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All Journal Indonesian Journal of Cancer Chemoprevention Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Majalah Farmaseutik JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ilmu Kefarmasian Indonesia Borneo Journal of Pharmacy
Sylvia Utami Tunjung Pratiwi
Faculty Of Pharmacy, Universitas Gadjah Mada. Yogyakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Nanoemulsion Mouthwash Formulation of Bajakah Tampala (Spatholobus littoralis Hassk.) Skin Extract Against Candida albicans Hamzah, Hasyrul; Gunawan, Dede Reza; Pratiwi, Sylvia Utami Tunjung; Bakhtiar, Muh. Irham; Pratama, Virgiawan Yoga; Subhan, Muhammad; Maulana, Riza
Borneo Journal of Pharmacy Vol. 7 No. 1 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i1.5548

Abstract

Candida albicans can cause two infections in humans: superficial and systemic. The ability of C. albicans to infect the host is influenced by virulence factors and character changes so that it can fool the immune system. From the character change factor, C. albicans can form a biofilm. This study aims to determine the good concentration in inhibiting and determine the antifungal and antibiofilm activity of nanoemulsion mouthwash formulation of bajakah tampala (Spatholobus littoralis Hassk) skin extract against C. albicans. This research was conducted with an experimental method. The formulation used a spontaneous magnetic stirrer technique to make nanoemulsion preparations. Antifungal and antibiofilm tests were carried out by dilution method using a 96-well plate and a microplate reader with a wavelength of 620 nm to determine the percentage inhibition against C. albicans and determine MIC50 and MBIC50. The results showed that the nanoemulsion mouthwash formulation of S. littoralis inhibited the planktonic and biofilm of C. albicans. The concentration of 1% is expressed as MIC50 and MBIC50. Therefore, the nanoemulsion formulation of S. littoralis extract could inhibit the growth of C. albicans in the oral cavity.
Co-Authors Aini Febriana Ardani, Marisya Bakhtiar, Muh. Irham Dian Mayasari Ema Damayanti FERRY RAHMA PUSPITA Fita Rahmawati Fransisca Priskaningtyas Wulandari Gunawan, Dede Reza Hamzah, Hasyrul Iramie Duma Kencana Irianto Joselin Ekaputri Khoirunnissa Hida MAULANA, RIZA Meiliana Meiliana Meta Juniatik Muhammad Subhan Ni'matul Munawaroh NURI IRIYANI Nurul Pangestuti Pratama, Virgiawan Yoga Rafika Sari Rina Kuswahyuning Ronny Martien Shinta Sari Dewi SINTAYU PUTRI WANDAN SARI Sudarsono Sudarsono Titik Nuryastuti Triana Hertiani Yosi Bayu Murti