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Taralan Tambunan
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Probiotic treatment in children with lactose intolerance – An open labeled the one group pre-test post-test experimental study Zainul Arifin; Aswitha D. Boediarso; Taralan Tambunan
Paediatrica Indonesiana Vol 46 No 3 (2006): May 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.3.2006.139-43

Abstract

Background Lactose intolerance is the most common disorder ofintestinal carbohydrate digestion. Probiotic that contains the cor-rect strain in appropriate amount can be used as an alternativedietary for lactose intolerance patients.Objective This study was designed to describe the role of probioticin relieving lactose intolerance symptoms in children consumedfull-cream milk.Methods This study was a clinical trial. Inclusion criteria was chil-dren aged 12-14 years old, had a good nutrition and health status,with positive breath hydrogen test (BHT) result and lactose intoler-ance symptom(s), and their parents gave consent. Forty-two chil-dren were included. All subjects consumed one glass (200 ml) offull-cream milk twice a day for 21 days and recorded intolerancesymptoms. Probiotic was added from 8 th to 21 st day in their milk,and responses of treatment were evaluated by scoring system(based on borborigmic, flatulence, abdominal bloating, nausea andvomiting, abdominal pain, and diarrhea symptoms). At the end ofstudy they were undergone second BHT examination.Results There were decreasing mean score rates at 7 th day (pre)13.8 (SD 5.5) compared with 7.5 (SD 3.5) at 14 th day (after) andwas statistically significant (P<0.001). Mean score rate at 7 th day(pre) 13.8 (SD 5.5) compared with 21 st day (after) was 0.119 (SD0.55) and was statistically significant (P<0.001). At the end of study,only 2 subjects showed clinical signs of lactose intolerance. Thirty-six subjects had normal BHT result at 21 st day and was statisti-cally significant (P<0.001).Conclusion Two weeks administration of probiotic could relievelactose intolerance symptoms in children consumed full-cream milk
Neonatal seizures: clinical manifestations and etiology Daisy Widiastuti; Irawan Mangunatmadja; Taralan Tambunan; Rulina Suradi
Paediatrica Indonesiana Vol 46 No 6 (2006): November 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.002 KB) | DOI: 10.14238/pi46.6.2006.266-70

Abstract

Background Neonatal seizures or fits are signs of central ner-vous system (CNS) diseases, metabolic disorders, or other dis-eases disrupting the CNS. Neonatal seizures are poorly classi-fied, under-recognized and often difficult to treat. It is important torecognize the type of neonatal seizures that might be the only signof a CNS disorder.Objective To recognize the type and etiology of neonatal sei-zures in several hospitals in Jakarta.Methods This was an observational case series study on full-termand preterm infants who had seizures during hospitalization in CiptoMangunkusumo, Harapan Kita, and Fatmawati Hospitals betweenJanuary-June 2005. Neonatal seizures were defined as seizuresoccurring in the first 28 days of life of a term infant or 44 completedweeks of the infant’s conception age of preterm infant.Results There were 40 neonates who born within the study periodand had seizures. Girls were outnumbered boys. Most neonateswere full-term with birth weight of more than 2500 grams. Analy-ses were done on 38 neonates with epileptic and non-epilepticseizures, while the other two who had mixed clinical manifestationwere not included. Most seizures occurred in the first 3 days of life(23/38). The most common type was focal clonic (12/14) followedby general tonic (11/24) and motor automatism or subtle (10/24).The most common etiology was hypoxic ischemic encephalopa-thy (HIE) (19/38) followed by metabolic disturbances, mainly hy-pocalcaemia (11/38).Conclusion Common types of seizures in neonates were focalclonic, general tonic, and motor automatism (subtle). The mostcommon etiology was HIE followed by metabolic disturbances,mainly hypocalcaemia
Vesico-Ureteral Reflux and Reflux Nephropathy in Children with Recurrent Urinary Tract Infection Taralan Tambunan
Paediatrica Indonesiana Vol 36 No 11-12 (1996): November - December 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (549.792 KB) | DOI: 10.14238/pi36.11-12.1996.239-47

