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Journal : Lumbung Farmasi : Jurnal Ilmu Kefarmasian

Evaluasi Penggunaan Obat Anti-Tuberkulosis dan Clinical Outcome Pasien Tuberkulosis Ekstra Paru di Rumah Sakit Paru Dr. M Goenawan Partowidigdo Rokhmah, Nisa Najwa; Gunawan, Dewi Oktavia; Ningsih, Whidya
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 1 (2025): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i1.24712

Abstract

Extra-pulmonary tuberculosis is tuberculosis that causes involvement of organs outside the lung parenchyma. Data detected tuberculosis cases in Indonesia were 717,941 cases, about 20-25% of tuberculosis cases occurred outside the lungs. This study was a descriptive analysis with retrospective data collection conducted at RSPG. Data were analyzed by means of descriptive univariate analysis and bivariate analysis using chi-square statistics. The use of anti-tuberculosis drugs in extra-pulmonary tuberculosis patients using first-line treatment, namely: Rifampicin, Isoniazid, Pyrazinamide and Ethambuthol. The results of the Clinical Outcome analysis of 50 patients based on the parameters of clinical symptoms, body weight, BTA test results and Thorax X-rays, namely there were 40 patients (80%) who experienced improvement in clinical symptoms, 42 patients (84%) experienced weight gain, 50 patients (100%) did not experience changes in BTA test results and 36 patients (72%) who experienced improvement in Thorax X-ray examination results. The results of Chi-square analysis showed that there was a significant influence between anti-tuberculosis treatment on Clinical Outcome based on patient clinical symptoms (p<0.05).