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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Surya Masyarakat Jurnal Farmasi Indonesia JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Surya Masyarakat Prosiding Seminar Nasional Program Pengabdian Masyarakat Borneo Journal of Pharmacy
Dyani Primasari Sukamdi
Universitas Muhammadiyah Yogyakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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PENINGKATAN KEMAMPUAN ANTIOKSIDAN PADA KRIM KULIT JERUK NIPIS (Citrus aurantifolia S) MENGGUNAKAN VCO DENGAN METODE DPPH Dyani Primasari Sukamdi; Sabtanti Harimurti; Kunniya Amany; Vella Lailli Damarwati
JCPS (Journal of Current Pharmaceutical Sciences) Vol 7 No 2 (2024): March 2024
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Lime peel (Citrus aurantifolia S.) is rich in flavonoids, tannins, and coumarins so that it can act as an antioxidant. It can be formulated with Virgin Coconut Oil (VCO) into a cream to protect the skin and prevent aging. This study aims to determine the antioxidant activity of cream preparations containing lime peel extract with DPPH method and to determine whether the concentration of VCO can affect the physical evaluation and antioxidant activity of cream preparations. Lime peel was extracted by maceration method using 96% ethanol and cream were made using various VCO concentrations (30%, 35% and 40%). The three formulas were physically tested to determine the effect of adding VCO concentration to the physical quality of the cream. Data analysis was carried out using the One-Way Anova method and the results of the adhesive power test, dispersion and pH concluded that the significance was, therefore the addition of VCO concentration does not affect the value on adhesion, spread ability and pH. The IC50 results obtained for formulas I, II and III are 31.78 ppm, respectively; 29.64 ppm ; 26.95 ppm. Data was statistically tested using One-Way Anova, the results showed that lime peel extract cream with the addition of VCO affected antioxidant activity in cream preparations. Where the greater the concentration of VCO used in lime peel cream, the greater the antioxidant activity. Keywords : Lime peel, cream, extract, VCO, antioxidants
Enhanced Antioxidant Gel Formulation with Papaya Leaf Extract and Virgin Coconut Oil: Optimization Approach Dyani Primasari Sukamdi; Sophia Farra Ileina; Rima Erviana; Vella Lailli Damarwati; Sabtanti Harimurti; Azura Amid
Borneo Journal of Pharmacy Vol. 9 No. 2 (2026): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v9i2.9317

Abstract

Redness, pigmentation, premature aging, xerosis, and even the risk of cancer can result from excessive exposure to free radicals in the form of ultraviolet (UV) radiation, which can cause skin damage. Antioxidants, including β-carotene, α-tocopherol, ascorbic acid, and flavonoids, are present in papaya (Carica papaya) leaves and Virgin Coconut Oil (VCO). Therefore, these two components may mitigate skin imperfections caused by premature aging. This study aims to formulate and determine the antioxidant activity contained in C. papaya leaf extract gel and VCO. A laboratory-based experimental approach was implemented in this study. Using the infusion method, C. papaya leaves were extracted for 15 minutes to initiate the gel formation. The C. papaya leaf extract gel with VCO was divided into five formulations, with varying amounts of each ingredient. Organoleptic, homogeneity, viscosity, pH, spreadability, and antioxidant activity tests, conducted using the DPPH method, are included in the preparation testing process. The antioxidant activity test of C. papaya leaf extract gel with VCO in each formula yielded 91.32 ppm, 121.21 ppm, 80.19 ppm, 67.04 ppm, and 55.31 ppm. The results indicated that the quality of the gel preparation and the IC50 value of the C. papaya leaf extract gel were influenced by variations in VCO concentration.
Co-Authors Andy Eko Wibowo Annisa Krisridwany Azura Amid Inayati Murwani Rahayu Inayati Murwani Rahayu Indriastuti Cahyaningsih, Indriastuti Ingenida Hadning Krisridwany, Annisa Kunniya Amany Lutfan Lazuardi Mega Octavia Miftah Rizkia Tatra Muhammad Fariez Kurniawan Muhammad Fariez Kurniawan Muhammad Thesa Ghozali Octavia, Mega Pinasti Utami, Pinasti Pramitha Esha Nirmala Dewi Pramitha Esha Nirmala Dewi Radhwa Fauztina Rahajeng, Bangunawati Rima Erviana Sabtanti Harimurti Sabtanti Harimurti Sophia Farra Ileina Sumarni Sumarni Syagata, Anindhita Syahbi Tyas Fabandari Dewi Hapsari Vella Laili Damarwati Vella Lailli Damarwati