Abstract

We reviewed clinical and laboratory findings of patients with recurrent urinary Uact infections (UTI) to detect the presence of vesico-ureteral reflux (VUR) or reflux nephropathy (RN). Only patients with evidence of more than 2 bouts of UTI's treated at the Department of Child Health, Cipto Mangunkusumo Hospital during the period from October 1, 1992 to September 30, 1993 were studied. There were 30 pa­tients (15 boys, 15 girls) ranging in age from 2 months to 16 years (mean age = 5.5 years). RN as detected on dimercaptosuccinic acid (DMSA) scanning was found in 21 patients (12 unilateral, 9 bilateral). Mictiocyctourography (MCU) was done in 22 patients, revealing VUR in 14 patients, 10 of them showed renal scarring on DMSA scanning. Most of die patients has the duration of illness of less than 2 years. Clinical symptoms and signs (hypertension, proteinuria, increased plasma urea / creatinine) alone or in combination were more commonly found in patients with RN than in those without RN. The high prevalence of VUR and RN in patients with recurrent UTI in our senes (63% and 70%, respectively), should draw our attention to detect UTI in its earliest stage, to be able to treat the patient promptly in order to prevent RN which eventually progresses into renal failure.
Effect of Recombinant Erythropoeitin in Anemia Due to Chronic Renal Failure Husein Alatas; Fahrul W. Arbi; Taralan Tambunan; I.G.N. Wita Wirya
Paediatrica Indonesiana Vol 37 No 5-6 (1997): May - June 1997
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (405.06 KB) | DOI: 10.14238/pi37.5-6.1997.124-31

Abstract

Recombinant human erythropoeitin (rHuEPO) was administered to 16 patients hospitalized at the Department of Child Health Faculty of Medicine University of Indonesia Cipto Mangunkusumo Hospital between July 1992 until December 1994, with anemia (Hb < 8 g dl) due to chronic renal failure (creatinine uclearance < 30 ml/min/1.3 mJ). three of them with end stage renal failure (creatinine clearance < 5 ml/min/1.73 nr). The average age was 15.9 years (range 4-16 years) the proportion of sex were the same. An initial dose of 150 lU/kgBW/week rHuEPO was administered subcutaneously. The dose was increased by 75 U/kgBW/week and maintained when the hemoglobin level reached 11 g/dl. Good result was mostly found at the dose of 150-199 IU/kgBW/week. The hemoglobin level rose from 6.79 + 1.19/dl before treatment to 10.4 + 3.9 g/dl after treaunent (p=0.011). Six cases failed to reach Hb 1 lg/dl, one of them with severe hypertension while in the other case had peritonitis. Decrease of the serum ferritin level during treatment indicated that ferrum was utilized for erythropoesis. This study showed that in chronic renal insufficiency we should consider to give r-HuEPO to increase hemoglobin to avoid giving recurrent blood tranfusion; however, the cost may limit its widespread use.
Co-Authors Aman B. Pulungan Arwin Akib Aswitha D. Boediarso Atiek Widya Oswari Badriul Hegar Bambang Tridjaja AAP, Bambang Tridjaja Daisy Widiastuti Edi S Tehuteru Eveline P N Fahrul W. Arbi Felliyani Felliyani Husein Alatas I.G.N. Wita Wirya Idham Amir Irawan Mangunatmadja Irene Yuniar, Irene Iswari Setianingsih Jose RL Batubara Lineus Hewis Mardjanis Said Partini P Trihono Rianita Syamsu Rulina Suradi Sri Rezeki S Hadinegoro Sri S Nasar Sudigdo Sastroasmoro Sudung O Pardede Syarif Faisal Vera M Manoe Yulia Iriani, Yulia ZAINUL ARIFIN