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All Journal Pharmacology and Clinical Pharmacy Research Jambura Journal of Health Sciences and Research JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA) Jurnal Indah Sains dan Klinis
Yessi Febriani
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EDUKASI MASYARAKAT : “HIDUP SEHAT PADA LANSIA DI MASA PANDEMIK COVID-19” DI KOMUNITAS BELAJAR RUMAH AYAH JOHOR Pravil Mistryanto Tambunan; Eva Sartika Dasopang; Anna Juniar; Ratih Paramitha; Yessi Febriani; Supran Hidayat Sihotang; Nurmala Sari; Mariany Razali; Vriezka Mierza
JUKESHUM: Jurnal Pengabdian Masyarakat Vol. 1 No. 2 (2021): Edisi Juli 2021
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (933.153 KB) | DOI: 10.51771/jukeshum.v1i2.87

Abstract

Telah dilakukan kegiatan edukasi kepada masyarakat dengan mengusung tema : “Hidup Sehat Pada Lansia di Masa Pandemik COVID-19”. Edukasi dilakukan oleh tim gabungan yang terdiri atas sejumlah dosen perguruan tinggi negeri dan swasta di kota Medan. Sasaran edukasi ini adalah masyarakat kelompok lansia maupum yang merawat lansia di rumah yang bermukim di daerah Medan Johor, tepatnya di Komunitas Belajar Rumah Ayah (Fadlan Institute) yang terletak di Jl. Karya Muda No. 7. Adapun kegiatan dimulai dengan senam pagi bersama dan diikuti dengan pemaparan materi serta sesi tanya jawab. Para peserta dalam edukasi ini menunjukkan antusiasme yang tinggi terutama Komunitas Senam Sehat Ceria Karya Muda yang secara rutin melakukan kegiatan senam dengan protokol kesehatan disana. Dari hasil edukasi, masyarakat terutama kaum lansia dan yang merawat lansia semakin mengerti bahwa pola hidup sehat termasuk olahraga teratur, makan makanan yang bergizi seimbang, serta menerapkan protokol kesehatan harus tetap dijalankan secara konsisten di masa pandemik ini.
Toxicity Assay of Fermented Artocarpus altilis Leaves Using Brine Shrimp Lethality Test Hesti Riasari; Yessi Febriani; Winda A. Nurfauziah
Pharmacology and Clinical Pharmacy Research Vol 4, No 2
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.738 KB) | DOI: 10.15416/pcpr.v4i2.24525

Abstract

Fermented  Artocarpus altilis leaves contains phenolic compound  that has pharmacological activity. Differences in fermentation method, i.e., aerobic and anaerobic fermentation might change its characteristics and biological activity. The purpose of this study was to compare toxicity properties between aerobically and anaerobically fermented  Artocarpus altilis leaves  using brine shrimp lethality (BSL) test. Both types of fermented leaves were cold extracted using ethanol solvent (1:6) for 3 x 24 hours. Phytochemical screening was then performed to examine the presence of secondary metabolite compounds. BSL test was performed in 7 treatment groups, i.e., negative control, 1000, 500, 100, 50, 25, 12.5 ppm of extract. Each vial contained 10 Artemia larvae, extract, and sea water up to 10 ml. Toxicity is measured by calculating LC50 after 24 hours observation. The  experiment was repeated three times. The results of the study showed that LC50 of aerobic extract was 712 ppm, thus it can be categorized as toxic, while that of anaerobic extract is 1.927 ppm, or non-toxic to the Artemia salina larvae. In conclusion, aerobically fermented  Artocarpus altilis leaves had toxicity potency, while anaerobically fermented  Artocarpus altilis leaves had no toxicity potency against Artemia salina in BSL test. Key words: Artocarpus altilis, brine shrimp lethality test, toxicity.
EFFECTIVENESS OF BUTTERFLY PEA ETHANOL EXTRACT ON DECREASING BLOOD GLUCOSE LEVELS OF MALE MICE Erica Mega Valentine Simangunsong; Yessi Febriani; Muharni Saputri; Dina Arisa; Ghianti Zarqa Afifah
Jambura Journal of Health Sciences and Research Vol 5, No 2 (2023): APRIL: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v5i2.18789

Abstract

Butterfly pea flower (Clitoria Ternatea L.) contains flavonoids, tannins, and triterpenoids, which contain flavonoid compounds that have the potential as antioxidants. Antioxidants can suppress beta cell apoptosis without changing the proliferation of pancreatic beta cells. Antioxidants can bind free radicals so that they can reduce insulin resistance. The novelty of this study was that it examined the effectiveness of ethanol extract from butterfly pea flowers on reducing alloxan-induced male mice blood glucose levels. This study aimed to determine the effectiveness of the ethanol extract of butterfly pea flowers in reducing alloxan-induced blood glucose levels. The study used an experimental method with 5 treatments on 25 mice, beginning with purposive collection and processing of sample plants, preparation of Simplicia powder, preparation of ethanol extract of butterfly pea flowers, characteristic testing, determination of total ash content, determination of acid insoluble ash content, determination of extract content. Soluble in water, determination of ethanol soluble extract content, determination of water content, phytochemical screening, testing of antidiabetic activity of butterfly pea flower extract induced by alloxan. The examination results contained a total ash content of 5.20%, an acid-insoluble ash content of 1.16%, a water-soluble essence content of 47.94%, and a water content of 3.29%. The results of the compounds in the ethanol extract of butterfly pea flowers are alkaloids, flavonoids, tannins, saponins, and steroids. The results of testing blood glucose levels of ethanol extract of butterfly pea flower (EEBT) at a dose of 200mg/kg bb were known to be effective in reducing blood glucose after being induced by alloxan 150mg/kg bb with glucose levels of 319mg/dL dropping to 104.93mg/dL. The conclusion of the ethanol extract of the butterfly pea flower shows that the butterfly pea flower is efficacious as a blood glucose lowering agent in alloxan-induced mice (Mus musculus).
Comparison Of Formulations And Antioxidant Activity Of Transparent Soap From Red And Black Plum (Prunus domestica L.) Yessi Febriani; Mierza, Vriezka; Septimar, Elviza
Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA) Vol. 1 No. 2 (2021): September: Mathematics and natural science
Publisher : Lembaga Layanan Pendidikan Tinggi Wilayah I Sumatra Utara (LLDikti I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54076/jumpa.v1i2.45

