using GC-MS. This study used twenty-five male mice (Mus musculus) divided into five groups. Three groups were given EEPTL orally using 100, 200, and 300mg/kg BW doses; one negative control (ethanol 10%) and one positive control (donepezil 0.65mg/kg BW). Each group was induced using ethanol 10% for three weeks (0.5mL/day) and tested for spatial memory using the Y-maze method. The result showed that EEPTL significantly increases mice's spatial memory ability (P<0.005). The most effective EEPTL dose is 300 mg/kg BW. GC-MS results showed that some active compounds in EEPTL are palmitic acid, stearic acid, coumarin, and 3-benzoyl-4-phenyl-ethyl linoleic. These results indicate that EEPTL increases spatial memory and contain several fatty acids, volatile oil, and phenols.
Penggunaan Sabut Kelapa Teraktivasi NaOH sebagai Adsorben Metilen Biru: Utilization of Coconut Fiber NaOH-Activated as Blue Methylene Adsorbent Anselmus Boy Baunsele; Erly Grizca Boelan; Aloisius Masan Kopon; Maximus M. Taek; Gerardus D. Tukan; Hildegardis Missa
KOVALEN: Jurnal Riset Kimia Vol. 9 No. 1 (2023): April Edition
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2023.v9.i1.16274

Abstract

Methylene blue is a textile dye with carcinogenic and mutagenic properties which can cause various problems for the environment and organisms, therefore it is necessary to treat the waste. This study describes the adsorption of methylene blue using base-activated coconut coir. Coconut coir as waste was prepared into 80 mesh-sized powder and then activated using NaOH solution. The base-activated coconut fiber was then used for methylene blue adsorption under several optimization conditions such as pH, contact time, concentration, and adsorption isotherm. The determination of methylene blue was adsorbed by the adsorbent measured using UV-VIS. The pH and contact time results were 7 and 75 minutes, respectively, with the adsorption capacity (qe) of 1.98 mg g-1 and 99.91%. The isotherm adsorption of blue methylene followed the Langmuir isotherm model with the maximum adsorption capacity (Qmax) of 0.2 mg -1. The result showed that the coconut fiber base activated could be used as a dye adsorbent.
STUDI ADSORPSI METILEN BIRU MEMANFAATKAN SABUT BUAH LONTAR Theresia Enjelina Banamtuan; Anselmus Boy Baunsele; Aloisius M. Kopon
Jurnal Inovasi Teknik Kimia Vol 8, No 2 (2023)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v8i2.8065

Abstract

Penelitian ini bertujuan untuk memanfaatkan limbah sabut buah lontar/siwalan untuk dijadikan adsorben zat warna merilan biru. Sabut buah lontar dipreparasi dengan ukuran 80 mesh kemudian dilakukan optimasi uji penyerapan metilen biru. Melalui proses adsorpsi, filtrat diuji untuk mengetahui konsentrasi filtrat menggunakan spektrofotometer UV-Vis. Berdasarkan hasil penelitian, adsorpsi maksimal terjadi pada pH 7dengan kapasitas adsorpsi (qe) adalah 1,3 mg g-1, sedangkan waktu kontak optimum adalah 50 menit dengan persentasi adsorpsi sebesar 99,4%. Karakterisasi biosorben menggunakan FTIR menunjukkan bahwa terdapat gugus aktif OH, CH, C=C dan CO dengan serapan pada bilangan gelombang secaa berturut-turut yaitu 3232,7; 2933,73; 1593,2; dan 1033,85 cm-.1 Model kinetika adsorpsi mengikuti model pseudo orde dua dengan nilai R2=1 dan model isotermal adsorpsi mengikuti model isotermal Temkin dengan nilai R2= 0,894. Hasil penelitian ini menunjukkan bahwa limbah sabut buah lontar dapat dijadikan sebagai adsorben untuk metilen biru.
KINETIKA ADSORPSI METILEN BIRU MEMANFAATKAN SERBUK GERGAJI KAYU JATI TERAKTIVASI ASAM SULFAT Anselmus Boy Baunsele; Erly Grizca Boelan; Aloisius Masan Kopon; Maria Aloisia Uron Leba; Hildegardis Missa; Rahayu Rahayu; Merpiseldin Nitsae; Dwi Siswanta
Jurnal Inovasi Teknik Kimia Vol 9, No 4 (2024)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v9i4.12024

Abstract

Peningkatan kapasitas industri memberikan dampak positif bagi masyarakat namun meninggalkan jejak kerusakan bagi lingkungan. Tujuan penelitian ini untuk membantu menangani limbah metilen biru yang sering menjadi bahan buangan dari aktivitas industri. Metilen biru menjadi salah satu masalah karena mencemari lingkungan. Berbagai penyakit misalnya kanker maupun perubahan genetik bisa terjadi karena bioakumulasi bahan ini. Penanganan masalah pencemaran lingkungan akibat metilen biru telah banyak dilakukan misalnya adsorpsi, karena metode ini cukup sederhana dan mudah diterapkan. Berbagai bahan alam digunakan sebagai adsorben, contohnya serbuk gergaji kayu jati yang dijadikan sebagai adsorben. Serbuk gergaji kayu jati pada penelitian ini diaktivasi menggunakan larutan asam sulfat. Selanjutnya dilakukan karakterisasi menggunakan FTIR, SEM-EDX dan pHpzc. Setelah dikarakterisasi lalu dilakukan analisis adsorpsi metilen biru secara batch. Variabel penelitian yaitu variasi pH dan waktu kontak. Hasil penelitian menunjukkan bahwa adsorpsi maksimal pada pH 6 dengan kapasitas adsorpsi 1,96 mg g-1 (99,3%) dan waktu kontak maksimum yaitu 30 menit dengan nilai Qe adalah 1,97 mg g-1 (99,7%)
Co-Authors Anjelina Derci Jenimat Anselmus Boy Baunsele Cahyani Purnasari Dwi Siswanta Erly Grizca Boelan Faderina Komisia Ferdinandus Pantur Gerardus Diri Tukan Hildegardis Missa Magi Melia Tanggu Rame Maria Aloisia Uron Leba Maria Benedikta Tukan Marianus Jefri Agang Maximus M Taek Merpiseldin Nitsae Rahayu Rahayu Theresia Enjelina Banamtuan Timotius Nesanto Yohana Krisostoma Anduk Mbulang Yustina Dwisofiani Lawung