Abstract

Transparent soap is a type of soap for the face and body to cleanse and protect the skin from free radicals. Plums are fruits that have very high antioxidant capabilities, because they have the content of flavonoids and tannins. This research aims to make transparent soap with the addition of red and black plum juice and compare the antioxidant activity capabilities of soap. This research captures the process of taking cider, phytochemical screening, and soap making. Analysis is pH test, moisture content, foam stability, free alkaline, and antioxidant activity test with DPPH method. The results of the antioxidant activity test are very strong with a value of IC50 < 50 ppm namely red plum juice (30.83 ppm), black plum juice (47.74 ppm), red plum soap (16.52 ppm), black plum soap (12.08 ppm). Soap has a pH of negative blanko (8.5), positive blanko (8.3), red plum (8.6), black plum (8.0). Water content of blanko soap is negative (1.88), blanko positive (2.69), red plum (1.76), black plum (1.83). Negative blanko soap foam stability (50), positive blanko (20), red plum (45), black plum (65), and alkaline free negative blanko soap (0.04), positive blanko (0.08), red plum (0.05), black plum (0.06). Transparent soap meets the quality requirements in accordance with SNI 3532:2016.
Antioxidant Activity and Total Flavonoid of Extract of Bark Vitex pinnata L. Zulfan; Yessi Febriani; Sumardi
Jurnal Indah Sains dan Klinis Vol 4 No 3 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i3.04

Abstract

Background: The bark of Vitex pinnata L is not yet optimally utilized, primarily being used in boat construction while the remaining material becomes waste that is either buried or burned in trash. Therefore, it is necessary to explore more efficient and economically valuable uses for the bark of the laban tree. Objective: The aim of this research is to identify the chemical compounds, flavonoid content, and antioxidant activity present in the methanol extract of Vitex pinnata L bark. Method: Phytochemical screening was conducted on the methanol extract of Vitex pinnata L. bark. To obtain the extract, the simplicia powder was macerated using methanol as the solvent. The total flavonoid content and antioxidant activity were then tested using the 1,1-diphenyl-2-picryhydrazil (DPPH) method. Results: the phytochemical screening indicated that the Vitex pinnata L. bark extract contains alkaloids, flavonoids, and tannins. The total flavonoid test yielded 17.27%, and the antioxidant activity test revealed that the methanol extract of the laban tree bark has antioxidant activity with an IC50 value of 43.22 ppm. Conclusion: This extract has strong potential as an antioxidant agent.
Kenali Penyakit Diabetes Mellitus Untuk Hidup Lebih Sehat Eva Sartika Dasopang; siti rahmi ningrum; yessi Febriani; supran hidayat; karolina sitepu; Hajatina Hajatina
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 3 No 1 (2024): Edisi Januari 2024 - Juni 2024
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v3i1.1006

Abstract

Penyakit Diabetes Mellitus, yang disebabkan oleh kegagalan sekresi dan kerja insulin, terus menjadi perhatian global, terutama di negara-negara berkembang. Fokus utama pengabdian masyarakat ini adalah untuk memberikan edukasi dan meningkatkan pengetahuan masyarakat, khususnya siswa-siswi, tentang Diabetes Mellitus guna mencapai gaya hidup yang lebih sehat. Tujuan dilaksanakannnya pengabdian ini adalah untuk memberikan pemahaman yang komprehensif mengenai penyakit ini, termasuk penyebab, dampak, dan cara pencegahan. Dengan memfokuskan edukasi pada generasi muda, diharapkan pesan tentang pentingnya hidup sehat dapat diinternalisasi sejak dini. Metode pelaksanaan kegiatan mencakup penyampaian informasi melalui ceramah yang informatif dan interaktif. Hasil kegiatan ini mencerminkan peningkatan kesadaran masyarakat, terlihat dari partisipasi aktif siswa-siswi dalam sesi tanya jawab dan diskusi. Melalui pendekatan edukatif ini, diharapkan masyarakat dapat mengambil langkah-langkah preventif dan memperbaiki gaya hidup mereka, sehingga meningkatkan kualitas hidup secara keseluruhan. Pengabdian ini memberikan kontribusi pada upaya global untuk mengatasi masalah kesehatan publik yang terus berkembang, dengan memfokuskan pada edukasi sebagai langkah awal yang penting.
Co-Authors Anna Juniar Dina Arisa Erica Mega Valentine Simangunsong Eva Sartika Dasopang Ghianti Zarqa Afifah Hajatina Hajatina Hesti Riasari Karolina Sitepu Mariany Razali Mierza, Vriezka Muharni Saputri Nurmala Sari Pravil Mistryanto Tambunan Ratih Paramitha Septimar, Elviza siti rahmi ningrum Sumardi Supran Hidayat Supran Hidayat Sihotang Vriezka Mierza Winda A. Nurfauziah Zulfan